FI97551B - Analysmetod, reagenskomposition och användning därav för glukosbestämning - Google Patents
Analysmetod, reagenskomposition och användning därav för glukosbestämning Download PDFInfo
- Publication number
- FI97551B FI97551B FI915020A FI915020A FI97551B FI 97551 B FI97551 B FI 97551B FI 915020 A FI915020 A FI 915020A FI 915020 A FI915020 A FI 915020A FI 97551 B FI97551 B FI 97551B
- Authority
- FI
- Finland
- Prior art keywords
- nicotinamide
- glucose
- phenazine
- whole blood
- nad
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/54—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving glucose or galactose
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Analytical Chemistry (AREA)
- Emergency Medicine (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Claims (5)
1. Metod för kvantitativ bestämnlng av totalglukos 1 outspätt helblod, kännetecknad därav, att 5 ett prov av outspätt helblod bringas i kontakt med ett reagens i torr from som innefattar: glukosdehydrogenas (GDH); ett eller flera av ämnena diaforas, fenazin-metosulfat, fenazinetosulfat, fenazinfenosulfat och Meldo- 10 la blue; ett eller flera av ämnena NAD, NADP, tio-NAD, tio-NADP, nikotinamidpurin-dinukleotid, nikotinamid-metylpu-rin-dinukleotid, nikotinamid-2-klor-metylpurin-dinukleo-tid; 15 ett eller flera av de hemolyserande ämnena fosfoli pas, hemolyserande saponlner samt föreningar mellan hydro-fila mono-, di- eller trisackarider och alifatiska kolvä-ten med 10-16 kolatomer; en redoxindikatorfärg, som är ett tetrazoliumsalt; 20 och eventuellt mutarotas; samt att en färgförändring som uppkommit genom reagensets reaktion med glukos i det outspädda helblodet mäts med trans-missionspektrofotometri.
2. Metod enligt patentkrav 1, känneteck nad därav, att provet av helblod ges en volym pä mind-re än 20 mikroliter.
3. Reagenskompositiön för kvantitativ bestämning av totalglukos i outspätt helbold, kännetecknad 30 därav, att den föreligger i torr form och att den inne-fattar: glukosdehydrogenas (GDH); ett eller flera av ämnena diaforas, fenazinmetosul-fat, fenazinetosulfat, fenazinfenosulfat och Meldola blue; 35 ett eller flera av ämnena NAD, NADP, tio-NAD, tio- NADP, nikotinamidpurin-dinukleotid, nikotinamid-metylpu- 97551 15 rin-dinukleotid, nikotinamid-2-klor-6-metylpurin-dinuk-leotld; ett eller flera av de hemolyserande ämnena fosfoli-pas, hemolyserade saponiner samt föreningar me11an hydro-5 fila mono-, dl- eller trisackarider och alifatiska kolvä-ten med 10 - 16 kolatomer; en redoxinidikatorfärg, som är ett tetrazoliumsalt; och eventuellt mutarotas.
4. Reagenskomposition enligt patentkrav 3, k ä n - netecknad därav, att den innefattar: glukosdehydrogenas, diaforas, NAD, 15 ett eller flera saponin, ett tetrazoliumsalt, och eventuellt mutarotas.
5. Användning av en reagenskomposition, vilken komposition innefattar: 20 glukosdehydrogenas (GDH); ett eller flera av ämnena diaforas, fenazinmetosul-fat, fenazinetosulfat, fenazinfenosulfat och Meldola blue; ett eller flera av ämnena NAD, NADP, tio-NAD, tio-NADP, nikotinamidpurin-dinukleotid, nikotinamid-metylpu-25 rin-dinukleotid, nikotinamid-2-klor-metylpurin-dinukleo- tid; ett eller flera av de hemolyserande ämnena fosfolipas, hemolyserande saponiner samt föreningar mellan hydro-fila mono-, di- eller trisackarider och alifatiska kolvä-30 ten med 10-16 kolatomer; en redoxinidikatorfärg, som är ett tetrazoliumsalt; och eventuellt mutarotas, och vilken komposition föreligger i torr form, för utför-35 ande av en kvantitativ bestäming av totalglukos i outspätt helblod med hjälp av transmissionsspektrofotometri.
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE8901515A SE466158B (sv) | 1989-04-25 | 1989-04-25 | Analysmetod foer glukosbestaemning i helblod |
| SE8901515 | 1989-04-25 | ||
| PCT/SE1990/000272 WO1990012889A1 (en) | 1989-04-25 | 1990-04-24 | Method of analysis, reagent composition and use thereof for glucose determination |
| SE9000272 | 1990-04-24 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| FI915020A0 FI915020A0 (sv) | 1991-10-24 |
| FI97551B true FI97551B (sv) | 1996-09-30 |
| FI97551C FI97551C (sv) | 1997-01-10 |
Family
ID=20375802
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI915020A FI97551C (sv) | 1989-04-25 | 1991-10-24 | Analysmetod, reagenskomposition och användning därav för glukosbestämning |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US5278047A (sv) |
| EP (1) | EP0470201B1 (sv) |
| JP (1) | JPH0734757B2 (sv) |
| KR (1) | KR960001139B1 (sv) |
| AT (1) | ATE122102T1 (sv) |
| AU (1) | AU637612B2 (sv) |
| BR (1) | BR9007339A (sv) |
| CA (1) | CA2053315C (sv) |
| DE (1) | DE69019149T2 (sv) |
| DK (1) | DK0470201T3 (sv) |
| ES (1) | ES2071821T3 (sv) |
| FI (1) | FI97551C (sv) |
| LT (1) | LT3136B (sv) |
| LV (1) | LV10122B (sv) |
| NO (1) | NO300853B1 (sv) |
| RU (1) | RU2050546C1 (sv) |
| SE (1) | SE466158B (sv) |
| WO (1) | WO1990012889A1 (sv) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6073977A (en) * | 1994-09-08 | 2000-06-13 | Lindab Ab | Device for coupling pipe sections |
| DK9500486U3 (da) * | 1995-12-18 | 1997-04-11 | Lindab As | Indretning til sammenkobling af rørstykker |
| EP1082006B1 (en) | 1998-05-26 | 2006-02-01 | Lifecell Corporation | Cryopreservation of human red blood cells |
| US6312888B1 (en) | 1998-06-10 | 2001-11-06 | Abbott Laboratories | Diagnostic assay for a sample of biological fluid |
| US6077660A (en) * | 1998-06-10 | 2000-06-20 | Abbott Laboratories | Diagnostic assay requiring a small sample of biological fluid |
| US5902731A (en) * | 1998-09-28 | 1999-05-11 | Lifescan, Inc. | Diagnostics based on tetrazolium compounds |
| US6656697B1 (en) * | 1998-09-28 | 2003-12-02 | Lifescan, Inc. | Diagnostics based on tetrazolium compounds |
| LT4605B (lt) | 1999-04-07 | 2000-01-25 | Biochemijos Institutas | Fermentinis gliukozės sensorius ir jo gavimo būdas |
| US6485923B1 (en) | 2000-02-02 | 2002-11-26 | Lifescan, Inc. | Reagent test strip for analyte determination having hemolyzing agent |
| PL357180A1 (en) * | 2000-03-28 | 2004-07-26 | Lifescan, Inc. | Reagent systems for detecting the presence of a reduced cofactor in a sample and methods for using the same |
| US6368818B1 (en) * | 2000-10-12 | 2002-04-09 | Qingzhong Kong | Methods and compositions for the visualization of cellular organelles using tetrazolium salts |
| US6420128B1 (en) * | 2000-09-12 | 2002-07-16 | Lifescan, Inc. | Test strips for detecting the presence of a reduced cofactor in a sample and method for using the same |
| US20040096927A1 (en) * | 2000-09-13 | 2004-05-20 | Chittock Roger Steward | Method for the detection and measurement of biomass |
| US7524872B2 (en) * | 2000-09-15 | 2009-04-28 | Qingzhong Kong | Method and composition for treating cancer using cellular organelle crystallizing agents |
| US7785771B2 (en) * | 2004-12-17 | 2010-08-31 | Megazyme Ip Limited | Assay for determination of free D-galactose and/or L-arabinose |
| WO2006064488A1 (en) * | 2004-12-17 | 2006-06-22 | Megazyme Ip Limited | A kit for colorimetric assays of food and beverage analytes |
| KR100793852B1 (ko) * | 2005-03-21 | 2008-01-11 | 김영기 | 착즙주스기 |
| KR100776914B1 (ko) | 2005-06-14 | 2007-11-15 | 주식회사 엘지화학 | 온도 측정 장치 |
| WO2008030154A1 (en) * | 2006-09-08 | 2008-03-13 | Hemocue Ab | Haemolysing agent |
| US8008037B2 (en) * | 2008-03-27 | 2011-08-30 | Roche Diagnostics Operations, Inc. | Matrix composition with alkylphenazine quaternary salt and a nitrosoaniline |
| KR101239381B1 (ko) * | 2012-05-02 | 2013-03-05 | 주식회사 아이센스 | 산화환원반응용 시약의 안정제 조성물 |
| CN103088108A (zh) * | 2012-11-16 | 2013-05-08 | 李立和 | 葡萄糖脱氢酶法检测葡萄糖的试剂盒及制备方法 |
| US9347958B2 (en) | 2014-06-27 | 2016-05-24 | Hemocue Ab | Device and method for determination of an analyte in blood |
| CN106018296A (zh) * | 2016-05-20 | 2016-10-12 | 大连大学 | 蓝莓中总黄酮含量的测定 |
| CN106018297A (zh) * | 2016-05-20 | 2016-10-12 | 大连大学 | 蓝莓中总黄酚含量的测定 |
| CN110715923A (zh) * | 2019-11-24 | 2020-01-21 | 天津市宝坻区人民医院 | α-D-葡萄糖检测试剂盒 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CS164231B2 (sv) * | 1972-09-28 | 1975-11-07 | ||
| DE2349819A1 (de) * | 1973-10-04 | 1975-04-17 | Eppendorf Geraetebau Netheler | Verfahren zur enzymkinetischen konzentrationsbestimmung eines substrats |
| US4120755A (en) * | 1977-04-28 | 1978-10-17 | Beckman Instruments, Inc. | Kinetic method for determination of glucose concentrations with glucose dehydrogenase |
| US4975367A (en) * | 1986-04-04 | 1990-12-04 | Miles Inc. | Catalytic test composition intended to produce a range of colors |
| US4898813A (en) * | 1986-04-04 | 1990-02-06 | Albarella James P | Catalytic test composition intended to produce a range of colors |
| US5059394A (en) * | 1986-08-13 | 1991-10-22 | Lifescan, Inc. | Analytical device for the automated determination of analytes in fluids |
-
1989
- 1989-04-25 SE SE8901515A patent/SE466158B/sv not_active IP Right Cessation
-
1990
- 1990-04-24 DE DE69019149T patent/DE69019149T2/de not_active Expired - Lifetime
- 1990-04-24 RU SU905010235A patent/RU2050546C1/ru active
- 1990-04-24 WO PCT/SE1990/000272 patent/WO1990012889A1/en active IP Right Grant
- 1990-04-24 AU AU55575/90A patent/AU637612B2/en not_active Ceased
- 1990-04-24 JP JP2507031A patent/JPH0734757B2/ja not_active Expired - Fee Related
- 1990-04-24 US US07/768,249 patent/US5278047A/en not_active Expired - Lifetime
- 1990-04-24 AT AT90908121T patent/ATE122102T1/de not_active IP Right Cessation
- 1990-04-24 BR BR909007339A patent/BR9007339A/pt not_active IP Right Cessation
- 1990-04-24 CA CA002053315A patent/CA2053315C/en not_active Expired - Lifetime
- 1990-04-24 DK DK90908121.8T patent/DK0470201T3/da active
- 1990-04-24 EP EP90908121A patent/EP0470201B1/en not_active Expired - Lifetime
- 1990-04-24 ES ES90908121T patent/ES2071821T3/es not_active Expired - Lifetime
- 1990-04-24 KR KR1019910701447A patent/KR960001139B1/ko not_active IP Right Cessation
-
1991
- 1991-10-24 FI FI915020A patent/FI97551C/sv active
- 1991-10-24 NO NO914181A patent/NO300853B1/no not_active IP Right Cessation
-
1992
- 1992-12-17 LV LVP-92-308A patent/LV10122B/en unknown
- 1992-12-30 LT LTIP275A patent/LT3136B/lt not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| NO914181D0 (no) | 1991-10-24 |
| FI915020A0 (sv) | 1991-10-24 |
| RU2050546C1 (ru) | 1995-12-20 |
| KR960001139B1 (ko) | 1996-01-19 |
| JPH04504661A (ja) | 1992-08-20 |
| SE8901515D0 (sv) | 1989-04-25 |
| DE69019149D1 (de) | 1995-06-08 |
| AU5557590A (en) | 1990-11-16 |
| WO1990012889A1 (en) | 1990-11-01 |
| EP0470201B1 (en) | 1995-05-03 |
| LTIP275A (en) | 1994-07-15 |
| JPH0734757B2 (ja) | 1995-04-19 |
| DK0470201T3 (da) | 1995-07-17 |
| NO300853B1 (no) | 1997-08-04 |
| KR920701476A (ko) | 1992-08-11 |
| EP0470201A1 (en) | 1992-02-12 |
| CA2053315A1 (en) | 1990-10-26 |
| SE466158B (sv) | 1992-01-07 |
| US5278047A (en) | 1994-01-11 |
| CA2053315C (en) | 2000-07-04 |
| SE8901515L (sv) | 1990-10-26 |
| NO914181L (no) | 1991-10-24 |
| ES2071821T3 (es) | 1995-07-01 |
| ATE122102T1 (de) | 1995-05-15 |
| AU637612B2 (en) | 1993-06-03 |
| BR9007339A (pt) | 1992-04-28 |
| DE69019149T2 (de) | 1995-09-07 |
| LV10122A (lv) | 1994-05-10 |
| FI97551C (sv) | 1997-01-10 |
| LT3136B (en) | 1995-01-31 |
| LV10122B (en) | 1995-02-20 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| BB | Publication of examined application |