FI972641L - Kalkonit ja niiden esterit, joilla on antiproliferatiivinen vaikutus kohtu-, munasarja- ja rintakasvaimiin - Google Patents
Kalkonit ja niiden esterit, joilla on antiproliferatiivinen vaikutus kohtu-, munasarja- ja rintakasvaimiin Download PDFInfo
- Publication number
- FI972641L FI972641L FI972641A FI972641A FI972641L FI 972641 L FI972641 L FI 972641L FI 972641 A FI972641 A FI 972641A FI 972641 A FI972641 A FI 972641A FI 972641 L FI972641 L FI 972641L
- Authority
- FI
- Finland
- Prior art keywords
- chalcones
- uterine
- ovarian
- esters
- breast tumors
- Prior art date
Links
- 208000026310 Breast neoplasm Diseases 0.000 title 1
- DQFBYFPFKXHELB-UHFFFAOYSA-N Chalcone Natural products C=1C=CC=CC=1C(=O)C=CC1=CC=CC=C1 DQFBYFPFKXHELB-UHFFFAOYSA-N 0.000 title 1
- 206010061535 Ovarian neoplasm Diseases 0.000 title 1
- 230000001028 anti-proliverative effect Effects 0.000 title 1
- 150000001789 chalcones Chemical class 0.000 title 1
- 235000005513 chalcones Nutrition 0.000 title 1
- 150000002148 esters Chemical class 0.000 title 1
- 230000002611 ovarian Effects 0.000 title 1
- 208000025421 tumor of uterus Diseases 0.000 title 1
- 206010046766 uterine cancer Diseases 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/12—Ketones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/017—Esters of hydroxy compounds having the esterified hydroxy group bound to a carbon atom of a six-membered aromatic ring
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines Containing Plant Substances (AREA)
- Steroid Compounds (AREA)
- Indole Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ITMI942568A IT1271301B (it) | 1994-12-20 | 1994-12-20 | Calconi naturali e sintetici e loro esteri ad attivita' antiproliferativa nei tumori dell'utero,dell'ovaio e del seno e formulazioni che li contengono |
| PCT/EP1995/004770 WO1996019209A1 (en) | 1994-12-20 | 1995-12-04 | Chalcones and esters thereof with antiproliferative activity in uterus, ovary and breast tumours |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| FI972641A0 FI972641A0 (fi) | 1997-06-19 |
| FI972641A7 FI972641A7 (fi) | 1997-08-14 |
| FI972641L true FI972641L (fi) | 1997-08-14 |
Family
ID=11370023
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI972641A FI972641L (fi) | 1994-12-20 | 1995-12-04 | Kalkonit ja niiden esterit, joilla on antiproliferatiivinen vaikutus kohtu-, munasarja- ja rintakasvaimiin |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US5808137A (cs) |
| EP (1) | EP0800387B1 (cs) |
| JP (1) | JP2004131509A (cs) |
| KR (1) | KR100264369B1 (cs) |
| CN (1) | CN1087609C (cs) |
| AT (1) | ATE222756T1 (cs) |
| AU (1) | AU689357B2 (cs) |
| CA (1) | CA2208351C (cs) |
| CZ (1) | CZ288043B6 (cs) |
| DE (1) | DE69527980T2 (cs) |
| DK (1) | DK0800387T3 (cs) |
| ES (1) | ES2181806T3 (cs) |
| FI (1) | FI972641L (cs) |
| HU (1) | HU225501B1 (cs) |
| IT (1) | IT1271301B (cs) |
| NO (1) | NO307926B1 (cs) |
| PL (1) | PL183772B1 (cs) |
| PT (1) | PT800387E (cs) |
| RU (1) | RU2181284C2 (cs) |
| SI (1) | SI9520139B (cs) |
| SK (1) | SK282259B6 (cs) |
| WO (1) | WO1996019209A1 (cs) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9712966D0 (en) * | 1997-06-19 | 1997-08-27 | Indena Spa | Novel chalcones |
| US6423740B1 (en) | 1997-06-19 | 2002-07-23 | Indena S.P.A. | Chalcones having antiproliferative activity |
| US6239114B1 (en) * | 1997-09-26 | 2001-05-29 | Kgk Synergize | Compositions and methods for treatment of neoplastic diseases with combinations of limonoids, flavonoids and tocotrienols |
| GB9920910D0 (en) | 1999-09-03 | 1999-11-10 | Indena Spa | Novel chalcones |
| GB9920908D0 (en) * | 1999-09-03 | 1999-11-10 | Indena Spa | Chalcone coumarins |
| US6608101B1 (en) | 2000-06-20 | 2003-08-19 | Atherogenics, Inc. | 1, 3-bis-(substituted-phenyl)-2-propen-1-ones and their use to treat VCAM-1 mediated disorders |
| US6545007B2 (en) | 2000-11-17 | 2003-04-08 | Idenix (Cayman) Limited | Methods for inhibiting the transmission of HIV using topically applied substituted 6-benzyl-4-oxopyrimidines |
| CA2470931A1 (en) * | 2001-12-19 | 2003-07-03 | Atherogenics, Inc. | Chalcone derivatives and their use to treat diseases |
| US7514579B2 (en) * | 2002-06-13 | 2009-04-07 | Johns Hopkins University | Boronic chalcone derivatives and uses thereof |
| AU2003303239A1 (en) * | 2002-12-19 | 2004-07-14 | Atherogenics, Inc. | Process of making chalcone derivatives |
| WO2005054170A1 (ja) * | 2003-12-05 | 2005-06-16 | Takara Bio Inc. | 治療剤 |
| US20060063828A1 (en) * | 2004-06-28 | 2006-03-23 | Weingarten M D | 1,2-Bis-(substituted-phenyl)-2-propen-1-ones and pharmaceutical compositions thereof |
| CN100336797C (zh) * | 2005-08-19 | 2007-09-12 | 浙江大学 | 四取代查耳酮衍生物及制备方法和用途 |
| GB0609386D0 (en) * | 2006-05-11 | 2006-06-21 | Active Botan Ltd | Treating drug resistant cancers |
| US9132117B2 (en) | 2013-06-17 | 2015-09-15 | Kgk Synergize, Inc | Compositions and methods for glycemic control of subjects with impaired fasting glucose |
| ES2540457B2 (es) * | 2013-06-19 | 2015-12-28 | Universidad De Sevilla | Procedimiento de obtención de extractos de hojas de Corema album y su aplicación terapéutica |
| KR101731159B1 (ko) | 2015-02-04 | 2017-04-28 | 계명대학교 산학협력단 | 2',4'-디하이드록시칼콘 화합물을 유효성분으로 포함하는 항진균용 조성물 |
| CZ307046B6 (cs) * | 2015-09-02 | 2017-12-13 | Univerzita PalackĂ©ho v Olomouci | Komplexy mědi s deriváty (E)-1-(2´-hydroxyfenyl)-3-fenylprop-2-en-1-onu a jejich použití jako léčiv v protinádorové terapii |
| CN111138264B (zh) * | 2019-11-29 | 2023-08-04 | 温州医科大学 | 一种丁香醛衍生物及其在制备抗妇科肿瘤药物中的应用 |
| CN113564103B (zh) * | 2021-05-17 | 2023-01-06 | 南京医科大学 | 4,4’-二甲氧基查耳酮在延缓卵母细胞体内外老化中的应用 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH593224A5 (cs) * | 1973-10-30 | 1977-11-30 | Taisho Pharmaceutical Co Ltd | |
| US5234951A (en) * | 1986-12-12 | 1993-08-10 | Tsumura Juntendo, Inc. | Anti-ulcer agent comprising chalcone derivative |
| HU203515B (en) * | 1986-12-12 | 1991-08-28 | Tsumura & Co | Process for producing new calcon derivatives and pharmaceutical compositions containing them as active components |
| AU7963691A (en) * | 1990-05-17 | 1991-12-10 | Baylor College Of Medicine | Growth inhibitors and methods of treating cancer and cell proliferative diseases |
| AU2393992A (en) * | 1991-07-24 | 1993-02-23 | Baylor College Of Medicine | Combination therapy using bioflavonoid compounds with anti-cancer drugs |
-
1994
- 1994-12-20 IT ITMI942568A patent/IT1271301B/it active IP Right Grant
-
1995
- 1995-12-04 PL PL95320787A patent/PL183772B1/pl not_active IP Right Cessation
- 1995-12-04 AT AT95941665T patent/ATE222756T1/de not_active IP Right Cessation
- 1995-12-04 CZ CZ19971869A patent/CZ288043B6/cs not_active IP Right Cessation
- 1995-12-04 SI SI9520139A patent/SI9520139B/sl not_active IP Right Cessation
- 1995-12-04 HU HU9702094A patent/HU225501B1/hu not_active IP Right Cessation
- 1995-12-04 WO PCT/EP1995/004770 patent/WO1996019209A1/en active IP Right Grant
- 1995-12-04 DE DE69527980T patent/DE69527980T2/de not_active Expired - Fee Related
- 1995-12-04 CA CA002208351A patent/CA2208351C/en not_active Expired - Fee Related
- 1995-12-04 RU RU97112461/14A patent/RU2181284C2/ru not_active IP Right Cessation
- 1995-12-04 DK DK95941665T patent/DK0800387T3/da active
- 1995-12-04 ES ES95941665T patent/ES2181806T3/es not_active Expired - Lifetime
- 1995-12-04 AU AU43019/96A patent/AU689357B2/en not_active Ceased
- 1995-12-04 EP EP95941665A patent/EP0800387B1/en not_active Expired - Lifetime
- 1995-12-04 CN CN95196940A patent/CN1087609C/zh not_active Expired - Fee Related
- 1995-12-04 FI FI972641A patent/FI972641L/fi unknown
- 1995-12-04 SK SK781-97A patent/SK282259B6/sk unknown
- 1995-12-04 US US08/849,767 patent/US5808137A/en not_active Expired - Fee Related
- 1995-12-04 PT PT95941665T patent/PT800387E/pt unknown
- 1995-12-04 KR KR1019970704130A patent/KR100264369B1/ko not_active Expired - Fee Related
-
1997
- 1997-06-19 NO NO972842A patent/NO307926B1/no unknown
-
2003
- 2003-12-26 JP JP2003434456A patent/JP2004131509A/ja active Pending
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