NO307926B1 - Chalkoner og estere derav med antiproliferativ aktivitet i uterus, ovarie- og brysttumorer - Google Patents

Chalkoner og estere derav med antiproliferativ aktivitet i uterus, ovarie- og brysttumorer

Info

Publication number
NO307926B1
NO307926B1 NO972842A NO972842A NO307926B1 NO 307926 B1 NO307926 B1 NO 307926B1 NO 972842 A NO972842 A NO 972842A NO 972842 A NO972842 A NO 972842A NO 307926 B1 NO307926 B1 NO 307926B1
Authority
NO
Norway
Prior art keywords
pct
uterus
chalcones
esters
antiproliferative activity
Prior art date
Application number
NO972842A
Other languages
English (en)
Other versions
NO972842D0 (no
NO972842L (no
Inventor
Ezio Bombardelli
Salvatore Mancuso
Franco Delle Monache
Original Assignee
Indena Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Indena Spa filed Critical Indena Spa
Publication of NO972842D0 publication Critical patent/NO972842D0/no
Publication of NO972842L publication Critical patent/NO972842L/no
Publication of NO307926B1 publication Critical patent/NO307926B1/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/12—Ketones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/017—Esters of hydroxy compounds having the esterified hydroxy group bound to a carbon atom of a six-membered aromatic ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicinal Preparation (AREA)
  • Steroid Compounds (AREA)
NO972842A 1994-12-20 1997-06-19 Chalkoner og estere derav med antiproliferativ aktivitet i uterus, ovarie- og brysttumorer NO307926B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ITMI942568A IT1271301B (it) 1994-12-20 1994-12-20 Calconi naturali e sintetici e loro esteri ad attivita' antiproliferativa nei tumori dell'utero,dell'ovaio e del seno e formulazioni che li contengono
PCT/EP1995/004770 WO1996019209A1 (en) 1994-12-20 1995-12-04 Chalcones and esters thereof with antiproliferative activity in uterus, ovary and breast tumours

Publications (3)

Publication Number Publication Date
NO972842D0 NO972842D0 (no) 1997-06-19
NO972842L NO972842L (no) 1997-06-19
NO307926B1 true NO307926B1 (no) 2000-06-19

Family

ID=11370023

Family Applications (1)

Application Number Title Priority Date Filing Date
NO972842A NO307926B1 (no) 1994-12-20 1997-06-19 Chalkoner og estere derav med antiproliferativ aktivitet i uterus, ovarie- og brysttumorer

Country Status (22)

Country Link
US (1) US5808137A (no)
EP (1) EP0800387B1 (no)
JP (1) JP2004131509A (no)
KR (1) KR100264369B1 (no)
CN (1) CN1087609C (no)
AT (1) ATE222756T1 (no)
AU (1) AU689357B2 (no)
CA (1) CA2208351C (no)
CZ (1) CZ288043B6 (no)
DE (1) DE69527980T2 (no)
DK (1) DK0800387T3 (no)
ES (1) ES2181806T3 (no)
FI (1) FI972641A (no)
HU (1) HU225501B1 (no)
IT (1) IT1271301B (no)
NO (1) NO307926B1 (no)
PL (1) PL183772B1 (no)
PT (1) PT800387E (no)
RU (1) RU2181284C2 (no)
SI (1) SI9520139B (no)
SK (1) SK282259B6 (no)
WO (1) WO1996019209A1 (no)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6423740B1 (en) 1997-06-19 2002-07-23 Indena S.P.A. Chalcones having antiproliferative activity
GB9712966D0 (en) * 1997-06-19 1997-08-27 Indena Spa Novel chalcones
US6239114B1 (en) * 1997-09-26 2001-05-29 Kgk Synergize Compositions and methods for treatment of neoplastic diseases with combinations of limonoids, flavonoids and tocotrienols
GB9920908D0 (en) 1999-09-03 1999-11-10 Indena Spa Chalcone coumarins
GB9920910D0 (en) 1999-09-03 1999-11-10 Indena Spa Novel chalcones
KR20030031500A (ko) 2000-06-20 2003-04-21 아테로제닉스, 인코포레이티드 1,3-비스-(치환된-페닐)-2-프로펜-1-온 및 ｖｃａｍ-1매개된 질환을 치료하기 위한 그의 용도
US6545007B2 (en) 2000-11-17 2003-04-08 Idenix (Cayman) Limited Methods for inhibiting the transmission of HIV using topically applied substituted 6-benzyl-4-oxopyrimidines
BR0215240A (pt) * 2001-12-19 2004-10-26 Atherogenics Inc Derivados de calcona e seu uso no tratamento de doenças
AU2003243594A1 (en) * 2002-06-13 2003-12-31 Johns Hopkins University Novel boronic chalcone derivatives and uses thereof
US20040181075A1 (en) * 2002-12-19 2004-09-16 Weingarten M. David Process of making chalcone derivatives
WO2005054170A1 (ja) * 2003-12-05 2005-06-16 Takara Bio Inc. 治療剤
WO2006004903A2 (en) * 2004-06-28 2006-01-12 Atherogenics, Inc. 1,2-bis-(substituted-phenyl)-2-propen-1-ones and pharmaceutical compositions thereof
CN100336797C (zh) * 2005-08-19 2007-09-12 浙江大学 四取代查耳酮衍生物及制备方法和用途
GB0609386D0 (en) * 2006-05-11 2006-06-21 Active Botan Ltd Treating drug resistant cancers
US9132117B2 (en) 2013-06-17 2015-09-15 Kgk Synergize, Inc Compositions and methods for glycemic control of subjects with impaired fasting glucose
ES2540457B2 (es) * 2013-06-19 2015-12-28 Universidad De Sevilla Procedimiento de obtención de extractos de hojas de Corema album y su aplicación terapéutica
KR101731159B1 (ko) 2015-02-04 2017-04-28 계명대학교 산학협력단 2',4'-디하이드록시칼콘 화합물을 유효성분으로 포함하는 항진균용 조성물
CZ307046B6 (cs) * 2015-09-02 2017-12-13 Univerzita PalackĂ©ho v Olomouci Komplexy mědi s deriváty (E)-1-(2´-hydroxyfenyl)-3-fenylprop-2-en-1-onu a jejich použití jako léčiv v protinádorové terapii
CN111138264B (zh) * 2019-11-29 2023-08-04 温州医科大学 一种丁香醛衍生物及其在制备抗妇科肿瘤药物中的应用
CN113564103B (zh) * 2021-05-17 2023-01-06 南京医科大学 4,4’-二甲氧基查耳酮在延缓卵母细胞体内外老化中的应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH593224A5 (no) * 1973-10-30 1977-11-30 Taisho Pharmaceutical Co Ltd
US5234951A (en) * 1986-12-12 1993-08-10 Tsumura Juntendo, Inc. Anti-ulcer agent comprising chalcone derivative
WO1988004288A1 (en) * 1986-12-12 1988-06-16 Tsumura Juntendo, Inc. Anti-ulcerous agent containing chalcone derivative as effective ingredient and novel chalcone derivatives
AU7963691A (en) * 1990-05-17 1991-12-10 Baylor College Of Medicine Growth inhibitors and methods of treating cancer and cell proliferative diseases
WO1993001824A1 (en) * 1991-07-24 1993-02-04 Baylor College Of Medicine Combination therapy using bioflavonoid compounds with anti-cancer drugs

Also Published As

Publication number Publication date
DE69527980T2 (de) 2003-05-28
EP0800387B1 (en) 2002-08-28
ITMI942568A1 (it) 1996-06-20
EP0800387A1 (en) 1997-10-15
FI972641A0 (fi) 1997-06-19
DE69527980D1 (de) 2002-10-02
DK0800387T3 (da) 2002-12-23
PL183772B1 (pl) 2002-07-31
CN1087609C (zh) 2002-07-17
CN1170362A (zh) 1998-01-14
FI972641A (fi) 1997-08-14
CZ288043B6 (cs) 2001-04-11
CA2208351A1 (en) 1996-06-27
PL320787A1 (en) 1997-10-27
US5808137A (en) 1998-09-15
IT1271301B (it) 1997-05-27
SI9520139B (sl) 1999-02-28
KR100264369B1 (ko) 2000-08-16
CA2208351C (en) 2002-06-25
HUT77438A (hu) 1998-04-28
CZ186997A3 (en) 1997-11-12
WO1996019209A1 (en) 1996-06-27
AU689357B2 (en) 1998-03-26
ES2181806T3 (es) 2003-03-01
AU4301996A (en) 1996-07-10
SK78197A3 (en) 1997-12-10
ATE222756T1 (de) 2002-09-15
SI9520139A (en) 1997-10-31
NO972842D0 (no) 1997-06-19
HU225501B1 (en) 2007-01-29
PT800387E (pt) 2002-12-31
JP2004131509A (ja) 2004-04-30
NO972842L (no) 1997-06-19
RU2181284C2 (ru) 2002-04-20
SK282259B6 (sk) 2001-12-03
ITMI942568A0 (it) 1994-12-20

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