FI972074A0 - Akrylamidderivat och foerfarande foer framstaellning daerav - Google Patents
Akrylamidderivat och foerfarande foer framstaellning daeravInfo
- Publication number
- FI972074A0 FI972074A0 FI972074A FI972074A FI972074A0 FI 972074 A0 FI972074 A0 FI 972074A0 FI 972074 A FI972074 A FI 972074A FI 972074 A FI972074 A FI 972074A FI 972074 A0 FI972074 A0 FI 972074A0
- Authority
- FI
- Finland
- Prior art keywords
- acrylamide derivatives
- acrylamides
- fertilizers
- production
- general formula
- Prior art date
Links
- 150000003926 acrylamides Chemical class 0.000 title abstract 4
- 239000003337 fertilizer Substances 0.000 title 1
- 206010028980 Neoplasm Diseases 0.000 abstract 2
- 201000011510 cancer Diseases 0.000 abstract 1
- 231100001231 less toxic Toxicity 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Indole Compounds (AREA)
- Fertilizers (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP29527494 | 1994-11-29 | ||
PCT/JP1995/002413 WO1996016965A1 (fr) | 1994-11-29 | 1995-11-28 | Derives d'acrylamide et leur procede de production |
Publications (1)
Publication Number | Publication Date |
---|---|
FI972074A0 true FI972074A0 (fi) | 1997-05-14 |
Family
ID=17818480
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FI972074A FI972074A0 (fi) | 1994-11-29 | 1997-05-14 | Akrylamidderivat och foerfarande foer framstaellning daerav |
Country Status (12)
Country | Link |
---|---|
US (1) | US5786486A (fr) |
EP (1) | EP0799827B1 (fr) |
KR (1) | KR100395083B1 (fr) |
CN (1) | CN1051552C (fr) |
AT (1) | ATE266663T1 (fr) |
AU (1) | AU693283B2 (fr) |
CA (1) | CA2205872A1 (fr) |
DE (1) | DE69533043T2 (fr) |
FI (1) | FI972074A0 (fr) |
HU (1) | HUT77654A (fr) |
MX (1) | MX9703917A (fr) |
WO (1) | WO1996016965A1 (fr) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1231440C (zh) | 1998-01-28 | 2005-12-14 | 盐野义制药株式会社 | 新的三环化合物 |
MXPA03011094A (es) * | 2001-05-31 | 2004-12-06 | Medarex Inc | Citotoxinas, profarmacos, ligadores, y estabilizadores utiles para ello. |
EP1747021B1 (fr) * | 2004-05-19 | 2015-09-09 | E. R. Squibb & Sons, L.L.C. | Bras de liaison chimiques et conjugues associes |
RU2402548C2 (ru) * | 2004-05-19 | 2010-10-27 | Медарекс, Инк. | Химические линкеры и их конъюгаты |
MX2007009878A (es) * | 2005-02-18 | 2007-10-03 | Medarex Inc | Anticuerpos monoclonales para antigeno de membrana especifica para prostata (amep). |
US7714016B2 (en) * | 2005-04-08 | 2010-05-11 | Medarex, Inc. | Cytotoxic compounds and conjugates with cleavable substrates |
BRPI0619331A2 (pt) | 2005-10-26 | 2011-09-27 | Medarex Inc | método para fazer um composto para preparar um análogo de cbi cc-1065, método para preparar um análogo de cbi cc-1065 e composto |
WO2007059404A2 (fr) | 2005-11-10 | 2007-05-24 | Medarex, Inc. | Composes et conjugues cytotoxiques |
TWI412367B (zh) | 2006-12-28 | 2013-10-21 | Medarex Llc | 化學鏈接劑與可裂解基質以及其之綴合物 |
JP2010519310A (ja) | 2007-02-21 | 2010-06-03 | メダレックス インコーポレイテッド | 単一のアミノ酸を有する化学リンカーおよびその複合体 |
WO2014080251A1 (fr) | 2012-11-24 | 2014-05-30 | Hangzhou Dac Biotech Co., Ltd. | Lieurs hydrophiles et leurs utilisations pour la conjugaison de médicaments à des molécules se liant aux cellules |
DK3122757T3 (da) | 2014-02-28 | 2023-10-09 | Hangzhou Dac Biotech Co Ltd | Ladede linkere og anvendelse deraf til konjugering |
JP6759326B2 (ja) | 2015-07-12 | 2020-09-23 | ハンジョウ ディーエーシー バイオテック シーオー.,エルティディ.Hangzhou Dac Biotech Co.,Ltd. | 細胞結合分子の共役のための架橋連結体 |
US9839687B2 (en) | 2015-07-15 | 2017-12-12 | Suzhou M-Conj Biotech Co., Ltd. | Acetylenedicarboxyl linkers and their uses in specific conjugation of a cell-binding molecule |
AU2016429272A1 (en) | 2016-11-14 | 2019-05-02 | Hangzhou Dac Biotech Co., Ltd. | Conjugation linkers, cell binding molecule-drug conjugates containing the likers, methods of making and uses such conjugates with the linkers |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA1238907A (fr) * | 1984-02-21 | 1988-07-05 | Robert C. Kelly | 1,2,8,8a-tetrahydrocyclopropa¬c|pyrrolo (3,2-e)-indol-4(5h)-ones et composes apparentes |
DE3750612T2 (de) * | 1986-12-19 | 1995-03-02 | Upjohn Co | Cc-1065 analoge. |
US5258383A (en) * | 1991-06-28 | 1993-11-02 | Kyowa Hakko Kogyo Co., Ltd. | DC-89 derivatives |
JP2502005B2 (ja) | 1992-04-27 | 1996-05-29 | オンキヨー株式会社 | バイオフィ―ドバックシステム |
JP3514490B2 (ja) * | 1992-08-21 | 2004-03-31 | 杏林製薬株式会社 | トリフルオロメチルピロロインドールカルボン酸エステル誘導体及びその製造方法 |
-
1995
- 1995-11-28 CA CA002205872A patent/CA2205872A1/fr not_active Abandoned
- 1995-11-28 CN CN95197472A patent/CN1051552C/zh not_active Expired - Fee Related
- 1995-11-28 KR KR1019970703468A patent/KR100395083B1/ko not_active IP Right Cessation
- 1995-11-28 WO PCT/JP1995/002413 patent/WO1996016965A1/fr active IP Right Grant
- 1995-11-28 AU AU39370/95A patent/AU693283B2/en not_active Ceased
- 1995-11-28 EP EP95937194A patent/EP0799827B1/fr not_active Expired - Lifetime
- 1995-11-28 AT AT95937194T patent/ATE266663T1/de not_active IP Right Cessation
- 1995-11-28 HU HU9800067A patent/HUT77654A/hu not_active Application Discontinuation
- 1995-11-28 US US08/849,160 patent/US5786486A/en not_active Expired - Fee Related
- 1995-11-28 MX MX9703917A patent/MX9703917A/es not_active IP Right Cessation
- 1995-11-28 DE DE69533043T patent/DE69533043T2/de not_active Expired - Fee Related
-
1997
- 1997-05-14 FI FI972074A patent/FI972074A0/fi not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
KR100395083B1 (ko) | 2004-02-05 |
EP0799827B1 (fr) | 2004-05-12 |
DE69533043T2 (de) | 2005-04-07 |
DE69533043D1 (de) | 2004-06-17 |
WO1996016965A1 (fr) | 1996-06-06 |
ATE266663T1 (de) | 2004-05-15 |
CN1051552C (zh) | 2000-04-19 |
HUT77654A (hu) | 1998-07-28 |
AU693283B2 (en) | 1998-06-25 |
EP0799827A1 (fr) | 1997-10-08 |
CA2205872A1 (fr) | 1996-06-06 |
EP0799827A4 (fr) | 1998-01-28 |
MX9703917A (es) | 1998-05-31 |
US5786486A (en) | 1998-07-28 |
AU3937095A (en) | 1996-06-19 |
CN1174553A (zh) | 1998-02-25 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FA | Application withdrawn |