FI970258A0 - Uusi menetelmä biologisesti aktiivisen proteiinin valmistamiseksi - Google Patents
Uusi menetelmä biologisesti aktiivisen proteiinin valmistamiseksiInfo
- Publication number
- FI970258A0 FI970258A0 FI970258A FI970258A FI970258A0 FI 970258 A0 FI970258 A0 FI 970258A0 FI 970258 A FI970258 A FI 970258A FI 970258 A FI970258 A FI 970258A FI 970258 A0 FI970258 A0 FI 970258A0
- Authority
- FI
- Finland
- Prior art keywords
- biologically active
- new method
- active protein
- producing biologically
- beta
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/495—Transforming growth factor [TGF]
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Toxicology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP94810439 | 1994-07-25 | ||
EP94810439 | 1994-07-25 | ||
EP9502719 | 1995-07-12 | ||
PCT/EP1995/002719 WO1996003433A1 (en) | 1994-07-25 | 1995-07-12 | New process for the production of biologically active protein |
Publications (3)
Publication Number | Publication Date |
---|---|
FI970258A0 true FI970258A0 (fi) | 1997-01-22 |
FI970258A FI970258A (fi) | 1997-01-22 |
FI118385B FI118385B (fi) | 2007-10-31 |
Family
ID=8218293
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FI970258A FI118385B (fi) | 1994-07-25 | 1997-01-22 | Uusi menetelmä biologisesti aktiivisen proteiinin valmistamiseksi |
Country Status (19)
Country | Link |
---|---|
US (1) | US7057016B2 (fi) |
EP (1) | EP0779896B1 (fi) |
JP (2) | JPH11505404A (fi) |
KR (1) | KR100394532B1 (fi) |
AT (1) | ATE207934T1 (fi) |
AU (1) | AU699879B2 (fi) |
CA (1) | CA2194578A1 (fi) |
DE (1) | DE69523611T2 (fi) |
DK (1) | DK0779896T3 (fi) |
ES (1) | ES2166402T3 (fi) |
FI (1) | FI118385B (fi) |
HU (1) | HU222829B1 (fi) |
IL (1) | IL114702A (fi) |
NO (1) | NO317730B1 (fi) |
NZ (1) | NZ290374A (fi) |
PT (1) | PT779896E (fi) |
TW (1) | TW517059B (fi) |
WO (1) | WO1996003433A1 (fi) |
ZA (1) | ZA956139B (fi) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6084076A (en) * | 1995-12-21 | 2000-07-04 | Ajinomoto Co., Inc. | Method of refolding human activin A |
DE10026713A1 (de) * | 2000-05-30 | 2001-12-06 | Walter Sebald | Mutein einer Kette eines Proteins aus der Superfamilie des Wachstumsfaktors TGF-beta |
US20030134292A1 (en) * | 2001-10-30 | 2003-07-17 | Farchaus Joseph W. | Thermostable DNA polymerases and methods of making same |
FR2871061B1 (fr) * | 2004-06-04 | 2007-08-10 | Coletica Sa | Principe actif capable d'induire la transformation du tgbf- latent inactif en tgfb actif |
US7572474B2 (en) | 2005-06-01 | 2009-08-11 | Mead Johnson Nutrition Company | Method for simulating the functional attributes of human milk oligosaccharides in formula-fed infants |
US8075934B2 (en) * | 2008-10-24 | 2011-12-13 | Mead Johnson Nutrition Company | Nutritional composition with improved digestibility |
US8480797B2 (en) | 2005-09-12 | 2013-07-09 | Abela Pharmaceuticals, Inc. | Activated carbon systems for facilitating use of dimethyl sulfoxide (DMSO) by removal of same, related compounds, or associated odors |
WO2007033082A2 (en) | 2005-09-12 | 2007-03-22 | Abela Pharmaceuticals, Inc. | Compositions comprising dimethyl sulfoxide (dmso) |
WO2007033083A2 (en) | 2005-09-12 | 2007-03-22 | Abela Pharmaceuticals, Inc. | Systems for removing dimethyl sulfoxide (dmso) or related compounds, or odors associated with same |
WO2007033180A1 (en) | 2005-09-12 | 2007-03-22 | Abela Pharmaceuticals, Inc. | Materials for facilitating administration of dimethyl sulfoxide (dmso) and related compounds |
GB0604966D0 (en) * | 2006-03-11 | 2006-04-19 | Renovo Ltd | Medicaments and proteins |
US8986769B2 (en) * | 2008-10-24 | 2015-03-24 | Mead Johnson Nutrition Company | Methods for preserving endogenous TGF-β |
BRPI0921494A2 (pt) | 2008-11-03 | 2018-10-30 | Prad Reasearch And Development Ltd | método de planejamento de uma operação de amostragem para uma formação subterrãnea, método de contolar uma operação de amostragem de formação subterrânea, método de controlar uma operação de perfuração para uma formação subterrãnea, e método de realizar uma amostragem durante a operação de perfuração. |
CA2779111C (en) | 2009-10-30 | 2019-08-13 | Abela Pharmaceuticals, Inc. | Dimethyl sulfoxide (dmso) and methylsulfonylmethane (msm) formulations to treat osteoarthritis |
US10647777B2 (en) * | 2014-05-28 | 2020-05-12 | Genzyme Corporation | Methods of controlling the formation of disulfide bonds in protein solutions |
JP2016183118A (ja) * | 2015-03-25 | 2016-10-20 | 東ソー株式会社 | 増殖因子前駆体のリフォールディング方法 |
NZ746109A (en) | 2016-12-30 | 2022-12-23 | Biogend Therapeutics Co Ltd | Recombinant polypeptides and nucleic acid molecules, compositions, and methods of making and uses thereof |
WO2023064747A1 (en) * | 2021-10-11 | 2023-04-20 | University Of Pittsburgh - Of The Commonwealth System Of Higher Education | Engineered tgf-beta monomers and methods of use |
GB2616476A (en) * | 2022-03-11 | 2023-09-13 | Multus Biotechnology Ltd | Recombinant transforming growth factor beta 3 in yeast |
Family Cites Families (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3168691D1 (en) * | 1980-11-07 | 1985-03-14 | Technicon Instr | Immunoassay of proteins |
GR79124B (fi) | 1982-12-22 | 1984-10-02 | Genentech Inc | |
US4620948A (en) | 1982-12-22 | 1986-11-04 | Genentech, Inc. | Purification and activity assurance of precipitated heterologous proteins |
EP0154434B1 (en) | 1984-02-17 | 1993-01-27 | Genentech, Inc. | Human transforming growth factor and precursor or fragment thereof, cells, dna, vectors and methods for their production, compositions and products containing them, and related antibodies and diagnostic methods |
US4572798A (en) | 1984-12-06 | 1986-02-25 | Cetus Corporation | Method for promoting disulfide bond formation in recombinant proteins |
US4731440A (en) | 1985-02-22 | 1988-03-15 | Monsanto Company | Method of somatotropin solubilization using dimethylsulfone and naturation |
IL78197A (en) | 1985-03-22 | 1991-07-18 | Genentech Inc | Nucleic acid encoding tgf-beta and its uses |
GB8508340D0 (en) | 1985-03-29 | 1985-05-09 | Creighton T E | Production of protein |
EP0208539A3 (en) | 1985-07-11 | 1988-08-03 | Repligen Corporation | Folding disulfide-cross-linkable proteins |
US5453363A (en) | 1985-10-23 | 1995-09-26 | Boehringer Mannheim Gmbh | Process for the activation of t-PA or Ing after genetic expression in prokaryotes |
JPH0759598B2 (ja) * | 1986-02-14 | 1995-06-28 | 藤沢薬品工業株式会社 | ヒトインスリン様成長因子▲i▼の製造法 |
NZ222168A (en) | 1986-10-20 | 1991-05-28 | Oncogene Science Inc | Tumour growth inhibiting protein related to tgf-#b#1 and tgf-#b#2, preparation by genetic engineering methods, antibodies and pharmaceutical compositions |
KR890700031A (ko) | 1986-11-17 | 1989-03-02 | 예안 크라메르 한스 루돌프 하우스 | 신규한 t-세포 억압 인자의 제조 및 그것의 용도 |
FI100106B (fi) | 1986-12-05 | 1997-09-30 | Novartis Ag | Menetelmä plasminogeenin yksisäikeisen yhdistelmäaktivaattorin valmist amiseksi |
US4931548A (en) | 1987-01-30 | 1990-06-05 | Techne Corporation | Heterodimer form of transforming growth factor-beta |
IL86090A (en) | 1987-04-16 | 1993-03-15 | Cetus Oncology Corp | Production of purified, biologically active, bacterially produced recombinant human csf-1 |
US5162507A (en) | 1987-05-11 | 1992-11-10 | Cetus Corporation | Process for recovering purified, oxidized, renatured recombinant interleukin-2 from microorganisms |
DE3855986T2 (de) | 1987-05-11 | 1998-02-05 | Chiron Corp | Prozess zur gewinnung von gereinigtem, oxidiertem, renaturiertem, rekombinantem interleukin-2 aus mikroorganismen |
EP0293785A3 (en) * | 1987-05-29 | 1990-05-02 | Oncogen Limited Partnership | Cloning and expression of simian transforming growth factor-ss1 |
US4985544A (en) | 1987-08-04 | 1991-01-15 | Kyowa Hakko Kogyo Co., Ltd. | Process for renaturing fish growth hormone |
US5061786A (en) * | 1989-05-25 | 1991-10-29 | Genentech, Inc. | Biologically active polypeptides based on transforming growth factor-β |
GB8927546D0 (en) * | 1989-12-06 | 1990-02-07 | Ciba Geigy | Process for the production of biologically active tgf-beta |
US5843463A (en) * | 1990-12-21 | 1998-12-01 | Antexbiologics, Inc. | Adhesin-oligosaccharide conjugate vaccine for Haemophilus influenzae |
US5144006A (en) * | 1991-06-13 | 1992-09-01 | The Rockefeller University | Oxidative folding of peptide and protein substrates using hydrocarbon sulfoxides |
AU2738392A (en) * | 1991-11-11 | 1993-05-13 | Ciba-Geigy Ag | Novel hybrid transforming growth factors |
US5407810A (en) * | 1993-08-20 | 1995-04-18 | Genentech, Inc. | Aqueous multiple-phase isolation of polypeptide |
TW440566B (en) * | 1994-07-25 | 2001-06-16 | Novartis Ag | Novel process for the production of biologically active dimeric protein |
-
1995
- 1995-07-11 TW TW084107189A patent/TW517059B/zh not_active IP Right Cessation
- 1995-07-12 CA CA002194578A patent/CA2194578A1/en not_active Abandoned
- 1995-07-12 ES ES95926858T patent/ES2166402T3/es not_active Expired - Lifetime
- 1995-07-12 WO PCT/EP1995/002719 patent/WO1996003433A1/en active IP Right Grant
- 1995-07-12 HU HU9700211A patent/HU222829B1/hu not_active IP Right Cessation
- 1995-07-12 JP JP8505401A patent/JPH11505404A/ja not_active Withdrawn
- 1995-07-12 KR KR1019970700477A patent/KR100394532B1/ko not_active IP Right Cessation
- 1995-07-12 DE DE69523611T patent/DE69523611T2/de not_active Expired - Lifetime
- 1995-07-12 DK DK95926858T patent/DK0779896T3/da active
- 1995-07-12 EP EP95926858A patent/EP0779896B1/en not_active Expired - Lifetime
- 1995-07-12 AU AU31096/95A patent/AU699879B2/en not_active Ceased
- 1995-07-12 PT PT95926858T patent/PT779896E/pt unknown
- 1995-07-12 AT AT95926858T patent/ATE207934T1/de not_active IP Right Cessation
- 1995-07-12 NZ NZ290374A patent/NZ290374A/en not_active IP Right Cessation
- 1995-07-24 ZA ZA956139A patent/ZA956139B/xx unknown
- 1995-07-24 IL IL11470295A patent/IL114702A/xx not_active IP Right Cessation
-
1997
- 1997-01-22 FI FI970258A patent/FI118385B/fi active IP Right Grant
- 1997-01-24 NO NO19970326A patent/NO317730B1/no not_active IP Right Cessation
-
2001
- 2001-03-20 US US09/813,271 patent/US7057016B2/en not_active Expired - Fee Related
-
2006
- 2006-11-09 JP JP2006304238A patent/JP4354980B2/ja not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
NO970326L (no) | 1997-01-24 |
NZ290374A (en) | 1998-07-28 |
IL114702A (en) | 2005-03-20 |
TW517059B (en) | 2003-01-11 |
JP4354980B2 (ja) | 2009-10-28 |
ES2166402T3 (es) | 2002-04-16 |
HU222829B1 (hu) | 2003-11-28 |
AU3109695A (en) | 1996-02-22 |
NO970326D0 (no) | 1997-01-24 |
WO1996003433A1 (en) | 1996-02-08 |
US7057016B2 (en) | 2006-06-06 |
ATE207934T1 (de) | 2001-11-15 |
PT779896E (pt) | 2002-03-28 |
JPH11505404A (ja) | 1999-05-21 |
HUT76667A (en) | 1997-10-28 |
DK0779896T3 (da) | 2002-02-18 |
NO317730B1 (no) | 2004-12-13 |
EP0779896A1 (en) | 1997-06-25 |
ZA956139B (en) | 1996-03-07 |
AU699879B2 (en) | 1998-12-17 |
US20020115834A1 (en) | 2002-08-22 |
IL114702A0 (en) | 1995-11-27 |
DE69523611D1 (de) | 2001-12-06 |
CA2194578A1 (en) | 1996-02-08 |
DE69523611T2 (de) | 2002-06-20 |
FI118385B (fi) | 2007-10-31 |
KR100394532B1 (ko) | 2003-10-22 |
FI970258A (fi) | 1997-01-22 |
EP0779896B1 (en) | 2001-10-31 |
JP2007082554A (ja) | 2007-04-05 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
FI970258A (fi) | Uusi menetelmä biologisesti aktiivisen proteiinin valmistamiseksi | |
NO970325D0 (no) | Fremgangsmåte for fremstilling av biologisk aktivt dimerisk protein | |
ATE410441T1 (de) | Zusammensetzungen und methoden zur behandlung von infektionen unter verwendung von indolicidinanalogen | |
NZ237666A (en) | Hiv envelope (env) polypeptides, antibodies and compositions for treating aids | |
PT92278A (pt) | Processo para a preparacao de proteinas de ligacao de factor de crescimento semelhante a insulina | |
FI914911A (fi) | Ternimaitofraktio, menetelmä sen valmistamiseksi ja sen käyttö kasvualustojen täydennysaineena | |
DK0764209T3 (da) | Albuminekspression i gær | |
IT8421436A1 (it) | Un plasmide ricombinante, un microorganismo trasformante, un segmento di polideossiribonucleotide, un procedimento per produrre una proteina biologicamente attiva e la proteina così prodotta | |
BG103219A (en) | Benzamidine derivatives and their application as medicamentous forms with ltb-4-antagonist effect | |
FI895935A0 (fi) | Menetelmä kimeerisen transformoivan beta-kasvutekijän valmistamiseksi | |
MX9700657A (es) | Nuevo proceso para la produccion de proteina biologicamente activa. | |
ATE185349T1 (de) | Verfahren zur herstellung von dolastatin 15 und deren zwischenprodukten | |
MX9700656A (es) | Proceso novedoso para la produccion de proteina dimerica biologicamente activa. | |
PL355852A1 (en) | Fragments of virus protein vp2 or 3 of the polyoma virus, used for transporting active ingredients | |
ES2049021T3 (es) | Metodo de recuperar la proteina epi purificada a partir de una solucion, especialmente una solucion de fermentacion. | |
DE3783425D1 (de) | Mikroorganismen, die fremdproteinenthaltende pili tragen, isolierte pili, verfahren zur ausscheidung von proteinen in verwendung dieser pili und deren nutzen. | |
FI970230A (fi) | Menetelmä proteiinien, kuten yhdistelmä-DNA-hirudiinin tai -epidermaalisen kasvutekijän laskostamiseksi | |
ES2004734A6 (es) | Procedimiento de obtencion de conjugados biologicamente activos de metaloproteina-albumina o metaloproteina-albumina-anticuerpos |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
GB | Transfer or assigment of application |
Owner name: NOVARTIS AG |
|
FG | Patent granted |
Ref document number: 118385 Country of ref document: FI |