FI960977A - Bakteeriperäiset eksportoidut proteiinit ja niihin perustuvat asellulaariset rokotteet - Google Patents

Bakteeriperäiset eksportoidut proteiinit ja niihin perustuvat asellulaariset rokotteet Download PDF

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Publication number
FI960977A
FI960977A FI960977A FI960977A FI960977A FI 960977 A FI960977 A FI 960977A FI 960977 A FI960977 A FI 960977A FI 960977 A FI960977 A FI 960977A FI 960977 A FI960977 A FI 960977A
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FI
Finland
Prior art keywords
pct
proteins
noncellular
exported proteins
bacterial origin
Prior art date
Application number
FI960977A
Other languages
English (en)
Swedish (sv)
Other versions
FI960977A0 (fi
Inventor
Robert H Masure
Barbara J Pearce
Elaine Tuomanen
Original Assignee
Univ Rockefeller
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Rockefeller filed Critical Univ Rockefeller
Publication of FI960977A0 publication Critical patent/FI960977A0/fi
Publication of FI960977A publication Critical patent/FI960977A/fi

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004Oxidoreductases (1.)
    • C12N9/0008Oxidoreductases (1.) acting on the aldehyde or oxo group of donors (1.2)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/315Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
    • C07K14/3156Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci from Streptococcus pneumoniae (Pneumococcus)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52Genes encoding for enzymes or proenzymes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y102/00Oxidoreductases acting on the aldehyde or oxo group of donors (1.2)
    • C12Y102/03Oxidoreductases acting on the aldehyde or oxo group of donors (1.2) with oxygen as acceptor (1.2.3)
    • C12Y102/03003Pyruvate oxidase (1.2.3.3)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/01Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02Fusion polypeptide containing a localisation/targetting motif containing a signal sequence

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pulmonology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Plant Pathology (AREA)
  • Communicable Diseases (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
FI960977A 1993-09-01 1996-03-01 Bakteeriperäiset eksportoidut proteiinit ja niihin perustuvat asellulaariset rokotteet FI960977A (fi)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US11654193A 1993-09-01 1993-09-01
US08/245,511 US5928900A (en) 1993-09-01 1994-05-18 Bacterial exported proteins and acellular vaccines based thereon
PCT/US1994/009942 WO1995006732A2 (en) 1993-09-01 1994-09-01 Bacterial exported proteins and acellular vaccines based thereon

Publications (2)

Publication Number Publication Date
FI960977A0 FI960977A0 (fi) 1996-03-01
FI960977A true FI960977A (fi) 1996-04-30

Family

ID=26814346

Family Applications (1)

Application Number Title Priority Date Filing Date
FI960977A FI960977A (fi) 1993-09-01 1996-03-01 Bakteeriperäiset eksportoidut proteiinit ja niihin perustuvat asellulaariset rokotteet

Country Status (14)

Country Link
US (2) US5928900A (fi)
EP (1) EP0721506B1 (fi)
JP (1) JP3722834B2 (fi)
AT (1) ATE332376T1 (fi)
AU (1) AU709405B2 (fi)
CA (1) CA2170726A1 (fi)
DE (1) DE69434784T2 (fi)
DK (1) DK0721506T3 (fi)
ES (1) ES2267096T3 (fi)
FI (1) FI960977A (fi)
NO (1) NO321826B1 (fi)
NZ (1) NZ273497A (fi)
PT (1) PT721506E (fi)
WO (1) WO1995006732A2 (fi)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995031548A1 (en) * 1994-05-16 1995-11-23 The Uab Research Foundation Streptococcus pneumoniae capsular polysaccharide genes and flanking regions
US5834278A (en) * 1996-05-01 1998-11-10 The Rockefeller University Bacterial peptide methionine sulfoxide reductase an adhesion-associated protein, and antibiotic therapies based thereon
US6245335B1 (en) 1996-05-01 2001-06-12 The Rockefeller University Choline binding proteins for anti-pneumococcal vaccines
US6165989A (en) * 1996-05-14 2000-12-26 Smithkline Beecham Corporation Era of Streptococcus pneumoniae
JP2000514308A (ja) * 1996-08-16 2000-10-31 スミスクライン・ビーチャム・コーポレイション 新規原核生物ポリヌクレオチド、ポリペプチドおよびそれらの使用
US5882871A (en) * 1996-09-24 1999-03-16 Smithkline Beecham Corporation Saliva binding protein
US5882896A (en) 1996-09-24 1999-03-16 Smithkline Beecham Corporation M protein
US5928895A (en) * 1996-09-24 1999-07-27 Smithkline Beecham Corporation IgA Fc binding protein
EP0941335A2 (en) 1996-10-31 1999-09-15 Human Genome Sciences Streptococcus pneumoniae polynucleotides and sequences
US6291654B1 (en) 1996-11-12 2001-09-18 Regents Of The University Of Minnesota Method for isolating a C3 binding protein of streptococcus pneumoniae
US20040242522A1 (en) * 1997-02-14 2004-12-02 Volkin David B. Polynucleotide vaccine formulations
US6676943B1 (en) 1997-04-24 2004-01-13 Regents Of The University Of Minnesota Human complement C3-degrading protein from Streptococcus pneumoniae
DK1098980T3 (da) 1998-07-22 2014-09-29 Stichting Dienst Landbouwkundi Streptococcus suis-vacciner og diagnostiske tests
US20030134407A1 (en) 1998-07-27 2003-07-17 Le Page Richard William Falla Nucleic acids and proteins from Streptococcus pneumoniae
US6936252B2 (en) 1998-07-27 2005-08-30 Microbial Technics Limited Streptococcus pneumoniae proteins and nucleic acid molecules
EP1790730A3 (en) * 1998-07-27 2007-09-12 Sanofi Pasteur Limited Streptococcus pneumoniae proteins and nucleic acid molecules
CA2337102A1 (en) * 1998-07-27 2000-02-10 Richard William Falla Le Page Nucleic acids and proteins from group b streptococcus
EP1624064A3 (en) * 1998-07-27 2006-05-10 Microbial Technics Limited Nucleic acids and proteins from streptococcus pneumoniae
EP2053126A1 (en) * 1998-07-27 2009-04-29 Sanofi Pasteur Limited Streptococcus pneumoniae proteins and nucleic acid molecules
EP1801218A3 (en) * 1998-07-27 2007-10-10 Sanofi Pasteur Limited Nucleic acids and proteins from streptococcus pneumoniae
US7098182B2 (en) 1998-07-27 2006-08-29 Microbial Technics Limited Nucleic acids and proteins from group B streptococcus
JP2002521058A (ja) * 1998-07-27 2002-07-16 マイクロビアル テクニクス リミティッド 肺炎連鎖球菌由来の核酸及びタンパク質
JP4689044B2 (ja) 1998-12-21 2011-05-25 メディミューン,インコーポレーテッド ワクチン用の肺炎連鎖球菌タンパク質と免疫原断片
GB9921125D0 (en) * 1999-09-07 1999-11-10 Microbial Technics Limited Proteins
IL151348A0 (en) 2000-04-13 2003-04-10 Univ Rockefeller Enhancement of antibody-mediated immune responses
EP1205552A1 (en) 2000-11-09 2002-05-15 ID-Lelystad, Instituut voor Dierhouderij en Diergezondheid B.V. Virulence of streptococci, involving ORFs from Streptococcus suis
JP4275413B2 (ja) * 2001-02-02 2009-06-10 イーデー−レーリスタット,インスティチュート フォール ディールハウデレイ エン ディールゲゾントヘイト ベー.フェー. ストレプトコッカス・スイスの環境的に調節された遺伝子
WO2003012071A2 (en) * 2001-08-03 2003-02-13 Elitra Pharmaceuticals, Inc. Nucleic acids of aspergillus fumigatus encoding industrial enzymes and methods of use
NO20026286D0 (no) * 2002-12-30 2002-12-30 Amersham Health As Nye peptider
EP2023143A1 (en) * 2007-08-06 2009-02-11 Boehringer Ingelheim Vetmedica Gmbh Immunogenic streptococcus proteins
EP2897638A1 (en) 2012-09-24 2015-07-29 Montana State University-Bozeman Recombinant lactococcus lactis expressing escherichia coli colonization factor antigen i (cfa/i) fimbriae and their methods of use

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0274425B1 (en) * 1987-01-06 1993-12-15 Asahi Kasei Kogyo Kabushiki Kaisha Pyruvate oxidase, its preparation and use
JP3237842B2 (ja) * 1988-12-16 2001-12-10 オランダ国 ニューモリシンミュータント及びそれから製造されたニューモコッカルワクチン
DK0571538T5 (da) * 1991-02-15 2002-03-04 Uab Research Foundation Strukturgen for pneumokokprotein
AU3065892A (en) * 1991-11-14 1993-06-15 Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The Pneumococcal fimbrial protein a vaccines
CA2127550A1 (en) * 1992-01-08 1993-07-22 Vincent Fischetti Multifunctional surface protein of streptococci

Also Published As

Publication number Publication date
FI960977A0 (fi) 1996-03-01
EP0721506A1 (en) 1996-07-17
DE69434784D1 (de) 2006-08-17
NO960839D0 (no) 1996-02-29
US5928900A (en) 1999-07-27
WO1995006732A2 (en) 1995-03-09
DK0721506T3 (da) 2006-10-30
CA2170726A1 (en) 1995-03-09
NO960839L (no) 1996-04-19
PT721506E (pt) 2006-10-31
JPH09504686A (ja) 1997-05-13
AU709405B2 (en) 1999-08-26
DE69434784T2 (de) 2007-06-14
ES2267096T3 (es) 2007-03-01
EP0721506B1 (en) 2006-07-05
WO1995006732A3 (en) 1995-06-01
NO321826B1 (no) 2006-07-10
AU7680994A (en) 1995-03-22
NZ273497A (en) 1998-03-25
ATE332376T1 (de) 2006-07-15
US5981229A (en) 1999-11-09
JP3722834B2 (ja) 2005-11-30

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