AU1915995A - Active immunization using a siderophore receptor protein - Google Patents

Active immunization using a siderophore receptor protein

Info

Publication number
AU1915995A
AU1915995A AU19159/95A AU1915995A AU1915995A AU 1915995 A AU1915995 A AU 1915995A AU 19159/95 A AU19159/95 A AU 19159/95A AU 1915995 A AU1915995 A AU 1915995A AU 1915995 A AU1915995 A AU 1915995A
Authority
AU
Australia
Prior art keywords
gram
vaccine
siderophore receptor
negative bacteria
receptor protein
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU19159/95A
Inventor
Beth A Carlson
Daryll A Emery
Richard Huisinga
Darren E Straub
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Willmar Poultry Co Inc
Original Assignee
Willmar Poultry Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/385,273 external-priority patent/US5830479A/en
Application filed by Willmar Poultry Co Inc filed Critical Willmar Poultry Co Inc
Publication of AU1915995A publication Critical patent/AU1915995A/en
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/24Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
    • C07K14/245Escherichia (G)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/025Enterobacteriales, e.g. Enterobacter
    • A61K39/0258Escherichia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/025Enterobacteriales, e.g. Enterobacter
    • A61K39/0275Salmonella
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/102Pasteurellales, e.g. Actinobacillus, Pasteurella; Haemophilus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911Bacteria
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911Bacteria
    • G01N33/56916Enterobacteria, e.g. shigella, salmonella, klebsiella, serratia
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S424/00Drug, bio-affecting and body treating compositions
    • Y10S424/823Bacterial vaccine for bovine species, e.g. cattle
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S424/00Drug, bio-affecting and body treating compositions
    • Y10S424/824Bacterial vaccine for ovine species, e.g. sheep
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S424/00Drug, bio-affecting and body treating compositions
    • Y10S424/825Bacterial vaccine for porcine species, e.g. swine
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S424/00Drug, bio-affecting and body treating compositions
    • Y10S424/826Bacterial vaccine for avian species, e.g. poultry or other birds
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/82Proteins from microorganisms
    • Y10S530/825Bacteria

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Biochemistry (AREA)
  • Organic Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)

Abstract

The invention provides a vaccine for immunizing poultry and other animals against infection by a gram-negative bacteria, and a method of immunizing an animal using the vaccine. The vaccine may contain purified siderophore receptor proteins derived from a single strain or species of gram-negative bacteria or other organism, which are cross-reactive with siderophores produced by two or more strains, species or genera of gram-negative bacteria. The invention further provides a process for isolating and purifying the siderophore receptor proteins, and for preparing a vaccine containing the proteins. Also provided is a method for diagnosing gram-negative sepsis.
AU19159/95A 1994-02-09 1995-02-09 Active immunization using a siderophore receptor protein Abandoned AU1915995A (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US19404094A 1994-02-09 1994-02-09
US194040 1994-02-09
US385273 1995-02-08
US08/385,273 US5830479A (en) 1994-02-09 1995-02-08 Active immunization using a siderophore receptor protein
PCT/US1995/001739 WO1995021627A1 (en) 1994-02-09 1995-02-09 Active immunization using a siderophore receptor protein

Publications (1)

Publication Number Publication Date
AU1915995A true AU1915995A (en) 1995-08-29

Family

ID=26889631

Family Applications (1)

Application Number Title Priority Date Filing Date
AU19159/95A Abandoned AU1915995A (en) 1994-02-09 1995-02-09 Active immunization using a siderophore receptor protein

Country Status (9)

Country Link
US (4) US6027736A (en)
EP (1) EP0749321B1 (en)
AT (1) ATE352314T1 (en)
AU (1) AU1915995A (en)
CA (1) CA2182976C (en)
DE (1) DE69535374T2 (en)
DK (1) DK0749321T3 (en)
ES (1) ES2279511T3 (en)
WO (1) WO1995021627A1 (en)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2182976C (en) * 1994-02-09 2011-07-12 Daryll A. Emery Active immunization using a siderophore receptor protein
US5830479A (en) * 1994-02-09 1998-11-03 Willmar Poultry Company, Inc. Active immunization using a siderophore receptor protein
US6682754B2 (en) * 1999-11-24 2004-01-27 Willmar Poultry Company, Inc. Ovo delivery of an immunogen containing implant
PT1353689E (en) * 2001-01-03 2006-08-31 Epitopix Llc MUNICIPAL COMPOSITIONS AND METHODS OF USE
IL157041A0 (en) * 2001-01-26 2004-02-08 Inhibitex Inc Monoclonal antibodies to the clfa protein and method of use in treating and preventing infections
EP2147679B1 (en) * 2001-07-25 2014-06-25 Raptor Pharmaceutical, Inc. Compositions for blood-brain barrier transport
CA2539074C (en) 2003-09-19 2017-11-07 Epitopix, Llc Campylobacter polypeptides and methods of use
US20060121039A1 (en) * 2004-12-07 2006-06-08 Alcon, Inc. Use of agents that prevent the generation of amyloid-like proteins and/or drusen, and/or use of agents that promote sequestration and/or degradation of, and/or prevent the neurotoxic effects of such proteins in the treatment of macular degeneration
US20090208535A1 (en) * 2004-06-28 2009-08-20 Proteome Systems Intellectual Property Pty Ltd Novel Methods of Diagnosis of Treatment of P. Aeruginosa Infection and Reagents Therefor
AU2005280147B2 (en) 2004-08-25 2011-02-24 Epitopix, Llc Fusobacterium polypeptides and methods of use
US8729013B2 (en) 2004-08-26 2014-05-20 The University Of Western Ontario Methods of inhibiting staphylobactin-mediated iron uptake in S. aureus
US20100129349A1 (en) * 2004-08-26 2010-05-27 Heinrichs David E Methods of inhibiting staphylobactin-mediated iron uptake in S. aureus
CN101142230A (en) * 2005-01-21 2008-03-12 埃皮托皮克斯有限责任公司 Yersinia spp. polypeptides and methods of use
AU2006214534B2 (en) 2005-02-14 2012-07-19 Epitopix, Llc Polypeptides from Staphylococcus aureus and methods of use
US7794413B2 (en) * 2005-04-19 2010-09-14 Ev3, Inc. Libraries and data structures of materials removed by debulking catheters
US7935355B2 (en) * 2007-04-19 2011-05-03 Nutritional Health Institute Laboratories, Llc Composition and method for controlling intestinal pathogenic organisms
US20080260777A1 (en) * 2007-04-19 2008-10-23 Sotomayor Konky Composition and method for controlling intestinal pathogenic organisms
US7589281B2 (en) * 2007-09-27 2009-09-15 Sabic Innovative Plastics Ip B.V. Flame-retardant poly(arylene ether) composition and its use as a covering for coated wire
US7622522B2 (en) * 2007-09-27 2009-11-24 Sabic Innovative Plastics Ip B.V. Flame-retardant poly(arylene ether) composition and its use as a covering for coated wire
US7655714B2 (en) * 2007-09-27 2010-02-02 Sabic Innovative Plastics Ip B.V. Flame-retardant poly(arylene ether) composition and its use as a covering for coated wire
JP2012521441A (en) 2009-03-23 2012-09-13 エピトピックス,リミティド ライアビリティ カンパニー Immunization compositions containing polypeptides and gram positive polypeptides and methods of use thereof
EP2421529A4 (en) 2009-04-21 2014-01-29 Univ Florida Siderophore conjugate immunogenic compositions and vaccines
WO2011131789A1 (en) * 2010-04-23 2011-10-27 Intervet International B.V. A vaccine comprising inactivated cells of haemophilus parasuis bacteria of serotype 5
US8753643B1 (en) 2012-04-11 2014-06-17 Life-Science Innovations, Llc Spray dried compositions and methods of use
US10100093B2 (en) 2013-12-31 2018-10-16 Epitopix Llc Polypeptides and immunizing compositions containing Burkholderia polypeptides and methods of use
US11000582B2 (en) 2015-07-10 2021-05-11 Epitopix, Llc Proteins and immunizing compositions containing klebsiella proteins and methods of use
EP3373964A1 (en) 2015-11-09 2018-09-19 Epitopix, LLC Polypeptides of fusobacterium and methods of use
US10166280B2 (en) 2016-06-08 2019-01-01 Epitopix, Llc Polypeptides and immunizing compositions containing Bacillus polypeptides and methods of use
MX2019009409A (en) 2017-02-10 2019-09-27 Epitopix Llc Proteins and immunizing compositions containing pasteurella proteins and methods of use.
EP3376021B1 (en) * 2017-03-16 2022-05-04 Ricoh Company, Ltd. Laser device and internal combustion engine
CA3236874A1 (en) * 2021-10-29 2023-05-04 Vaxxinova Us, Inc. Methods and compositions for preventing infection
IL295726A (en) 2022-08-17 2024-03-01 Yeda res & development co ltd Genetically modified bacteria for generating vaccines

Family Cites Families (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4167560A (en) * 1977-04-12 1979-09-11 Texas Vet Lab, Inc. Polyvalent shipping fever vaccine
US4748018A (en) * 1984-02-07 1988-05-31 Stolle Research & Development Corp. Method of passive immunization of mammals using avian antibody
US4530963A (en) * 1982-08-20 1985-07-23 Devoe-Holbein International, N.V. Insoluble chelating compositions
US4452775A (en) * 1982-12-03 1984-06-05 Syntex (U.S.A.) Inc. Cholesterol matrix delivery system for sustained release of macromolecules
US4663161A (en) * 1985-04-22 1987-05-05 Mannino Raphael J Liposome methods and compositions
US4871488A (en) * 1985-04-22 1989-10-03 Albany Medical College Of Union University Reconstituting viral glycoproteins into large phospholipid vesicles
US4681761A (en) * 1985-10-24 1987-07-21 State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education, Acting For And On Behalf Of The Oregon Health Sciences University Major iron-regulated protein of Neisseria gonorrhoeae and its use as vaccine
US4981685A (en) * 1986-03-07 1991-01-01 Utah State University Foundation Bacterial extract vaccines for veterinary application
EP0287206B2 (en) * 1987-03-24 1999-11-24 BTG INTERNATIONAL LIMITED (Company No. 2664412) Vaccine against pasteurella
US5885589A (en) * 1988-04-12 1999-03-23 Intervet International B.V. Pasteurella vaccine
FR2644346B1 (en) 1989-03-20 1994-05-13 Rhone Merieux VACCINES AGAINST SEPTICEMIC BACTERIA, PREPARATIONS OF ANTIGENS OF SEPTICEMIC BACTERIA, NOVEL BACTERIA AND VECTORS FOR THE PREPARATION OF SUCH ANTIGENS OR VACCINES
US5141743A (en) * 1989-04-27 1992-08-25 University Technologies International, Inc. Method for isolating and purifying transferrin and lactoferrin receptor proteins and vaccines containing the same
US5292869A (en) * 1989-04-27 1994-03-08 The Board Of Governors Of The University Method for isolating and purifying transferrin and lactoferrin receptor proteins from bacteria and the preparation of vaccines containing the same
WO1993021951A1 (en) * 1992-04-27 1993-11-11 Michigan State University Method for producing a bacterial vaccine and novel vaccines produced thereby
US5578314A (en) * 1992-05-29 1996-11-26 The Regents Of The University Of California Multiple layer alginate coatings of biological tissue for transplantation
US5534256A (en) * 1992-07-02 1996-07-09 University Of Saskatchewan Haemophilus somnus outer membrane protein extract enriched with iron-regulated proteins
US5439808A (en) * 1993-07-23 1995-08-08 North American Vaccine, Inc. Method for the high level expression, purification and refolding of the outer membrane group B porin proteins from Neisseria meningitidis
US5830479A (en) * 1994-02-09 1998-11-03 Willmar Poultry Company, Inc. Active immunization using a siderophore receptor protein
CA2182976C (en) 1994-02-09 2011-07-12 Daryll A. Emery Active immunization using a siderophore receptor protein
US5538733A (en) * 1994-07-07 1996-07-23 Willmar Poultry Company, Inc. Method of priming an immune response in a one-day old animal
US6121037A (en) 1994-10-18 2000-09-19 Stojiljkovic; Igor Bacterial hemoglobin receptor genes
US6682754B2 (en) 1999-11-24 2004-01-27 Willmar Poultry Company, Inc. Ovo delivery of an immunogen containing implant
US6902747B1 (en) 2000-05-03 2005-06-07 Westfaliasurge, Inc. Iodine-propylene glycol teat dip
PT1353689E (en) 2001-01-03 2006-08-31 Epitopix Llc MUNICIPAL COMPOSITIONS AND METHODS OF USE
US6720160B2 (en) 2001-10-11 2004-04-13 Helica Biosystems, Inc. Method for simultaneous detection of multiple microbial antigens in biological specimens from mastitic animals
US6984503B1 (en) 2002-06-27 2006-01-10 The United States Of America As Represented By The Secretary Of The Agriculture Use of recombinant bovine CD14 in the treatment and prevention of coliform mastitis in dairy cows
CA2539074C (en) 2003-09-19 2017-11-07 Epitopix, Llc Campylobacter polypeptides and methods of use
AU2005280147B2 (en) 2004-08-25 2011-02-24 Epitopix, Llc Fusobacterium polypeptides and methods of use
CN101142230A (en) 2005-01-21 2008-03-12 埃皮托皮克斯有限责任公司 Yersinia spp. polypeptides and methods of use
AU2006214534B2 (en) 2005-02-14 2012-07-19 Epitopix, Llc Polypeptides from Staphylococcus aureus and methods of use

Also Published As

Publication number Publication date
DK0749321T3 (en) 2007-03-12
EP0749321B1 (en) 2007-01-24
US6027736A (en) 2000-02-22
WO1995021627A1 (en) 1995-08-17
US20030064073A1 (en) 2003-04-03
ES2279511T3 (en) 2007-08-16
CA2182976A1 (en) 1995-08-17
DE69535374D1 (en) 2007-03-15
EP0749321A4 (en) 2001-04-25
CA2182976C (en) 2011-07-12
US6432412B1 (en) 2002-08-13
US20060024323A1 (en) 2006-02-02
EP0749321A1 (en) 1996-12-27
DE69535374T2 (en) 2007-08-23
ATE352314T1 (en) 2007-02-15
US7413743B2 (en) 2008-08-19

Similar Documents

Publication Publication Date Title
AU1915995A (en) Active immunization using a siderophore receptor protein
EA200100565A1 (en) NEW STRIPT COCK ANTIGENS
NO319013B1 (en) Vaccine comprising type I surface antigens from Staphylococcus epidermidis, as well as hyperimmune globulins and antibody directed against the type I surface antigen.
FI960977A0 (en) Exported proteins of bacterial origin and noncellular vaccine based thereon
GB9513074D0 (en) Novel anigen
CA2316975A1 (en) Procedures for the extraction and isolation of bacterial capsular polysaccharides for use as vaccines or linked to proteins as conjugate vaccines
GB9224584D0 (en) Use of outer membrane protein d15 and its peptides as vaccine against haempohilus influenzae diseases
DK22389A (en) PROCEDURE AND MEDICINE FOR PROTECTION AGAINST DISEASES CAUSED BY MICRO-ORGANISMS, NAMELY MYCOPLASMA
WO2002004496A3 (en) Fimh adhesin proteins and methods of use
ZA948204B (en) Method for improving utilisation of nutrients by ruminant or ruminant-like animals
CA2217522A1 (en) Isolated frpb nucleic acid molecule and vaccine
SE9003198L (en) FISHVACCIN COMPREHENSIVE AND VIRULENT, INVASIVE BACTERIA
ATE356633T1 (en) VACCIN FOR AN UNTYPABLE HAEMOPHILUS INFLUENZAE STRAIN
IE810618L (en) Pasteurella vaccines
EP0587636B1 (en) Fish vaccine for aeromonas salmonicida infection
Robinson et al. Adult worm homogenate of the nematode parasite Heligmosomoides polygyrus induces proliferation of naive T lymphocytes without MHC restriction
AU673344B2 (en) Vaccines based on streptokinase
Babu et al. Soluble peptidoglycan from Staphylococcus aureus is a murine B-lymphocyte mitogen
US4788059A (en) Equine strangles vaccine and the method of preparing and using the same
PL341541A1 (en) Isolated strains of staphyloccoccus aureus and vaccines prepared of them
DE59708140D1 (en) USE OF AN IMMUNOGLOBULIN PREPARATION FOR THE PRODUCTION OF AN ORAL MEDICINE TO PREVENT THE HEMOLYTIC UREMAL SYNDROME AND PREPARATION THEREFOR
CA2155908A1 (en) Method for improving utilisation of nutrients by ruminant or ruminant-like animals
RU93020246A (en) METHOD OF OBTAINING VACCINES AGAINST CALVES ECHERIHIOZA
TH44467A (en) Campylobacter vaccine