FI960401L - Gener som kodar ett dehydrogenaskomplex av förgrenade alfaketosyror som härrör från Streptomyces avermitilis - Google Patents

Gener som kodar ett dehydrogenaskomplex av förgrenade alfaketosyror som härrör från Streptomyces avermitilis Download PDF

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Publication number
FI960401L
FI960401L FI960401A FI960401A FI960401L FI 960401 L FI960401 L FI 960401L FI 960401 A FI960401 A FI 960401A FI 960401 A FI960401 A FI 960401A FI 960401 L FI960401 L FI 960401L
Authority
FI
Finland
Prior art keywords
branched
genes encoding
keto acid
acid dehydrogenase
streptomyces avermitilis
Prior art date
Application number
FI960401A
Other languages
English (en)
Finnish (fi)
Other versions
FI960401A7 (sv
FI960401A0 (sv
Inventor
Claudio D Denoya
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of FI960401A7 publication Critical patent/FI960401A7/sv
Publication of FI960401A0 publication Critical patent/FI960401A0/sv
Publication of FI960401L publication Critical patent/FI960401L/sv

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Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004Oxidoreductases (1.)
    • C12N9/0008Oxidoreductases (1.) acting on the aldehyde or oxo group of donors (1.2)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00Preparation of compounds containing saccharide radicals
    • C12P19/44Preparation of O-glycosides, e.g. glucosides
    • C12P19/60Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin
    • C12P19/62Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin the hetero ring having eight or more ring members and only oxygen as ring hetero atoms, e.g. erythromycin, spiramycin, nystatin
    • C12P19/623Avermectin; Milbemycin; Ivermectin; C-076
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y102/00Oxidoreductases acting on the aldehyde or oxo group of donors (1.2)
    • C12Y102/04Oxidoreductases acting on the aldehyde or oxo group of donors (1.2) with a disulfide as acceptor (1.2.4)
    • C12Y102/040043-Methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) (1.2.4.4), i.e. branched-chain-alpha-ketoacid dehydrogenase

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
FI960401A 1993-07-30 1994-05-30 Gener som kodar ett dehydrogenaskomplex av förgrenade alfaketosyror som härrör från Streptomyces avermitilis FI960401L (sv)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10051893A 1993-07-30 1993-07-30
PCT/IB1994/000127 WO1995004150A1 (en) 1993-07-30 1994-05-30 Genes encoding branched-chain alpha-ketoacid dehydrogenase complex from streptomyces avermitilis

Publications (3)

Publication Number Publication Date
FI960401A7 FI960401A7 (sv) 1996-01-29
FI960401A0 FI960401A0 (sv) 1996-01-29
FI960401L true FI960401L (sv) 1996-01-29

Family

ID=22280171

Family Applications (1)

Application Number Title Priority Date Filing Date
FI960401A FI960401L (sv) 1993-07-30 1994-05-30 Gener som kodar ett dehydrogenaskomplex av förgrenade alfaketosyror som härrör från Streptomyces avermitilis

Country Status (22)

Country Link
US (1) US5728561A (sv)
EP (1) EP0711349B1 (sv)
JP (1) JP2807348B2 (sv)
KR (1) KR100221385B1 (sv)
CN (2) CN1104502C (sv)
AT (1) ATE248916T1 (sv)
AU (2) AU6657294A (sv)
BR (1) BR9407211A (sv)
CA (1) CA2167520C (sv)
CZ (3) CZ26096A3 (sv)
DE (1) DE69433112T2 (sv)
DK (1) DK0711349T3 (sv)
ES (1) ES2204914T3 (sv)
FI (1) FI960401L (sv)
HU (1) HU218964B (sv)
IL (2) IL110430A (sv)
NO (2) NO321077B1 (sv)
NZ (2) NZ266014A (sv)
PL (3) PL181916B1 (sv)
PT (1) PT711349E (sv)
WO (1) WO1995004150A1 (sv)
ZA (1) ZA945639B (sv)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5466102A (en) * 1993-12-16 1995-11-14 Kennametal Inc. System for coupling machine tools
WO1999000505A1 (en) * 1997-06-30 1999-01-07 The Curators Of The University Of Missouri Use of dna encoding plastid pyruvate dehydrogenase and branched chain oxoacid dehydrogenase components to enhance polyhydroxyalkanoate biosynthesis in plants
US6248579B1 (en) 1998-02-13 2001-06-19 Pfizer Inc Streptomyces avermitilis gene directing the ratio of B2:B1 avermectins
US6197591B1 (en) 1998-09-14 2001-03-06 Pfizer Inc. Streptomyces avermitilis regulatory genes for increased avermectin production
BRPI0013119B8 (pt) * 1999-08-12 2021-05-25 Pah Usa 15 Llc molécula polinucleotídica isolada, vetor recombinante purificado, célula hospedeira procariótica e célula de streptomyces avermitilis mutada, método para obtenção de uma nova cepa de s. avermitilis e processo para produção de avermectinas
EP1210460B1 (en) * 1999-08-19 2007-05-23 Omniscience Pharmaceuticals Gene cloning
CN1321684A (zh) * 2000-04-29 2001-11-14 上海博德基因开发有限公司 一种新的多肽——人krab包含的锌指蛋白kraz2-12和编码这种多肽的多核苷酸
CN1321752A (zh) * 2000-04-29 2001-11-14 上海博德基因开发有限公司 一种新的多肽——人分支alpha-酮酸脱氢酶E1-beta亚单位9和编码这种多肽的多核苷酸
AT410217B (de) * 2000-06-15 2003-03-25 Cistem Biotechnologies Gmbh Vektor und ein verfahren zur expression und selektion randomisierter peptid-sequenzen
EP2141236A1 (en) 2008-07-03 2010-01-06 KRKA, D.D., Novo Mesto Process for production of lipstatin and microorganisms therefore
CN112410389B (zh) * 2019-08-23 2023-07-18 中国科学院微生物研究所 支链α-酮酸脱氢酶复合体在制备丙二酸单酰辅酶A中的应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IN167980B (sv) * 1987-01-23 1991-01-19 Pfizer
IL85119A (en) * 1987-01-23 1993-01-14 Pfizer Streptomyces avermitilis strains, their preparation and use in production of avermectins

Also Published As

Publication number Publication date
PL181778B1 (pl) 2001-09-28
IL110430A (en) 2005-08-31
JPH08507931A (ja) 1996-08-27
HUT71323A (en) 1995-11-28
US5728561A (en) 1998-03-17
CZ289136B6 (cs) 2001-11-14
PL177922B1 (pl) 2000-01-31
DE69433112T2 (de) 2004-04-01
NZ328926A (en) 1998-02-26
HU218964B (hu) 2001-01-29
CN1104502C (zh) 2003-04-02
CZ289866B6 (cs) 2002-04-17
NO20052209D0 (no) 2005-05-04
JP2807348B2 (ja) 1998-10-08
CZ20002929A3 (cs) 2001-11-14
IL154136A0 (en) 2003-07-31
CA2167520A1 (en) 1995-02-09
IL110430A0 (en) 1994-10-21
WO1995004150A1 (en) 1995-02-09
CN1128046A (zh) 1996-07-31
PL312733A1 (en) 1996-05-13
PL181916B1 (en) 2001-10-31
ZA945639B (en) 1996-01-29
NO960372L (no) 1996-01-29
FI960401A7 (sv) 1996-01-29
CZ26096A3 (en) 1996-05-15
AU712442B2 (en) 1999-11-04
AU9421898A (en) 1999-03-04
FI960401A0 (sv) 1996-01-29
EP0711349B1 (en) 2003-09-03
ATE248916T1 (de) 2003-09-15
HU9402192D0 (en) 1994-10-28
NO321077B1 (no) 2006-03-13
KR100221385B1 (ko) 1999-10-01
BR9407211A (pt) 1996-09-17
AU6657294A (en) 1995-02-28
DE69433112D1 (de) 2003-10-09
CA2167520C (en) 1999-07-27
PT711349E (pt) 2003-12-31
CN1208078A (zh) 1999-02-17
NO20052209L (no) 1996-01-29
EP0711349A1 (en) 1996-05-15
NO960372D0 (no) 1996-01-29
ES2204914T3 (es) 2004-05-01
DK0711349T3 (da) 2003-11-24
NZ266014A (en) 1997-11-24

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