FI951992A7 - Uusia substituoituja atsetidinoneja anti-inflammatorisina ja antidegeneratiivisina aineina - Google Patents
Uusia substituoituja atsetidinoneja anti-inflammatorisina ja antidegeneratiivisina aineina Download PDFInfo
- Publication number
- FI951992A7 FI951992A7 FI951992A FI951992A FI951992A7 FI 951992 A7 FI951992 A7 FI 951992A7 FI 951992 A FI951992 A FI 951992A FI 951992 A FI951992 A FI 951992A FI 951992 A7 FI951992 A7 FI 951992A7
- Authority
- FI
- Finland
- Prior art keywords
- inflammatory
- novel substituted
- substituted azetidinones
- antidegenerative agents
- antidegenerative
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
- C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Hematology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Diabetes (AREA)
- Urology & Nephrology (AREA)
- Heart & Thoracic Surgery (AREA)
- Oncology (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Saccharide Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US96680092A | 1992-10-27 | 1992-10-27 | |
| US99183892A | 1992-12-17 | 1992-12-17 | |
| PCT/US1993/010268 WO1994010142A1 (en) | 1992-10-27 | 1993-10-26 | New substituted azetidinones as anti-inflammatory and antidegenerative agents |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FI951992A0 FI951992A0 (fi) | 1995-04-26 |
| FI951992A7 true FI951992A7 (fi) | 1995-04-26 |
Family
ID=27130493
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI951992A FI951992A7 (fi) | 1992-10-27 | 1995-04-26 | Uusia substituoituja atsetidinoneja anti-inflammatorisina ja antidegeneratiivisina aineina |
Country Status (29)
| Country | Link |
|---|---|
| EP (1) | EP0595557B1 (enExample) |
| JP (1) | JPH082868B2 (enExample) |
| KR (1) | KR950704250A (enExample) |
| CN (1) | CN1043884C (enExample) |
| AT (1) | ATE270273T1 (enExample) |
| AU (1) | AU663806B2 (enExample) |
| CA (1) | CA2108584C (enExample) |
| CY (1) | CY2529B1 (enExample) |
| CZ (1) | CZ106895A3 (enExample) |
| DE (1) | DE69333563T2 (enExample) |
| DK (1) | DK0595557T3 (enExample) |
| DZ (1) | DZ1724A1 (enExample) |
| ES (1) | ES2224095T3 (enExample) |
| FI (1) | FI951992A7 (enExample) |
| HR (1) | HRP931309A2 (enExample) |
| HU (2) | HUT72084A (enExample) |
| IL (1) | IL107321A (enExample) |
| LV (1) | LV13338B (enExample) |
| MX (1) | MX9306666A (enExample) |
| MY (1) | MY128261A (enExample) |
| NO (1) | NO305697B1 (enExample) |
| NZ (1) | NZ257755A (enExample) |
| PL (1) | PL308545A1 (enExample) |
| PT (1) | PT595557E (enExample) |
| RU (1) | RU2148056C1 (enExample) |
| SI (1) | SI9300566A (enExample) |
| SK (1) | SK53795A3 (enExample) |
| TW (1) | TW275621B (enExample) |
| WO (1) | WO1994010142A1 (enExample) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5420010A (en) * | 1993-07-30 | 1995-05-30 | Merck & Co., Inc. | Assay for evaluating inhibition of polymorphonuclear leukocyte elastase by N-substituted azetidinones |
| AU5014496A (en) * | 1995-03-23 | 1996-10-08 | Japan Tobacco Inc. | Diphenylmethyl-azetidinone compounds and elastase inhibitor |
| US5523233A (en) * | 1995-05-03 | 1996-06-04 | Merck & Co., Inc. | Enzymatic hydrolysis of 3,3-diethyl-4-[(4-carboxy)phenoxy]-2-azetidinone esters |
| CA2234640A1 (en) * | 1995-10-31 | 1997-05-09 | Merck & Co., Inc. | Process for preparing substituted azetidinones |
| US5808056A (en) * | 1995-10-31 | 1998-09-15 | Merck & Co., Inc. | Process for preparing substituted azetidinones |
| JP2000502079A (ja) * | 1995-12-08 | 2000-02-22 | スミスクライン・ビーチャム・パブリック・リミテッド・カンパニー | アテローム性動脈硬化症の治療のための単環β―ラクタム誘導体 |
| JP2000509049A (ja) * | 1996-04-26 | 2000-07-18 | スミスクライン・ビーチャム・パブリック・リミテッド・カンパニー | アテローム性動脈硬化症の治療用アゼチジノン誘導体 |
| CN1202081C (zh) * | 1998-06-25 | 2005-05-18 | 布里斯托尔-迈尔斯斯奎布公司 | 脒基和胍基β－丙内酰胺类胰蛋白酶抑制剂 |
| AU4654199A (en) * | 1998-07-23 | 2000-02-14 | Shionogi & Co., Ltd. | Monocyclic beta-lactam compounds and chymase inhibitors containing the same |
| RU2191570C1 (ru) * | 2001-04-25 | 2002-10-27 | Закрытое акционерное общество "ВЕРОФАРМ" | Твердая лекарственная форма антимикробного средства |
| RU2207115C1 (ru) * | 2001-12-27 | 2003-06-27 | Закрытое акционерное общество "Брынцалов-А" | Противомикробное средство тариферид |
| RU2217196C2 (ru) * | 2002-02-28 | 2003-11-27 | Небольсин Владимир Евгеньевич | Способ индукции дифференцировки клеток |
| FR2861991B1 (fr) * | 2003-11-07 | 2008-01-18 | Centre Nat Rech Scient | Utilisation d'inhibiteurs de glucosidase pour une therapie de la mucoviscidose |
| FR2937972B1 (fr) * | 2008-11-04 | 2013-03-29 | Galderma Res & Dev | Derives d'oxoazetidine, leur procede de preparation et leur utilisation en medecine humaine ainsi qu'en cosmetique |
| KR101421785B1 (ko) * | 2009-03-09 | 2014-07-22 | 다이호야쿠힌고교 가부시키가이샤 | 프로스타글란딘 ｄ 합성 효소를 저해하는 피페라진 화합물 |
| FR2981933B1 (fr) * | 2011-11-02 | 2013-11-15 | Galderma Res & Dev | Derives d'oxoazetidine, leur procede de preparation et leur utilisation en medecine humaine ainsi qu'en cosmetique |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ228600A (en) * | 1988-04-11 | 1992-02-25 | Merck & Co Inc | 1-(benzylaminocarbonyl)-4-phenoxy-azetidin-2-one derivatives |
| IL99658A0 (en) * | 1990-10-15 | 1992-08-18 | Merck & Co Inc | Substituted azetidinones and pharmaceutical compositions containing them |
| WO1993000332A1 (en) * | 1991-06-25 | 1993-01-07 | Merck & Co., Inc. | Substituted azetidinones as anti-inflammatory and antidegenerative agents |
-
1993
- 1993-10-18 MY MYPI93002128A patent/MY128261A/en unknown
- 1993-10-18 CA CA002108584A patent/CA2108584C/en not_active Expired - Lifetime
- 1993-10-18 TW TW082108642A patent/TW275621B/zh active
- 1993-10-19 HR HR07/991,838A patent/HRP931309A2/xx not_active Application Discontinuation
- 1993-10-19 IL IL10732193A patent/IL107321A/en not_active IP Right Cessation
- 1993-10-22 ES ES93308421T patent/ES2224095T3/es not_active Expired - Lifetime
- 1993-10-22 AT AT93308421T patent/ATE270273T1/de active
- 1993-10-22 PT PT93308421T patent/PT595557E/pt unknown
- 1993-10-22 DK DK93308421T patent/DK0595557T3/da active
- 1993-10-22 DE DE69333563T patent/DE69333563T2/de not_active Expired - Lifetime
- 1993-10-22 EP EP93308421A patent/EP0595557B1/en not_active Expired - Lifetime
- 1993-10-26 WO PCT/US1993/010268 patent/WO1994010142A1/en not_active Ceased
- 1993-10-26 CZ CZ951068A patent/CZ106895A3/cs unknown
- 1993-10-26 PL PL93308545A patent/PL308545A1/xx unknown
- 1993-10-26 NZ NZ257755A patent/NZ257755A/en unknown
- 1993-10-26 RU RU95109936A patent/RU2148056C1/ru active
- 1993-10-26 MX MX9306666A patent/MX9306666A/es not_active IP Right Cessation
- 1993-10-26 HU HU9501184A patent/HUT72084A/hu unknown
- 1993-10-26 CN CN93119648A patent/CN1043884C/zh not_active Expired - Fee Related
- 1993-10-26 SK SK537-95A patent/SK53795A3/sk unknown
- 1993-10-26 AU AU50283/93A patent/AU663806B2/en not_active Expired
- 1993-10-27 SI SI9300566A patent/SI9300566A/sl unknown
- 1993-10-27 DZ DZ930115A patent/DZ1724A1/fr active
- 1993-10-27 JP JP5292692A patent/JPH082868B2/ja not_active Expired - Lifetime
-
1995
- 1995-04-26 FI FI951992A patent/FI951992A7/fi unknown
- 1995-04-26 NO NO951593A patent/NO305697B1/no not_active IP Right Cessation
- 1995-04-27 KR KR1019950701629A patent/KR950704250A/ko not_active Ceased
- 1995-06-30 HU HU95P/P00639P patent/HU211619A9/hu unknown
-
2005
- 2005-06-08 LV LVP-05-69A patent/LV13338B/en unknown
- 2005-08-29 CY CY0500046A patent/CY2529B1/xx unknown
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| FI914833A7 (fi) | Uusia substituoituja atsetidinoneja tulehduksen vastaisina ja rappeutumista estävinä aineina | |
| FI951197L (fi) | Mikrobisidiset koostumukset ja menetelmät | |
| FI931738L (fi) | Teknisk harts-propenymppolymerkomposition | |
| DE69325158D1 (de) | Photokromische Zusammensetzung | |
| FI945625L (fi) | Indolokarbatsoli-imidit ja niiden käyttö | |
| FI944310L (fi) | Heteroaryyliamino- ja heteroaryylisuolfonamidosubstituoituja 3-bentsyyliaminometyylipiperidiinejä ja vastaavia yhdisteitä | |
| FI930404A7 (fi) | Foerfarande foer polymerisering av alfa-olefiner i en gasfas | |
| FI932957L (fi) | Glasfiberfoerstaerkt propenylpolymerkomposition | |
| FI924730L (fi) | Foerfarande foer reglering av molekylviktsfoerdelningen i polymerer | |
| FI935728L (fi) | Substituoituja 4-fenyylipyridoneja ja 4-fenyyli-2-alkoksipyridiinejä | |
| AU1858392A (en) | New substituted azetidinones as anti-inflammatory and antidegenerative agents | |
| FI951992A7 (fi) | Uusia substituoituja atsetidinoneja anti-inflammatorisina ja antidegeneratiivisina aineina | |
| AU5587594A (en) | New substituted azetidinones as anti-inflammatory and antidegenerative agents | |
| FI931456A7 (fi) | Allokering av bandredden i dpnss-naet | |
| FI931735A0 (fi) | Foerfarande foer eliminering av icke-specifika reaktioner i immunanalys | |
| FI933730L (fi) | Foerfarande foer bildning av mellanrum i dragkedja | |
| AU5802894A (en) | New substituted azetidinones as anti-inflammatory and antidegenerative agents | |
| FI911644A7 (fi) | Terapeuttinen yhdiste ja koostumus | |
| FI953106A7 (fi) | Difuoripentapeptidijohdannaiset anti-inflammatorisina aineina | |
| FI932196L (fi) | Foerfarande foer bestaemning av fibrinogen | |
| FI934170A0 (fi) | Foerfarande foer foernyelse av vaermemellanvaeggar i en koksningsugngrupp | |
| FI933300A0 (fi) | Foerfarande foer rengoering av klorvaetesyra i gasform | |
| FI931969L (fi) | Kontrollering av perfusionshastigheter i kontinuerlig bioreaktorodlingav djurceller | |
| DE69217904D1 (de) | Zusammensetzung | |
| FI934142L (fi) | Anordning foer finfoerdelning i materialbaedd av grovt malningsgods |