TW275621B - - Google Patents
Info
- Publication number
- TW275621B TW275621B TW082108642A TW82108642A TW275621B TW 275621 B TW275621 B TW 275621B TW 082108642 A TW082108642 A TW 082108642A TW 82108642 A TW82108642 A TW 82108642A TW 275621 B TW275621 B TW 275621B
- Authority
- TW
- Taiwan
- Prior art keywords
- chem
- 3alkyl
- covalent bond
- 6alkyl
- carboxy
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
- C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Rheumatology (AREA)
- Vascular Medicine (AREA)
- Diabetes (AREA)
- Heart & Thoracic Surgery (AREA)
- Oncology (AREA)
- Pain & Pain Management (AREA)
- Cardiology (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Saccharide Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US96680092A | 1992-10-27 | 1992-10-27 | |
| US99183892A | 1992-12-17 | 1992-12-17 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TW275621B true TW275621B (zh) | 1996-05-11 |
Family
ID=27130493
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TW082108642A TW275621B (zh) | 1992-10-27 | 1993-10-18 |
Country Status (29)
| Country | Link |
|---|---|
| EP (1) | EP0595557B1 (zh) |
| JP (1) | JPH082868B2 (zh) |
| KR (1) | KR950704250A (zh) |
| CN (1) | CN1043884C (zh) |
| AT (1) | ATE270273T1 (zh) |
| AU (1) | AU663806B2 (zh) |
| CA (1) | CA2108584C (zh) |
| CY (1) | CY2529B1 (zh) |
| CZ (1) | CZ106895A3 (zh) |
| DE (1) | DE69333563T2 (zh) |
| DK (1) | DK0595557T3 (zh) |
| DZ (1) | DZ1724A1 (zh) |
| ES (1) | ES2224095T3 (zh) |
| FI (1) | FI951992A0 (zh) |
| HR (1) | HRP931309A2 (zh) |
| HU (2) | HUT72084A (zh) |
| IL (1) | IL107321A (zh) |
| LV (1) | LV13338B (zh) |
| MX (1) | MX9306666A (zh) |
| MY (1) | MY128261A (zh) |
| NO (1) | NO305697B1 (zh) |
| NZ (1) | NZ257755A (zh) |
| PL (1) | PL308545A1 (zh) |
| PT (1) | PT595557E (zh) |
| RU (1) | RU2148056C1 (zh) |
| SI (1) | SI9300566A (zh) |
| SK (1) | SK53795A3 (zh) |
| TW (1) | TW275621B (zh) |
| WO (1) | WO1994010142A1 (zh) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5420010A (en) * | 1993-07-30 | 1995-05-30 | Merck & Co., Inc. | Assay for evaluating inhibition of polymorphonuclear leukocyte elastase by N-substituted azetidinones |
| WO1996029307A1 (fr) * | 1995-03-23 | 1996-09-26 | Japan Tobacco Inc. | Composes de diphenylmethyle-azetidinone et inhibiteur d'elastase |
| US5523233A (en) * | 1995-05-03 | 1996-06-04 | Merck & Co., Inc. | Enzymatic hydrolysis of 3,3-diethyl-4-[(4-carboxy)phenoxy]-2-azetidinone esters |
| JP3081250B2 (ja) * | 1995-10-31 | 2000-08-28 | メルク エンド カンパニー インコーポレーテッド | 置換アゼチジノンの製造方法 |
| US5808056A (en) * | 1995-10-31 | 1998-09-15 | Merck & Co., Inc. | Process for preparing substituted azetidinones |
| EP0869943A1 (en) * | 1995-12-08 | 1998-10-14 | Smithkline Beecham Plc | Monocyclic beta-lactame derivatives for treatment of atherosclerosis |
| HUP9901359A3 (en) * | 1996-04-26 | 2000-03-28 | Smithkline Beecham Plc | Azetidinone derivatives for the treatment of atherosclerosis, process for their producing and pharmaceutical compositions containing them |
| WO2000005204A1 (fr) * | 1998-07-23 | 2000-02-03 | Shionogi & Co., Ltd. | COMPOSES DE β-LACTAME MONOCYCLIQUES ET INHIBITEURS DE LA CHYMASE LES RENFERMANT |
| RU2217196C2 (ru) * | 2002-02-28 | 2003-11-27 | Небольсин Владимир Евгеньевич | Способ индукции дифференцировки клеток |
| FR2937972B1 (fr) * | 2008-11-04 | 2013-03-29 | Galderma Res & Dev | Derives d'oxoazetidine, leur procede de preparation et leur utilisation en medecine humaine ainsi qu'en cosmetique |
| JP5111657B2 (ja) * | 2009-03-09 | 2013-01-09 | 大鵬薬品工業株式会社 | プロスタグランジンｄ合成酵素を阻害するピペラジン化合物 |
| FR2981933B1 (fr) * | 2011-11-02 | 2013-11-15 | Galderma Res & Dev | Derives d'oxoazetidine, leur procede de preparation et leur utilisation en medecine humaine ainsi qu'en cosmetique |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL89835A0 (en) * | 1988-04-11 | 1989-12-15 | Merck & Co Inc | Substituted azetidinones,their preparation and pharmaceutical compositions containing them |
| IL99658A0 (en) * | 1990-10-15 | 1992-08-18 | Merck & Co Inc | Substituted azetidinones and pharmaceutical compositions containing them |
| WO1993000332A1 (en) * | 1991-06-25 | 1993-01-07 | Merck & Co., Inc. | Substituted azetidinones as anti-inflammatory and antidegenerative agents |
-
1993
- 1993-10-18 TW TW082108642A patent/TW275621B/zh active
- 1993-10-18 CA CA002108584A patent/CA2108584C/en not_active Expired - Lifetime
- 1993-10-18 MY MYPI93002128A patent/MY128261A/en unknown
- 1993-10-19 IL IL10732193A patent/IL107321A/en not_active IP Right Cessation
- 1993-10-19 HR HR07/991,838A patent/HRP931309A2/xx not_active Application Discontinuation
- 1993-10-22 DE DE69333563T patent/DE69333563T2/de not_active Expired - Lifetime
- 1993-10-22 EP EP93308421A patent/EP0595557B1/en not_active Expired - Lifetime
- 1993-10-22 ES ES93308421T patent/ES2224095T3/es not_active Expired - Lifetime
- 1993-10-22 AT AT93308421T patent/ATE270273T1/de active
- 1993-10-22 DK DK93308421T patent/DK0595557T3/da active
- 1993-10-22 PT PT93308421T patent/PT595557E/pt unknown
- 1993-10-26 PL PL93308545A patent/PL308545A1/xx unknown
- 1993-10-26 RU RU95109936A patent/RU2148056C1/ru active
- 1993-10-26 NZ NZ257755A patent/NZ257755A/en unknown
- 1993-10-26 AU AU50283/93A patent/AU663806B2/en not_active Expired
- 1993-10-26 CZ CZ951068A patent/CZ106895A3/cs unknown
- 1993-10-26 CN CN93119648A patent/CN1043884C/zh not_active Expired - Fee Related
- 1993-10-26 SK SK537-95A patent/SK53795A3/sk unknown
- 1993-10-26 HU HU9501184A patent/HUT72084A/hu unknown
- 1993-10-26 MX MX9306666A patent/MX9306666A/es not_active IP Right Cessation
- 1993-10-26 WO PCT/US1993/010268 patent/WO1994010142A1/en not_active Application Discontinuation
- 1993-10-27 DZ DZ930115A patent/DZ1724A1/fr active
- 1993-10-27 SI SI9300566A patent/SI9300566A/sl unknown
- 1993-10-27 JP JP5292692A patent/JPH082868B2/ja not_active Expired - Lifetime
-
1995
- 1995-04-26 NO NO951593A patent/NO305697B1/no not_active IP Right Cessation
- 1995-04-26 FI FI951992A patent/FI951992A0/fi unknown
- 1995-04-27 KR KR1019950701629A patent/KR950704250A/ko not_active Application Discontinuation
- 1995-06-30 HU HU95P/P00639P patent/HU211619A9/hu unknown
-
2005
- 2005-06-08 LV LVP-05-69A patent/LV13338B/en unknown
- 2005-08-29 CY CY0500046A patent/CY2529B1/xx unknown
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