FI943798A - Kasvaimenvastaisen vaikutuksen lisäämiseen tarkoitettuja heterosyklisiä yhdisteitä - Google Patents

Kasvaimenvastaisen vaikutuksen lisäämiseen tarkoitettuja heterosyklisiä yhdisteitä Download PDF

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Publication number
FI943798A
FI943798A FI943798A FI943798A FI943798A FI 943798 A FI943798 A FI 943798A FI 943798 A FI943798 A FI 943798A FI 943798 A FI943798 A FI 943798A FI 943798 A FI943798 A FI 943798A
Authority
FI
Finland
Prior art keywords
heterocyclic compounds
antitumor activity
enhancing antitumor
enhancing
activity
Prior art date
Application number
FI943798A
Other languages
English (en)
Swedish (sv)
Other versions
FI943798A0 (fi
Inventor
Jotham W Coe
Anton F J Fliri
Takushi Kaneko
Eric R Larson
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of FI943798A publication Critical patent/FI943798A/fi
Publication of FI943798A0 publication Critical patent/FI943798A0/fi

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/16—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FI943798A 1992-02-19 1994-08-18 Kasvaimenvastaisen vaikutuksen lisäämiseen tarkoitettuja heterosyklisiä yhdisteitä FI943798A0 (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US83862292A 1992-02-19 1992-02-19
PCT/US1992/009554 WO1993017021A1 (en) 1992-02-19 1992-11-17 Heterocyclic compounds for enhancing antitumor activity

Publications (2)

Publication Number Publication Date
FI943798A true FI943798A (fi) 1994-08-18
FI943798A0 FI943798A0 (fi) 1994-08-18

Family

ID=25277611

Family Applications (1)

Application Number Title Priority Date Filing Date
FI943798A FI943798A0 (fi) 1992-02-19 1994-08-18 Kasvaimenvastaisen vaikutuksen lisäämiseen tarkoitettuja heterosyklisiä yhdisteitä

Country Status (6)

Country Link
US (1) US5583137A (fi)
EP (1) EP0626964A1 (fi)
JP (1) JPH08828B2 (fi)
CA (1) CA2129337A1 (fi)
FI (1) FI943798A0 (fi)
WO (1) WO1993017021A1 (fi)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2258556A1 (en) * 1996-06-17 1997-12-24 Julian Stanley Kroin Drug resistance and multidrug resistance modulators
US5776939A (en) * 1997-06-12 1998-07-07 Eli Lilly And Company Drug resistance and multidrug resistance modulators
JP2001522853A (ja) 1997-11-11 2001-11-20 ファイザー・プロダクツ・インク 抗癌剤として有用なチエノピリミジンおよびチエノピリジン誘導体
GB9918035D0 (en) 1999-07-30 1999-09-29 Novartis Ag Organic compounds
JP2003535867A (ja) 2000-06-06 2003-12-02 ファイザー プロダクツ インコーポレイテッド 抗癌剤として有用なチオフェン誘導体
US6693099B2 (en) 2000-10-17 2004-02-17 The Procter & Gamble Company Substituted piperazine compounds optionally containing a quinolyl moiety for treating multidrug resistance
US6376514B1 (en) 2000-10-17 2002-04-23 The Procter & Gamble Co. Substituted six-membered heterocyclic compounds useful for treating multidrug resistance and compositions and methods thereof
PE20030008A1 (es) 2001-06-19 2003-01-22 Bristol Myers Squibb Co Inhibidores duales de pde 7 y pde 4
AU2002364211A1 (en) * 2001-12-21 2003-07-15 Bayer Pharmaceuticals Corporation Thienopyrimidine derivative compounds as inhibitors of prolylpeptidase, inducers of apoptosis and cancer treatment agents
AR044743A1 (es) * 2002-09-26 2005-10-05 Nihon Nohyaku Co Ltd Herbicida, metodo de emplearlo, derivados de tienopirimidina sustituida,compuestos intermediarios, y procedimientos que se utilizan para producirlos,
JP2004224756A (ja) * 2003-01-24 2004-08-12 Sumika Fine Chemicals Co Ltd ２，６−ジハロゲノ−８−置換−プリン化合物およびその製造方法
US20040242568A1 (en) * 2003-03-25 2004-12-02 Syrrx, Inc. Dipeptidyl peptidase inhibitors
CA2676138A1 (en) * 2007-01-26 2008-08-07 Irm Llc Compounds and compositions as kinase inhibitors
TW201100427A (en) 2009-03-31 2011-01-01 Arqule Inc Substituted heterocyclic compounds

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3016378A (en) * 1959-07-01 1962-01-09 Thomae Gmbh Dr K Amino-substituted purine derivatives
FR1281229A (fr) * 1959-11-09 1962-01-12 Thomae Gmbh Dr K Perfectionnements apportés aux procédés de préparation de dérivés de la purine amino-substitués
RO62428A (fr) * 1971-05-04 1978-01-15 Thomae Gmbh Dr K Procede pour la preparation des thyeno-(3,2-d)-pyrimidines
DE2200764A1 (de) * 1972-01-07 1973-07-12 Thomae Gmbh Dr K Neue thieno eckige klammer aff 2,3-d eckige klammer zu pyrimidine und verfahren zu ihrer herstellung
JPS5942387A (ja) * 1982-07-21 1984-03-08 Sankyo Co Ltd チエノピリミジン誘導体および殺虫、殺ダニ剤
DE3529497A1 (de) * 1985-08-17 1987-02-26 Boehringer Mannheim Gmbh N(pfeil hoch)6(pfeil hoch)-disubstituierte purinderivate, verfahren zu deren herstellung sowie diese verbindungen enthaltende arzneimittel
IL87149A (en) * 1987-07-20 1994-05-30 Merck & Co Inc 6-Piperazinyl derivatives of purine and its 3- and 9-deaza isosteres, their preparation and pharmaceutical compositions containing them
GB8912335D0 (en) * 1989-05-30 1989-07-12 Smithkline Beckman Intercredit Compounds
GB8912336D0 (en) * 1989-05-30 1989-07-12 Smithkline Beckman Intercredit Compounds

Also Published As

Publication number Publication date
JPH08828B2 (ja) 1996-01-10
FI943798A0 (fi) 1994-08-18
CA2129337A1 (en) 1993-09-02
WO1993017021A1 (en) 1993-09-02
JPH07500115A (ja) 1995-01-05
EP0626964A1 (en) 1994-12-07
US5583137A (en) 1996-12-10

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