FI942792L - Lipoksigenaasia inhiboivia imidatsoliyhdisteitä - Google Patents

Lipoksigenaasia inhiboivia imidatsoliyhdisteitä Download PDF

Info

Publication number
FI942792L
FI942792L FI942792A FI942792A FI942792L FI 942792 L FI942792 L FI 942792L FI 942792 A FI942792 A FI 942792A FI 942792 A FI942792 A FI 942792A FI 942792 L FI942792 L FI 942792L
Authority
FI
Finland
Prior art keywords
lipoxygenase
inhibiting
imidazole compounds
imidazole
compounds
Prior art date
Application number
FI942792A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI942792A0 (fi
FI942792A7 (fi
Inventor
Rodney W Stevens
Takashi Mano
Kazuo Ando
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of FI942792A0 publication Critical patent/FI942792A0/fi
Publication of FI942792A7 publication Critical patent/FI942792A7/fi
Publication of FI942792L publication Critical patent/FI942792L/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D249/00Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/081,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Rheumatology (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Biomedical Technology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
FI942792A 1993-06-14 1994-06-13 Lipoksigenaasia inhiboivia imidatsoliyhdisteitä FI942792L (fi)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP14220693 1993-06-14

Publications (3)

Publication Number Publication Date
FI942792A0 FI942792A0 (fi) 1994-06-13
FI942792A7 FI942792A7 (fi) 1994-12-15
FI942792L true FI942792L (fi) 1994-12-15

Family

ID=15309865

Family Applications (1)

Application Number Title Priority Date Filing Date
FI942792A FI942792L (fi) 1993-06-14 1994-06-13 Lipoksigenaasia inhiboivia imidatsoliyhdisteitä

Country Status (23)

Country Link
US (1) US5753682A (cs)
EP (1) EP0703913B1 (cs)
KR (1) KR100190728B1 (cs)
CN (2) CN1050840C (cs)
AT (1) ATE154353T1 (cs)
AU (1) AU685122B2 (cs)
BR (1) BR9406822A (cs)
CA (1) CA2163667C (cs)
CZ (1) CZ282969B6 (cs)
DE (1) DE69403795T2 (cs)
DK (1) DK0703913T3 (cs)
ES (1) ES2103130T3 (cs)
FI (1) FI942792L (cs)
GR (1) GR3024568T3 (cs)
HU (1) HUT70767A (cs)
IL (1) IL109903A (cs)
NO (1) NO955046L (cs)
NZ (1) NZ266541A (cs)
PL (2) PL175987B1 (cs)
RU (1) RU2126004C1 (cs)
TW (1) TW374088B (cs)
WO (1) WO1994029299A1 (cs)
ZA (1) ZA944140B (cs)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5883106A (en) * 1994-10-18 1999-03-16 Pfizer Inc. 5-lipoxygenase inhibitors
US6063928A (en) * 1994-10-18 2000-05-16 Pfizer Inc 5-lipoxygenase inhibitors
SK281577B6 (sk) * 1994-10-18 2001-05-10 Pfizer Inc. Heterocyklické zlúčeniny a farmaceutický prostriedok na ich báze
PT863905E (pt) * 1995-09-18 2001-03-30 Pfizer Novos inibidores da lipoxigenase do imidazolo
KR100400051B1 (ko) * 1998-04-29 2003-09-29 더 프록터 앤드 갬블 캄파니 1,3-이치환-4-옥소환식 요소의 제조 방법
JP4549531B2 (ja) * 1998-04-29 2010-09-22 ザ プロクター アンド ギャンブル カンパニー 1,3−二置換−4−オキソ環式尿素の製造方法
US6194585B1 (en) * 1998-12-22 2001-02-27 Pfizer Inc. Process for preparing 5-lipoxygenase inhibitors
US6344563B1 (en) * 1999-08-31 2002-02-05 Timothy Norris Process for making 5-lipoxygenase inhibitors having varied heterocyclic ring systems
RS20090211A (en) 2006-11-27 2010-10-31 Pfizer Products Inc. Pyrazole analogs

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1183847A (en) * 1981-10-01 1985-03-12 Georges Van Daele N-(3-hydroxy-4-piperidinyl)benzamide derivatives
DE3374656D1 (en) * 1982-08-12 1988-01-07 Smith & Nephew Ass Wound dressing and its manufacture
JPS60142966A (ja) * 1983-09-05 1985-07-29 Yoshitomi Pharmaceut Ind Ltd イミダゾ−ル誘導体
US4851526A (en) * 1987-09-04 1989-07-25 Schering A.G. 1-(4-Substituted phenyl)-1H-imidazoles compounds
GB8926981D0 (en) * 1988-12-23 1990-01-17 Ici Plc Heterocyclic derivatives
US5234950A (en) * 1988-12-23 1993-08-10 Imperial Chemical Industries Plc Tetrahydrofuran derivatives
US5223525A (en) * 1989-05-05 1993-06-29 Rhone-Poulenc Ag Company Pesticidal 1-arylimidazoles
IE64358B1 (en) * 1989-07-18 1995-07-26 Ici Plc Diaryl ether heterocycles
IE913866A1 (en) * 1990-11-28 1992-06-03 Ici Plc Aryl derivatives
GB9101375D0 (en) * 1991-01-22 1991-03-06 Erba Carlo Spa N-imidazolyl derivatives of substituted tetrahydrocarbazole and cyclohepht(b)indole
GB9108811D0 (en) * 1991-04-24 1991-06-12 Erba Carlo Spa N-imidazolyl derivatives of substituted indole

Also Published As

Publication number Publication date
FI942792A0 (fi) 1994-06-13
PL175987B1 (pl) 1999-03-31
US5753682A (en) 1998-05-19
DK0703913T3 (da) 1997-10-20
EP0703913A1 (en) 1996-04-03
FI942792A7 (fi) 1994-12-15
ATE154353T1 (de) 1997-06-15
GR3024568T3 (en) 1997-12-31
CA2163667A1 (en) 1994-12-22
HU9401762D0 (en) 1994-09-28
ZA944140B (en) 1995-12-13
DE69403795D1 (de) 1997-07-17
CZ282969B6 (cs) 1997-11-12
CN1125442A (zh) 1996-06-26
AU6807794A (en) 1995-01-03
NZ266541A (en) 1997-11-24
RU2126004C1 (ru) 1999-02-10
KR960703121A (ko) 1996-06-19
NO955046L (no) 1996-02-13
CN1247191A (zh) 2000-03-15
DE69403795T2 (de) 1997-09-18
TW374088B (en) 1999-11-11
PL312006A1 (en) 1996-04-01
ES2103130T3 (es) 1997-08-16
HUT70767A (en) 1995-10-30
NO955046D0 (no) 1995-12-13
CN1050840C (zh) 2000-03-29
CA2163667C (en) 1998-12-15
PL176522B1 (pl) 1999-06-30
IL109903A (en) 1998-10-30
EP0703913B1 (en) 1997-06-11
AU685122B2 (en) 1998-01-15
CZ327695A3 (en) 1996-05-15
KR100190728B1 (ko) 1999-06-01
WO1994029299A1 (en) 1994-12-22
BR9406822A (pt) 1996-03-26
IL109903A0 (en) 1994-10-07

Similar Documents

Publication Publication Date Title
FI954327L (fi) Atsasykloheksapeptidiyhdisteitä
BR1101108A (pt) Composto
FI961696L (fi) Pyridatsinokinoliiniyhdisteitä
ID16345A (id) Senyawa-senyawa heterosiklik
ATE258166T1 (de) Substituierte benzylaminpiperidin-verbindungen
FI945690L (fi) Substituoitu N-piperidino-3-pyratsolikarboksamidi
FI940154L (fi) Substituoidut dialkyylitioeetterit
FI954016A7 (fi) Uudet yhdisteet
NO982566D0 (no) Forbindelser
DK72693D0 (da) Compounds
DE59403503D1 (de) Substituierte 1-Aryltriazolinone
NO974170D0 (no) Polyazacykloalkan-forbindelser
FI945763L (fi) Herbisidiset yhdisteet
FI942792A7 (fi) Lipoksigenaasia inhiboivia imidatsoliyhdisteitä
DK124393D0 (da) Compounds
FI944825A7 (fi) Fenyylibentsoamidipohjaiset fungsidiyhdisteet
DE69418077D1 (de) Organosiliziumverbindungen
FI956304L (fi) Substituoidut aryltioalkyylitiopyridiinit
NO930791D0 (no) Substituerte tinnsilikatforbindelser
FI954017L (fi) Uudet yhdisteet
BR9405830A (pt) Oxazois substituidos
FI943637A7 (fi) Aryylialkoksifenoksi-imidatsoliiniyhdisteitä
DK102693D0 (da) Novel compounds
DK71893D0 (da) Heterocykliske forbindelser
SE9304269D0 (sv) Heterocyclic compounds