FI941490A - Förfarande för framställning av antimikrobiella kinolonyllaktamer - Google Patents

Förfarande för framställning av antimikrobiella kinolonyllaktamer Download PDF

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Publication number
FI941490A
FI941490A FI941490A FI941490A FI941490A FI 941490 A FI941490 A FI 941490A FI 941490 A FI941490 A FI 941490A FI 941490 A FI941490 A FI 941490A FI 941490 A FI941490 A FI 941490A
Authority
FI
Finland
Prior art keywords
quinolone
compound
lactam
moiety
steps
Prior art date
Application number
FI941490A
Other languages
English (en)
Finnish (fi)
Other versions
FI941490A0 (sv
Inventor
Ronald Eugene White
Jr Thomas Prosser Demuth
Original Assignee
Procter & Gamble Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Procter & Gamble Pharma filed Critical Procter & Gamble Pharma
Publication of FI941490A0 publication Critical patent/FI941490A0/sv
Publication of FI941490A publication Critical patent/FI941490A/sv

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D505/00—Heterocyclic compounds containing 5-oxa-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. oxacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
    • C07D477/02—Preparation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D499/88—Compounds with a double bond between positions 2 and 3 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
FI941490A 1991-10-01 1994-03-30 Förfarande för framställning av antimikrobiella kinolonyllaktamer FI941490A (sv)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US76961591A 1991-10-01 1991-10-01
PCT/US1992/008246 WO1993007154A1 (en) 1991-10-01 1992-09-28 Process for making antimicrobial quinolonyl lactams

Publications (2)

Publication Number Publication Date
FI941490A0 FI941490A0 (sv) 1994-03-30
FI941490A true FI941490A (sv) 1994-05-02

Family

ID=25085987

Family Applications (1)

Application Number Title Priority Date Filing Date
FI941490A FI941490A (sv) 1991-10-01 1994-03-30 Förfarande för framställning av antimikrobiella kinolonyllaktamer

Country Status (22)

Country Link
US (1) US5281703A (sv)
EP (1) EP0606336B1 (sv)
KR (1) KR100253825B1 (sv)
CN (1) CN1046523C (sv)
AT (1) ATE150463T1 (sv)
AU (1) AU667837B2 (sv)
BR (1) BR9206590A (sv)
CA (1) CA2120493A1 (sv)
CZ (1) CZ73194A3 (sv)
DE (1) DE69218445T2 (sv)
DK (1) DK0606336T3 (sv)
ES (1) ES2101119T3 (sv)
FI (1) FI941490A (sv)
GR (1) GR3023227T3 (sv)
HU (1) HUT67423A (sv)
MX (1) MX9205620A (sv)
NO (1) NO304599B1 (sv)
NZ (1) NZ244557A (sv)
PT (1) PT100920B (sv)
RU (1) RU2130938C1 (sv)
SK (1) SK37594A3 (sv)
WO (1) WO1993007154A1 (sv)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5646163A (en) * 1992-10-30 1997-07-08 The Procter & Gamble Company Quinolone 5-(N-heterosubstituted amino) antimicrobials
EP0661030B1 (en) * 1993-12-28 2000-07-12 Kao Corporation Sanitary napkin
CN1159809A (zh) * 1994-08-02 1997-09-17 普罗克特和甘保尔公司 喹诺酮基内酰胺抗微生物化合物和新型的中间体化合物的制备方法
NZ290721A (en) * 1994-08-02 1999-03-29 Procter & Gamble Process for making quinolone-containing antimicrobial compounds
US5607928A (en) * 1994-08-05 1997-03-04 Zeneca Limited Carbapenem derivatives containing a bicyclic ketone substituent and their use as anti-infectives
EP0695753A1 (en) * 1994-08-05 1996-02-07 Zeneca Limited Carbapenem derivatives containing a bicyclic substituent, process for their preparation, and their use
US5693791A (en) * 1995-04-11 1997-12-02 Truett; William L. Antibiotics and process for preparation
WO1999028308A1 (en) * 1997-11-29 1999-06-10 Truett William L Antibiotics and process for preparation
US6437119B1 (en) 1998-05-07 2002-08-20 William Lawrence Truett Compounds formed from two or three antibiotics and their processes of preparation
US6638908B1 (en) * 2000-08-09 2003-10-28 Yale University Crystals of the large ribosomal subunit
US6947844B2 (en) * 2000-08-09 2005-09-20 Yale University Modulators of ribosomal function and identification thereof
IN191798B (sv) 2000-11-03 2004-01-03 Ranbaxy Lab Ltd
ES2213648T3 (es) 2001-03-30 2004-09-01 Dar Al Dawa Development, And Investment Co. Derivados de quinolin-4-ona y su uso como antibioticos.
IL151012A0 (en) * 2001-08-03 2003-02-12 Ribosomes Structure And Protei Ribosomes structure and protein synthesis inhibitors
US6952650B2 (en) 2001-08-03 2005-10-04 Yale University Modulators of ribosomal function and identification thereof
AR043050A1 (es) 2002-09-26 2005-07-13 Rib X Pharmaceuticals Inc Compuestos heterociclicos bifuncionales y metodos para preparar y usar los mismos
MXPA05009430A (es) * 2003-03-05 2006-04-07 Rib X Pharmaceuticals Inc Compuestos heterociclicos bifuncionales y metodos para hacer y usar a los mismos.
JP2007509980A (ja) * 2003-10-30 2007-04-19 リブ−エックス ファーマシューティカルズ，インコーポレイテッド 二官能性マクロライド複素環式化合物およびそれらの化合物を調製および使用する方法
WO2005049632A1 (en) * 2003-11-18 2005-06-02 Rib-X Pharmaceuticals, Inc. Bifunctional macrolide heterocyclic compounds and methods of making and using the same
US8202843B2 (en) 2004-02-27 2012-06-19 Rib-X Pharmaceuticals, Inc. Macrocyclic compounds and methods of making and using the same

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUT49889A (en) * 1988-03-31 1989-11-28 Hoffmann La Roche Process for producing acyl derivatives
EP0366193A3 (en) * 1988-10-24 1992-01-08 Norwich Eaton Pharmaceuticals, Inc. Novel antimicrobial quinolonyl lactams
EP0366189A3 (en) * 1988-10-24 1992-01-02 Norwich Eaton Pharmaceuticals, Inc. Novel antimicrobial lactam-quinolones
SG54293A1 (en) * 1988-10-24 1998-11-16 Procter & Gamble Pharma Novel antimicrobial fluoroquinolonyl cephems
SG67307A1 (en) * 1988-10-24 1999-09-21 Procter & Gamble Pharma Novel antimicrobial quinolonyl lactam esters
ZA912279B (en) * 1990-04-09 1992-02-26 Hoffmann La Roche Carbapenem compounds
ATE193890T1 (de) * 1990-04-18 2000-06-15 Procter & Gamble Pharma Antimikrobielle chinolonyl-lactame

Also Published As

Publication number Publication date
DE69218445D1 (de) 1997-04-24
CN1075146A (zh) 1993-08-11
ATE150463T1 (de) 1997-04-15
FI941490A0 (sv) 1994-03-30
DK0606336T3 (da) 1997-04-14
HU9400940D0 (en) 1994-06-28
BR9206590A (pt) 1995-04-25
CA2120493A1 (en) 1993-04-15
PT100920A (pt) 1993-10-29
EP0606336B1 (en) 1997-03-19
US5281703A (en) 1994-01-25
WO1993007154A1 (en) 1993-04-15
SK37594A3 (en) 1995-02-08
PT100920B (pt) 1999-07-30
NO941108L (no) 1994-05-31
DE69218445T2 (de) 1997-08-07
NZ244557A (en) 1996-02-27
MX9205620A (es) 1993-12-01
ES2101119T3 (es) 1997-07-01
HUT67423A (en) 1995-04-28
CN1046523C (zh) 1999-11-17
CZ73194A3 (en) 1994-11-16
EP0606336A1 (en) 1994-07-20
KR100253825B1 (ko) 2000-05-01
NO941108D0 (no) 1994-03-25
AU2693892A (en) 1993-05-03
GR3023227T3 (en) 1997-07-30
RU2130938C1 (ru) 1999-05-27
NO304599B1 (no) 1999-01-18
AU667837B2 (en) 1996-04-18

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