FI941212A0 - Fuusioituneet trisykliset, typpeä sisältävät heterosykliset yhdisteet - Google Patents

Fuusioituneet trisykliset, typpeä sisältävät heterosykliset yhdisteet

Info

Publication number
FI941212A0
FI941212A0 FI941212A FI941212A FI941212A0 FI 941212 A0 FI941212 A0 FI 941212A0 FI 941212 A FI941212 A FI 941212A FI 941212 A FI941212 A FI 941212A FI 941212 A0 FI941212 A0 FI 941212A0
Authority
FI
Finland
Prior art keywords
pct
containing heterocyclic
heterocyclic compounds
sulfur
compounds
Prior art date
Application number
FI941212A
Other languages
English (en)
Swedish (sv)
Other versions
FI941212A (fi
Inventor
John A Lowe Iii
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of FI941212A publication Critical patent/FI941212A/fi
Publication of FI941212A0 publication Critical patent/FI941212A0/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
FI941212A 1991-09-26 1994-03-15 Fuusioituneet trisykliset, typpeä sisältävät heterosykliset yhdisteet FI941212A0 (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US76648891A 1991-09-26 1991-09-26
PCT/US1992/006819 WO1993006099A1 (en) 1991-09-16 1992-08-20 Fused tricyclic nitrogen containing heterocycles as substance p receptor antagonists

Publications (2)

Publication Number Publication Date
FI941212A FI941212A (fi) 1994-03-15
FI941212A0 true FI941212A0 (fi) 1994-03-15

Family

ID=25076576

Family Applications (1)

Application Number Title Priority Date Filing Date
FI941212A FI941212A0 (fi) 1991-09-26 1994-03-15 Fuusioituneet trisykliset, typpeä sisältävät heterosykliset yhdisteet

Country Status (19)

Country Link
US (1) US5527808A (fi)
EP (1) EP0607164B1 (fi)
JP (1) JP2535134B2 (fi)
CN (1) CN1071168A (fi)
AT (1) ATE216996T1 (fi)
AU (1) AU2481292A (fi)
BR (1) BR9206500A (fi)
CA (1) CA2118704C (fi)
CZ (1) CZ59394A3 (fi)
DE (1) DE69232588T2 (fi)
DK (1) DK0607164T3 (fi)
ES (1) ES2174836T3 (fi)
FI (1) FI941212A0 (fi)
HU (1) HU9400728D0 (fi)
MX (1) MX9205242A (fi)
NO (1) NO940927L (fi)
PT (1) PT100901A (fi)
WO (1) WO1993006099A1 (fi)
ZA (1) ZA927370B (fi)

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FR2700472B1 (fr) 1993-01-19 1995-02-17 Rhone Poulenc Rorer Sa Association synergisante ayant un effet antagoniste des récepteurs NK1 et NK2.
US5393762A (en) * 1993-06-04 1995-02-28 Pfizer Inc. Pharmaceutical agents for treatment of emesis
EP0653208A3 (en) * 1993-11-17 1995-10-11 Pfizer Substance P antagonists for the treatment or prevention of sunburn.
EP0659409A3 (en) * 1993-11-23 1995-08-09 Pfizer Substance P antagonists for the inhibition of angiogenesis.
EP0655246A1 (en) * 1993-11-30 1995-05-31 Pfizer Inc. Substance P antagonists for the treatment of disorders caused by helicobacter pylori or other spiral urease-positive gram-negative bacteria
IL116249A (en) * 1994-12-12 2003-07-06 Pfizer Nk-1 receptor antagonists for the treatment of neuronal damage and stroke
FR2728169A1 (fr) * 1994-12-19 1996-06-21 Oreal Utilisation d'un antagoniste de substance p pour le traitement des prurits et des dysesthesies oculaires ou palpebrales
FR2728265A1 (fr) * 1994-12-19 1996-06-21 Oreal Utilisation d'un antagoniste de substance p dans une composition pharmaceutique
FR2728166A1 (fr) 1994-12-19 1996-06-21 Oreal Composition topique contenant un antagoniste de substance p
FR2728165A1 (fr) 1994-12-19 1996-06-21 Oreal Utilisation d'un antagoniste de substance p pour le traitement des rougeurs cutanees d'origine neurogene
TW458774B (en) 1995-10-20 2001-10-11 Pfizer Antiemetic pharmaceutical compositions
FR2741262B1 (fr) 1995-11-20 1999-03-05 Oreal Utilisation d'un antagoniste de tnf-alpha pour le traitement des rougeurs cutanees d'origine neurogene
CA2324116A1 (en) * 1999-10-25 2001-04-25 Susan Beth Sobolov-Jaynes Nk-1 receptor antagonists and eletriptan for the treatment of migraine
RU2309953C2 (ru) 1999-11-03 2007-11-10 Эймр Текнолоджи, Инк. Арил- и гетероарилзамещенные тетрагидроизохинолины, фармацевтическая композиция и способ лечения на их основе
US7163949B1 (en) 1999-11-03 2007-01-16 Amr Technology, Inc. 4-phenyl substituted tetrahydroisoquinolines and use thereof
KR100821410B1 (ko) 2000-07-11 2008-04-10 에이엠알 테크놀로지, 인크. 4-페닐 치환된 테트라하이드로이소퀴놀린 및 이의치료학적 용도
US20020049211A1 (en) * 2000-09-06 2002-04-25 Sobolov-Jaynes Susan Beth Combination treatment for depression and anxiety
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ZA200701232B (en) 2004-07-15 2008-08-27 Amr Technology Inc Aryl-and heteroaryl-substituted tetrahydroisoquinolines and use thereof to block reuptake of norepinephrine, dopamine and serotonin
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US8293900B2 (en) 2005-09-29 2012-10-23 Merck Sharp & Dohme Corp Acylated spiropiperidine derivatives as melanocortin-4 receptor modulators
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CA2664113C (en) 2006-09-22 2013-05-28 Merck & Co., Inc. Use of platencin and platensimycin as fatty acid synthesis inhibitors to treat obesity, diabetes and cancer
US20110218176A1 (en) 2006-11-01 2011-09-08 Barbara Brooke Jennings-Spring Compounds, methods, and treatments for abnormal signaling pathways for prenatal and postnatal development
BRPI0806245B1 (pt) 2007-01-10 2022-01-25 Msd Italia S.R.L. Compostos de fórmula i e seus usos
CA2682727C (en) 2007-04-02 2016-03-22 Banyu Pharmaceutical Co., Ltd. Indoledione derivative
EP2170076B1 (en) 2007-06-27 2016-05-18 Merck Sharp & Dohme Corp. 4-carboxybenzylamino derivatives as histone deacetylase inhibitors
US8598184B2 (en) 2008-03-03 2013-12-03 Tiger Pharmatech Protein kinase inhibitors
US9156812B2 (en) 2008-06-04 2015-10-13 Bristol-Myers Squibb Company Crystalline form of 6-[(4S)-2-methyl-4-(2-naphthyl)-1,2,3,4-tetrahydroisoquinolin-7-yl]pyridazin-3-amine
UA105182C2 (ru) 2008-07-03 2014-04-25 Ньюрексон, Інк. Бензоксазины, бензотиазины и родственные соединения, которые имеют ингибирующую nos активность
CA2756255A1 (en) 2009-03-27 2010-09-30 Presidio Pharmaceuticals, Inc. Substituted bicyclic hcv inhibitors
US8691825B2 (en) 2009-04-01 2014-04-08 Merck Sharp & Dohme Corp. Inhibitors of AKT activity
KR20120034644A (ko) 2009-05-12 2012-04-12 알바니 몰레큘라 리써치, 인크. 아릴, 헤테로아릴, 및 헤테로사이클 치환된 테트라하이드로이소퀴놀린 및 이의 용도
CN102638982B (zh) 2009-05-12 2015-07-08 百时美施贵宝公司 (S)-7-([1,2,4]三唑并[1,5-a]吡啶-6-基)-4-(3,4-二氯苯基)-1,2,3,4-四氢异喹啉的晶型及其用途
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US8883801B2 (en) 2010-08-23 2014-11-11 Merck Sharp & Dohme Corp. Substituted pyrazolo[1,5-a]pyrimidines as mTOR inhibitors
US8946216B2 (en) 2010-09-01 2015-02-03 Merck Sharp & Dohme Corp. Indazole derivatives useful as ERK inhibitors
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Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3534053A (en) * 1967-05-24 1970-10-13 American Home Prod Quinuclidine derivatives
US3506673A (en) * 1968-03-29 1970-04-14 Aldrich Chem Co Inc 2-(4'halo)-benzhydryl-3-quinuclidinols
MX18467A (es) * 1988-11-23 1993-07-01 Pfizer Agentes terapeuticos de quinuclidinas
EP0540526B1 (en) * 1990-07-23 1994-12-28 Pfizer Inc. Quinuclidine derivatives

Also Published As

Publication number Publication date
CA2118704A1 (en) 1993-04-01
FI941212A (fi) 1994-03-15
MX9205242A (es) 1993-03-01
CZ59394A3 (en) 1994-11-16
DK0607164T3 (da) 2002-06-17
JPH06507179A (ja) 1994-08-11
CA2118704C (en) 1997-01-21
WO1993006099A1 (en) 1993-04-01
JP2535134B2 (ja) 1996-09-18
EP0607164B1 (en) 2002-05-02
PT100901A (pt) 1994-02-28
CN1071168A (zh) 1993-04-21
NO940927D0 (no) 1994-03-15
ES2174836T3 (es) 2002-11-16
DE69232588D1 (de) 2002-06-06
ZA927370B (en) 1994-03-25
HU9400728D0 (en) 1994-06-28
AU2481292A (en) 1993-04-27
ATE216996T1 (de) 2002-05-15
DE69232588T2 (de) 2002-08-22
BR9206500A (pt) 1995-10-03
EP0607164A1 (en) 1994-07-27
NO940927L (no) 1994-03-15
US5527808A (en) 1996-06-18

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