ATE216996T1 - Kondensierte trizyklische, stickstoffenthaltende verbindungen als substanz p rezeptor antagonisten - Google Patents

Kondensierte trizyklische, stickstoffenthaltende verbindungen als substanz p rezeptor antagonisten

Info

Publication number
ATE216996T1
ATE216996T1 AT92918206T AT92918206T ATE216996T1 AT E216996 T1 ATE216996 T1 AT E216996T1 AT 92918206 T AT92918206 T AT 92918206T AT 92918206 T AT92918206 T AT 92918206T AT E216996 T1 ATE216996 T1 AT E216996T1
Authority
AT
Austria
Prior art keywords
pct
nitrogen containing
substance
containing compounds
receptor antagonists
Prior art date
Application number
AT92918206T
Other languages
English (en)
Inventor
John A Lowe Iii
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Application granted granted Critical
Publication of ATE216996T1 publication Critical patent/ATE216996T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Psychiatry (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
AT92918206T 1991-09-26 1992-08-20 Kondensierte trizyklische, stickstoffenthaltende verbindungen als substanz p rezeptor antagonisten ATE216996T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US76648891A 1991-09-26 1991-09-26
PCT/US1992/006819 WO1993006099A1 (en) 1991-09-16 1992-08-20 Fused tricyclic nitrogen containing heterocycles as substance p receptor antagonists

Publications (1)

Publication Number Publication Date
ATE216996T1 true ATE216996T1 (de) 2002-05-15

Family

ID=25076576

Family Applications (1)

Application Number Title Priority Date Filing Date
AT92918206T ATE216996T1 (de) 1991-09-26 1992-08-20 Kondensierte trizyklische, stickstoffenthaltende verbindungen als substanz p rezeptor antagonisten

Country Status (19)

Country Link
US (1) US5527808A (de)
EP (1) EP0607164B1 (de)
JP (1) JP2535134B2 (de)
CN (1) CN1071168A (de)
AT (1) ATE216996T1 (de)
AU (1) AU2481292A (de)
BR (1) BR9206500A (de)
CA (1) CA2118704C (de)
CZ (1) CZ59394A3 (de)
DE (1) DE69232588T2 (de)
DK (1) DK0607164T3 (de)
ES (1) ES2174836T3 (de)
FI (1) FI941212L (de)
HU (1) HU9400728D0 (de)
MX (1) MX9205242A (de)
NO (1) NO940927D0 (de)
PT (1) PT100901A (de)
WO (1) WO1993006099A1 (de)
ZA (1) ZA927370B (de)

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FR2700472B1 (fr) 1993-01-19 1995-02-17 Rhone Poulenc Rorer Sa Association synergisante ayant un effet antagoniste des récepteurs NK1 et NK2.
US5393762A (en) * 1993-06-04 1995-02-28 Pfizer Inc. Pharmaceutical agents for treatment of emesis
EP0653208A3 (de) * 1993-11-17 1995-10-11 Pfizer Substanz P Antagonisten zur Behandlung oder Verhütung des sonnenbrandes.
EP0659409A3 (de) * 1993-11-23 1995-08-09 Pfizer Substanz P Antagonisten zur Hemmung der Angiogenese.
EP0655246A1 (de) * 1993-11-30 1995-05-31 Pfizer Inc. Substanz P Antagonisten zur Behandlung von durch Helicobacter Pylori oder andere spirale Urease-positive Gram-negative Bakterien verursachten Krankheiten
IL116249A (en) * 1994-12-12 2003-07-06 Pfizer Nk-1 receptor antagonists for the treatment of neuronal damage and stroke
FR2728265A1 (fr) * 1994-12-19 1996-06-21 Oreal Utilisation d'un antagoniste de substance p dans une composition pharmaceutique
FR2728169A1 (fr) * 1994-12-19 1996-06-21 Oreal Utilisation d'un antagoniste de substance p pour le traitement des prurits et des dysesthesies oculaires ou palpebrales
FR2728166A1 (fr) 1994-12-19 1996-06-21 Oreal Composition topique contenant un antagoniste de substance p
FR2728165A1 (fr) 1994-12-19 1996-06-21 Oreal Utilisation d'un antagoniste de substance p pour le traitement des rougeurs cutanees d'origine neurogene
TW458774B (en) 1995-10-20 2001-10-11 Pfizer Antiemetic pharmaceutical compositions
FR2741262B1 (fr) 1995-11-20 1999-03-05 Oreal Utilisation d'un antagoniste de tnf-alpha pour le traitement des rougeurs cutanees d'origine neurogene
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US8691825B2 (en) 2009-04-01 2014-04-08 Merck Sharp & Dohme Corp. Inhibitors of AKT activity
KR101830447B1 (ko) 2009-05-12 2018-02-20 알바니 몰레큘라 리써치, 인크. 7-(［1,2,4］트리아졸로［1,5-α］피리딘-6-일)-4-(3,4-디클로로페닐)-1,2,3,4-테트라하이드로이소퀴놀린 및 이의 용도
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DE69106365T2 (de) * 1990-07-23 1995-05-04 Pfizer Chinuclidinderivate.

Also Published As

Publication number Publication date
DE69232588T2 (de) 2002-08-22
ZA927370B (en) 1994-03-25
FI941212A0 (fi) 1994-03-15
WO1993006099A1 (en) 1993-04-01
CA2118704C (en) 1997-01-21
CN1071168A (zh) 1993-04-21
MX9205242A (es) 1993-03-01
HU9400728D0 (en) 1994-06-28
NO940927L (no) 1994-03-15
US5527808A (en) 1996-06-18
NO940927D0 (no) 1994-03-15
FI941212A7 (fi) 1994-03-15
CA2118704A1 (en) 1993-04-01
JP2535134B2 (ja) 1996-09-18
EP0607164B1 (de) 2002-05-02
ES2174836T3 (es) 2002-11-16
DE69232588D1 (de) 2002-06-06
JPH06507179A (ja) 1994-08-11
FI941212L (fi) 1994-03-15
AU2481292A (en) 1993-04-27
EP0607164A1 (de) 1994-07-27
BR9206500A (pt) 1995-10-03
CZ59394A3 (en) 1994-11-16
PT100901A (pt) 1994-02-28
DK0607164T3 (da) 2002-06-17

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Legal Events

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