FI940866A - Med pH-känsliga utlösare försedda, osmotiska, sönderbristande anordningar för att frigöra ämne - Google Patents

Med pH-känsliga utlösare försedda, osmotiska, sönderbristande anordningar för att frigöra ämne Download PDF

Info

Publication number
FI940866A
FI940866A FI940866A FI940866A FI940866A FI 940866 A FI940866 A FI 940866A FI 940866 A FI940866 A FI 940866A FI 940866 A FI940866 A FI 940866A FI 940866 A FI940866 A FI 940866A
Authority
FI
Finland
Prior art keywords
beneficial agent
osmotic
osmagent
semipermeable membrane
release substance
Prior art date
Application number
FI940866A
Other languages
English (en)
Finnish (fi)
Other versions
FI113941B (sv
FI940866A0 (sv
Inventor
Scott M Herbig
Kelly L Smith
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of FI940866A0 publication Critical patent/FI940866A0/sv
Publication of FI940866A publication Critical patent/FI940866A/sv
Application granted granted Critical
Publication of FI113941B publication Critical patent/FI113941B/sv

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4816Wall or shell material
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0002Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0004Osmotic delivery systems; Sustained release driven by osmosis, thermal energy or gas
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/28Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2886Dragees; Coated pills or tablets, e.g. with film or compression coating having two or more different drug-free coatings; Tablets of the type inert core-drug layer-inactive layer
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • External Artificial Organs (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Detergent Compositions (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
FI940866A 1993-02-25 1994-02-24 Förfarande för framställning av med pH-känsliga utlösare försedda, osmotiska, sönderbristande anordningar för att frigöra ämne FI113941B (sv)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/023,227 US5358502A (en) 1993-02-25 1993-02-25 PH-triggered osmotic bursting delivery devices
US2322793 1993-02-25

Publications (3)

Publication Number Publication Date
FI940866A0 FI940866A0 (sv) 1994-02-24
FI940866A true FI940866A (sv) 1994-08-26
FI113941B FI113941B (sv) 2004-07-15

Family

ID=21813831

Family Applications (1)

Application Number Title Priority Date Filing Date
FI940866A FI113941B (sv) 1993-02-25 1994-02-24 Förfarande för framställning av med pH-känsliga utlösare försedda, osmotiska, sönderbristande anordningar för att frigöra ämne

Country Status (19)

Country Link
US (2) US5358502A (sv)
EP (1) EP0612520B1 (sv)
JP (1) JP2862222B2 (sv)
CN (1) CN1098286A (sv)
AT (1) ATE202927T1 (sv)
AU (1) AU660386B2 (sv)
CA (1) CA2116288C (sv)
DE (1) DE69427664T2 (sv)
DK (1) DK0612520T3 (sv)
ES (1) ES2157953T3 (sv)
FI (1) FI113941B (sv)
GR (1) GR3036497T3 (sv)
IL (1) IL108691A0 (sv)
MX (1) MX9401396A (sv)
NO (1) NO312123B1 (sv)
NZ (1) NZ250967A (sv)
PT (1) PT612520E (sv)
TW (1) TW283641B (sv)
ZA (1) ZA941262B (sv)

Families Citing this family (71)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2723536A1 (fr) * 1994-08-11 1996-02-16 Seth Pawan Composition permettant une liberation selective d'un principe actif
US5800422A (en) * 1995-06-02 1998-09-01 Alza Corporation Osmotic device with delayed activation of drug delivery and complete drug release
US5902605A (en) * 1996-04-18 1999-05-11 Alza Corporation Drug delivery device with minimal residual drug retention
JP3950175B2 (ja) * 1997-05-30 2007-07-25 オスモティカ・コーポレイション 多層浸透デバイス
US7772455B1 (en) 1997-11-14 2010-08-10 The Procter & Gamble Company Disposable article providing improved management of bodily exudates
US6186991B1 (en) 1998-06-29 2001-02-13 The Procter & Gamble Company Disposable article having a responsive system including a mechanical actuator
US6149636A (en) * 1998-06-29 2000-11-21 The Procter & Gamble Company Disposable article having proactive sensors
US5916595A (en) * 1997-12-12 1999-06-29 Andrx Pharmaceutials, Inc. HMG co-reductase inhibitor
JP2002500201A (ja) * 1998-01-05 2002-01-08 ユニバーシティ オブ ワシントン 膜破壊剤を使用する増強された輸送
US6660301B1 (en) * 1998-03-06 2003-12-09 Biosphere Medical, Inc. Injectable microspheres for dermal augmentation and tissue bulking
US6359190B1 (en) 1998-06-29 2002-03-19 The Procter & Gamble Company Device for measuring the volume of a body cavity
US6342037B1 (en) 1998-06-29 2002-01-29 The Procter & Gamble Company Device having fecal component sensor
US6160198A (en) * 1998-06-29 2000-12-12 The Procter & Gamble Company Disposable article having a discontinuous responsive system
DE69913347T2 (de) 1998-06-29 2004-10-21 Procter & Gamble Exkrementveränderndes mittel enthaltende windel
EP1091720B1 (en) 1998-06-29 2004-05-19 The Procter & Gamble Company Disposable absorbent article having a responsive system including an electrical actuator
US6433244B1 (en) 1998-06-29 2002-08-13 The Procter & Gamble Company Disposable treatment article having a responsive system
WO2000000082A1 (en) 1998-06-29 2000-01-06 The Procter & Gamble Company Disposable article having proactive sensor
US6372951B1 (en) 1998-06-29 2002-04-16 The Procter & Gamble Company Disposable article having sensor to detect impending elimination of bodily waste
EP1091718B1 (en) 1998-06-29 2007-09-05 The Procter & Gamble Company Disposable treatment article having a responsive system
US6531152B1 (en) 1998-09-30 2003-03-11 Dexcel Pharma Technologies Ltd. Immediate release gastrointestinal drug delivery system
US6632451B2 (en) 1999-06-04 2003-10-14 Dexcel Pharma Technologies Ltd. Delayed total release two pulse gastrointestinal drug delivery system
GB9923045D0 (en) * 1999-09-29 1999-12-01 Novartis Ag New oral formulations
WO2001051092A2 (en) * 2000-01-07 2001-07-19 University Of Washington Enhanced transport of agents using membrane disruptive agents
AU2001249221A1 (en) 2000-03-20 2001-10-03 Biosphere Medical, Inc. Injectable and swellable microspheres for tissue bulking
HUP0203451A3 (en) * 2000-08-09 2004-05-28 Panacea Biotec Ltd Pharmaceutical compositions of anti-tubercular drugs and process for their preparation
GB2369997B (en) * 2000-12-12 2004-08-11 Johnson & Johnson Medical Ltd Dressings for the treatment of exuding wounds
DE10100689A1 (de) * 2001-01-09 2002-07-18 Henkel Kgaa Wasch- und reinigungsaktive Substanzen enthaltende Mikrokapseln
CA2409552A1 (en) * 2001-10-25 2003-04-25 Depomed, Inc. Gastric retentive oral dosage form with restricted drug release in the lower gastrointestinal tract
US20030104052A1 (en) * 2001-10-25 2003-06-05 Bret Berner Gastric retentive oral dosage form with restricted drug release in the lower gastrointestinal tract
US20030152622A1 (en) * 2001-10-25 2003-08-14 Jenny Louie-Helm Formulation of an erodible, gastric retentive oral diuretic
US20030091630A1 (en) * 2001-10-25 2003-05-15 Jenny Louie-Helm Formulation of an erodible, gastric retentive oral dosage form using in vitro disintegration test data
EP1530505A4 (en) * 2001-11-30 2007-09-12 Bristol Myers Squibb Co CONFIGURATIONS OF PIPETTES AND PIPETTE SETS FOR MEASURING CELLULAR ELECTRICAL PROPERTIES
DE10209979A1 (de) * 2002-03-07 2003-09-25 Ratiopharm Gmbh Arzneimittel mit Cholesterolspiegel-senkenden Wirkstoffen mit zeitverzögerter Wirkstofffreisetzung
US20040062778A1 (en) * 2002-09-26 2004-04-01 Adi Shefer Surface dissolution and/or bulk erosion controlled release compositions and devices
US7670627B2 (en) * 2002-12-09 2010-03-02 Salvona Ip Llc pH triggered targeted controlled release systems for the delivery of pharmaceutical active ingredients
US20040143221A1 (en) * 2002-12-27 2004-07-22 Shadduck John H. Biomedical implant for sustained agent release
TWI355276B (en) * 2003-01-14 2012-01-01 Akira Tsuji Gastrointestinal absorption enhancer mediated by p
US8029822B2 (en) * 2003-05-22 2011-10-04 Osmotica Kereskedelmi és Seolgáltató KFT Rupturing controlled release device having a preformed passageway
US20060177507A1 (en) * 2003-05-22 2006-08-10 Joaquina Faour Controlled release device containing lercanidipine
US20050139805A1 (en) * 2003-11-06 2005-06-30 Dale Koster Dechlorinating tablet and method of manufacture
US20040224019A1 (en) * 2004-03-03 2004-11-11 Adi Shefer Oral controlled release system for targeted drug delivery into the cell and its nucleus for gene therapy, DNA vaccination, and administration of gene based drugs
CA2561174A1 (en) * 2004-03-26 2005-10-20 The University Of Utah Research Foundation Bioresponsive polymer system for delivery of microbicides
EP1991864B1 (en) * 2006-02-28 2018-03-21 F.Hoffmann-La Roche Ag Method for assessing absorption properties of low solubility compounds
WO2007109584A1 (en) * 2006-03-16 2007-09-27 University Of Washington Temperature-and ph-responsive polymer compositions
CN101534795B (zh) 2006-11-21 2013-04-03 麦克内尔-Ppc股份有限公司 改进释放的镇痛悬浮液
US7981688B2 (en) 2007-03-08 2011-07-19 University Of Washington Stimuli-responsive magnetic nanoparticles and related methods
MX354786B (es) 2007-06-04 2018-03-21 Synergy Pharmaceuticals Inc Agonistas de guanilato ciclasa utiles para el tratamiento de trastornos gastrointestinales, inflamacion, cancer y otros trastornos.
US8969514B2 (en) 2007-06-04 2015-03-03 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
US9833510B2 (en) * 2007-06-12 2017-12-05 Johnson & Johnson Consumer Inc. Modified release solid or semi-solid dosage forms
WO2009028583A1 (ja) * 2007-08-29 2009-03-05 Shionogi & Co., Ltd. コーティング製剤の製造方法
CA2726917C (en) 2008-06-04 2018-06-26 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
WO2010009319A2 (en) 2008-07-16 2010-01-21 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal, inflammation, cancer and other disorders
WO2010042203A1 (en) * 2008-10-10 2010-04-15 Alvine Pharmaceuticals, Inc. Dosage forms that facilitate rapid activation of zymogen
US8426214B2 (en) * 2009-06-12 2013-04-23 University Of Washington System and method for magnetically concentrating and detecting biomarkers
WO2011008534A1 (en) * 2009-06-30 2011-01-20 Boston Scientific Scimed, Inc. Implantable self-powered biodegradable medical device to treat or prevent reperfusion injury
WO2011039686A1 (en) 2009-09-30 2011-04-07 Pfizer Inc. Latrepirdine oral sustained release dosage forms
US9080933B2 (en) 2009-11-09 2015-07-14 University Of Washington Through Its Center For Commercialization Stimuli-responsive polymer diagnostic assay comprising magnetic nanoparticles and capture conjugates
US20110117668A1 (en) * 2009-11-09 2011-05-19 University Of Washington Through Its Center For Commercialization Self-powered smart diagnostic devices
CN102892713B (zh) 2010-02-10 2016-05-04 金斯顿女王大学 具有可转换的离子强度的水
US9616097B2 (en) 2010-09-15 2017-04-11 Synergy Pharmaceuticals, Inc. Formulations of guanylate cyclase C agonists and methods of use
CN103459439B (zh) * 2010-12-15 2017-09-12 金斯顿女王大学 使用具有可转换的离子强度的水的系统和方法
US9545446B2 (en) 2013-02-25 2017-01-17 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase and their uses
WO2014151200A2 (en) 2013-03-15 2014-09-25 Synergy Pharmaceuticals Inc. Compositions useful for the treatment of gastrointestinal disorders
EP2970384A1 (en) 2013-03-15 2016-01-20 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase and their uses
JP6041823B2 (ja) 2013-03-16 2016-12-14 ファイザー・インク トファシチニブの経口持続放出剤形
US20160220630A1 (en) 2013-10-10 2016-08-04 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase useful for the treatment of opioid induced dysfunctions
US20160060589A1 (en) * 2014-09-01 2016-03-03 Abnova (Taiwan) Corporation Particle transporting system and method of operating the same
US20190307912A1 (en) * 2015-10-20 2019-10-10 Takasago International Corporation Fragrance delivery device, system, and method
JP6944822B2 (ja) * 2017-06-27 2021-10-06 持田製薬株式会社 易服用性カプセル
WO2021014360A1 (en) 2019-07-23 2021-01-28 Pfizer Inc. Oral modified release dosage forms
KR20220101150A (ko) 2019-11-14 2022-07-19 화이자 인코포레이티드 1-(((2s,3s,4s)-3-에틸-4-플루오로-5-옥소피롤리딘-2-일)메톡시)-7-메톡시이소퀴놀린-6-카복사마이드 조합물 및 경구 투여 형태

Family Cites Families (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3247066A (en) * 1962-09-12 1966-04-19 Parke Davis & Co Controlled release dosage form containing water-swellable beadlet
US4177256A (en) * 1973-04-25 1979-12-04 Alza Corporation Osmotic bursting drug delivery device
US4142526A (en) * 1974-12-23 1979-03-06 Alza Corporation Osmotic releasing system with means for changing release therefrom
US3952741A (en) * 1975-01-09 1976-04-27 Bend Research Inc. Controlled release delivery system by an osmotic bursting mechanism
US4016880A (en) * 1976-03-04 1977-04-12 Alza Corporation Osmotically driven active agent dispenser
FR2471186A1 (fr) * 1979-12-10 1981-06-19 Roussel Uclaf Nouveaux comprimes a delitescence colique, ainsi que leur procede de preparation
US4539199A (en) * 1981-01-14 1985-09-03 Egyt Gyogyszervegyeszeti Gyar Sustained release pharmaceutical compositions
US4522625A (en) * 1982-09-29 1985-06-11 Alza Corporation Drug dispenser comprising wall formed of semipermeable member and enteric member
DE3243710A1 (de) * 1982-11-25 1984-05-30 Delma, elektro- und medizinische Apparatebau GmbH, 7200 Tuttlingen Operationsleuchte
US4851231A (en) * 1982-12-13 1989-07-25 Alza Corporation System for delivering drug in selected environment of use
US4681583A (en) * 1982-12-20 1987-07-21 Alza Corporation System for dispersing drug in biological environment
US4773907A (en) * 1982-12-20 1988-09-27 Alza Corporation Primary delivery system comprising secondary dosage form
US4578075A (en) * 1982-12-20 1986-03-25 Alza Corporation Delivery system housing a plurality of delivery devices
US4503030A (en) * 1983-06-06 1985-03-05 Alza Corporation Device for delivering drug to certain pH environments
US4587117A (en) * 1983-06-06 1986-05-06 Alza Corporation Medical device for delivering drug to pH environments greater than 3.5
US4627850A (en) * 1983-11-02 1986-12-09 Alza Corporation Osmotic capsule
SE457505B (sv) * 1984-01-10 1989-01-09 Lejus Medical Ab Laminatbelagd oral farmaceutisk komposition och foerfarande foer dess framstaellning
US4705515A (en) * 1984-10-26 1987-11-10 Alza Corporation Dosage form for administering drug of the colon
US4693895A (en) * 1984-10-26 1987-09-15 Alza Corporation Colon delivery system
US4627851A (en) * 1984-10-26 1986-12-09 Alza Corporation Colonic-therapeutic delivery system
GB8518301D0 (en) * 1985-07-19 1985-08-29 Fujisawa Pharmaceutical Co Hydrodynamically explosive systems
IL77186A0 (en) * 1985-11-29 1986-04-29 Touitou Elka Pharmaceutical insulin composition
SE460945B (sv) * 1987-01-15 1989-12-11 Lejus Medical Ab En multipel-unit-dos komposition av furosemid
US4830855A (en) * 1987-11-13 1989-05-16 Landec Labs, Inc. Temperature-controlled active agent dispenser
US4904474A (en) * 1988-01-25 1990-02-27 Alza Corporation Delivery of drug to colon by oral disage form
US5472710A (en) * 1988-04-16 1995-12-05 Schwarz Pharma Ag Pharmaceutical preparation to be administered orally with controlled release of active substance and method for its manufacture
JP2792862B2 (ja) * 1988-07-30 1998-09-03 寛治 高田 経口腸溶製剤
IL91398A (en) * 1988-08-30 1994-05-30 Pfizer A device for the controlled release of pneumatic substances, including the active substance, surrounded by an asymmetric membrane
EP0408496A3 (en) * 1989-07-12 1992-07-01 Ciba-Geigy Ag Solid dosage form for pharmaceutical substances
US5178866A (en) * 1990-03-23 1993-01-12 Alza Corporation Dosage form for delivering drug to the intestine
ATE112163T1 (de) * 1991-01-03 1994-10-15 Glaxo Canada Verfahren zur herstellung einer festem pharmazeutischen zusammensetzung.
US5443459A (en) * 1991-01-30 1995-08-22 Alza Corporation Osmotic device for delayed delivery of agent
NZ286242A (en) * 1991-03-26 1997-11-24 Csl Ltd Use of veterinary implant as a single dose vaccination system: rupturable polymer film coating around core of active agent and water soluble excipient
US5364634A (en) * 1991-11-08 1994-11-15 Southwest Research Institute Controlled-release PH sensitive capsule and adhesive system and method

Also Published As

Publication number Publication date
JPH072645A (ja) 1995-01-06
GR3036497T3 (en) 2001-11-30
NZ250967A (en) 1996-02-27
FI113941B (sv) 2004-07-15
ES2157953T3 (es) 2001-09-01
AU5640094A (en) 1994-09-22
FI940866A0 (sv) 1994-02-24
IL108691A0 (en) 1994-05-30
DE69427664T2 (de) 2001-10-25
EP0612520A3 (en) 1995-11-15
DE69427664D1 (de) 2001-08-16
JP2862222B2 (ja) 1999-03-03
AU660386B2 (en) 1995-06-22
DK0612520T3 (da) 2001-09-17
NO312123B1 (no) 2002-03-25
EP0612520B1 (en) 2001-07-11
CA2116288A1 (en) 1994-08-26
NO940642D0 (no) 1994-02-24
PT612520E (pt) 2001-12-28
TW283641B (sv) 1996-08-21
ZA941262B (en) 1995-08-24
US5609590A (en) 1997-03-11
EP0612520A2 (en) 1994-08-31
MX9401396A (es) 1994-08-31
US5358502A (en) 1994-10-25
NO940642L (no) 1994-08-26
CN1098286A (zh) 1995-02-08
CA2116288C (en) 1997-11-18
ATE202927T1 (de) 2001-07-15

Similar Documents

Publication Publication Date Title
FI940866A (sv) Med pH-känsliga utlösare försedda, osmotiska, sönderbristande anordningar för att frigöra ämne
DE69208104D1 (de) Orale, osmotische vorrichtung
ES551505A0 (es) Un sistema osmotico lipidico para dispersar agentes farmacologicamente activos.
BE899464A (fr) Composition a liberation soutenue de propanolol.
DE60004491D1 (de) Steuerung von kontrastverbesserter bildgebung
ES2130423T3 (es) Sistema de administracion intravaginal.
ATE196077T1 (de) Osmotische vorrichtung mit dampfdurchlaessiger beschichtung
DE69322286D1 (de) Verabreichungsvorrichtungen mit gestützten flüssigen membranen
IE851524L (en) Osmotically active system for dispensing drugs
IE882898L (en) Solubility modulated drug delivery device
ES2022984B3 (es) Dispositivo para deshidratacion controlada por absorcion de agua.
AR000076A1 (es) Formulación de polvo humectable, dispersion acuosade dicha formulación de polvo humectable, proce so para preparar dicha formulacion, metodo para administar dicha dispersion acuosa y metodo para el tratamiento de post-emergencia de malezas objetivoen un cultivo con dicha dispersion acuosa.
GR3005132T3 (sv)
ES2078516T3 (es) Sistema portatil de purificacion de agua.
JPS5519232A (en) Preparation of slow-releasing capsule containing physiologically active substance
ITBO970017U1 (it) Il trotatore componibile e variabile x 12

Legal Events

Date Code Title Description
MA Patent expired