FI940656A7 - Uusia syklisiä ureoita, jotka ovat käyttökelpoisia sydämen rytmihäiriöiden ja värinän vastaisina aineina - Google Patents

Uusia syklisiä ureoita, jotka ovat käyttökelpoisia sydämen rytmihäiriöiden ja värinän vastaisina aineina Download PDF

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Publication number
FI940656A7
FI940656A7 FI940656A FI940656A FI940656A7 FI 940656 A7 FI940656 A7 FI 940656A7 FI 940656 A FI940656 A FI 940656A FI 940656 A FI940656 A FI 940656A FI 940656 A7 FI940656 A7 FI 940656A7
Authority
FI
Finland
Prior art keywords
antifibrillating
antiarrhythmic
agents
cyclic ureas
new cyclic
Prior art date
Application number
FI940656A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI940656A0 (fi
Inventor
Jr Stanford Salvatore Pelosi
Chia-Nien Yu
Original Assignee
Procter & Gamble Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Procter & Gamble Pharma filed Critical Procter & Gamble Pharma
Publication of FI940656A0 publication Critical patent/FI940656A0/fi
Publication of FI940656A7 publication Critical patent/FI940656A7/fi

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Cardiology (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Hydrogenated Pyridines (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Furan Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
FI940656A 1991-08-14 1994-02-11 Uusia syklisiä ureoita, jotka ovat käyttökelpoisia sydämen rytmihäiriöiden ja värinän vastaisina aineina FI940656A7 (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US74486491A 1991-08-14 1991-08-14
PCT/US1992/006683 WO1993004060A1 (en) 1991-08-14 1992-08-10 Novel cyclic ureas useful as antiarrhythmic and antifibrillatory agents

Publications (2)

Publication Number Publication Date
FI940656A0 FI940656A0 (fi) 1994-02-11
FI940656A7 true FI940656A7 (fi) 1994-02-11

Family

ID=24994265

Family Applications (1)

Application Number Title Priority Date Filing Date
FI940656A FI940656A7 (fi) 1991-08-14 1994-02-11 Uusia syklisiä ureoita, jotka ovat käyttökelpoisia sydämen rytmihäiriöiden ja värinän vastaisina aineina

Country Status (24)

Country Link
US (1) US5691369A (cs)
EP (2) EP0891976B1 (cs)
JP (1) JPH06509803A (cs)
AT (2) ATE226202T1 (cs)
AU (1) AU665209B2 (cs)
BR (1) BR9206371A (cs)
CA (1) CA2115426C (cs)
CZ (1) CZ286265B6 (cs)
DE (2) DE69232825D1 (cs)
DK (1) DK0598046T3 (cs)
ES (1) ES2132127T3 (cs)
FI (1) FI940656A7 (cs)
GR (1) GR3030579T3 (cs)
HU (1) HUT70029A (cs)
IL (1) IL102792A (cs)
MX (1) MX9204735A (cs)
MY (1) MY109528A (cs)
NO (1) NO305285B1 (cs)
NZ (1) NZ243937A (cs)
PL (1) PL170960B1 (cs)
PT (1) PT100776B (cs)
RU (1) RU2142461C1 (cs)
SK (1) SK279677B6 (cs)
WO (1) WO1993004060A1 (cs)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL170984B1 (pl) * 1991-08-14 1997-02-28 Procter & Gamble Pharma Sposób wytwarzania nowych 4-oksycyklicznych pochodnych mocznika PL PL PL
US6083945A (en) * 1995-06-07 2000-07-04 The Procter & Gamble Company Cyclic ureas useful as antiarrhythmic and antifibrillatory agents
KR100381213B1 (ko) * 1998-03-26 2003-08-14 주식회사 엘지생명과학 파네실전이효소억제능을갖는사이클릭우레아유도체및그의제조방법
AU745697B2 (en) * 1998-09-08 2002-03-28 Smithkline Beecham Corporation Lipstatin derivative-soluble fiber tablets
IL148291A0 (en) * 1999-09-16 2002-09-12 Tanabe Seiyaku Co Aromatic nitrogen-containing 6-membered cyclic compounds
US6288151B1 (en) * 1999-10-14 2001-09-11 Air Products And Chemicals, Inc. Alkylated aminoalkyl cyclic urea surfactants
SE0100733D0 (sv) * 2001-03-05 2001-03-05 Medivir Ab Non-nucleoside reverse transcriptase inhibitors
US7129359B2 (en) 2002-07-09 2006-10-31 National Health Research Institutes Imidazolidinone compounds
US7259174B2 (en) 2004-05-25 2007-08-21 National Health Research Institutes Imidazolidinone compounds

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2776979A (en) * 1956-04-05 1957-01-08 Norwich Pharma Co 1-nitroso-2-imidazolidone and process
NL257071A (cs) * 1959-10-23
US3254075A (en) * 1963-08-28 1966-05-31 Norwich Pharma Co 1-(2-hydroxyethyl and 2-haloethyl-3-(5-nitrofurfurylideneamino)-2-imidazolidinones
US3415821A (en) * 1965-09-07 1968-12-10 Norwich Pharma Co 1-(5-substituted)furfurylideneamino hydantoins and imidazolidinones
US3407195A (en) * 1967-04-03 1968-10-22 Norwich Pharma Co 4-methyl-1-(5-nitrofurfurylideneamino)-2-imidazolidinone
DE2335144A1 (de) * 1973-07-07 1975-01-23 Schering Ag Basisch substituierte nitroimidazolmethylenamino-imidazolidinone
JPS5671074A (en) * 1979-11-12 1981-06-13 Takeda Chem Ind Ltd 1,2-disubstituted-4-halogenoimidazole-5-acetic acid derivative
US4775670A (en) * 1980-09-29 1988-10-04 E. R. Squibb & Sons, Inc. 2-oxo-1-azetidinesulfonic acid salts
US4393204A (en) * 1982-05-21 1983-07-12 Norwich Eaton Pharmaceuticals, Inc. 3-[[5-(4-Chlorophenyl)furfurylidene]amino]-5-(substituted)-2-oxazolidinones
US4543359A (en) * 1982-10-01 1985-09-24 Eaton Laboratories, Inc. Treating cardiac arrhythmias with dantrolene sodium
US4705799A (en) * 1983-06-07 1987-11-10 E. I. Du Pont De Nemours And Company Aminomethyl oxooxazolidinyl benzenes useful as antibacterial agents
US4581370A (en) * 1983-07-12 1986-04-08 Schering A.G. Antiarrhythmic imidazoliums
US4720580A (en) * 1984-09-21 1988-01-19 American Home Products Corporation N-(aminoalkylene)benzenesulfonamides
US4707499A (en) * 1985-12-02 1987-11-17 G. D. Searle & Co. 3-alkyl-5-(substituted amino)methyl)dihydro-3-phenyl-2(3H)-furanones and imino analogs thereof used for treatment of arrhythmia
PH23283A (en) * 1986-02-26 1989-06-30 Eisai Co Ltd Piperidine derivative, pharmaceutical composition containing the same and method of use thereof
US4783443A (en) * 1986-03-03 1988-11-08 The University Of Chicago Amino acyl cephalosporin derivatives
US4713832A (en) * 1986-04-11 1987-12-15 Ampex Corporation Programmable divider up/down counter with anti-aliasing feature and asynchronous read/write
US4870095A (en) * 1988-06-13 1989-09-26 Sterling Drug, Inc. 1H-pyrazole-1-alkanamides, antiarrhythmic compositions and use
EP0347733A1 (en) * 1988-06-20 1989-12-27 Eisai Co., Ltd. Optically active hydantoin derivatives
US5137905A (en) * 1988-10-27 1992-08-11 The Upjohn Company Heterocyclic acetylenic amines having central nervous system activity
US4966967A (en) * 1989-09-15 1990-10-30 Berlex Laboratories, Inc. 3,4,5,6-tetrahydro-2H-1,7,4-benzodioxazonines as cardiovascular agents
US5032598A (en) * 1989-12-08 1991-07-16 Merck & Co., Inc. Nitrogens containing heterocyclic compounds as class III antiarrhythmic agents
US4963561A (en) * 1990-02-28 1990-10-16 Sterling Drug Inc. Imidazopyridines, their preparation and use
FR2678272B1 (fr) * 1991-06-27 1994-01-14 Synthelabo Derives de 2-aminopyrimidine-4-carboxamide, leur preparation et leur application en therapeutique.
RU2125568C1 (ru) * 1991-08-14 1999-01-27 Проктер энд Гэмбл Фармасьютикалз, Инк. Соединения циклического уретана или их фармацевтически приемлемые соли, способ лечения людей и других млекопитающих, страдающих сердечной аритмией и/или сердечной фибрилляцией, фармацевтическая композиция для лечения аритмии и фибрилляции

Also Published As

Publication number Publication date
DK0598046T3 (da) 1999-05-25
DE69228751D1 (de) 1999-04-29
HU9400391D0 (en) 1994-05-30
MX9204735A (es) 1994-03-31
ES2132127T3 (es) 1999-08-16
BR9206371A (pt) 1995-10-17
CZ286265B6 (cs) 2000-03-15
EP0598046B1 (en) 1999-03-24
AU2460092A (en) 1993-03-16
SK17094A3 (en) 1995-02-08
JPH06509803A (ja) 1994-11-02
NO940498D0 (no) 1994-02-14
US5691369A (en) 1997-11-25
WO1993004060A1 (en) 1993-03-04
SK279677B6 (sk) 1999-02-11
EP0891976B1 (en) 2002-10-16
NO305285B1 (no) 1999-05-03
EP0891976A1 (en) 1999-01-20
CA2115426C (en) 2001-09-11
ATE226202T1 (de) 2002-11-15
CA2115426A1 (en) 1993-03-04
PT100776B (pt) 1999-07-30
ATE178063T1 (de) 1999-04-15
CZ30594A3 (en) 1994-12-15
IL102792A0 (en) 1993-01-31
PL170960B1 (pl) 1997-02-28
PT100776A (pt) 1993-12-31
MY109528A (en) 1997-02-28
RU2142461C1 (ru) 1999-12-10
FI940656A0 (fi) 1994-02-11
HUT70029A (en) 1995-09-28
DE69232825D1 (de) 2002-11-21
NO940498L (no) 1994-02-14
IL102792A (en) 1997-01-10
DE69228751T2 (de) 1999-10-07
NZ243937A (en) 1996-10-28
EP0598046A1 (en) 1994-05-25
GR3030579T3 (en) 1999-10-29
AU665209B2 (en) 1995-12-21

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