FI934710A - 4-aryl-3-(heteroarylureido)kinolinderivat - Google Patents

4-aryl-3-(heteroarylureido)kinolinderivat Download PDF

Info

Publication number
FI934710A
FI934710A FI934710A FI934710A FI934710A FI 934710 A FI934710 A FI 934710A FI 934710 A FI934710 A FI 934710A FI 934710 A FI934710 A FI 934710A FI 934710 A FI934710 A FI 934710A
Authority
FI
Finland
Prior art keywords
kinolinderivat
heteroarylureido
aryl
Prior art date
Application number
FI934710A
Other languages
English (en)
Finnish (fi)
Other versions
FI934710A0 (fi
Inventor
Ernest S Hamanaka
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of FI934710A publication Critical patent/FI934710A/fi
Publication of FI934710A0 publication Critical patent/FI934710A0/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38—Nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/36—Sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
FI934710A 1991-04-26 1993-10-25 4-aryl-3-(heteroarylureido)kinolinderivat FI934710A0 (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US69232391A 1991-04-26 1991-04-26
PCT/US1992/001801 WO1992019614A1 (en) 1991-04-26 1992-03-16 4-aryl-3-(heteroarylureido)quinoline derivatives

Publications (2)

Publication Number Publication Date
FI934710A true FI934710A (fi) 1993-10-25
FI934710A0 FI934710A0 (fi) 1993-10-25

Family

ID=24780107

Family Applications (1)

Application Number Title Priority Date Filing Date
FI934710A FI934710A0 (fi) 1991-04-26 1993-10-25 4-aryl-3-(heteroarylureido)kinolinderivat

Country Status (20)

Country Link
EP (1) EP0590094A1 (zh)
JP (1) JPH0776215B2 (zh)
CN (1) CN1066068A (zh)
AU (1) AU1879792A (zh)
BR (1) BR9205939A (zh)
CA (1) CA2108014A1 (zh)
CZ (1) CZ395592A3 (zh)
DE (1) DE9290049U1 (zh)
FI (1) FI934710A0 (zh)
HU (1) HUT65748A (zh)
IE (1) IE921330A1 (zh)
IL (1) IL101627A0 (zh)
MX (1) MX9201916A (zh)
NO (1) NO933837L (zh)
NZ (1) NZ242493A (zh)
PT (1) PT100426A (zh)
TW (1) TW197436B (zh)
WO (1) WO1992019614A1 (zh)
YU (1) YU44592A (zh)
ZA (1) ZA922976B (zh)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2125325T3 (es) * 1992-01-23 1999-03-01 Pfizer Derivados de 4-fenil-3-(heteroarilureido)-1,2-dihidro-2-oxoquinolina como agentes antihipercolesterolemicos y antiateroscleroticos.
US5565472A (en) * 1992-12-21 1996-10-15 Pfizer Inc. 4-aryl-3-(heteroarylureido)-1,2-dihydro-2-oxo-quinoline derivatives as antihypercholesterolemic and antiatherosclerotic agents
NZ264063A (en) * 1993-08-13 1995-11-27 Nihon Nohyaku Co Ltd N-(2-phenylpyrid-3-yl)- and n-(4-phenylpyrimidin-5-yl)-n'-phenylurea derivatives and pharmaceutical compositions
US5843957A (en) * 1995-05-19 1998-12-01 Sumitomo Pharmaceuticals Company, Ltd. Naphthyridine derivatives
NZ308228A (en) * 1995-05-31 1999-11-29 Sumitomo Pharma Substituted 1,8-naphthyridine derivatives
NZ335766A (en) * 1996-11-26 2000-11-24 Sumitomo Pharma Naphthyridine derivatives and use as acyl-CoA cholesterol acyl transferase(ACAT) inhibitor as treatment of hyperlipidemia
AU2547399A (en) 1998-02-25 1999-09-15 Sumitomo Pharmaceuticals Company, Limited Pyridone derivatives and process for producing the same
US6452008B2 (en) 1998-02-25 2002-09-17 Sumitomo Pharmaceuticals Company, Limited Pyridone derivatives and process for preparing the same
BRPI0417543A (pt) * 2003-12-12 2007-03-27 Wyeth Corp quinolinas úteis no tratamento de doença cardiovascular
CN103601677B (zh) * 2013-11-19 2015-11-18 清华大学 制备2-烷硫基喹啉衍生物的方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE892088L (en) * 1988-07-12 1990-01-12 William Henry Deryk Morris Quinoline derivatives, their production and use
MX22406A (es) * 1989-09-15 1994-01-31 Pfizer Nuevos derivados de n-aril y n-heteroarilamidas y urea como inhibidores de acil coenzima a: acil transferasa del colesterol (acat).
TW205037B (zh) * 1989-10-06 1993-05-01 Takeda Pharm Industry Co Ltd

Also Published As

Publication number Publication date
HUT65748A (en) 1994-07-28
TW197436B (zh) 1993-01-01
CA2108014A1 (en) 1992-10-27
HU9303025D0 (en) 1994-01-28
JPH0776215B2 (ja) 1995-08-16
PT100426A (pt) 1993-08-31
NO933837L (no) 1993-10-25
AU1879792A (en) 1992-12-21
BR9205939A (pt) 1994-09-27
NZ242493A (en) 1994-08-26
IL101627A0 (en) 1992-12-30
ZA922976B (en) 1993-10-25
CN1066068A (zh) 1992-11-11
FI934710A0 (fi) 1993-10-25
YU44592A (sh) 1994-12-28
MX9201916A (es) 1992-11-01
WO1992019614A1 (en) 1992-11-12
IE921330A1 (en) 1992-11-04
EP0590094A1 (en) 1994-04-06
JPH06501025A (ja) 1994-01-27
DE9290049U1 (de) 1994-01-05
CZ395592A3 (en) 1994-02-16

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