FI934565A0 - Pyrimidinderivat foer att oeka antitumoeraktiviteten - Google Patents

Pyrimidinderivat foer att oeka antitumoeraktiviteten

Info

Publication number
FI934565A0
FI934565A0 FI934565A FI934565A FI934565A0 FI 934565 A0 FI934565 A0 FI 934565A0 FI 934565 A FI934565 A FI 934565A FI 934565 A FI934565 A FI 934565A FI 934565 A0 FI934565 A0 FI 934565A0
Authority
FI
Finland
Prior art keywords
derivatives
oeka
antitumo
pyrimides
activities
Prior art date
Application number
FI934565A
Other languages
English (en)
Finnish (fi)
Other versions
FI934565A (fi
Inventor
Jotham Wadsworth Coe
Anton Franz J Fliri
Takushi Kaneko
Eric Robert Larson
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of FI934565A0 publication Critical patent/FI934565A0/fi
Publication of FI934565A publication Critical patent/FI934565A/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/48Two nitrogen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
FI934565A 1991-04-17 1993-10-15 Pyrimidinderivat foer att oeka antitumoeraktiviteten FI934565A (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US68689991A 1991-04-17 1991-04-17
PCT/US1992/002434 WO1992018498A1 (en) 1991-04-17 1992-03-30 Pyrimidine derivatives for enhancing antitumor activity

Publications (2)

Publication Number Publication Date
FI934565A0 true FI934565A0 (fi) 1993-10-15
FI934565A FI934565A (fi) 1993-10-15

Family

ID=24758194

Family Applications (1)

Application Number Title Priority Date Filing Date
FI934565A FI934565A (fi) 1991-04-17 1993-10-15 Pyrimidinderivat foer att oeka antitumoeraktiviteten

Country Status (22)

Country Link
EP (1) EP0580753B1 (es)
JP (1) JPH0819121B2 (es)
CN (1) CN1065863A (es)
AT (1) ATE119157T1 (es)
AU (1) AU653601B2 (es)
BR (1) BR9205906A (es)
CA (1) CA2108561A1 (es)
CZ (1) CZ390992A3 (es)
DE (2) DE9290039U1 (es)
DK (1) DK0580753T3 (es)
ES (1) ES2068714T3 (es)
FI (1) FI934565A (es)
GR (1) GR3015921T3 (es)
HU (1) HUT65177A (es)
IE (1) IE64915B1 (es)
MX (1) MX9201763A (es)
NO (1) NO933722L (es)
NZ (1) NZ242390A (es)
PT (1) PT100386A (es)
WO (1) WO1992018498A1 (es)
YU (1) YU39992A (es)
ZA (1) ZA922815B (es)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IN188411B (es) * 1997-03-27 2002-09-21 Yuhan Corp
US6440965B1 (en) 1997-10-15 2002-08-27 Krenitsky Pharmaceuticals, Inc. Substituted pyrimidine derivatives, their preparation and their use in the treatment of neurodegenerative or neurological disorders of the central nervous system
KR100272471B1 (ko) 1998-11-17 2000-11-15 김선진 신규의 피리미딘 유도체 및 그의 제조방법
JP2003521468A (ja) 1999-03-17 2003-07-15 シグナル ファーマシューティカルズ, インコーポレイテッド エストロゲンレセプタを変調させるための化合物及び方法
US6593322B1 (en) 1999-03-17 2003-07-15 Signal Pharmaceuticals, Inc. Compounds and methods for modulation of estrogen receptors
US6583148B1 (en) 1999-04-08 2003-06-24 Krenitsky Pharmaceuticals, Inc. Neurotrophic substituted pyrimidines
US6630469B2 (en) * 2000-05-09 2003-10-07 Bristol-Myers Squibb Company 5-HT7 receptor antagonists
ES2346513T3 (es) 2000-07-24 2010-10-18 Krenitsky Pharmaceuticals, Inc. 5-alquinil pirimidinas sustituidas que tienen actividad neurotrofica.
JP2005232081A (ja) * 2004-02-19 2005-09-02 Bayer Cropscience Ag ベンジルピリミジン誘導体の農園芸用殺菌剤としての利用
JP2010111702A (ja) 2009-02-16 2010-05-20 Tetsuya Nishio 複素環化合物、その製造法および用途
CN103333119A (zh) * 2013-05-28 2013-10-02 中国药科大学 1,2-二氢-6-甲基-4-取代氨基-5-嘧啶羧酸类化合物及其制备方法和用途
CN115232076A (zh) * 2022-07-25 2022-10-25 南通大学 苯氨基取代的嘧啶氨基酸衍生物及其制备方法与应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU206337B (en) * 1988-12-29 1992-10-28 Mitsui Petrochemical Ind Process for producing pyrimidine derivatives and pharmaceutical compositions
JP2744663B2 (ja) * 1988-12-29 1998-04-28 三井化学株式会社 ピリミジン類及びその薬学的に許容される塩類

Also Published As

Publication number Publication date
ATE119157T1 (de) 1995-03-15
AU653601B2 (en) 1994-10-06
DE9290039U1 (de) 1993-12-09
AU1776192A (en) 1992-11-17
NO933722D0 (no) 1993-10-15
EP0580753B1 (en) 1995-03-01
ES2068714T3 (es) 1995-04-16
IE921214A1 (en) 1992-10-21
EP0580753A1 (en) 1994-02-02
NZ242390A (en) 1994-09-27
BR9205906A (pt) 1994-07-05
DE69201559D1 (de) 1995-04-06
JPH06501023A (ja) 1994-01-27
CN1065863A (zh) 1992-11-04
MX9201763A (es) 1992-10-01
ZA922815B (en) 1993-10-18
FI934565A (fi) 1993-10-15
IE64915B1 (en) 1995-09-20
YU39992A (sh) 1995-01-31
GR3015921T3 (en) 1995-07-31
NO933722L (no) 1993-10-15
DK0580753T3 (da) 1995-07-03
DE69201559T2 (de) 1995-07-13
HU9302929D0 (en) 1993-12-28
HUT65177A (en) 1994-05-02
CZ390992A3 (en) 1994-03-16
PT100386A (pt) 1993-06-30
JPH0819121B2 (ja) 1996-02-28
WO1992018498A1 (en) 1992-10-29
CA2108561A1 (en) 1992-10-18

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Legal Events

Date Code Title Description
FD Application lapsed