DE69201559D1 - Pyrimidinderivate zur erhöhung der antitumoraktivität. - Google Patents
Pyrimidinderivate zur erhöhung der antitumoraktivität.Info
- Publication number
- DE69201559D1 DE69201559D1 DE69201559T DE69201559T DE69201559D1 DE 69201559 D1 DE69201559 D1 DE 69201559D1 DE 69201559 T DE69201559 T DE 69201559T DE 69201559 T DE69201559 T DE 69201559T DE 69201559 D1 DE69201559 D1 DE 69201559D1
- Authority
- DE
- Germany
- Prior art keywords
- oractivity
- antitum
- increasing
- pyrimidine derivatives
- derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/48—Two nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US68689991A | 1991-04-17 | 1991-04-17 | |
| PCT/US1992/002434 WO1992018498A1 (en) | 1991-04-17 | 1992-03-30 | Pyrimidine derivatives for enhancing antitumor activity |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69201559D1 true DE69201559D1 (de) | 1995-04-06 |
| DE69201559T2 DE69201559T2 (de) | 1995-07-13 |
Family
ID=24758194
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE9290039U Expired - Lifetime DE9290039U1 (de) | 1991-04-17 | 1992-03-30 | Pyrimidinderivate zur Verbesserung der Anti-Tumor-Aktivität |
| DE69201559T Expired - Fee Related DE69201559T2 (de) | 1991-04-17 | 1992-03-30 | Pyrimidinderivate zur erhöhung der antitumoraktivität. |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE9290039U Expired - Lifetime DE9290039U1 (de) | 1991-04-17 | 1992-03-30 | Pyrimidinderivate zur Verbesserung der Anti-Tumor-Aktivität |
Country Status (22)
| Country | Link |
|---|---|
| EP (1) | EP0580753B1 (de) |
| JP (1) | JPH0819121B2 (de) |
| CN (1) | CN1065863A (de) |
| AT (1) | ATE119157T1 (de) |
| AU (1) | AU653601B2 (de) |
| BR (1) | BR9205906A (de) |
| CA (1) | CA2108561A1 (de) |
| CZ (1) | CZ390992A3 (de) |
| DE (2) | DE9290039U1 (de) |
| DK (1) | DK0580753T3 (de) |
| ES (1) | ES2068714T3 (de) |
| FI (1) | FI934565A (de) |
| GR (1) | GR3015921T3 (de) |
| HU (1) | HUT65177A (de) |
| IE (1) | IE64915B1 (de) |
| MX (1) | MX9201763A (de) |
| NO (1) | NO933722D0 (de) |
| NZ (1) | NZ242390A (de) |
| PT (1) | PT100386A (de) |
| WO (1) | WO1992018498A1 (de) |
| YU (1) | YU39992A (de) |
| ZA (1) | ZA922815B (de) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IN188411B (de) | 1997-03-27 | 2002-09-21 | Yuhan Corp | |
| US6440965B1 (en) * | 1997-10-15 | 2002-08-27 | Krenitsky Pharmaceuticals, Inc. | Substituted pyrimidine derivatives, their preparation and their use in the treatment of neurodegenerative or neurological disorders of the central nervous system |
| KR100272471B1 (ko) | 1998-11-17 | 2000-11-15 | 김선진 | 신규의 피리미딘 유도체 및 그의 제조방법 |
| US6593322B1 (en) | 1999-03-17 | 2003-07-15 | Signal Pharmaceuticals, Inc. | Compounds and methods for modulation of estrogen receptors |
| AU766648B2 (en) | 1999-03-17 | 2003-10-23 | Axys Pharmaceuticals, Inc. | Compounds and methods for modulation of estrogen receptors |
| US6583148B1 (en) | 1999-04-08 | 2003-06-24 | Krenitsky Pharmaceuticals, Inc. | Neurotrophic substituted pyrimidines |
| US6630469B2 (en) * | 2000-05-09 | 2003-10-07 | Bristol-Myers Squibb Company | 5-HT7 receptor antagonists |
| US7205297B2 (en) | 2000-07-24 | 2007-04-17 | Krenitsky Pharmaceuticals, Inc. | Substituted 5-alkynyl pyrimidines having neurotrophic activity |
| JP2005232081A (ja) * | 2004-02-19 | 2005-09-02 | Bayer Cropscience Ag | ベンジルピリミジン誘導体の農園芸用殺菌剤としての利用 |
| JP2010111702A (ja) | 2009-02-16 | 2010-05-20 | Tetsuya Nishio | 複素環化合物、その製造法および用途 |
| CN103333119A (zh) * | 2013-05-28 | 2013-10-02 | 中国药科大学 | 1,2-二氢-6-甲基-4-取代氨基-5-嘧啶羧酸类化合物及其制备方法和用途 |
| CN115232076A (zh) * | 2022-07-25 | 2022-10-25 | 南通大学 | 苯氨基取代的嘧啶氨基酸衍生物及其制备方法与应用 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2744663B2 (ja) * | 1988-12-29 | 1998-04-28 | 三井化学株式会社 | ピリミジン類及びその薬学的に許容される塩類 |
| HU206337B (en) * | 1988-12-29 | 1992-10-28 | Mitsui Petrochemical Ind | Process for producing pyrimidine derivatives and pharmaceutical compositions |
-
1992
- 1992-03-30 WO PCT/US1992/002434 patent/WO1992018498A1/en not_active Application Discontinuation
- 1992-03-30 HU HU9302929A patent/HUT65177A/hu unknown
- 1992-03-30 JP JP4509983A patent/JPH0819121B2/ja not_active Expired - Lifetime
- 1992-03-30 AT AT92911036T patent/ATE119157T1/de not_active IP Right Cessation
- 1992-03-30 DE DE9290039U patent/DE9290039U1/de not_active Expired - Lifetime
- 1992-03-30 ES ES92911036T patent/ES2068714T3/es not_active Expired - Lifetime
- 1992-03-30 AU AU17761/92A patent/AU653601B2/en not_active Expired - Fee Related
- 1992-03-30 DE DE69201559T patent/DE69201559T2/de not_active Expired - Fee Related
- 1992-03-30 CZ CS923909A patent/CZ390992A3/cs unknown
- 1992-03-30 EP EP92911036A patent/EP0580753B1/de not_active Expired - Lifetime
- 1992-03-30 DK DK92911036.9T patent/DK0580753T3/da active
- 1992-03-30 CA CA002108561A patent/CA2108561A1/en not_active Abandoned
- 1992-03-30 BR BR9205906A patent/BR9205906A/pt not_active Application Discontinuation
- 1992-04-14 MX MX9201763A patent/MX9201763A/es unknown
- 1992-04-15 PT PT100386A patent/PT100386A/pt not_active Application Discontinuation
- 1992-04-16 YU YU39992A patent/YU39992A/sh unknown
- 1992-04-16 ZA ZA922815A patent/ZA922815B/xx unknown
- 1992-04-16 NZ NZ242390A patent/NZ242390A/en unknown
- 1992-04-16 CN CN92102687A patent/CN1065863A/zh active Pending
- 1992-04-16 IE IE921214A patent/IE64915B1/en not_active IP Right Cessation
-
1993
- 1993-10-15 NO NO1993933722A patent/NO933722D0/no unknown
- 1993-10-15 FI FI934565A patent/FI934565A/fi not_active Application Discontinuation
-
1995
- 1995-04-25 GR GR950401042T patent/GR3015921T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO1992018498A1 (en) | 1992-10-29 |
| NZ242390A (en) | 1994-09-27 |
| AU1776192A (en) | 1992-11-17 |
| CN1065863A (zh) | 1992-11-04 |
| FI934565A0 (fi) | 1993-10-15 |
| BR9205906A (pt) | 1994-07-05 |
| IE64915B1 (en) | 1995-09-20 |
| NO933722L (no) | 1993-10-15 |
| YU39992A (sh) | 1995-01-31 |
| HUT65177A (en) | 1994-05-02 |
| ES2068714T3 (es) | 1995-04-16 |
| FI934565A (fi) | 1993-10-15 |
| AU653601B2 (en) | 1994-10-06 |
| JPH0819121B2 (ja) | 1996-02-28 |
| CA2108561A1 (en) | 1992-10-18 |
| EP0580753B1 (de) | 1995-03-01 |
| ZA922815B (en) | 1993-10-18 |
| IE921214A1 (en) | 1992-10-21 |
| DE9290039U1 (de) | 1993-12-09 |
| EP0580753A1 (de) | 1994-02-02 |
| DE69201559T2 (de) | 1995-07-13 |
| MX9201763A (es) | 1992-10-01 |
| ATE119157T1 (de) | 1995-03-15 |
| PT100386A (pt) | 1993-06-30 |
| GR3015921T3 (en) | 1995-07-31 |
| NO933722D0 (no) | 1993-10-15 |
| HU9302929D0 (en) | 1993-12-28 |
| JPH06501023A (ja) | 1994-01-27 |
| DK0580753T3 (da) | 1995-07-03 |
| CZ390992A3 (en) | 1994-03-16 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DK0572437T3 (da) | 2,4-diaminoquinazolinderivater til forøgelse af antitumorvirkning | |
| YU47993B (sh) | Derivati 2,4-diaminohinazolina | |
| GR3036250T3 (en) | Pyrimidine or triazine derivatives and herbicidal composition containing the same. | |
| DE69201559D1 (de) | Pyrimidinderivate zur erhöhung der antitumoraktivität. | |
| DE69110093D1 (de) | Pyrimidinderivate. | |
| GR1001386B (el) | Ετεροκυκλικές ενώσεις. |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition | ||
| 8339 | Ceased/non-payment of the annual fee |