FI933346A7 - Aminoalkylpyrrolidinyltiokarbapenemderivat - Google Patents

Aminoalkylpyrrolidinyltiokarbapenemderivat Download PDF

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Publication number
FI933346A7
FI933346A7 FI933346A FI933346A FI933346A7 FI 933346 A7 FI933346 A7 FI 933346A7 FI 933346 A FI933346 A FI 933346A FI 933346 A FI933346 A FI 933346A FI 933346 A7 FI933346 A7 FI 933346A7
Authority
FI
Finland
Prior art keywords
aminoalkylpyrrolidineylthiocarbapenem
derivatives
aminoalkylpyrrolidineylthiocarbapenem derivatives
Prior art date
Application number
FI933346A
Other languages
English (en)
Finnish (fi)
Other versions
FI933346A0 (fi
Inventor
Susumu Nakagawa
Shinji Kato
Satoshi Murase
Osamu Okamoto
Ryuji Mitomo
Katsumi Yamamoto
Koji Yamada
Hiroshi Fukatsu
Original Assignee
Banyu Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Banyu Pharma Co Ltd filed Critical Banyu Pharma Co Ltd
Publication of FI933346A0 publication Critical patent/FI933346A0/fi
Publication of FI933346A7 publication Critical patent/FI933346A7/fi

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D477/00Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
    • C07D477/10Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D477/12Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
    • C07D477/16Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hetero atoms or carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 3
    • C07D477/20Sulfur atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/12Oxygen or sulfur atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyrrole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • External Artificial Organs (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Materials For Medical Uses (AREA)
  • Hydrogenated Pyridines (AREA)
FI933346A 1991-11-27 1993-07-26 Aminoalkylpyrrolidinyltiokarbapenemderivat FI933346A7 (fi)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP33588891 1991-11-27
JP21561392 1992-07-21
PCT/JP1992/001544 WO1993011128A1 (en) 1991-11-27 1992-11-26 Aminoalkylpyrrolidinylthiocarbapenem derivatives

Publications (2)

Publication Number Publication Date
FI933346A0 FI933346A0 (fi) 1993-07-26
FI933346A7 true FI933346A7 (fi) 1993-07-26

Family

ID=26520964

Family Applications (1)

Application Number Title Priority Date Filing Date
FI933346A FI933346A7 (fi) 1991-11-27 1993-07-26 Aminoalkylpyrrolidinyltiokarbapenemderivat

Country Status (18)

Country Link
US (1) US5550121A (https=)
EP (1) EP0545290B1 (https=)
KR (1) KR0175674B1 (https=)
CN (1) CN1032061C (https=)
AT (1) ATE195736T1 (https=)
AU (2) AU651505B2 (https=)
BG (1) BG97965A (https=)
CA (1) CA2083980C (https=)
CZ (1) CZ150193A3 (https=)
DE (1) DE69231375T2 (https=)
FI (1) FI933346A7 (https=)
HU (2) HUT64345A (https=)
IL (1) IL103807A0 (https=)
MX (1) MX9206838A (https=)
PL (1) PL300122A1 (https=)
TW (1) TW209220B (https=)
WO (1) WO1993011128A1 (https=)
YU (1) YU100792A (https=)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5317016A (en) * 1991-08-20 1994-05-31 Shionogi Seiyaku Kabushiki Kaisha Pyrrolidylthiocarbapenem derivative
JP3848693B2 (ja) * 1994-07-06 2006-11-22 エーザイ・アール・アンド・ディー・マネジメント株式会社 新規カルバペネム誘導体
US7041660B2 (en) 1999-07-06 2006-05-09 Sankyo Company, Limited Crystalline 1-methylcarbapenem derivatives
TWI250160B (en) 1999-07-06 2006-03-01 Sankyo Co Crystalline 1-methylcarbapenem compound
TW200815442A (en) * 2006-04-28 2008-04-01 Kaneka Corp Improved method for the crystallization of intermediates of carbapenem antibiotics

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1281720C (en) * 1984-11-08 1991-03-19 Makoto Sunagawa Carbapenem compounds and production thereof
FI81576C (fi) * 1984-12-25 1990-11-12 Sankyo Co Foerfarande foer framstaellning av derivat av 6-(1-hydroxietyl)-2-(1,2-disubstituerade-4-pyrrolidinyltio)-2- karbapenem-3-karboxylsyra, vilka aer anvaendbara som laekemedel.
EP0243686B1 (en) * 1986-03-27 1992-07-15 Sumitomo Pharmaceuticals Company, Limited Beta-lactam compounds, and their production
DE69013131T2 (de) * 1989-12-29 1995-05-24 Banyu Pharma Co Ltd 2-(2-Cyclopropylpyrrolidin-4-ylthio)carbapenemderivate.
JPH05255332A (ja) * 1991-11-27 1993-10-05 Banyu Pharmaceut Co Ltd アルキルアミノアルキルピロリジニルチオカルバペネム誘導体

Also Published As

Publication number Publication date
BG97965A (bg) 1994-05-27
AU2963292A (en) 1993-06-03
CZ150193A3 (en) 1994-03-16
CA2083980C (en) 2003-04-29
FI933346A0 (fi) 1993-07-26
PL300122A1 (en) 1994-04-18
CA2083980A1 (en) 1993-05-28
EP0545290B1 (en) 2000-08-23
HU210817A9 (en) 1995-08-28
WO1993011128A1 (en) 1993-06-10
CN1073176A (zh) 1993-06-16
AU651505B2 (en) 1994-07-21
MX9206838A (es) 1993-05-31
HUT64345A (en) 1993-12-28
DE69231375D1 (de) 2000-09-28
IL103807A0 (en) 1993-04-04
US5550121A (en) 1996-08-27
YU100792A (sh) 1995-10-24
TW209220B (https=) 1993-07-11
HU9302170D0 (en) 1993-10-28
AU667786B2 (en) 1996-04-04
EP0545290A1 (en) 1993-06-09
KR0175674B1 (ko) 1999-03-20
CN1032061C (zh) 1996-06-19
KR930703322A (ko) 1993-11-29
DE69231375T2 (de) 2001-03-01
ATE195736T1 (de) 2000-09-15
AU7589494A (en) 1995-01-27

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