FI931880L - Cykliska iminoderivat, foerfarande foer deras framstaellning och dessa foereningar innehaollande laekemedel - Google Patents
Cykliska iminoderivat, foerfarande foer deras framstaellning och dessa foereningar innehaollande laekemedel Download PDFInfo
- Publication number
- FI931880L FI931880L FI931880A FI931880A FI931880L FI 931880 L FI931880 L FI 931880L FI 931880 A FI931880 A FI 931880A FI 931880 A FI931880 A FI 931880A FI 931880 L FI931880 L FI 931880L
- Authority
- FI
- Finland
- Prior art keywords
- foerfarande foer
- cyclic derivatives
- deras framstaellning
- framstaellning och
- foer deras
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/24—Oxygen or sulfur atoms
- C07D207/26—2-Pyrrolidones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
- C07F9/572—Five-membered rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Pyrrole Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Plural Heterocyclic Compounds (AREA)
- Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
- Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE4213919A DE4213919A1 (de) | 1992-04-28 | 1992-04-28 | Cyclische iminoderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| FI931880A0 FI931880A0 (fi) | 1993-04-27 |
| FI931880A7 FI931880A7 (fi) | 1993-10-29 |
| FI931880L true FI931880L (fi) | 1993-10-29 |
Family
ID=6457638
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI931880A FI931880L (fi) | 1992-04-28 | 1993-04-27 | Cykliska iminoderivat, foerfarande foer deras framstaellning och dessa foereningar innehaollande laekemedel |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US5576444A (cs) |
| EP (1) | EP0567966B1 (cs) |
| JP (1) | JP3315463B2 (cs) |
| KR (1) | KR940005569A (cs) |
| AT (1) | ATE170509T1 (cs) |
| AU (1) | AU662223B2 (cs) |
| CA (1) | CA2095009A1 (cs) |
| DE (2) | DE4213919A1 (cs) |
| DK (1) | DK0567966T3 (cs) |
| ES (1) | ES2121888T3 (cs) |
| FI (1) | FI931880L (cs) |
| HU (1) | HUT70039A (cs) |
| IL (1) | IL105517A0 (cs) |
| MX (1) | MX9302448A (cs) |
| NO (1) | NO180045C (cs) |
| NZ (1) | NZ247512A (cs) |
| PL (1) | PL298717A1 (cs) |
| TW (1) | TW232006B (cs) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1993018058A1 (en) * | 1992-03-06 | 1993-09-16 | G.D. Searle & Co. | Peptides mimics useful as platelet aggregation inhibitors |
| DE4241632A1 (de) * | 1992-12-10 | 1994-06-16 | Thomae Gmbh Dr K | Carbonsäurederivate, diese Verbindungen enthaltende Arzneimittel und Verfahren zu ihrer Herstellung |
| ES2150489T3 (es) * | 1993-03-31 | 2000-12-01 | Searle & Co | 1-amidinofenil-pirrolidonas, -piperidinonas, -azetinonas como inhibidores de la agregacion de plaquetas. |
| EP0656348B1 (de) * | 1993-12-03 | 2000-05-03 | F. Hoffmann-La Roche Ag | Essigsäurederivate als Arzneimittel |
| EE9700141A (et) * | 1994-12-23 | 1997-12-15 | Dr. Karl Thomae Gmbh | Piperasiinderivaadid, neid sisaldavad ravimid, nende kasutamine ja valmistamise meetod |
| US5691364A (en) * | 1995-03-10 | 1997-11-25 | Berlex Laboratories, Inc. | Benzamidine derivatives and their use as anti-coagulants |
| DK0813525T3 (da) | 1995-03-10 | 2004-02-16 | Berlex Lab | Benzamidinderivater, deres fremstilling og anvendelse som antikoagulanter |
| US5612363A (en) * | 1995-06-02 | 1997-03-18 | Berlex Laboratories, Inc. | N,N-di(aryl) cyclic urea derivatives as anti-coagulants |
| US5849759A (en) * | 1995-12-08 | 1998-12-15 | Berlex Laboratories, Inc. | Naphthyl-substituted benzimidazole derivatives as anti-coagulants |
| US5994375A (en) * | 1996-02-12 | 1999-11-30 | Berlex Laboratories, Inc. | Benzamidine derivatives substituted by amino acid and hydroxy acid derivatives and their use as anti-coagulants |
| AU1990197A (en) * | 1996-03-12 | 1997-10-01 | Bristol-Myers Squibb Company | Carbamyl guanidine and amidine prodrugs |
| US5753635A (en) * | 1996-08-16 | 1998-05-19 | Berlex Laboratories, Inc. | Purine derivatives and their use as anti-coagulants |
| US5693641A (en) * | 1996-08-16 | 1997-12-02 | Berlex Laboratories Inc. | Bicyclic pyrimidine derivatives and their use as anti-coagulants |
| JP3565864B2 (ja) | 1996-09-12 | 2004-09-15 | シエーリング アクチエンゲゼルシヤフト | 環式アミノ酸または環式ヒドロキシ酸誘導体により置換されたベンズアミジン誘導体および抗擬固薬としてのこれらの使用 |
| US6008234A (en) * | 1996-09-12 | 1999-12-28 | Berlex Laboratories, Inc. | Benzamidine derivatives substituted by cyclic amino acid and cyclic hydroxy acid derivatives and their use as anti-coagulants |
| US6004985A (en) | 1996-10-09 | 1999-12-21 | Berlex Laboratories, Inc. | Thio acid derived monocylic N-heterocyclics as anticoagulants |
| US7109326B2 (en) * | 1997-04-15 | 2006-09-19 | Genentech, Inc. | Halo-alkoxycarbonyl prodrugs |
| US6686364B2 (en) | 1997-12-08 | 2004-02-03 | Berlex Laboratories, Inc. | Benzamidine derivatives and their use as anti-coagulants |
| US6140351A (en) * | 1997-12-19 | 2000-10-31 | Berlex Laboratories, Inc. | Ortho-anthranilamide derivatives as anti-coagulants |
| DE69821985T2 (de) | 1997-12-19 | 2005-05-04 | Schering Ag | Ortho-anthranilamide derivate als antikoagulantien |
| US6114532A (en) * | 1998-02-03 | 2000-09-05 | Boehringer Ingelheim Pharma Kg | Bicyclic heterocycles, the preparation thereof, and their use as pharmaceuticals |
| AU2720199A (en) * | 1998-02-03 | 1999-08-23 | Boehringer Ingelheim Pharma Kg | Five-membered, benzo-condensed heterocycles used as antithrombotic agents |
| DE19844787A1 (de) * | 1998-09-30 | 2000-04-13 | Boehringer Ingelheim Pharma | Disubstituierte Pyrrolidinone, diese Verbindung enthaltende Arzneimittel und deren Verwendung sowie ihre Herstellung |
| US6262088B1 (en) | 1998-11-19 | 2001-07-17 | Berlex Laboratories, Inc. | Polyhydroxylated monocyclic N-heterocyclic derivatives as anti-coagulants |
| US6127376A (en) * | 1998-12-04 | 2000-10-03 | Berlex Laboratories, Inc. | Aryl and heterocyclyl substituted pyrimidine derivatives as anti-coagulants |
| US6350761B1 (en) | 1999-07-30 | 2002-02-26 | Berlex Laboratories, Inc. | Benzenamine derivatives as anti-coagulants |
| US7186855B2 (en) | 2001-06-11 | 2007-03-06 | Xenoport, Inc. | Prodrugs of GABA analogs, compositions and uses thereof |
| US7232924B2 (en) | 2001-06-11 | 2007-06-19 | Xenoport, Inc. | Methods for synthesis of acyloxyalkyl derivatives of GABA analogs |
| US6818787B2 (en) | 2001-06-11 | 2004-11-16 | Xenoport, Inc. | Prodrugs of GABA analogs, compositions and uses thereof |
| US8048917B2 (en) | 2005-04-06 | 2011-11-01 | Xenoport, Inc. | Prodrugs of GABA analogs, compositions and uses thereof |
| JP5440976B2 (ja) * | 2009-01-14 | 2014-03-12 | ホクト株式会社 | 血小板凝集抑制剤 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2123288A (en) * | 1982-07-16 | 1984-02-01 | Wellcome Found | Anti-thrombotic agent |
| EP0194548A3 (de) * | 1985-03-12 | 1988-08-17 | Dr. Karl Thomae GmbH | Neue Sulfonylaminoäthylverbindungen, diese Verbindungen enthaltende Arzneimittel und Verfahren zu ihrer Herstellung |
| DK117986A (da) * | 1985-03-16 | 1986-09-17 | Wellcome Found | Arylderivater, fremgangsmaader til deres fremstilling og deres anvendelse |
| DE3823299A1 (de) * | 1988-07-07 | 1990-01-11 | Schering Ag | Substituierte phenyl-pyrrolidin-2-one, -oxazolidin-2-one und -imidazolidin-2-one, ihre herstellung sowie verwendung in arzneimitteln |
| JPH02247166A (ja) * | 1989-03-17 | 1990-10-02 | Taisho Pharmaceut Co Ltd | ３―ピロリン―２―オン誘導体 |
| DE3932403A1 (de) * | 1989-05-12 | 1991-04-11 | Thomae Gmbh Dr K | Neue arylsulfonamide, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung |
| US5026861A (en) * | 1989-07-17 | 1991-06-25 | Merrell Dow Pharmaceuticals | Substituted 1,5-dihydro-4-(N-methylhydroxylamino)-2H-pyrrol-2-ones |
| DE4035961A1 (de) * | 1990-11-02 | 1992-05-07 | Thomae Gmbh Dr K | Cyclische iminoderivate, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung |
| DE4107857A1 (de) * | 1991-03-12 | 1992-09-17 | Thomae Gmbh Dr K | Cyclische harnstoffderivate, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung |
| DE4124942A1 (de) * | 1991-07-27 | 1993-01-28 | Thomae Gmbh Dr K | 5-gliedrige heterocyclen, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
| DE4127404A1 (de) * | 1991-08-19 | 1993-02-25 | Thomae Gmbh Dr K | Cyclische iminoderivate, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung |
-
1992
- 1992-04-28 DE DE4213919A patent/DE4213919A1/de not_active Withdrawn
-
1993
- 1993-03-09 TW TW082101712A patent/TW232006B/zh active
- 1993-04-26 EP EP93106724A patent/EP0567966B1/de not_active Expired - Lifetime
- 1993-04-26 DE DE59308940T patent/DE59308940D1/de not_active Expired - Fee Related
- 1993-04-26 ES ES93106724T patent/ES2121888T3/es not_active Expired - Lifetime
- 1993-04-26 US US08/053,037 patent/US5576444A/en not_active Expired - Lifetime
- 1993-04-26 DK DK93106724T patent/DK0567966T3/da active
- 1993-04-26 AT AT93106724T patent/ATE170509T1/de not_active IP Right Cessation
- 1993-04-27 PL PL29871793A patent/PL298717A1/xx unknown
- 1993-04-27 NZ NZ247512A patent/NZ247512A/en unknown
- 1993-04-27 MX MX9302448A patent/MX9302448A/es unknown
- 1993-04-27 HU HU9301222A patent/HUT70039A/hu unknown
- 1993-04-27 KR KR1019930007059A patent/KR940005569A/ko not_active Withdrawn
- 1993-04-27 FI FI931880A patent/FI931880L/fi not_active Application Discontinuation
- 1993-04-27 IL IL105517A patent/IL105517A0/xx unknown
- 1993-04-27 JP JP09993093A patent/JP3315463B2/ja not_active Expired - Fee Related
- 1993-04-27 CA CA002095009A patent/CA2095009A1/en not_active Abandoned
- 1993-04-27 NO NO931526A patent/NO180045C/no unknown
- 1993-04-28 AU AU38222/93A patent/AU662223B2/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| NO931526D0 (no) | 1993-04-27 |
| NO931526L (no) | 1993-10-29 |
| FI931880A7 (fi) | 1993-10-29 |
| AU662223B2 (en) | 1995-08-24 |
| AU3822293A (en) | 1993-11-04 |
| ATE170509T1 (de) | 1998-09-15 |
| MX9302448A (es) | 1993-10-01 |
| HU9301222D0 (en) | 1993-07-28 |
| PL298717A1 (en) | 1994-01-24 |
| EP0567966B1 (de) | 1998-09-02 |
| US5576444A (en) | 1996-11-19 |
| ES2121888T3 (es) | 1998-12-16 |
| CA2095009A1 (en) | 1993-10-29 |
| DE59308940D1 (de) | 1998-10-08 |
| IL105517A0 (en) | 1993-08-18 |
| HUT70039A (en) | 1995-09-28 |
| JP3315463B2 (ja) | 2002-08-19 |
| JPH0673001A (ja) | 1994-03-15 |
| NZ247512A (en) | 1995-12-21 |
| DK0567966T3 (da) | 1999-05-31 |
| EP0567966A1 (de) | 1993-11-03 |
| TW232006B (cs) | 1994-10-11 |
| NO180045C (no) | 1997-02-05 |
| NO180045B (no) | 1996-10-28 |
| DE4213919A1 (de) | 1993-11-04 |
| FI931880A0 (fi) | 1993-04-27 |
| KR940005569A (ko) | 1994-03-21 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD | Application lapsed |