FI931079A - Mikrobmotverkande karbapenemderivat, deras framstaellning och terapeutiska anvaendning - Google Patents

Mikrobmotverkande karbapenemderivat, deras framstaellning och terapeutiska anvaendning Download PDF

Info

Publication number
FI931079A
FI931079A FI931079A FI931079A FI931079A FI 931079 A FI931079 A FI 931079A FI 931079 A FI931079 A FI 931079A FI 931079 A FI931079 A FI 931079A FI 931079 A FI931079 A FI 931079A
Authority
FI
Finland
Prior art keywords
hydrogen
microbother
machinery
useful
acylimidoyl
Prior art date
Application number
FI931079A
Other languages
English (en)
Other versions
FI103046B1 (fi
FI931079A0 (fi
FI103046B (fi
Inventor
Isao Kawamoto
Rokuro Endo
Masao Miyauchi
Katsuya Ishikawa
Katsuhiko Watanabe
Hiroshi Yasuda
Satoshi Ohya
Yukio Utsui
Original Assignee
Sankyo Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sankyo Co filed Critical Sankyo Co
Publication of FI931079A0 publication Critical patent/FI931079A0/fi
Publication of FI931079A publication Critical patent/FI931079A/fi
Application granted granted Critical
Publication of FI103046B1 publication Critical patent/FI103046B1/fi
Publication of FI103046B publication Critical patent/FI103046B/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
    • C07D477/10—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D477/12—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
    • C07D477/16—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hetero atoms or carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 3
    • C07D477/20—Sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Materials For Medical Uses (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
FI931079A 1992-03-11 1993-03-10 Menetelmä lääkeaineina käyttökelpoisten pyrrolidinyylitiokarbapeneemij ohdannaisten valmistamiseksi FI103046B (fi)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
JP5216392 1992-03-11
JP5216392 1992-03-11
JP24495392 1992-09-14
JP24495392 1992-09-14
JP24657892 1992-09-16
JP24657892 1992-09-16

Publications (4)

Publication Number Publication Date
FI931079A0 FI931079A0 (fi) 1993-03-10
FI931079A true FI931079A (fi) 1993-09-12
FI103046B1 FI103046B1 (fi) 1999-04-15
FI103046B FI103046B (fi) 1999-04-15

Family

ID=27294566

Family Applications (1)

Application Number Title Priority Date Filing Date
FI931079A FI103046B (fi) 1992-03-11 1993-03-10 Menetelmä lääkeaineina käyttökelpoisten pyrrolidinyylitiokarbapeneemij ohdannaisten valmistamiseksi

Country Status (19)

Country Link
EP (1) EP0560613B1 (fi)
KR (1) KR100258225B1 (fi)
CN (1) CN1037180C (fi)
AT (1) ATE173733T1 (fi)
AU (1) AU664422B2 (fi)
CA (1) CA2091486A1 (fi)
CZ (1) CZ290002B6 (fi)
DE (1) DE69322188T2 (fi)
DK (1) DK0560613T3 (fi)
ES (1) ES2125945T3 (fi)
FI (1) FI103046B (fi)
HK (1) HK1011976A1 (fi)
HU (1) HU218676B (fi)
IL (1) IL105020A (fi)
MX (1) MX9301361A (fi)
NO (1) NO303730B1 (fi)
NZ (1) NZ247129A (fi)
RU (1) RU2097383C1 (fi)
TW (1) TW249803B (fi)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU651887B2 (en) * 1991-06-04 1994-08-04 Sankyo Company Limited 1-methylcarbapenem derivatives, their preparation and their use as antibiotics
GB9515975D0 (en) 1995-08-04 1995-10-04 Zeneca Ltd Chemical compounds
DK0882728T3 (da) * 1995-12-21 2003-01-06 Sankyo Co 1-methylcarbapenemderivater
DK0900797T3 (da) * 1996-04-26 2002-09-09 Sankyo Co Et 1-methylcarbapenemderivat
AU4020897A (en) 1996-08-17 1998-03-06 Zeneca Limited 3-mercaptopyrrolidines as farnesyl protein transferase inhibitors
AU1415500A (en) * 1998-12-07 2000-06-26 Sankyo Company Limited 1-methylcarbapenem derivatives
US7041660B2 (en) 1999-07-06 2006-05-09 Sankyo Company, Limited Crystalline 1-methylcarbapenem derivatives
GB9930318D0 (en) 1999-12-22 2000-02-09 Zeneca Ltd Novel compounds
GB9930317D0 (en) 1999-12-22 2000-02-09 Zeneca Ltd Novel compounds
US7022841B2 (en) * 2001-09-26 2006-04-04 Merck & Co. Inc. Process for making carbapenem compounds
EP2308562B1 (en) * 2003-12-25 2015-02-25 Ono Pharmaceutical Co., Ltd. Azetidine ring compounds and drugs comprising the same
CN101367814B (zh) * 2007-06-28 2010-12-15 山东轩竹医药科技有限公司 被巯基吡咯烷甲酰哌啶取代的培南衍生物

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1283906C (en) * 1983-05-09 1991-05-07 Makoto Sunagawa .beta.-LACTAM COMPOUNDS AND PRODUCTION THEREOF
EP0243686B1 (en) * 1986-03-27 1992-07-15 Sumitomo Pharmaceuticals Company, Limited Beta-lactam compounds, and their production
CA2036163C (en) * 1990-02-14 2001-06-19 Makoto Sunagawa Novel beta-lactam compounds and their production
IE910606A1 (en) * 1990-02-23 1991-08-28 Sankyo Co Carbapenem derivatives having antibiotic activity, their¹preparation and their use
GB9107363D0 (en) * 1991-04-08 1991-05-22 Ici Plc Antibiotic compounds
AU651887B2 (en) * 1991-06-04 1994-08-04 Sankyo Company Limited 1-methylcarbapenem derivatives, their preparation and their use as antibiotics
CA2117899A1 (en) * 1992-04-13 1993-10-28 Masayoshi Murata Substituted 3-pyrrolidinylthio-carbapenems as antimicrobial agents

Also Published As

Publication number Publication date
IL105020A0 (en) 1993-07-08
CN1037180C (zh) 1998-01-28
CZ39393A3 (en) 1993-12-15
HU9300677D0 (en) 1993-05-28
RU2097383C1 (ru) 1997-11-27
FI103046B1 (fi) 1999-04-15
KR930019674A (ko) 1993-10-18
AU3515193A (en) 1993-09-16
NZ247129A (en) 1994-09-27
HUT64071A (en) 1993-11-29
TW249803B (fi) 1995-06-21
EP0560613A1 (en) 1993-09-15
HK1011976A1 (en) 1999-07-23
CN1079472A (zh) 1993-12-15
NO303730B1 (no) 1998-08-24
HU218676B (hu) 2000-10-28
EP0560613B1 (en) 1998-11-25
DK0560613T3 (da) 1999-08-09
FI931079A0 (fi) 1993-03-10
DE69322188T2 (de) 1999-07-29
CZ290002B6 (cs) 2002-05-15
CA2091486A1 (en) 1993-09-12
IL105020A (en) 1997-04-15
ES2125945T3 (es) 1999-03-16
FI103046B (fi) 1999-04-15
MX9301361A (es) 1994-01-31
NO930884L (no) 1993-09-13
DE69322188D1 (de) 1999-01-07
ATE173733T1 (de) 1998-12-15
KR100258225B1 (ko) 2000-08-01
AU664422B2 (en) 1995-11-16
NO930884D0 (no) 1993-03-11

Similar Documents

Publication Publication Date Title
DE69319976D1 (de) 7-Substituierte-9-substituierte Glycylamido-6-Demethyl-6-Deoxytetracycline
DE69331774D1 (de) 7-Substituierte-8-substituierte-9-substituierte Amino-7-Demethyl-6-Deoxy-Tetracycline als antibiotische Mittel
TW269678B (fi)
TW290546B (fi)
FI925595A (fi) Piperazinyl- och piperidinylcyklohexanolfoereningar
AU4523797A (en) Atherosclerosis treatment
FI931079A (fi) Mikrobmotverkande karbapenemderivat, deras framstaellning och terapeutiska anvaendning
DK0604183T3 (da) HIV-protease-inhibitorer anvendelige i behandlingen af AIDS
EA200000728A1 (ru) Замещенные 2-бензиламино-2-фенилацетамидные соединения
RU93004678A (ru) Противомикробные производные карбапенема, способы их получения и применение
ES8703456A1 (es) Procedimiento para preparar derivados de nitrofurano
JPS5681518A (en) Composition and treatment
FR2756565B1 (fr) Nouveaux derives d'histidine et leur utilisation en cosmetique ou en pharmacie
FI20021652A (fi) Tratsodonin alkyylijohdannaisten valmistuksessa käyttökelpoisia välituotteita
FI960588A0 (fi) Mikrobisideina käytettäviä tiokarbamoyyliyhdisteitä
AU6029090A (en) Improvements in or relating to organic compounds
TR199701286T1 (xx) Karbapenemlerin esterleri.
EE9400233A (et) 1,5,6,7-tetrahüdro-4H-indasool-4-ooni sisaldav ravim, uus 1,5,6,7-tetrahüdro-4H-indasool-4-oon ja meetodid nende saamiseks
DE59300004D1 (de) 2,3-Dihydroxychinoxalinverbindungen.
IT1262952B (it) Tetraalchilpiperidine, loro preparazione e loro impiego come stabilizzanti alla luce. (caso 153-5502)
TH13040EX (th) คาร์บาพีเนม ซึ่งมีหมู่เฟนิลที่ถูกแทนที่ด้วย หมู่คาร์บอกซิ, กรรมวิธีสำหรับเตรียมสารเหล่านั้น สารขั้นกลางการใช้เป็นสารปฏิชีวนะ

Legal Events

Date Code Title Description
FG Patent granted

Owner name: SANKYO COMPANY LIMITED