ES8703456A1 - Procedimiento para preparar derivados de nitrofurano - Google Patents

Procedimiento para preparar derivados de nitrofurano

Info

Publication number
ES8703456A1
ES8703456A1 ES553851A ES553851A ES8703456A1 ES 8703456 A1 ES8703456 A1 ES 8703456A1 ES 553851 A ES553851 A ES 553851A ES 553851 A ES553851 A ES 553851A ES 8703456 A1 ES8703456 A1 ES 8703456A1
Authority
ES
Spain
Prior art keywords
preparation
nitrofuran derivatives
therapeutical use
nitrofuran
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES553851A
Other languages
English (en)
Other versions
ES553851A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Synthelabo SA
Original Assignee
Synthelabo SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Synthelabo SA filed Critical Synthelabo SA
Publication of ES8703456A1 publication Critical patent/ES8703456A1/es
Publication of ES553851A0 publication Critical patent/ES553851A0/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

Abstract

PROCEDIMIENTO PARA OBTENER DERIVADOS DE NITROFURANO. COMPRENDE: A) HACER REACCIONAR ACIDO ETILENICO CON HIDRAZIDA EN PRESENCIA DE DICICLOEXILCARBODIIMIDA PARA OBTENER UNA HIDRAZIDA DE FORMULA (II); B) ALDOLIZAR AL NITRO-5-FURANO-CARBOXILDEHIDO-2 CON ACETALDEHIDO; C) PURIFICAR AL PRODUCTO DE B) EN COLUMNA DE SILICE PARA OBTENER (NITRO-5-FURANO-2)-3-PROPENO-2-AL; Y D) CONDENSAR A (II) CON (NITRO-5-FURANOL-2)-3-PROPENO-2-AL EN METANOL Y ENTRE 20JC Y SU TEMPERATURA DE REFLUJO, PARA OBTENER UN COMPUESTO DE FORMULA (I). SIENDO: R, ALCOXI DE C 1 A 4 O H Y M, 0 O 1. SE UTILIZA COMO INHIBIDOR IN VITRO CONTRA BACILOS COMO STAPHYLOCOCCUS AUREUS Y TRICLONOMAS.
ES553851A 1985-04-11 1986-04-10 Procedimiento para preparar derivados de nitrofurano Expired ES8703456A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8505424A FR2580281B1 (fr) 1985-04-11 1985-04-11 Derives du nitrofuranne, leur preparation et leur application en therapeutique

Publications (2)

Publication Number Publication Date
ES8703456A1 true ES8703456A1 (es) 1987-02-16
ES553851A0 ES553851A0 (es) 1987-02-16

Family

ID=9318115

Family Applications (1)

Application Number Title Priority Date Filing Date
ES553851A Expired ES8703456A1 (es) 1985-04-11 1986-04-10 Procedimiento para preparar derivados de nitrofurano

Country Status (18)

Country Link
US (1) US4711892A (es)
EP (1) EP0200605A1 (es)
JP (1) JPS61236776A (es)
KR (1) KR860008168A (es)
CN (1) CN86102565A (es)
AU (1) AU5591486A (es)
DK (1) DK161086A (es)
ES (1) ES8703456A1 (es)
FI (1) FI861526A (es)
FR (1) FR2580281B1 (es)
GR (1) GR860950B (es)
HU (1) HUT43592A (es)
IL (1) IL78357A0 (es)
MA (1) MA20660A1 (es)
NO (1) NO861240L (es)
PT (1) PT82364B (es)
TN (1) TNSN86054A1 (es)
ZA (1) ZA862708B (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE71839T1 (de) * 1986-04-07 1992-02-15 Upjohn Co Anthelmintische acylhydrazone verfahren zur verwendung und zusammensetzungen.
US4820718A (en) * 1987-09-17 1989-04-11 Sandoz Pharm. Corp. N-alkyl-(2- or 5-substituted-2-methoxycarbonyl aminoalkyl furanyl)-substituted cyclimmonium salts and use thereof in PAF inhibition
GB9615944D0 (en) * 1996-07-30 1996-09-11 Kodak Ltd A material,method and apparatus for inhibiting microbial growth in an aqueous medium
US7629002B2 (en) * 2000-02-16 2009-12-08 Chemeq Ltd. Antimicrobial polymeric compositions and method of treatment using them
WO2001070213A2 (en) * 2000-03-23 2001-09-27 Influx, Inc. Bactericidal antimicrobial methods and compositions for use in treating gram positive infections comprising an antibiotic potentiator having acyl hydrazide oxy amide or 8-hydroxy quinoline structure
US7767766B2 (en) * 2003-11-06 2010-08-03 Chemeq Ltd. Method of manufacture of polyacrolein
CN107311967B (zh) * 2017-04-25 2019-07-23 西华大学 N-[3-(2-呋喃基)]亚丙烯基-2-氰基-3-杂环基丙烯酰肼类衍生物及其应用
CN108558858A (zh) * 2018-05-23 2018-09-21 成都师范学院 硝基呋喃类抗结核化合物
CN110642743B (zh) * 2019-10-18 2021-01-01 中国农业大学 硝呋酚酰肼半抗原和人工抗原及其制备方法与应用
CN114225095A (zh) * 2021-12-10 2022-03-25 中国科学技术大学 生物基抗菌复合粘合材料及其制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2703322A (en) * 1951-03-17 1955-03-01 Hoffmann La Roche Derivatives of isonicotinyl hydrazine
US2874189A (en) * 1957-03-28 1959-02-17 Nat Drug Co Pharmaceuticals
US3072726A (en) * 1959-08-24 1963-01-08 Hoffmann La Roche N1-cycloalkanoyl and n1-[alpha-tri-alkyl]-alkanoyl-hydrazides and derivatives thereof

Also Published As

Publication number Publication date
CN86102565A (zh) 1986-11-12
MA20660A1 (fr) 1986-12-31
KR860008168A (ko) 1986-11-12
US4711892A (en) 1987-12-08
FR2580281B1 (fr) 1987-09-18
HUT43592A (en) 1987-11-30
TNSN86054A1 (fr) 1990-01-01
FI861526A (fi) 1986-10-12
PT82364B (fr) 1988-03-18
GR860950B (en) 1986-08-06
DK161086D0 (da) 1986-04-10
FR2580281A1 (fr) 1986-10-17
FI861526A0 (fi) 1986-04-10
ZA862708B (en) 1986-11-26
IL78357A0 (en) 1986-07-31
EP0200605A1 (fr) 1986-11-05
NO861240L (no) 1986-10-13
ES553851A0 (es) 1987-02-16
PT82364A (fr) 1986-05-01
DK161086A (da) 1986-10-12
JPS61236776A (ja) 1986-10-22
AU5591486A (en) 1986-10-16

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