FI922189A - Förfarande för framställning av propionsyraderivat - Google Patents

Förfarande för framställning av propionsyraderivat Download PDF

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Publication number
FI922189A
FI922189A FI922189A FI922189A FI922189A FI 922189 A FI922189 A FI 922189A FI 922189 A FI922189 A FI 922189A FI 922189 A FI922189 A FI 922189A FI 922189 A FI922189 A FI 922189A
Authority
FI
Finland
Prior art keywords
preparation
propionic acid
acid derivatives
separated
epoxypropionic acid
Prior art date
Application number
FI922189A
Other languages
English (en)
Finnish (fi)
Other versions
FI93833C (sv
FI922189A0 (sv
FI93833B (sv
Inventor
Olli Aaltonen
Martti Alkio
Anneli Hase
Martti Hytoenen
Pekka Kairisalo
Veikko Komppa
Original Assignee
Orion Yhtymae Oy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Orion Yhtymae Oy filed Critical Orion Yhtymae Oy
Publication of FI922189A0 publication Critical patent/FI922189A0/sv
Priority to FI922189A priority Critical patent/FI93833C/sv
Priority to IL105505A priority patent/IL105505A/xx
Priority to HU9301195A priority patent/HU212448B/hu
Priority to US08/058,125 priority patent/US5296618A/en
Priority to AT93107835T priority patent/ATE127796T1/de
Priority to DE69300471T priority patent/DE69300471T2/de
Priority to ES93107835T priority patent/ES2077454T3/es
Priority to EP93107835A priority patent/EP0569992B1/en
Priority to AU40708/93A priority patent/AU4070893A/en
Priority to DK93107835.6T priority patent/DK0569992T3/da
Priority to PCT/FI1993/000205 priority patent/WO1993023394A1/en
Priority to JP5113380A priority patent/JPH0632787A/ja
Priority to CA002096316A priority patent/CA2096316C/en
Publication of FI922189A publication Critical patent/FI922189A/sv
Application granted granted Critical
Publication of FI93833B publication Critical patent/FI93833B/sv
Publication of FI93833C publication Critical patent/FI93833C/sv
Priority to GR950402916T priority patent/GR3017822T3/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
    • C07D285/01—Five-membered rings
    • C07D285/02—Thiadiazoles; Hydrogenated thiadiazoles
    • C07D285/04—Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
    • C07D285/10—1,2,5-Thiadiazoles; Hydrogenated 1,2,5-thiadiazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B57/00—Separation of optically-active compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/48—Compounds containing oxirane rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Epoxy Compounds (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FI922189A 1992-05-14 1992-05-14 Förfarande för framställning av propionsyraderivat FI93833C (sv)

Priority Applications (14)

Application Number Priority Date Filing Date Title
FI922189A FI93833C (sv) 1992-05-14 1992-05-14 Förfarande för framställning av propionsyraderivat
IL105505A IL105505A (en) 1992-05-14 1993-04-23 Method for the separation of the derivatives of epoxy-propionic acid
HU9301195A HU212448B (en) 1992-05-14 1993-04-23 Process for producing propionic acid derivatives
US08/058,125 US5296618A (en) 1992-05-14 1993-05-10 Method for the manufacture of the derivatives of propionic acid
AU40708/93A AU4070893A (en) 1992-05-14 1993-05-13 Method for producing s-timolol
DE69300471T DE69300471T2 (de) 1992-05-14 1993-05-13 Verfahren zur Herstellung von Derivaten der epoxypropionsäure.
ES93107835T ES2077454T3 (es) 1992-05-14 1993-05-13 Metodo para la preparacion de derivados opticamente activos de acido epoxipropionico.
EP93107835A EP0569992B1 (en) 1992-05-14 1993-05-13 Method for the preparation of optically active derivatives of epoxypropionic acid
AT93107835T ATE127796T1 (de) 1992-05-14 1993-05-13 Verfahren zur herstellung von derivaten der epoxypropionsäure.
DK93107835.6T DK0569992T3 (da) 1992-05-14 1993-05-13 Fremgangsmåde til fremstilling af optisk aktive derivater af epoxypropionsyre
PCT/FI1993/000205 WO1993023394A1 (en) 1992-05-14 1993-05-13 Method for producing s-timolol
JP5113380A JPH0632787A (ja) 1992-05-14 1993-05-14 プロピオン酸誘導体の製造法
CA002096316A CA2096316C (en) 1992-05-14 1993-05-14 Method for the manufacture of the derivatives of propionic acid
GR950402916T GR3017822T3 (en) 1992-05-14 1995-10-19 Method for the preparation of optically active derivatives of epoxypropionic acid.

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FI922189 1992-05-14
FI922189A FI93833C (sv) 1992-05-14 1992-05-14 Förfarande för framställning av propionsyraderivat

Publications (4)

Publication Number Publication Date
FI922189A0 FI922189A0 (sv) 1992-05-14
FI922189A true FI922189A (sv) 1993-11-15
FI93833B FI93833B (sv) 1995-02-28
FI93833C FI93833C (sv) 1995-06-12

Family

ID=8535288

Family Applications (1)

Application Number Title Priority Date Filing Date
FI922189A FI93833C (sv) 1992-05-14 1992-05-14 Förfarande för framställning av propionsyraderivat

Country Status (14)

Country Link
US (1) US5296618A (sv)
EP (1) EP0569992B1 (sv)
JP (1) JPH0632787A (sv)
AT (1) ATE127796T1 (sv)
AU (1) AU4070893A (sv)
CA (1) CA2096316C (sv)
DE (1) DE69300471T2 (sv)
DK (1) DK0569992T3 (sv)
ES (1) ES2077454T3 (sv)
FI (1) FI93833C (sv)
GR (1) GR3017822T3 (sv)
HU (1) HU212448B (sv)
IL (1) IL105505A (sv)
WO (1) WO1993023394A1 (sv)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3426702B2 (ja) * 1993-09-17 2003-07-14 ダイセル化学工業株式会社 脂肪族エポキシド類の立体異性体の分割方法
US5514818A (en) * 1993-09-17 1996-05-07 Daicel Chemical Industries, Ltd. Resolution of stereoisomers of aliphatic epoxides
FI102758B1 (sv) * 1995-03-03 1999-02-15 Santen Oy Förfarande för att framställa en ren cyklosporinform
US6224775B1 (en) * 1997-09-08 2001-05-01 Villanova University Method of separating chemical mixtures
GB0214617D0 (en) * 2002-06-25 2002-08-07 Applied Photophysics Ltd Separation of chiral compounds
JPWO2005075974A1 (ja) * 2004-02-03 2007-10-11 ダイセル化学工業株式会社 超臨界流体クロマトグラフィーによって光学異性体を分離する方法
CA3056923A1 (en) 2017-03-23 2018-09-27 Graybug Vision, Inc. Drugs and compositions for the treatment of ocular disorders

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3655663A (en) * 1969-04-21 1972-04-11 Burton K Wasson 4-(3-secondary amino-2-hydroxy-proxy) 1 2 5-thiadiazoles
US4252728A (en) * 1978-04-17 1981-02-24 Firmenich Sa Norbornane and norbornene derivatives
JPS55120575A (en) * 1979-03-09 1980-09-17 Nippon Kayaku Co Ltd Cis-2,3-epoxy-4-lower alkoxyphenylbutanoic acid derivative and its production
AU542157B2 (en) * 1980-08-29 1985-02-07 Byk Gulden Lomberg Chemische Fabrik Gmbh Epoxycycloalkylalkanecarboxylic acids, processes for their preparation, their use and medicaments containing them
US4437939A (en) * 1981-07-17 1984-03-20 The Halcon Sd Group, Inc. Process for separating ethylene oxide from aqueous solutions
US4552695A (en) * 1983-04-21 1985-11-12 Shionogi & Co., Ltd. Process for production of diltiazem hydrochloride
JPS6013775A (ja) * 1983-07-05 1985-01-24 Sawai Seiyaku Kk 光学活性３−（ｐ−アルコキシフエニル）グリシツド酸アルカリ金属塩の製造法
JPS6013776A (ja) * 1983-07-05 1985-01-24 Sawai Seiyaku Kk 光学活性３−（ｐ−アルコキシフエニル）グリシツド酸誘導体の製造法
DE3330005A1 (de) * 1983-08-19 1985-02-28 Wolfgang Dr. Graz Lindner Weinsaeuremonoester von optisch aktiven alkanolaminen, verfahren zu ihrer herstellung und ihre verwendung
JPS61145159A (ja) * 1984-12-20 1986-07-02 Nippon Chemiphar Co Ltd 新規な光学活性プロピオン酸エステル誘導体およびその製造法
JPS61145160A (ja) * 1984-12-20 1986-07-02 Nippon Chemiphar Co Ltd 光学活性なプロピオン酸誘導体の製造法
US4925790A (en) * 1985-08-30 1990-05-15 The Regents Of The University Of California Method of producing products by enzyme-catalyzed reactions in supercritical fluids
JPH066539B2 (ja) * 1986-03-14 1994-01-26 三共株式会社 α−ハイドロキシカルボン酸誘導体の製法
EP0305496A4 (en) * 1987-03-17 1989-07-11 Insite Vision Inc TIMOLOL DERIVATIVES.
WO1989010350A1 (en) * 1988-04-21 1989-11-02 Ici Australia Operations Proprietary Limited Preparation of an epoxide
US4885375A (en) * 1988-05-18 1989-12-05 Marion Laboratories, Inc. Resolution of 3-(4-methoxyphenyl)glycidic acid with in situ conversion to alkyl esters
NL8801311A (nl) * 1988-05-20 1989-12-18 Stamicarbon Fenylglycidaatstereoisomeren, omzettingsprodukten daarvan met 2-nitrothiofenol en de bereiding van diltiazem.
IL91453A0 (en) * 1988-09-02 1990-04-29 Tanabe Seiyaku Co Preparation of optically active 3-phenyl-glycidic acid esters
JP2655893B2 (ja) * 1988-10-20 1997-09-24 ユニチカ株式会社 光学活性なβ−ハロ乳酸又はグリシジル酸の合成法
US6521445B1 (en) * 1988-10-26 2003-02-18 Sepracor, Inc. Process for preparing optically active glycidate esters
DE3906953A1 (de) * 1989-03-04 1990-09-20 Byk Gulden Lomberg Chem Fab Verfahren zur herstellung optisch reiner oxirancarbonsaeuren
FI90995C (sv) * 1991-05-16 1994-04-25 Valtion Teknillinen Förfarande för framställning av kirala ämnen som rena optiska isomerer

Also Published As

Publication number Publication date
DE69300471T2 (de) 1996-03-14
HUT64316A (en) 1993-12-28
FI93833C (sv) 1995-06-12
IL105505A (en) 1997-03-18
HU212448B (en) 1996-06-28
FI922189A0 (sv) 1992-05-14
EP0569992A2 (en) 1993-11-18
GR3017822T3 (en) 1996-01-31
HU9301195D0 (en) 1993-08-30
DK0569992T3 (da) 1995-11-13
FI93833B (sv) 1995-02-28
CA2096316A1 (en) 1993-11-15
IL105505A0 (en) 1993-08-18
JPH0632787A (ja) 1994-02-08
CA2096316C (en) 1998-07-28
ATE127796T1 (de) 1995-09-15
US5296618A (en) 1994-03-22
EP0569992B1 (en) 1995-09-13
ES2077454T3 (es) 1995-11-16
DE69300471D1 (de) 1995-10-19
AU4070893A (en) 1993-12-13
WO1993023394A1 (en) 1993-11-25
EP0569992A3 (sv) 1994-03-16

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Legal Events

Date Code Title Description
GB Transfer or assigment of application

Owner name: ORION-YHTYMAE OY FERMION

BB Publication of examined application