FI915653A - 5-amino-5,6,7,8-tetrahydroquinoliner och beslaektade foereningar, foerfarande foer deras framstaellning och deras anvaendning som laekemedel. - Google Patents

5-amino-5,6,7,8-tetrahydroquinoliner och beslaektade foereningar, foerfarande foer deras framstaellning och deras anvaendning som laekemedel. Download PDF

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Publication number
FI915653A
FI915653A FI915653A FI915653A FI915653A FI 915653 A FI915653 A FI 915653A FI 915653 A FI915653 A FI 915653A FI 915653 A FI915653 A FI 915653A FI 915653 A FI915653 A FI 915653A
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FI
Finland
Prior art keywords
och
arylalkyl
alkyl
formula
deras
Prior art date
Application number
FI915653A
Other languages
English (en)
Other versions
FI915653A0 (fi
Inventor
Richard Charles Effland
David M Fink
Original Assignee
Hoechst Roussel Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Roussel Pharma filed Critical Hoechst Roussel Pharma
Publication of FI915653A0 publication Critical patent/FI915653A0/fi
Publication of FI915653A publication Critical patent/FI915653A/fi

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20Oxygen atoms
    • C07D215/22Oxygen atoms attached in position 2 or 4
    • C07D215/227Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 2
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38Nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Veterinary Medicine (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Adhesives Or Adhesive Processes (AREA)
  • Management, Administration, Business Operations System, And Electronic Commerce (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Quinoline Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
FI915653A 1990-12-03 1991-11-29 5-amino-5,6,7,8-tetrahydroquinoliner och beslaektade foereningar, foerfarande foer deras framstaellning och deras anvaendning som laekemedel. FI915653A (fi)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/620,811 US5110815A (en) 1990-12-03 1990-12-03 5-amino-5,6,7,8-tetrahydroquinolines and related compounds and pharmaceutical use

Publications (2)

Publication Number Publication Date
FI915653A0 FI915653A0 (fi) 1991-11-29
FI915653A true FI915653A (fi) 1992-06-04

Family

ID=24487491

Family Applications (1)

Application Number Title Priority Date Filing Date
FI915653A FI915653A (fi) 1990-12-03 1991-11-29 5-amino-5,6,7,8-tetrahydroquinoliner och beslaektade foereningar, foerfarande foer deras framstaellning och deras anvaendning som laekemedel.

Country Status (17)

Country Link
US (2) US5110815A (fi)
EP (1) EP0489379B1 (fi)
JP (1) JP3090514B2 (fi)
KR (1) KR100235506B1 (fi)
AT (1) ATE168371T1 (fi)
AU (1) AU639875B2 (fi)
CA (1) CA2056793C (fi)
DE (1) DE69129790T2 (fi)
DK (1) DK0489379T3 (fi)
ES (1) ES2119752T3 (fi)
FI (1) FI915653A (fi)
IE (1) IE914183A1 (fi)
NO (1) NO914734L (fi)
NZ (1) NZ240803A (fi)
PT (1) PT99674B (fi)
TW (1) TW211003B (fi)
ZA (1) ZA919480B (fi)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL112566A (en) * 1994-02-10 2000-10-31 Wyeth John & Brother Ltd Substituted quinolinones and pharmaceutical compositions containing them
IL112567A (en) * 1994-02-10 2000-02-29 Wyeth John & Brother Ltd Substituted quinolines their preparation and pharmaceutical compositions containing them
IL112568A0 (en) * 1994-02-10 1995-05-26 Wyeth John & Brother Ltd Substituted quinolines, their preparation and pharmaceutical compositions containing them
KR0158065B1 (ko) * 1995-05-29 1998-12-01 스기야마 가즈히코 반도체 집적회로장치 및 그 제조방법
AU758802B2 (en) 1998-09-30 2003-03-27 Takeda Pharmaceutical Company Limited Drugs for improving vesical excretory strength
TWI301760B (en) * 2004-02-27 2008-10-11 Merz Pharma Gmbh & Co Kgaa Tetrahydroquinolinones and their use as antagonists of metabotropic glutamate receptors

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4789678A (en) * 1986-08-25 1988-12-06 Hoechst-Roussel Pharmaceuticals, Inc. Memory enhancing α-alkyl-4-amino-3-quinolinemethanols and 1-(4-aralkylamino-3-quinolinyl)alkanones and related compounds
US4942168A (en) * 1987-07-13 1990-07-17 Hoechst-Roussel Pharmaceuticals Inc. Hydroxyquinoline amines, and method of enhancing memory in mammals
EP0361489A3 (en) * 1988-09-30 1991-06-12 Chugai Seiyaku Kabushiki Kaisha Novel 3,4-diaminoquinoline and pyridine compounds
JPH0322011A (ja) * 1989-06-19 1991-01-30 Nec Corp キーボード入力データ処理方式

Also Published As

Publication number Publication date
PT99674A (pt) 1992-10-30
TW211003B (fi) 1993-08-11
KR920012036A (ko) 1992-07-25
NO914734L (no) 1992-06-04
IE914183A1 (en) 1992-06-03
DE69129790D1 (de) 1998-08-20
CA2056793A1 (en) 1992-06-04
US5110815A (en) 1992-05-05
PT99674B (pt) 1999-05-31
ZA919480B (en) 1992-08-26
JPH04290872A (ja) 1992-10-15
NO914734D0 (no) 1991-12-02
AU639875B2 (en) 1993-08-05
DK0489379T3 (da) 1999-04-19
US5310914A (en) 1994-05-10
EP0489379A1 (en) 1992-06-10
CA2056793C (en) 2003-03-11
JP3090514B2 (ja) 2000-09-25
ATE168371T1 (de) 1998-08-15
FI915653A0 (fi) 1991-11-29
ES2119752T3 (es) 1998-10-16
EP0489379B1 (en) 1998-07-15
NZ240803A (en) 1994-07-26
AU8835291A (en) 1992-06-04
KR100235506B1 (ko) 1999-12-15
DE69129790T2 (de) 1999-05-06

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