FI911510A - Hydroximetylindolizidiner och -kinolizidiner. - Google Patents

Hydroximetylindolizidiner och -kinolizidiner. Download PDF

Info

Publication number
FI911510A
FI911510A FI911510A FI911510A FI911510A FI 911510 A FI911510 A FI 911510A FI 911510 A FI911510 A FI 911510A FI 911510 A FI911510 A FI 911510A FI 911510 A FI911510 A FI 911510A
Authority
FI
Finland
Prior art keywords
kinolizidiner
hydroximethyldolizidiner
och
compounds
indolizidines
Prior art date
Application number
FI911510A
Other languages
English (en)
Other versions
FI911510A0 (fi
Inventor
Paul Saiho Liu
Mohinder Singh Kang
Roland Stephen Rogers
Barry Lee Rhinehart
Original Assignee
Merrell Dow Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma
Publication of FI911510A0 publication Critical patent/FI911510A0/fi
Publication of FI911510A publication Critical patent/FI911510A/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D455/00—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
    • C07D455/02—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing not further condensed quinolizine ring systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Virology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
FI911510A 1990-03-30 1991-03-27 Hydroximetylindolizidiner och -kinolizidiner. FI911510A (fi)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/502,602 US5028614A (en) 1990-03-30 1990-03-30 Hydroxymethyl-indolizidines and quinolizidines and their use as α-glucosidase I inhibitors

Publications (2)

Publication Number Publication Date
FI911510A0 FI911510A0 (fi) 1991-03-27
FI911510A true FI911510A (fi) 1991-10-01

Family

ID=23998556

Family Applications (1)

Application Number Title Priority Date Filing Date
FI911510A FI911510A (fi) 1990-03-30 1991-03-27 Hydroximetylindolizidiner och -kinolizidiner.

Country Status (18)

Country Link
US (1) US5028614A (fi)
EP (1) EP0449294B1 (fi)
JP (1) JP3019270B2 (fi)
KR (1) KR100195422B1 (fi)
CN (1) CN1055362A (fi)
AT (1) ATE140228T1 (fi)
AU (1) AU638318B2 (fi)
CA (1) CA2038984C (fi)
DE (1) DE69120705T2 (fi)
ES (1) ES2093040T3 (fi)
FI (1) FI911510A (fi)
HU (1) HU208974B (fi)
IE (1) IE911063A1 (fi)
IL (1) IL97698A0 (fi)
NO (1) NO911237L (fi)
NZ (1) NZ237567A (fi)
PT (1) PT97201A (fi)
ZA (1) ZA912236B (fi)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5152054A (en) * 1990-05-25 1992-10-06 Seiko Epson Corporation Method of making film carrier structure for integrated circuit tape automated bonding
US5273981A (en) * 1990-10-18 1993-12-28 Monsanto Company Intramolecular carbamate derivative of 2,3-Di-O-blocked-1,4-dideoxy-4-fluoro-nojirimycins
WO1993002711A1 (en) * 1991-08-09 1993-02-18 Nycomed Innovation Ab Use of persistent free-radicals in magnetic resonance imaging
EP0738498A1 (en) * 1995-04-18 1996-10-23 Machida Endoscope Co., Ltd Surgical adhesive sprayer
US7285667B2 (en) * 2005-04-26 2007-10-23 Wyeth Process for the synthesis of functionalized indolizidines

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0235878A3 (en) * 1986-01-16 1989-06-14 Beecham Group Plc Novel compounds
CA1315276C (en) * 1987-07-02 1993-03-30 Paul S. Liu Castanospermine esters and glycosides
US5004746A (en) * 1987-09-29 1991-04-02 Merrell Dow Pharmaceuticals Inc. Anti-retroviral castanospermine esters
DE3737523A1 (de) * 1987-11-05 1989-05-18 Bayer Ag Verwendung von substituierten hydroxypiperidinen als antivirale mittel

Also Published As

Publication number Publication date
PT97201A (pt) 1991-11-29
NZ237567A (en) 1994-12-22
EP0449294A1 (en) 1991-10-02
HUT57209A (en) 1991-11-28
CA2038984A1 (en) 1991-10-01
CA2038984C (en) 2002-12-24
NO911237L (no) 1991-10-01
NO911237D0 (no) 1991-03-26
IL97698A0 (en) 1992-06-21
FI911510A0 (fi) 1991-03-27
AU638318B2 (en) 1993-06-24
CN1055362A (zh) 1991-10-16
KR100195422B1 (ko) 1999-06-15
JPH04221382A (ja) 1992-08-11
EP0449294B1 (en) 1996-07-10
AU7381991A (en) 1991-10-03
DE69120705T2 (de) 1996-11-07
HU911039D0 (en) 1991-10-28
JP3019270B2 (ja) 2000-03-13
DE69120705D1 (de) 1996-08-14
ZA912236B (en) 1991-12-24
IE911063A1 (en) 1991-10-09
ES2093040T3 (es) 1996-12-16
KR910016750A (ko) 1991-11-05
ATE140228T1 (de) 1996-07-15
HU208974B (en) 1994-02-28
US5028614A (en) 1991-07-02

Similar Documents

Publication Publication Date Title
EP0528858A4 (en) Inhibitors of dipeptidyl-aminopeptidase type iv
DK0791571T3 (da) Benzoylderivater
DE19975006I2 (de) Pharmazeutische Zusammensetzungen zur Behandlung gastrointestinaler St¦rungen.
DK0604183T3 (da) HIV-protease-inhibitorer anvendelige i behandlingen af AIDS
DE69405919D1 (de) Zusammensetzungen zur Behandlung von Keratinfasern
EP0328634A4 (en) Pharmaceutical compositions for the treatment of psoriasis
ATE140228T1 (de) Hydroxymethyl-indolizidine und -chinolizidine
WO1996031208A3 (de) Verwendung von substituierten piperidin- oder pyrrolidinverbindungen zur behandlung von sigma-rezeptor modulierten krankheiten
DK0444482T3 (da) Oxetanoner
EP0420116A3 (en) Novel substituted alkyl piperidines and their use as inhibitors of cholesterol synthesis
PT87704A (pt) Process for preparing pharmaceutical compositions for transdermal delivery containing a 1,4-dihydropyride derivative
DE59305733D1 (de) Verfahren zur Herstellung von 1,3-Difluorbenzol
DE69408394D1 (de) 4-Piperidino-piperidin zur Behandlung von Tumoren
IL98919A0 (en) Substituted piperidines and their use as inhibitors of cholesterol synthesis
DE69113773D1 (de) Verwendung von 3-aryl-5-alkylthio-4H-1,2,4-triazolen zur Behandlung von Überreflexen infolge von Rückenmarkstrauma.
DE68926222D1 (de) Verwendung von 1,2,3,4-Tetrahydroacridinen zur Behandlung von AIDS, sowie Verbindungen
DE69221649D1 (de) Lacidipin zur Behandlung der Arteriosklerosis
RU93055684A (ru) Соединения, ингибирующие вич-протеазу, способ их получения, фармацевтическая композиция, промежуточный продукт
DK1260222T3 (da) Farmaceutiske præparater indeholdende hidtil ukendte iso-butenyl-substituerede taxaner
NO881798L (no) Fremgangsmaate for fremstilling av et antiastmapreparat.