ZA912236B - Hydroxymethyl-indolizidines and quinolizidines - Google Patents

Hydroxymethyl-indolizidines and quinolizidines

Info

Publication number
ZA912236B
ZA912236B ZA912236A ZA912236A ZA912236B ZA 912236 B ZA912236 B ZA 912236B ZA 912236 A ZA912236 A ZA 912236A ZA 912236 A ZA912236 A ZA 912236A ZA 912236 B ZA912236 B ZA 912236B
Authority
ZA
South Africa
Prior art keywords
indolizidines
quinolizidines
hydroxymethyl
compounds
heptitol
Prior art date
Application number
ZA912236A
Other languages
English (en)
Inventor
Paul Saiho Liu
Saiho Liu Paul
Mohinder Singh Kang
Singh Kang Mohinder
Roland Stephen Rogers
Stephen Rogers Roland
Barry Lee Rhinehart
Lee Rhinehart Barry
Original Assignee
Merrell Dow Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma
Publication of ZA912236B publication Critical patent/ZA912236B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D455/00—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
    • C07D455/02—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing not further condensed quinolizine ring systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Virology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Obesity (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
ZA912236A 1990-03-30 1991-03-25 Hydroxymethyl-indolizidines and quinolizidines ZA912236B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/502,602 US5028614A (en) 1990-03-30 1990-03-30 Hydroxymethyl-indolizidines and quinolizidines and their use as α-glucosidase I inhibitors

Publications (1)

Publication Number Publication Date
ZA912236B true ZA912236B (en) 1991-12-24

Family

ID=23998556

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA912236A ZA912236B (en) 1990-03-30 1991-03-25 Hydroxymethyl-indolizidines and quinolizidines

Country Status (18)

Country Link
US (1) US5028614A (fi)
EP (1) EP0449294B1 (fi)
JP (1) JP3019270B2 (fi)
KR (1) KR100195422B1 (fi)
CN (1) CN1055362A (fi)
AT (1) ATE140228T1 (fi)
AU (1) AU638318B2 (fi)
CA (1) CA2038984C (fi)
DE (1) DE69120705T2 (fi)
ES (1) ES2093040T3 (fi)
FI (1) FI911510A (fi)
HU (1) HU208974B (fi)
IE (1) IE911063A1 (fi)
IL (1) IL97698A0 (fi)
NO (1) NO911237L (fi)
NZ (1) NZ237567A (fi)
PT (1) PT97201A (fi)
ZA (1) ZA912236B (fi)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5152054A (en) * 1990-05-25 1992-10-06 Seiko Epson Corporation Method of making film carrier structure for integrated circuit tape automated bonding
US5273981A (en) * 1990-10-18 1993-12-28 Monsanto Company Intramolecular carbamate derivative of 2,3-Di-O-blocked-1,4-dideoxy-4-fluoro-nojirimycins
CA2115260A1 (en) * 1991-08-09 1993-02-18 Klaes Golman Use of persistent free-radicals in magnetic resonance imaging
EP0738498A1 (en) * 1995-04-18 1996-10-23 Machida Endoscope Co., Ltd Surgical adhesive sprayer
US7285667B2 (en) * 2005-04-26 2007-10-23 Wyeth Process for the synthesis of functionalized indolizidines

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0235878A3 (en) * 1986-01-16 1989-06-14 Beecham Group Plc Novel compounds
CA1315276C (en) * 1987-07-02 1993-03-30 Paul S. Liu Castanospermine esters and glycosides
US5004746A (en) * 1987-09-29 1991-04-02 Merrell Dow Pharmaceuticals Inc. Anti-retroviral castanospermine esters
DE3737523A1 (de) * 1987-11-05 1989-05-18 Bayer Ag Verwendung von substituierten hydroxypiperidinen als antivirale mittel

Also Published As

Publication number Publication date
HUT57209A (en) 1991-11-28
EP0449294B1 (en) 1996-07-10
DE69120705D1 (de) 1996-08-14
KR100195422B1 (ko) 1999-06-15
ATE140228T1 (de) 1996-07-15
AU7381991A (en) 1991-10-03
CN1055362A (zh) 1991-10-16
IL97698A0 (en) 1992-06-21
NZ237567A (en) 1994-12-22
DE69120705T2 (de) 1996-11-07
JP3019270B2 (ja) 2000-03-13
EP0449294A1 (en) 1991-10-02
IE911063A1 (en) 1991-10-09
HU208974B (en) 1994-02-28
NO911237D0 (no) 1991-03-26
KR910016750A (ko) 1991-11-05
US5028614A (en) 1991-07-02
CA2038984A1 (en) 1991-10-01
FI911510A (fi) 1991-10-01
PT97201A (pt) 1991-11-29
HU911039D0 (en) 1991-10-28
CA2038984C (en) 2002-12-24
JPH04221382A (ja) 1992-08-11
ES2093040T3 (es) 1996-12-16
FI911510A0 (fi) 1991-03-27
NO911237L (no) 1991-10-01
AU638318B2 (en) 1993-06-24

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