DE69113773D1 - Verwendung von 3-aryl-5-alkylthio-4H-1,2,4-triazolen zur Behandlung von Überreflexen infolge von Rückenmarkstrauma. - Google Patents

Verwendung von 3-aryl-5-alkylthio-4H-1,2,4-triazolen zur Behandlung von Überreflexen infolge von Rückenmarkstrauma.

Info

Publication number
DE69113773D1
DE69113773D1 DE69113773T DE69113773T DE69113773D1 DE 69113773 D1 DE69113773 D1 DE 69113773D1 DE 69113773 T DE69113773 T DE 69113773T DE 69113773 T DE69113773 T DE 69113773T DE 69113773 D1 DE69113773 D1 DE 69113773D1
Authority
DE
Germany
Prior art keywords
triazoles
alkylthio
aryl
treatment
over
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69113773T
Other languages
English (en)
Other versions
DE69113773T2 (de
Inventor
John H Kehne
Francis P Miller
John M Kane
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aventis Pharmaceuticals Inc
Original Assignee
Merrell Dow Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US07/769,201 external-priority patent/US5158968A/en
Application filed by Merrell Dow Pharmaceuticals Inc filed Critical Merrell Dow Pharmaceuticals Inc
Application granted granted Critical
Publication of DE69113773D1 publication Critical patent/DE69113773D1/de
Publication of DE69113773T2 publication Critical patent/DE69113773T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4151,2-Diazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02Muscle relaxants, e.g. for tetanus or cramps

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pain & Pain Management (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Photoreceptors In Electrophotography (AREA)
DE69113773T 1990-12-20 1991-12-19 Verwendung von 3-aryl-5-alkylthio-4H-1,2,4-triazolen zur Behandlung von Überreflexen infolge von Rückenmarkstrauma. Expired - Fee Related DE69113773T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US63066690A 1990-12-20 1990-12-20
US07/769,201 US5158968A (en) 1987-01-27 1991-10-04 3-aryl-5-alkylthio-4H-1,2,4-traizoles for treatment of hyperreflexia due to spinal trauma

Publications (2)

Publication Number Publication Date
DE69113773D1 true DE69113773D1 (de) 1995-11-16
DE69113773T2 DE69113773T2 (de) 1996-04-25

Family

ID=27091200

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69113773T Expired - Fee Related DE69113773T2 (de) 1990-12-20 1991-12-19 Verwendung von 3-aryl-5-alkylthio-4H-1,2,4-triazolen zur Behandlung von Überreflexen infolge von Rückenmarkstrauma.

Country Status (8)

Country Link
EP (1) EP0495226B1 (de)
JP (1) JP3048191B2 (de)
KR (1) KR100192647B1 (de)
AT (1) ATE128867T1 (de)
AU (1) AU644500B2 (de)
DE (1) DE69113773T2 (de)
DK (1) DK0495226T3 (de)
IE (1) IE68424B1 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994027513A1 (en) * 1993-05-28 1994-12-08 Origin Medsystems, Inc. Retracting tip trocar with plunger sensor
DE4339412A1 (de) * 1993-11-18 1995-05-24 Bayer Ag Verfahren und neue Zwischenprodukte zur Herstellung von Triazolinonen
JPH09315972A (ja) * 1996-03-22 1997-12-09 Chugai Pharmaceut Co Ltd 脊髄損傷治療剤
AR022229A1 (es) * 1999-01-12 2002-09-04 Abbott Gmbh & Co Kg Compuestos de triazol, composicion farmaceutica que los comprende y uso de los mismos para preparar dicha composicion

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2593084B2 (ja) * 1986-12-19 1997-03-19 メレルダウファーマスーティカルズ インコーポレーテッド 5−アリールー3h−1,2,4−トリアゾールー3−オン類の神経変性障害の処置への用途
US4900743A (en) * 1987-01-27 1990-02-13 Merrell Dow Pharmaceuticals Inc. 3-aryl-5-alkylthio-4H-1,2,4-triazoles

Also Published As

Publication number Publication date
ATE128867T1 (de) 1995-10-15
EP0495226A2 (de) 1992-07-22
EP0495226B1 (de) 1995-10-11
DE69113773T2 (de) 1996-04-25
IE68424B1 (en) 1996-06-12
JP3048191B2 (ja) 2000-06-05
EP0495226A3 (en) 1992-09-16
AU8969291A (en) 1992-06-25
KR920011490A (ko) 1992-07-24
AU644500B2 (en) 1993-12-09
DK0495226T3 (da) 1995-11-27
KR100192647B1 (ko) 1999-06-15
IE914460A1 (en) 1992-07-01
JPH04334373A (ja) 1992-11-20

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee