FI901903A7 - Viruksenvastaisia aineita - Google Patents

Viruksenvastaisia aineita Download PDF

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Publication number
FI901903A7
FI901903A7 FI901903A FI901903A FI901903A7 FI 901903 A7 FI901903 A7 FI 901903A7 FI 901903 A FI901903 A FI 901903A FI 901903 A FI901903 A FI 901903A FI 901903 A7 FI901903 A7 FI 901903A7
Authority
FI
Finland
Prior art keywords
antiviral agents
antiviral
agents
Prior art date
Application number
FI901903A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI901903A0 (fi
Inventor
David Frederick Horrobin
John Charles Marshall Stewart
Michael David Winther
Original Assignee
Efamol Holdings
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB898908646A external-priority patent/GB8908646D0/en
Priority claimed from GB898921266A external-priority patent/GB8921266D0/en
Application filed by Efamol Holdings filed Critical Efamol Holdings
Publication of FI901903A0 publication Critical patent/FI901903A0/fi
Publication of FI901903A7 publication Critical patent/FI901903A7/fi

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
FI901903A 1989-04-17 1990-04-12 Viruksenvastaisia aineita FI901903A7 (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB898908646A GB8908646D0 (en) 1989-04-17 1989-04-17 Anti-viral agents
GB898921266A GB8921266D0 (en) 1989-09-20 1989-09-20 Anti-viral agents

Publications (2)

Publication Number Publication Date
FI901903A0 FI901903A0 (fi) 1990-04-12
FI901903A7 true FI901903A7 (fi) 1990-10-18

Family

ID=26295232

Family Applications (1)

Application Number Title Priority Date Filing Date
FI901903A FI901903A7 (fi) 1989-04-17 1990-04-12 Viruksenvastaisia aineita

Country Status (15)

Country Link
US (2) US5216142A (https=)
EP (2) EP0693498A1 (https=)
JP (1) JP2952505B2 (https=)
KR (1) KR100188616B1 (https=)
AT (1) ATE155142T1 (https=)
AU (1) AU637362B2 (https=)
CA (1) CA2014662C (https=)
DE (1) DE69031007T2 (https=)
DK (1) DK0393920T3 (https=)
ES (1) ES2108686T3 (https=)
FI (1) FI901903A7 (https=)
GR (1) GR3024835T3 (https=)
IE (1) IE980216A1 (https=)
NZ (1) NZ233297A (https=)
TW (1) TW215417B (https=)

Families Citing this family (41)

* Cited by examiner, † Cited by third party
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US6107499A (en) * 1988-02-26 2000-08-22 Neuromedica, Inc. Dopamine analog amide
IE980216A1 (en) * 1989-04-17 2000-02-23 Scotia Holdings Plc Anti-virals
AU651569B2 (en) * 1990-01-11 1994-07-28 Isis Pharmaceuticals, Inc. Compositions and methods for detecting and modulating RNA activity and gene expression
US5459255A (en) * 1990-01-11 1995-10-17 Isis Pharmaceuticals, Inc. N-2 substituted purines
US6262241B1 (en) * 1990-08-13 2001-07-17 Isis Pharmaceuticals, Inc. Compound for detecting and modulating RNA activity and gene expression
GB2260319B (en) * 1991-10-07 1995-12-06 Norsk Hydro As Acyl derivatives of nucleosides and nucleoside analogues having anti-viral activity
GB9307043D0 (en) * 1993-04-05 1993-05-26 Norsk Hydro As Chemical compounds
US6015821A (en) * 1995-05-01 2000-01-18 Horrobin; David Frederick Nicotinic acid esters and pharmaceutical compositions containing them
MY118354A (en) * 1995-05-01 2004-10-30 Scarista Ltd 1,3-propane diol derivatives as bioactive compounds
USRE40546E1 (en) * 1996-05-01 2008-10-21 Scarista, Ltd. 1,3-Propane diol esters and ethers and methods for their use in drug delivery
US5639460A (en) * 1995-06-07 1997-06-17 Raymond; Hal C. Aqueous plant extract having antiviral activity
US5840711A (en) * 1995-06-21 1998-11-24 University Of Kentucky Research Foundation Compositions containing lithium inorganic salts and anti-viral drugs and method of treating viral infections such as acquired immunodeficiency syndrome
US6703394B2 (en) * 1996-02-16 2004-03-09 Medivir Ab Acyclic nucleoside derivatives
US5869493A (en) * 1996-02-16 1999-02-09 Medivir Ab Acyclic nucleoside derivatives
US6673784B1 (en) * 1996-03-19 2004-01-06 G. D. Searle & Co. Electrophilic ketones for the treatment of herpesvirus infections
WO1997035843A1 (en) * 1996-03-28 1997-10-02 Shionogi & Co., Ltd. Lymph-absorbable imidazole derivatives
US6576636B2 (en) 1996-05-22 2003-06-10 Protarga, Inc. Method of treating a liver disorder with fatty acid-antiviral agent conjugates
US5795909A (en) 1996-05-22 1998-08-18 Neuromedica, Inc. DHA-pharmaceutical agent conjugates of taxanes
US5952392A (en) * 1996-09-17 1999-09-14 Avanir Pharmaceuticals Long-chain alcohols, alkanes, fatty acids and amides in the treatment of burns and viral inhibition
US6440980B1 (en) * 1996-09-17 2002-08-27 Avanir Pharmaceuticals Synergistic inhibition of viral replication by long-chain hydrocarbons and nucleoside analogs
WO1999026958A1 (en) * 1997-11-25 1999-06-03 Protarga, Inc. Nucleoside analog compositions and uses thereof
US6153653A (en) * 1997-11-26 2000-11-28 Protarga, Inc. Choline compositions and uses thereof
US5955459A (en) * 1997-11-26 1999-09-21 Neuromedica, Inc. Fatty acid-antipsychotic compositions and uses thereof
US6197764B1 (en) 1997-11-26 2001-03-06 Protarga, Inc. Clozapine compositions and uses thereof
US5977174A (en) * 1997-11-26 1999-11-02 Neuromedica, Inc. Cholinergic compositions and uses thereof
US6225444B1 (en) 1998-02-10 2001-05-01 Protarga, Inc. Neuroprotective peptides and uses thereof
WO2000016625A1 (en) * 1998-09-23 2000-03-30 University Of Kentucky Research Foundation Antiviral drug compositions containing lithium inorganic salts
US7235583B1 (en) 1999-03-09 2007-06-26 Luitpold Pharmaceuticals, Inc., Fatty acid-anticancer conjugates and uses thereof
US6653318B1 (en) 1999-07-21 2003-11-25 Yale University 5-(E)-Bromovinyl uracil analogues and related pyrimidine nucleosides as anti-viral agents and methods of use
ATE556706T1 (de) * 2001-03-23 2012-05-15 Luitpold Pharm Inc Fettalkohol-arzneimittel-konjugate
AU2002303164A1 (en) * 2001-03-23 2002-10-08 Protarga, Inc. Fatty amine drug conjugates
US20060122174A1 (en) * 2001-09-21 2006-06-08 Henderson Morley Research & Development Limited Antiviral treatment
PL371945A1 (en) * 2001-10-16 2005-07-11 Avanir Pharmacueticals Viral inhibition by n-docosanol
TWI332507B (en) * 2002-11-19 2010-11-01 Hoffmann La Roche Antiviral nucleoside derivatives
WO2004052905A2 (en) * 2002-12-10 2004-06-24 F. Hoffmann-La Roche Ag Antiviral nucleoside derivatives
WO2005072113A2 (en) * 2004-01-20 2005-08-11 Harty Richard F Compositions and methods of treatment for inflammatory diseases
NO324263B1 (no) 2005-12-08 2007-09-17 Clavis Pharma Asa Kjemiske forbindelser, anvendelse derav ved behandling av kreft, samt farmasoytiske preparater som omfatter slike forbindelser
US20090111774A1 (en) * 2007-06-01 2009-04-30 Luitpold Pharmaceuticals, Inc. Pmea lipid conjugates
MX2010000424A (es) 2007-07-09 2010-08-10 Easter Virginia Medical School Derivados de nucleosidos sustituidos con propiedades antivirales y antimicrobianas.
UA99308C2 (ru) 2007-09-26 2012-08-10 Маунт Синай Скул Оф Медсин Аналог азацитидина и его применение
WO2015116782A1 (en) * 2014-01-29 2015-08-06 Board Of Regents, The University Of Texas System Nucleobase analogue derivatives and their applications

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2354288C2 (de) * 1973-10-30 1976-01-02 Hoechst Ag, 6000 Frankfurt Verfahren zur Herstellung von Aminophenylalkyläthern
JPS5132573A (en) * 1974-09-11 1976-03-19 Asahi Chemical Ind Nn ashiruarabinonukureoshido no seizohoho
US4340728A (en) * 1979-11-28 1982-07-20 Fuji Kagaku Kogyo Kabushiki Kaisha Nucleoside derivatives and process for preparing same
DE3100478A1 (de) * 1981-01-09 1982-08-12 Dr. Thilo & Co GmbH, 8021 Sauerlach 5'ester von pyrimidinnucleosiden mit antiviraler wirksamkeit, verfahren zur herstellung und daraus hergestellte arzneimittel
JPS5813394A (ja) * 1981-07-17 1983-01-25 Ajinomoto Co Inc １−β−Ｄ−リボフラノシル−４，５−置換イミダゾ−ルの製造法
EP0082668A1 (en) * 1981-12-18 1983-06-29 Beecham Group Plc 5-(2-Halogenovinyl)-2'-deoxyuridine derivatives, processes for their preparation, pharmaceutical compositions containing them and their use in treating viral infections
US5250535A (en) * 1982-02-01 1993-10-05 Syntex Inc. Substituted 9-(1 or 3-monoacyloxy or 1,3-diacyloxy-2-propoxymethyl) purines as antiviral agent
US4612314A (en) * 1982-12-22 1986-09-16 Syntex (U.S.A.) Inc. Substituted 9-(1 or 3-monoacyloxy or 1,3-diacyloxy-2-propoxymethyl) purines as antiviral agent
US4880820A (en) * 1983-06-24 1989-11-14 Merck & Co., Inc. Guanine derivatives
PT78769A (en) * 1983-06-24 1984-07-01 Merck & Co Inc Process for preparing (s)-9-(2,3-dihydroxy-1-propoxymethyl)guanine and derivatives thereof useful as antiviral agents
JPS6144897A (ja) * 1984-08-10 1986-03-04 Terumo Corp ５−フルオロウラシル誘導体およびこれを含有する医薬製剤
US5223263A (en) * 1988-07-07 1993-06-29 Vical, Inc. Liponucleotide-containing liposomes
CA1285935C (en) * 1985-03-16 1991-07-09 Janet Lister Rideout Therapeutic nucleosides
FR2580283B1 (fr) * 1985-04-15 1989-11-24 Toyo Jozo Kk Nouveau conjugue nucleoside-phospholipide
EP0217580A3 (en) * 1985-09-17 1990-11-07 The Wellcome Foundation Limited Therapeutic nucleosides
DE3778626D1 (de) * 1986-09-27 1992-06-04 Toyo Jozo Kk Nukleosid-phospholipid-konjugat.
DE3856557T2 (de) * 1987-10-28 2004-06-03 Wellstat Therapeutics Corp. Acyldeoxyribonukleosid-Derivate und Verwendungen davon
JP2894610B2 (ja) * 1987-10-28 1999-05-24 プロ−ニューロン，インコーポレーテッド アシル化ウリジンおよびシチジンならびにその使用
IE980216A1 (en) * 1989-04-17 2000-02-23 Scotia Holdings Plc Anti-virals

Also Published As

Publication number Publication date
IE980216A1 (en) 2000-02-23
HK1001003A1 (en) 1998-05-15
EP0693498A1 (en) 1996-01-24
EP0393920A2 (en) 1990-10-24
TW215417B (https=) 1993-11-01
NZ233297A (en) 1997-07-27
JP2952505B2 (ja) 1999-09-27
CA2014662C (en) 2002-09-17
AU637362B2 (en) 1993-05-27
CA2014662A1 (en) 1990-10-17
AU5329090A (en) 1990-10-18
US5276020A (en) 1994-01-04
US5216142A (en) 1993-06-01
FI901903A0 (fi) 1990-04-12
KR900015742A (ko) 1990-11-10
JPH02304084A (ja) 1990-12-17
GR3024835T3 (en) 1998-01-30
ES2108686T3 (es) 1998-01-01
DE69031007D1 (de) 1997-08-14
DK0393920T3 (da) 1997-09-22
ATE155142T1 (de) 1997-07-15
KR100188616B1 (ko) 1999-06-01
EP0393920A3 (en) 1991-07-03
EP0393920B1 (en) 1997-07-09
DE69031007T2 (de) 1997-12-04

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Legal Events

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FD Application lapsed

Owner name: EFAMOL HOLDINGS PLC