FI896014A0 - Heterocykliska derivat. - Google Patents
Heterocykliska derivat.Info
- Publication number
- FI896014A0 FI896014A0 FI896014A FI896014A FI896014A0 FI 896014 A0 FI896014 A0 FI 896014A0 FI 896014 A FI896014 A FI 896014A FI 896014 A FI896014 A FI 896014A FI 896014 A0 FI896014 A0 FI 896014A0
- Authority
- FI
- Finland
- Prior art keywords
- heterocyclis
- derivatives
- heterocyclis derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D309/10—Oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/04—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D307/18—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/20—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D313/00—Heterocyclic compounds containing rings of more than six members having one oxygen atom as the only ring hetero atom
- C07D313/02—Seven-membered rings
- C07D313/04—Seven-membered rings not condensed with other rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D335/00—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom
- C07D335/02—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pain & Pain Management (AREA)
- Immunology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Pulmonology (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Furan Compounds (AREA)
- Pyrane Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP88403313 | 1988-12-23 | ||
EP89401491 | 1989-05-31 |
Publications (1)
Publication Number | Publication Date |
---|---|
FI896014A0 true FI896014A0 (fi) | 1989-12-15 |
Family
ID=26118235
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FI896014A FI896014A0 (fi) | 1988-12-23 | 1989-12-15 | Heterocykliska derivat. |
Country Status (16)
Country | Link |
---|---|
US (1) | US5098930A (fr) |
EP (1) | EP0375404B1 (fr) |
JP (1) | JPH03135975A (fr) |
AU (1) | AU624663B2 (fr) |
CA (1) | CA2006377A1 (fr) |
DE (1) | DE68913022T2 (fr) |
DK (1) | DK654589A (fr) |
ES (1) | ES2062051T3 (fr) |
FI (1) | FI896014A0 (fr) |
GB (1) | GB8926981D0 (fr) |
HU (1) | HUT52767A (fr) |
IE (1) | IE63047B1 (fr) |
IL (1) | IL92556A (fr) |
NO (1) | NO895086L (fr) |
NZ (1) | NZ231665A (fr) |
PT (1) | PT92699B (fr) |
Families Citing this family (60)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IE64358B1 (en) * | 1989-07-18 | 1995-07-26 | Ici Plc | Diaryl ether heterocycles |
US5254581A (en) * | 1990-06-21 | 1993-10-19 | Imperial Chemical Industries Plc | Pyran derivatives and their use as inhibitors of 5-lipoxygenase |
IE911919A1 (en) * | 1990-06-21 | 1992-01-01 | Zeneca Ltd | Bicyclic heterocyclic compounds |
IE911853A1 (en) * | 1990-06-21 | 1992-01-01 | Ici Plc | Heterocyclene derivatives |
EP0462830B1 (fr) * | 1990-06-21 | 1995-10-18 | Zeneca Limited | Dérivés cycliques d'éther |
GB9113137D0 (en) * | 1990-07-13 | 1991-08-07 | Ici Plc | Thioxo heterocycles |
IE913866A1 (en) * | 1990-11-28 | 1992-06-03 | Ici Plc | Aryl derivatives |
US5272173A (en) * | 1990-11-28 | 1993-12-21 | Imperial Chemical Industries Plc | 5-lipoxygenase inhibitors |
IE914005A1 (en) * | 1990-12-14 | 1992-06-17 | Zeneca Ltd | Novel intermediates |
CA2058254A1 (fr) * | 1991-01-15 | 1992-07-16 | John Francis Kingston | Derives de benzodioxole |
AU645159B2 (en) * | 1991-01-17 | 1994-01-06 | Ici Pharma | Sulphonamide derivatives |
US5258399A (en) * | 1991-01-17 | 1993-11-02 | Imperial Chemical Industries Plc | Sulphonamide derivatives |
US5281720A (en) * | 1991-02-28 | 1994-01-25 | Merck Frosst Canada, Inc. | Pyranylphenyl hydroxyalkylnaphthoic acids as inhibitors of leukotriene biosynthesis |
EP0501578A1 (fr) * | 1991-02-28 | 1992-09-02 | Merck Frosst Canada Inc. | Acides pyranylphényle hydroxyalkylenaphthaléniques et leur utilisation comme inhibiteurs de la biosynthèse de leukotriène |
EP0501579A1 (fr) * | 1991-02-28 | 1992-09-02 | Merck Frosst Canada Inc. | Lactones naphthalèniques comme inhibiteurs de la biosynthèse de leukotriène |
US5227399A (en) * | 1991-02-28 | 1993-07-13 | Merck Frosst Canada, Inc. | Pyranylphenyl naphthalene lactones as inhibitors of leukotriene biosynthesis |
EP0505122A1 (fr) * | 1991-03-21 | 1992-09-23 | Zeneca Limited | Dérivés alpha, alpha-dialkylbenzyle |
EP0532239B1 (fr) * | 1991-09-10 | 1995-12-13 | Zeneca Limited | Dérivés de benzenesulfonamide comme inhibiteurs de 5-lipoxygenase |
EP0540165A1 (fr) * | 1991-10-03 | 1993-05-05 | Zeneca Limited | Dérivés d'acide alcanoique |
EP0555067A1 (fr) * | 1992-02-07 | 1993-08-11 | Zeneca Limited | Dérivés d'hydroxylamine comme inhibiteurs de 5-lipoxygénase |
GB9300894D0 (en) * | 1992-02-07 | 1993-03-10 | Zeneca Ltd | Oxime derivatives |
CA2094465A1 (fr) * | 1992-04-23 | 1993-10-24 | Pierre Andre Raymond Bruneau | Derives de cycloalcane |
CA2095005A1 (fr) * | 1992-05-12 | 1993-11-13 | Philip Neil Edwards | Derives hydroxylamine |
EP0570196B1 (fr) * | 1992-05-12 | 1996-03-06 | Zeneca Limited | Dérivés d'oximes |
CA2095006A1 (fr) * | 1992-05-12 | 1993-11-13 | Philip Neil Edwards | Derives oxime |
EP0570197B1 (fr) * | 1992-05-12 | 1995-12-13 | Zeneca Limited | Dérivés d'hydroxylamine |
US5308852A (en) * | 1992-06-29 | 1994-05-03 | Merck Frosst Canada, Inc. | Heteroarylnaphthalenes as inhibitors of leukotriene biosynthesis |
US5428060A (en) * | 1992-08-27 | 1995-06-27 | Merck Frosst Canada, Inc. | Heteroarylnaphthalene lactones as inhibitors of leukotriene biosynthesis |
US5252599A (en) * | 1992-08-27 | 1993-10-12 | Merck Frosst Canada, Inc. | Heteroarylnaphthalene hydroxy acids as inhibitors of leukotriene biosynthesis |
US5350744A (en) * | 1992-08-27 | 1994-09-27 | Merck Frosst Canada, Inc. | Phenylnaphthalene lactones as inhibitors of leukotriene biosynthesis |
US5426109A (en) * | 1992-08-27 | 1995-06-20 | Merck Frosst Canada, Inc. | Phenylnaphthalene hydroxy acids |
EP0586229A1 (fr) * | 1992-09-01 | 1994-03-09 | Zeneca Limited | 3-Hydroxy-3-(akyl-subst.)-pyrrolidines comme inhibiteur de la 5-lipoxygénase |
AU4444393A (en) * | 1992-09-01 | 1994-03-10 | Zeneca Limited | Pyrrolidine derivatives |
US5354865A (en) * | 1992-09-10 | 1994-10-11 | Abbott Laboratories | Phenylmethyl derivatives having lipoxygenase inhibitory activity |
GR920100426A (el) * | 1992-10-08 | 1994-06-30 | Ici Pharma | Παράγωγα βενζολοσουλφοναμιδίου. |
AP9400632A0 (en) * | 1993-04-29 | 1995-10-07 | Zeneca Ltd | Ether derivatives. |
NZ266541A (en) * | 1993-06-14 | 1997-11-24 | Pfizer | Imidazole derivatives, intermediate compounds and pharmaceutical compositions |
EP0636624A1 (fr) * | 1993-07-27 | 1995-02-01 | Zeneca Limited | Dérivés de thiazole comme inhibiteurs de lipoxygénase |
IL110280A0 (en) * | 1993-07-27 | 1994-10-21 | Zeneca Ltd | Thiazole derivatives |
ZA945250B (en) * | 1993-07-27 | 1995-01-27 | Zeneca Ltd | Thiazole derivatives |
US5407959A (en) * | 1993-11-12 | 1995-04-18 | Abbott Laboratories | (Trans-1,4-dialkoxycyclohexyl) substituted arylalkylaryl-arylalkenylaryl-, and arylalkynylarylurea inhibitors of 5-lipoxygenase |
US5446062A (en) * | 1993-11-12 | 1995-08-29 | Abbott Laboratories | ((4-alkoxypyran-4-yl) substituted) ether, arylalkyl-, arylalkenyl-, and arylalkynyl)urea inhibitors of 5-lipoxygenase |
WO1995026346A1 (fr) * | 1994-03-28 | 1995-10-05 | Pfizer Inc. | Derives benzisothiazoles en tant qu'inhibiteurs de la biosynthese de la 5-lipoxygenase |
WO1995030669A1 (fr) * | 1994-05-06 | 1995-11-16 | Zeneca Limited | Derives ether et compositions pharmaceutiques les contenant |
WO1999023074A1 (fr) * | 1997-11-03 | 1999-05-14 | Aventis Research & Technologies Gmbh & Co. Kg | Derives de naphtalene fluores et leur utilisation dans des melanges a cristaux liquides |
CA2269561C (fr) * | 1998-04-22 | 2007-06-05 | Dainippon Ink And Chemicals, Inc. | Derive de naphtalene et composition a cristaux liquides comprenant celui-ci |
CA2422675A1 (fr) * | 2000-10-03 | 2002-04-11 | Syngenta Participations Ag | Herbicides a base de phenylpropynyloxypyridine |
US6825221B2 (en) | 2001-10-18 | 2004-11-30 | Allergan, Inc. | Arylsulfanyl and heteroarylsulfanyl derivatives for treating pain |
EP1838296B1 (fr) | 2004-10-20 | 2012-08-08 | Resverlogix Corp. | Flavanoides et isoflavanoides pour la prevention et le traitement de maladies cardio-vasculaires |
CA2617213C (fr) | 2005-07-29 | 2014-01-28 | Resverlogix Corp. | Compositions pharmaceutiques pour la prevention et le traitement de maladies complexes et leur administration par des dispositifs medicaux inserables |
SI2118074T1 (sl) | 2007-02-01 | 2014-05-30 | Resverlogix Corp. | Spojine za preprečevanje in zdravljenje kardiovaskularnih bolezni |
PL2346837T3 (pl) | 2008-06-26 | 2015-07-31 | Resverlogix Corp | Sposoby wytwarzania pochodnych chinazolinonu |
US8952021B2 (en) | 2009-01-08 | 2015-02-10 | Resverlogix Corp. | Compounds for the prevention and treatment of cardiovascular disease |
CN105859639A (zh) | 2009-03-18 | 2016-08-17 | 雷斯韦洛吉克斯公司 | 新的抗炎剂 |
SI2421533T1 (sl) | 2009-04-22 | 2019-01-31 | Resverlogix Corp. | Nova protivnetna sredstva |
CN103945848B (zh) | 2011-11-01 | 2016-09-07 | 雷斯韦洛吉克斯公司 | 被取代的喹唑啉酮的口服即释制剂 |
WO2014080290A2 (fr) | 2012-11-21 | 2014-05-30 | Rvx Therapeutics Inc. | Amines cycliques servant d'inhibiteurs de bromodomaines |
WO2014080291A2 (fr) | 2012-11-21 | 2014-05-30 | Rvx Therapeutics Inc. | Dérivés biaryle servant d'inhibiteurs de bromodomaines |
CA2895905A1 (fr) | 2012-12-21 | 2014-06-26 | Zenith Epigenetics Corp. | Nouveaux composes heterocycliques en tant qu'inhibiteurs de bromodomaine |
JO3789B1 (ar) | 2015-03-13 | 2021-01-31 | Resverlogix Corp | التراكيب والوسائل العلاجية المعتمدة لمعالجة الامراض المتعلقة بالمتممة |
Family Cites Families (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA960676A (en) * | 1970-05-21 | 1975-01-07 | Smith Kline And French Canada Ltd. | 3-sulfonamido-4-hydroxyphenyl-2-piperidinylcarbinols |
US3743737A (en) * | 1970-05-21 | 1973-07-03 | Smith Kline French Lab | 3-sulfonamido-4-hydroxyphenyl-2-piperindinylcarbinol compositions |
US3661917A (en) * | 1970-05-21 | 1972-05-09 | Smith Kline French Lab | 3-sulfonamido-4-hydroxyphenyl-2-piperidylcarbinols |
IE56702B1 (en) * | 1982-12-01 | 1991-11-06 | Usv Pharma Corp | Antiinflammatory antiallergic compounds |
GB8306512D0 (en) * | 1983-03-09 | 1983-04-13 | Ici Plc | Heterocyclic compounds |
NO174506B (no) * | 1984-10-30 | 1994-02-07 | Usv Pharma Corp | Analogifremgangsmaate ved fremstilling av terapeutisk aktive forbindelser |
US4625034A (en) * | 1985-02-04 | 1986-11-25 | Usv Pharmaceutical Corp. | 1,2-Dihydro; 1,2,3,4-tetrahydro; 5,8 dihydro; and 5,6,7,8-tetrahydroquinoline derivatives |
US4839369A (en) * | 1985-04-16 | 1989-06-13 | Rorer Pharmaceutical Corporation | Aryl and heteroaryl ethers as agents for the treatment of hypersensitive ailments |
FR2611714A2 (fr) * | 1986-04-23 | 1988-09-09 | Rhone Poulenc Agrochimie | Composes a groupements triazole ou imidazole et tetrahydrofuran, utilisation de ceux-ci a titre de fongicides et procedes de preparation |
EP0271287A3 (fr) * | 1986-12-11 | 1990-06-13 | Merck Frosst Canada Inc. | Acides quinoléine dicarboxyliques et leurs amides |
US4920133A (en) * | 1987-11-03 | 1990-04-24 | Rorer Pharmaceutical Corp. | Quinoline derivatives and use thereof as antagonists of leukotriene D4 |
US4920130A (en) * | 1987-11-02 | 1990-04-24 | Rorer Pharamceutical Corp. | Quinoline derivatives and use thereof as antagonists of leukotriene D4 |
US4920132A (en) * | 1987-11-03 | 1990-04-24 | Rorer Pharmaceutical Corp. | Quinoline derivatives and use thereof as antagonists of leukotriene D4 |
US4920131A (en) * | 1987-11-03 | 1990-04-24 | Rorer Pharmaceutical Corp. | Quinoline derivatives and use thereof as antagonists of leukotriene D4 |
US4918081A (en) * | 1988-06-20 | 1990-04-17 | Rorer Pharmaceutical Corp. | Quinoline derivatives and use thereof as antagonists of leukotriene d4 |
EP0349062A1 (fr) * | 1988-06-27 | 1990-01-03 | Merck Frosst Canada Inc. | Acides quinolineétheralkanoiques |
IE64358B1 (en) * | 1989-07-18 | 1995-07-26 | Ici Plc | Diaryl ether heterocycles |
-
1989
- 1989-11-29 GB GB898926981A patent/GB8926981D0/en active Pending
- 1989-12-05 IE IE388089A patent/IE63047B1/en not_active IP Right Cessation
- 1989-12-05 IL IL9255689A patent/IL92556A/xx not_active IP Right Cessation
- 1989-12-07 NZ NZ231665A patent/NZ231665A/en unknown
- 1989-12-12 AU AU46198/89A patent/AU624663B2/en not_active Ceased
- 1989-12-15 FI FI896014A patent/FI896014A0/fi not_active Application Discontinuation
- 1989-12-15 HU HU896626A patent/HUT52767A/hu unknown
- 1989-12-18 NO NO89895086A patent/NO895086L/no unknown
- 1989-12-20 ES ES89313384T patent/ES2062051T3/es not_active Expired - Lifetime
- 1989-12-20 DE DE89313384T patent/DE68913022T2/de not_active Expired - Fee Related
- 1989-12-20 EP EP89313384A patent/EP0375404B1/fr not_active Expired - Lifetime
- 1989-12-21 DK DK654589A patent/DK654589A/da not_active Application Discontinuation
- 1989-12-21 CA CA002006377A patent/CA2006377A1/fr not_active Abandoned
- 1989-12-22 US US07/455,173 patent/US5098930A/en not_active Expired - Fee Related
- 1989-12-22 PT PT92699A patent/PT92699B/pt not_active IP Right Cessation
- 1989-12-25 JP JP1333012A patent/JPH03135975A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
HUT52767A (en) | 1990-08-28 |
EP0375404B1 (fr) | 1994-02-09 |
NZ231665A (en) | 1992-02-25 |
ES2062051T3 (es) | 1994-12-16 |
US5098930A (en) | 1992-03-24 |
AU624663B2 (en) | 1992-06-18 |
PT92699A (pt) | 1990-06-29 |
DK654589A (da) | 1990-06-24 |
PT92699B (pt) | 1995-09-12 |
CA2006377A1 (fr) | 1990-06-23 |
GB8926981D0 (en) | 1990-01-17 |
IL92556A0 (en) | 1990-08-31 |
AU4619889A (en) | 1990-06-28 |
HU896626D0 (en) | 1990-02-28 |
NO895086L (no) | 1990-06-25 |
DK654589D0 (da) | 1989-12-21 |
DE68913022D1 (de) | 1994-03-24 |
IL92556A (en) | 1994-04-12 |
JPH03135975A (ja) | 1991-06-10 |
DE68913022T2 (de) | 1994-05-11 |
IE893880L (en) | 1990-06-23 |
EP0375404A3 (fr) | 1991-01-16 |
IE63047B1 (en) | 1995-03-22 |
EP0375404A2 (fr) | 1990-06-27 |
NO895086D0 (no) | 1989-12-18 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FA | Application withdrawn |
Owner name: ICI PHARMA Owner name: IMPERIAL CHEMICAL INDUSTRIES PLC |