FI891677A0 - Menetelmä 4-demetoksidaunomysinonin valmistamiseksi - Google Patents

Menetelmä 4-demetoksidaunomysinonin valmistamiseksi

Info

Publication number
FI891677A0
FI891677A0 FI891677A FI891677A FI891677A0 FI 891677 A0 FI891677 A0 FI 891677A0 FI 891677 A FI891677 A FI 891677A FI 891677 A FI891677 A FI 891677A FI 891677 A0 FI891677 A0 FI 891677A0
Authority
FI
Finland
Prior art keywords
demethoxy
group
demethoxydaunomycinone
preparation
demethyldaunomycinone
Prior art date
Application number
FI891677A
Other languages
English (en)
Swedish (sv)
Other versions
FI891677A (fi
FI90411B (fi
FI90411C (fi
Inventor
Walter Cabri
Bernardinis Silvia De
Franco Francalanci
Sergio Penco
Original Assignee
Erba Carlo Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Erba Carlo Spa filed Critical Erba Carlo Spa
Publication of FI891677A0 publication Critical patent/FI891677A0/fi
Publication of FI891677A publication Critical patent/FI891677A/fi
Publication of FI90411B publication Critical patent/FI90411B/fi
Application granted granted Critical
Publication of FI90411C publication Critical patent/FI90411C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C46/00—Preparation of quinones
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
FI891677A 1988-04-11 1989-04-10 Menetelmä 4-demetoksidaunomysinonin valmistamiseksi FI90411C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB888808475A GB8808475D0 (en) 1988-04-11 1988-04-11 Process for preparing 4-demethoxydauno-mycinone
GB8808475 1988-04-11

Publications (4)

Publication Number Publication Date
FI891677A0 true FI891677A0 (fi) 1989-04-10
FI891677A FI891677A (fi) 1989-10-12
FI90411B FI90411B (fi) 1993-10-29
FI90411C FI90411C (fi) 1994-02-10

Family

ID=10634959

Family Applications (1)

Application Number Title Priority Date Filing Date
FI891677A FI90411C (fi) 1988-04-11 1989-04-10 Menetelmä 4-demetoksidaunomysinonin valmistamiseksi

Country Status (27)

Country Link
US (1) US5103029A (fi)
EP (1) EP0337665B1 (fi)
JP (1) JP2746997B2 (fi)
KR (1) KR0136907B1 (fi)
CN (1) CN1024000C (fi)
AT (1) ATE85601T1 (fi)
AU (1) AU604405B2 (fi)
CA (1) CA1337762C (fi)
CZ (1) CZ278973B6 (fi)
DE (1) DE68904797T2 (fi)
DK (1) DK170157B1 (fi)
ES (1) ES2045417T3 (fi)
FI (1) FI90411C (fi)
GB (1) GB8808475D0 (fi)
HU (1) HU201772B (fi)
IE (1) IE63713B1 (fi)
IL (1) IL89879A (fi)
MY (2) MY104427A (fi)
NO (1) NO170213C (fi)
NZ (1) NZ228635A (fi)
PH (1) PH25499A (fi)
PT (1) PT90219B (fi)
RU (1) RU1833361C (fi)
SK (1) SK215289A3 (fi)
UA (1) UA19150A (fi)
YU (1) YU47310B (fi)
ZA (1) ZA892560B (fi)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8803301D0 (en) * 1988-02-12 1988-03-09 Erba Carlo Spa Process for preparation of 4-demethoxy-daunomycinone aglycone of 4-demethoxy-daunorubicin
GB8808475D0 (en) * 1988-04-11 1988-05-11 Erba Carlo Spa Process for preparing 4-demethoxydauno-mycinone
GB8904794D0 (en) * 1989-03-02 1989-04-12 Erba Carlo Spa Process for preparing anthracyclinones
AUPQ319799A0 (en) * 1999-10-01 1999-10-28 Institute Of Drug Technology Australia Limited Chemical methods
IT1318532B1 (it) 2000-05-19 2003-08-27 Antibioticos Spa Procedimento di sintesi di derivati antraciclinici.
JP4688315B2 (ja) * 2001-02-28 2011-05-25 メルシャン株式会社 ４−デメトキシダウノマイシノンの製造
US7053191B2 (en) * 2003-05-21 2006-05-30 Solux Corporation Method of preparing 4-R-substituted 4-demethoxydaunorubicin
DE602005020636D1 (en) * 2004-08-23 2010-05-27 Sicor Inc Synthese von idarubin-aglycon
US8802830B2 (en) * 2005-12-20 2014-08-12 Solux Corporation Synthesis of epirubicin from 13-dihydrodaunorubicine
US8357785B2 (en) * 2008-01-08 2013-01-22 Solux Corporation Method of aralkylation of 4′-hydroxyl group of anthracylins
US8846882B2 (en) 2011-04-29 2014-09-30 Synbias Pharma Ag Method of producing 4-demethoxydaunorubicin
CN107698634B (zh) * 2017-09-22 2020-03-10 南京正大天晴制药有限公司 一种盐酸伊达比星的制备方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4020270A (en) * 1974-05-02 1977-04-26 Societa' Farmaceutici Italia S.P.A. L-lyxohex-1-enopyranose derivative
GB1467383A (en) * 1974-06-12 1977-03-16 Farmaceutici Italia Daunomycin analogues
US4012784A (en) * 1975-11-28 1977-03-15 Minnesota Mining & Manufacturing Company Voice logging recorder including decks dedicated for both logging and recall operations
GB1527050A (en) * 1976-06-19 1978-10-04 Farmaceutici Italia Optically active anthracyclinones
DE2630237A1 (de) * 1976-07-06 1978-01-19 Blaupunkt Werke Gmbh Verfahren zur herstellung von besser abstimmbaren dickschichtwiderstaenden
US4348388A (en) * 1980-04-02 1982-09-07 G.D. Searle & Co. 11-Amino-11-deoxydaunorubicin and analogs
US4495103A (en) * 1982-07-30 1985-01-22 Sumitomo Chemical Company, Ltd. Preparation of optically active 4-demethoxydaunomycinone
GB8803301D0 (en) * 1988-02-12 1988-03-09 Erba Carlo Spa Process for preparation of 4-demethoxy-daunomycinone aglycone of 4-demethoxy-daunorubicin
GB8808475D0 (en) * 1988-04-11 1988-05-11 Erba Carlo Spa Process for preparing 4-demethoxydauno-mycinone
GB8824947D0 (en) * 1988-10-25 1988-11-30 Erba Carlo Spa New 4-substituted anthracyclinones & process for preparing them

Also Published As

Publication number Publication date
RU1833361C (ru) 1993-08-07
KR0136907B1 (ko) 1998-04-25
SK278267B6 (en) 1996-06-05
KR890016058A (ko) 1989-11-28
EP0337665A3 (en) 1990-04-11
ATE85601T1 (de) 1993-02-15
CZ215289A3 (en) 1994-04-13
PT90219A (pt) 1989-11-10
CZ278973B6 (en) 1994-11-16
DK169289D0 (da) 1989-04-07
YU47310B (sh) 1995-01-31
SK215289A3 (en) 1996-06-05
DE68904797T2 (de) 1993-05-27
CA1337762C (en) 1995-12-19
IL89879A (en) 1993-07-08
NZ228635A (en) 1991-03-26
GB8808475D0 (en) 1988-05-11
AU3257289A (en) 1989-10-12
IE63713B1 (en) 1995-05-31
DK169289A (da) 1989-10-12
CN1024000C (zh) 1994-03-16
HUT49624A (en) 1989-10-30
FI891677A (fi) 1989-10-12
FI90411B (fi) 1993-10-29
US5103029A (en) 1992-04-07
MY110352A (en) 1998-04-30
IL89879A0 (en) 1989-12-15
IE891094L (en) 1989-10-11
NO891457L (no) 1989-10-12
EP0337665B1 (en) 1993-02-10
HU201772B (en) 1990-12-28
YU71889A (en) 1991-02-28
UA19150A (uk) 1997-12-25
ZA892560B (en) 1990-12-28
ES2045417T3 (es) 1994-01-16
JPH01308243A (ja) 1989-12-12
PH25499A (en) 1991-07-24
AU604405B2 (en) 1990-12-13
EP0337665A2 (en) 1989-10-18
PT90219B (pt) 1994-07-29
CN1038089A (zh) 1989-12-20
DK170157B1 (da) 1995-06-06
FI90411C (fi) 1994-02-10
MY104427A (en) 1994-03-31
NO170213B (no) 1992-06-15
DE68904797D1 (de) 1993-03-25
NO170213C (no) 1992-09-23
NO891457D0 (no) 1989-04-07
JP2746997B2 (ja) 1998-05-06

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Legal Events

Date Code Title Description
BB Publication of examined application
PC Transfer of assignment of patent

Owner name: PHARMACIA & UPJOHN S.P.A.

FG Patent granted

Owner name: PHARMACIA & UPJOHN S., P.A.

MA Patent expired