FI890388A - Menetelmä (S)-ketoprofeenin valmistamiseksi - Google Patents
Menetelmä (S)-ketoprofeenin valmistamiseksi Download PDFInfo
- Publication number
- FI890388A FI890388A FI890388A FI890388A FI890388A FI 890388 A FI890388 A FI 890388A FI 890388 A FI890388 A FI 890388A FI 890388 A FI890388 A FI 890388A FI 890388 A FI890388 A FI 890388A
- Authority
- FI
- Finland
- Prior art keywords
- preparation
- ketoprofen
- alpha
- arylpropionamides
- phenylpropionamide
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 2
- DKYWVDODHFEZIM-NSHDSACASA-N dexketoprofen Chemical compound OC(=O)[C@@H](C)C1=CC=CC(C(=O)C=2C=CC=CC=2)=C1 DKYWVDODHFEZIM-NSHDSACASA-N 0.000 title 1
- 229960002783 dexketoprofen Drugs 0.000 title 1
- DOZZSWAOPDYVLH-UHFFFAOYSA-N 2-phenylpropanamide Chemical compound NC(=O)C(C)C1=CC=CC=C1 DOZZSWAOPDYVLH-UHFFFAOYSA-N 0.000 abstract 1
- 102000004190 Enzymes Human genes 0.000 abstract 1
- 108090000790 Enzymes Proteins 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 150000007513 acids Chemical class 0.000 abstract 1
- YPGCWEMNNLXISK-UHFFFAOYSA-N alpha-phenylpropionic acid Natural products OC(=O)C(C)C1=CC=CC=C1 YPGCWEMNNLXISK-UHFFFAOYSA-N 0.000 abstract 1
- 230000007062 hydrolysis Effects 0.000 abstract 1
- 238000006460 hydrolysis reaction Methods 0.000 abstract 1
- 244000005700 microbiome Species 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
- C12P7/52—Propionic acid; Butyric acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
- C12P41/006—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by reactions involving C-N bonds, e.g. nitriles, amides, hydantoins, carbamates, lactames, transamination reactions, or keto group formation from racemic mixtures
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Genetics & Genomics (AREA)
- General Chemical & Material Sciences (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Analytical Chemistry (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8800923 | 1988-01-27 | ||
| FR8800923A FR2626288B1 (fi) | 1988-01-27 | 1988-01-27 |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| FI890388A0 FI890388A0 (fi) | 1989-01-26 |
| FI890388A true FI890388A (fi) | 1989-07-28 |
| FI95397B FI95397B (fi) | 1995-10-13 |
| FI95397C FI95397C (fi) | 1996-01-25 |
Family
ID=9362685
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI890388A FI95397C (fi) | 1988-01-27 | 1989-01-26 | Menetelmä (S)-ketoprofeenin valmistamiseksi |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US5089405A (fi) |
| EP (1) | EP0330529B1 (fi) |
| JP (1) | JP2747310B2 (fi) |
| KR (1) | KR890012004A (fi) |
| CN (1) | CN1035847A (fi) |
| AT (1) | ATE87664T1 (fi) |
| AU (1) | AU616933B2 (fi) |
| CA (1) | CA1340524C (fi) |
| DE (1) | DE68905636T2 (fi) |
| DK (1) | DK174729B1 (fi) |
| ES (1) | ES2054039T3 (fi) |
| FI (1) | FI95397C (fi) |
| FR (1) | FR2626288B1 (fi) |
| GR (1) | GR3007536T3 (fi) |
| HU (1) | HU203792B (fi) |
| IE (1) | IE63391B1 (fi) |
| IL (1) | IL89089A (fi) |
| NZ (1) | NZ227742A (fi) |
| PT (1) | PT89553B (fi) |
| RU (1) | RU1806201C (fi) |
| ZA (1) | ZA89641B (fi) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4962124A (en) * | 1987-11-17 | 1990-10-09 | Analgesic Associates | Onset-hastened/enhanced antipyretic response |
| DK314989A (da) * | 1988-06-27 | 1989-12-28 | Asahi Chemical Ind | Fremgangsmaade til fremstilling af optisk aktive alfa-substituerede organiske syrer, samt mikroorganismer og enzymer anvendelige ved fremgangsmaaden |
| EP0356912A3 (en) * | 1988-08-29 | 1991-09-18 | Idemitsu Kosan Company Limited | A method for the preparation of an optically active 2-substituted carboxylic acid |
| US5238828A (en) * | 1988-08-29 | 1993-08-24 | Idemitsu Kosan Company Limited | Method for the preparation of an optically active 2-substituted carboxylic acid |
| DE3910024A1 (de) * | 1989-03-28 | 1990-10-11 | Basf Ag | Verfahren zur fermentativen herstellung von 2-(4-hydroxipenoxi-)propionsaeure |
| FR2655660B1 (fr) * | 1989-12-11 | 1992-03-20 | Rhone Poulenc Sante | Nouveaux polypeptides, sequences d'adn permettant leur expression, procede de preparation et leur utilisation. |
| DK161690D0 (da) * | 1990-07-05 | 1990-07-05 | Novo Nordisk As | Fremgangsmaade til fremstilling af enantiomere forbindelser |
| JP3154721B2 (ja) | 1990-09-20 | 2001-04-09 | イー・アイ・デユポン・ドウ・ヌムール・アンド・カンパニー | エナンチオマー性２−アルカン酸類の製造方法 |
| US5593871A (en) * | 1990-09-20 | 1997-01-14 | E. I. Du Pont De Nemours And Company | Process for the preparation of enantiometric 2-alkanoic acid amides from nitriles |
| SG48037A1 (en) * | 1990-11-14 | 1998-04-17 | Nitto Chemical Industry Co Ltd | Biology process for production-alpha-hydroxyamide or alpha-hydroxy acid |
| FR2669643B1 (fr) * | 1990-11-28 | 1995-04-28 | Rhone Poulenc Chimie | Procede de synthese enzymatique d'adipate d'ammonium. |
| US5258305A (en) * | 1991-09-13 | 1993-11-02 | Nitto Chemical Industry Co., Ltd. | Manufacture of optically active 2-phenylpropionic acid and 2-phenylpropionamide from the nitrile using Rhodococcus equi |
| FR2687915B1 (fr) * | 1992-02-28 | 1995-05-05 | Rhone Poulenc Rorer Sa | Composition pharmaceutique utilisable comme analgesique contenant l'acide (benzoyl-3 phenyl)-2 propionique-(r). |
| US5273895A (en) * | 1992-10-26 | 1993-12-28 | Sepracor, Inc. | Enantioselective production of chiral carboxylic acids |
| EP0703893A1 (en) * | 1993-03-09 | 1996-04-03 | Dompe Farmaceutici S.P.A. | Salts of 2-(3-benzoylphenyl) propionic acid with achiral and chiral organic bases and pharmaceutical compositions thereof |
| US5476965A (en) * | 1994-02-18 | 1995-12-19 | Genencor International, Inc. | Enzymatic resolution of substituted 2-methyl-propionic acid |
| US6214604B1 (en) * | 1995-05-08 | 2001-04-10 | Lonza Ag | Biotechnical production process of piperazine R-α-carboxylic acids and piperazine S-α-carboxylic acid amide |
| US6060265A (en) * | 1996-12-18 | 2000-05-09 | Cytec Technology Corporation | Methods for the detoxification of nitrile and/or amide compounds |
| US5863750A (en) * | 1996-12-18 | 1999-01-26 | Cytec Tech Corp | Methods for the detoxification of nitrile and/or amide compounds |
| CN101892283A (zh) * | 2010-06-03 | 2010-11-24 | 华东理工大学 | 红球菌Rhodococcus ruber 4.1187催化制备光学纯(S)-(+)-2-苯基丙酸 |
| CN103789791B (zh) * | 2014-02-12 | 2016-08-17 | 华东师范大学 | 一种电化学合成具有光学活性的2-苯丙酸方法 |
| CN109486897A (zh) * | 2018-12-04 | 2019-03-19 | 湖南理工学院 | 一种立体选择性酶催化水解拆分2-苯基丙酸对映体的方法 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR1342844A (fr) * | 1961-09-16 | 1963-11-15 | Bayer Ag | Procédé de préparation d'acides phénoxyacétiques substitués, optiquement actifs |
| DE1157237B (de) * | 1961-09-16 | 1963-11-14 | Bayer Ag | Verfahren zur Herstellung von optisch aktiven Phenoxyessigsaeuren |
| JPS4913989A (fi) * | 1972-05-19 | 1974-02-06 | ||
| FR2245585B1 (fi) * | 1973-09-19 | 1976-05-14 | Anvar | |
| JPS5446887A (en) * | 1977-09-19 | 1979-04-13 | Nitto Chem Ind Co Ltd | Preparation of acrylic acid or methacrylic acid |
| FR2447359A1 (fr) * | 1979-01-24 | 1980-08-22 | Anvar | Procede de preparation d'acides a-amines optiquement actifs par hydrolyse biologique de nitriles ou d'amides a-amines |
| US4366250A (en) * | 1980-09-24 | 1982-12-28 | Anvar | Preparation process of optically active α-aminated acids by biological hydrolysis of nitriles |
| NL8400312A (nl) * | 1984-02-02 | 1985-09-02 | Stamicarbon | Optisch aktief gesubstitueerd boterzuuramide alsmede werkwijze voor de optische scheiding van gesubstitueerd boterzuuramide. |
| JPS61162191A (ja) * | 1985-01-11 | 1986-07-22 | Nitto Chem Ind Co Ltd | 微生物による有機酸類の製造法 |
| DK261685A (da) * | 1985-06-11 | 1986-12-12 | Novo Industri As | Fremgangsmaade til fremstilling af optisk aktive, organiske forbindelser |
| AU599944B2 (en) * | 1985-12-20 | 1990-08-02 | Wisconsin Alumni Research Foundation | Process for preparing (S)-alpha-methylarylacetic acids |
| GB8600245D0 (en) * | 1986-01-07 | 1986-02-12 | Shell Int Research | Preparation of 2-arylpropionic acids |
| AU599438B2 (en) * | 1986-12-01 | 1990-07-19 | Gist-Brocades N.V. | Process for the preparation of 2-arylpropionic acids |
| US5229280A (en) * | 1988-02-25 | 1993-07-20 | Istituto Guido Donegani S.P.A. | Process for the continuous biotechnological preparation of optical isomer s(+) of 2-(6-methoxy-2-naphthyl) propionic acid |
-
1988
- 1988-01-27 FR FR8800923A patent/FR2626288B1/fr not_active Expired - Lifetime
-
1989
- 1989-01-25 CN CN89101541A patent/CN1035847A/zh active Pending
- 1989-01-25 EP EP89400197A patent/EP0330529B1/fr not_active Expired - Lifetime
- 1989-01-25 DE DE8989400197T patent/DE68905636T2/de not_active Expired - Lifetime
- 1989-01-25 AT AT89400197T patent/ATE87664T1/de not_active IP Right Cessation
- 1989-01-25 ES ES89400197T patent/ES2054039T3/es not_active Expired - Lifetime
- 1989-01-26 HU HU89340A patent/HU203792B/hu not_active IP Right Cessation
- 1989-01-26 RU SU894613309A patent/RU1806201C/ru active
- 1989-01-26 IL IL89089A patent/IL89089A/xx unknown
- 1989-01-26 DK DK198900338A patent/DK174729B1/da not_active IP Right Cessation
- 1989-01-26 AU AU28828/89A patent/AU616933B2/en not_active Ceased
- 1989-01-26 KR KR1019890000809A patent/KR890012004A/ko not_active Application Discontinuation
- 1989-01-26 IE IE23889A patent/IE63391B1/en not_active IP Right Cessation
- 1989-01-26 NZ NZ227742A patent/NZ227742A/en unknown
- 1989-01-26 FI FI890388A patent/FI95397C/fi not_active IP Right Cessation
- 1989-01-26 JP JP1015207A patent/JP2747310B2/ja not_active Expired - Lifetime
- 1989-01-26 CA CA000589237A patent/CA1340524C/fr not_active Expired - Lifetime
- 1989-01-26 ZA ZA89641A patent/ZA89641B/xx unknown
- 1989-01-27 PT PT89553A patent/PT89553B/pt not_active IP Right Cessation
- 1989-07-26 US US07/385,084 patent/US5089405A/en not_active Expired - Lifetime
-
1993
- 1993-04-01 GR GR920403076T patent/GR3007536T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ES2054039T3 (es) | 1994-08-01 |
| DK33889D0 (da) | 1989-01-26 |
| RU1806201C (ru) | 1993-03-30 |
| NZ227742A (en) | 1991-10-25 |
| ZA89641B (en) | 1989-10-25 |
| PT89553A (pt) | 1989-10-04 |
| AU2882889A (en) | 1989-08-10 |
| FR2626288B1 (fi) | 1990-05-18 |
| KR890012004A (ko) | 1989-08-23 |
| JPH01309695A (ja) | 1989-12-14 |
| FI95397C (fi) | 1996-01-25 |
| EP0330529A1 (fr) | 1989-08-30 |
| EP0330529B1 (fr) | 1993-03-31 |
| IL89089A0 (en) | 1989-08-15 |
| IE890238L (en) | 1989-07-27 |
| DE68905636T2 (de) | 1993-09-23 |
| HUT52821A (en) | 1990-08-28 |
| HU203792B (en) | 1991-09-30 |
| FI95397B (fi) | 1995-10-13 |
| DK174729B1 (da) | 2003-10-06 |
| CN1035847A (zh) | 1989-09-27 |
| IL89089A (en) | 1992-11-15 |
| FI890388A0 (fi) | 1989-01-26 |
| PT89553B (pt) | 1994-02-28 |
| CA1340524C (fr) | 1999-05-04 |
| FR2626288A1 (fi) | 1989-07-28 |
| IE63391B1 (en) | 1995-04-19 |
| DE68905636D1 (de) | 1993-05-06 |
| JP2747310B2 (ja) | 1998-05-06 |
| ATE87664T1 (de) | 1993-04-15 |
| DK33889A (da) | 1989-07-28 |
| AU616933B2 (en) | 1991-11-14 |
| US5089405A (en) | 1992-02-18 |
| GR3007536T3 (fi) | 1993-08-31 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| FI890388A (fi) | Menetelmä (S)-ketoprofeenin valmistamiseksi | |
| GR3008107T3 (fi) | ||
| DE59106289D1 (de) | Verfahren zur Herstellung von Salzen des L-Ornithins. | |
| ATE14597T1 (de) | Verfahren zur enzymatischen herstellung von l-2- amino-4-methylphosphinobuttersaeure. | |
| IE881981L (en) | Process for the preparation of ibuprofen | |
| IE812014L (en) | Esterification | |
| SE8403933D0 (sv) | Production of l-amino acids from alpha-keto acids | |
| ES525463A1 (es) | Procedimiento para la preparacion de acidos alfa-arilalcanoicos | |
| FI880151A (fi) | -glutamyylitranspeptidaasin käyttö glutaryyli-7-amino- tai -ketoadipinyylikefalosporaanihapon entsymaattiseen hydrolysointiin | |
| DE59007810D1 (de) | Verfahren zur enzymatischen Spaltung von 2-Arylpropionsäurevinylestern. | |
| DE68912236D1 (de) | Verfahren zur Herstellung von hochgradig ungesättigten Fettsäuren. | |
| AU581185B2 (en) | Process for the racemization of optically active aminoacids | |
| DE68926521D1 (de) | Verfahren zur Herstellung von optisch aktiver 2-Arylpropionsäure | |
| AU2732388A (en) | A process for the enzymatic hydrolysis of alpha- aminoadipinyl-monoamino compounds | |
| ES2055122T3 (es) | Procedimiento de preparacion de acidos 2-ariloxi- o 2-ariltio-alcanoicos. | |
| ATE49975T1 (de) | Verfahren zur hydrolyse von substituierten methylendiphosphonsauren estern. | |
| JPS57152894A (en) | Preparation of optically active carboxylic acid ester and optically active carboxylic acid | |
| DE68918776D1 (de) | Verfahren zur Herstellung von Biokatalysatoren mit vorher fehlender stereoselektiver Enzymaktivität. |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Patent granted |
Owner name: RHONE-POULENC SANTE |
|
| BB | Publication of examined application | ||
| MM | Patent lapsed |
Owner name: RHONE-POULENC SANTE |