FI884017A - Pyrrolo /1,2-a/ imidazol- och imidazo /1,2-a/-pyridinderivat och anvaendning daerav som inhibitorer av 5-lipoxigenasstigen. - Google Patents

Pyrrolo /1,2-a/ imidazol- och imidazo /1,2-a/-pyridinderivat och anvaendning daerav som inhibitorer av 5-lipoxigenasstigen. Download PDF

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Publication number
FI884017A
FI884017A FI884017A FI884017A FI884017A FI 884017 A FI884017 A FI 884017A FI 884017 A FI884017 A FI 884017A FI 884017 A FI884017 A FI 884017A FI 884017 A FI884017 A FI 884017A
Authority
FI
Finland
Prior art keywords
pyrrolo
imidazo
imidazole
lipoxigenasstigen
som
Prior art date
Application number
FI884017A
Other languages
English (en)
Other versions
FI884017A0 (fi
Inventor
Jerry Leroy Adams
Paul Elliot Bender
John Gerald Gleason
Nabil Hanna
Jr John Frederic Newton
Carl David Perchonock
Kazys Razgaitis
Original Assignee
Smithkline Beckman Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beckman Corp filed Critical Smithkline Beckman Corp
Publication of FI884017A0 publication Critical patent/FI884017A0/fi
Publication of FI884017A publication Critical patent/FI884017A/fi
Priority to FI915918A priority Critical patent/FI915918A0/fi

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic System
    • C07F7/22—Tin compounds
    • C07F7/2208—Compounds having tin linked only to carbon, hydrogen and/or halogen
FI884017A 1987-09-02 1988-08-31 Pyrrolo /1,2-a/ imidazol- och imidazo /1,2-a/-pyridinderivat och anvaendning daerav som inhibitorer av 5-lipoxigenasstigen. FI884017A (fi)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FI915918A FI915918A0 (fi) 1987-09-02 1991-12-16 Foerfarande foer framstaellning av ett 6,7-dihydro-(5h)-pyrrolo(1,2-a)-imidazolderivat och ny mellanprodukt.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US9225887A 1987-09-02 1987-09-02

Publications (2)

Publication Number Publication Date
FI884017A0 FI884017A0 (fi) 1988-08-31
FI884017A true FI884017A (fi) 1989-03-03

Family

ID=22232414

Family Applications (1)

Application Number Title Priority Date Filing Date
FI884017A FI884017A (fi) 1987-09-02 1988-08-31 Pyrrolo /1,2-a/ imidazol- och imidazo /1,2-a/-pyridinderivat och anvaendning daerav som inhibitorer av 5-lipoxigenasstigen.

Country Status (15)

Country Link
EP (1) EP0306300B1 (fi)
JP (1) JPS6471876A (fi)
KR (1) KR900003167A (fi)
CN (1) CN1032011A (fi)
AT (1) ATE122044T1 (fi)
AU (1) AU1815092A (fi)
DE (1) DE3853704D1 (fi)
DK (1) DK483288A (fi)
FI (1) FI884017A (fi)
HU (1) HUT50475A (fi)
IL (1) IL87604A0 (fi)
MY (1) MY103766A (fi)
NO (1) NO883882L (fi)
NZ (1) NZ225967A (fi)
PT (1) PT88390B (fi)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5002941A (en) * 1985-12-12 1991-03-26 Smithkline Beecham Corporation Pyrrolo(1,2-a)imidazole and imidazo(1,2-a)pyridine derivatives and their use as 5-lipoxygenase pathway inhibitors
KR920702621A (ko) * 1989-06-13 1992-10-06 스튜어트 알. 슈터 단핵세포 및/또는 마크로파지에 의한 인터루킨-1 또는 종양회사인자 생성의 억제
PA8595001A1 (es) * 2003-03-04 2004-09-28 Pfizer Prod Inc Nuevos compuestos heteroaromaticos condensados que son inhibidores del factor de crecimiento transforante (tgf)
CN102093366B (zh) * 2011-03-04 2012-11-28 中国医学科学院医药生物技术研究所 双环氨基吡唑类化合物及其在抗柯萨奇病毒中的应用
US10954229B2 (en) 2016-04-08 2021-03-23 Mankind Pharma Ltd. GPR119 agonist compounds
US10526345B2 (en) 2016-04-08 2020-01-07 Mankind Pharma Ltd. Compounds as GPR119 agonists

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4175127A (en) * 1978-09-27 1979-11-20 Smithkline Corporation Pyridyl substituted 2,3-dihydroimidazo[2,1-b]thiazoles
US4186205A (en) * 1979-01-08 1980-01-29 Smithkline Corporation 2,3-Di(4-substituted phenyl)-6,7-dihydro-5H-pyrrolo[1,2-a]imidazoles
ZW24186A1 (en) * 1985-12-12 1987-07-08 Smithkline Beckman Corp Inhibition of the 5-lipoxygenase pathway

Also Published As

Publication number Publication date
DE3853704D1 (de) 1995-06-08
EP0306300A2 (en) 1989-03-08
MY103766A (en) 1993-09-30
AU2174488A (en) 1989-05-25
FI884017A0 (fi) 1988-08-31
DK483288A (da) 1989-03-03
EP0306300A3 (en) 1990-08-16
PT88390A (pt) 1989-07-31
ATE122044T1 (de) 1995-05-15
NO883882D0 (no) 1988-08-31
AU621308B2 (en) 1992-03-12
NZ225967A (en) 1992-03-26
KR900003167A (ko) 1990-03-23
NO883882L (no) 1989-03-03
PT88390B (pt) 1992-10-30
IL87604A0 (en) 1989-01-31
DK483288D0 (da) 1988-08-30
HUT50475A (en) 1990-02-28
AU1815092A (en) 1992-08-27
CN1032011A (zh) 1989-03-29
JPS6471876A (en) 1989-03-16
EP0306300B1 (en) 1995-05-03

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Legal Events

Date Code Title Description
FD Application lapsed
FD Application lapsed

Owner name: SMITHKLINE BECKMAN CORPORATION