IL87604A0 - Pyrrolo(1,2-a)imidazole and pyrrolo(1,2-a)pyridine derivatives and their use as 5-lipoxygenase pathway inhibitors - Google Patents

Pyrrolo(1,2-a)imidazole and pyrrolo(1,2-a)pyridine derivatives and their use as 5-lipoxygenase pathway inhibitors

Info

Publication number
IL87604A0
IL87604A0 IL87604A IL8760488A IL87604A0 IL 87604 A0 IL87604 A0 IL 87604A0 IL 87604 A IL87604 A IL 87604A IL 8760488 A IL8760488 A IL 8760488A IL 87604 A0 IL87604 A0 IL 87604A0
Authority
IL
Israel
Prior art keywords
pyrrolo
imidazole
pathway inhibitors
pyridine derivatives
lipoxygenase pathway
Prior art date
Application number
IL87604A
Other languages
English (en)
Original Assignee
Smithkline Beckman Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beckman Corp filed Critical Smithkline Beckman Corp
Publication of IL87604A0 publication Critical patent/IL87604A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic System
    • C07F7/22—Tin compounds
    • C07F7/2208—Compounds having tin linked only to carbon, hydrogen and/or halogen
IL87604A 1987-09-02 1988-08-30 Pyrrolo(1,2-a)imidazole and pyrrolo(1,2-a)pyridine derivatives and their use as 5-lipoxygenase pathway inhibitors IL87604A0 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US9225887A 1987-09-02 1987-09-02

Publications (1)

Publication Number Publication Date
IL87604A0 true IL87604A0 (en) 1989-01-31

Family

ID=22232414

Family Applications (1)

Application Number Title Priority Date Filing Date
IL87604A IL87604A0 (en) 1987-09-02 1988-08-30 Pyrrolo(1,2-a)imidazole and pyrrolo(1,2-a)pyridine derivatives and their use as 5-lipoxygenase pathway inhibitors

Country Status (15)

Country Link
EP (1) EP0306300B1 (xx)
JP (1) JPS6471876A (xx)
KR (1) KR900003167A (xx)
CN (1) CN1032011A (xx)
AT (1) ATE122044T1 (xx)
AU (1) AU1815092A (xx)
DE (1) DE3853704D1 (xx)
DK (1) DK483288A (xx)
FI (1) FI884017A (xx)
HU (1) HUT50475A (xx)
IL (1) IL87604A0 (xx)
MY (1) MY103766A (xx)
NO (1) NO883882L (xx)
NZ (1) NZ225967A (xx)
PT (1) PT88390B (xx)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5002941A (en) * 1985-12-12 1991-03-26 Smithkline Beecham Corporation Pyrrolo(1,2-a)imidazole and imidazo(1,2-a)pyridine derivatives and their use as 5-lipoxygenase pathway inhibitors
AU6355190A (en) * 1989-06-13 1991-01-17 Smithkline Beecham Corporation Inhibition of interleukin-1 and tumor necrosis factor production by monocytes and/or macrophages
PA8595001A1 (es) * 2003-03-04 2004-09-28 Pfizer Prod Inc Nuevos compuestos heteroaromaticos condensados que son inhibidores del factor de crecimiento transforante (tgf)
CN102093366B (zh) * 2011-03-04 2012-11-28 中国医学科学院医药生物技术研究所 双环氨基吡唑类化合物及其在抗柯萨奇病毒中的应用
US10526345B2 (en) 2016-04-08 2020-01-07 Mankind Pharma Ltd. Compounds as GPR119 agonists
US10954229B2 (en) 2016-04-08 2021-03-23 Mankind Pharma Ltd. GPR119 agonist compounds

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4175127A (en) * 1978-09-27 1979-11-20 Smithkline Corporation Pyridyl substituted 2,3-dihydroimidazo[2,1-b]thiazoles
US4186205A (en) * 1979-01-08 1980-01-29 Smithkline Corporation 2,3-Di(4-substituted phenyl)-6,7-dihydro-5H-pyrrolo[1,2-a]imidazoles
ZW24186A1 (en) * 1985-12-12 1987-07-08 Smithkline Beckman Corp Inhibition of the 5-lipoxygenase pathway

Also Published As

Publication number Publication date
NO883882L (no) 1989-03-03
KR900003167A (ko) 1990-03-23
EP0306300A3 (en) 1990-08-16
FI884017A (fi) 1989-03-03
NO883882D0 (no) 1988-08-31
HUT50475A (en) 1990-02-28
AU2174488A (en) 1989-05-25
MY103766A (en) 1993-09-30
JPS6471876A (en) 1989-03-16
PT88390A (pt) 1989-07-31
ATE122044T1 (de) 1995-05-15
EP0306300A2 (en) 1989-03-08
CN1032011A (zh) 1989-03-29
DK483288A (da) 1989-03-03
AU621308B2 (en) 1992-03-12
DE3853704D1 (de) 1995-06-08
AU1815092A (en) 1992-08-27
FI884017A0 (fi) 1988-08-31
NZ225967A (en) 1992-03-26
DK483288D0 (da) 1988-08-30
EP0306300B1 (en) 1995-05-03
PT88390B (pt) 1992-10-30

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