DE69004389D1 - Heteroarylsubstituierte Imidazo[4,5-c]pyridine. - Google Patents

Heteroarylsubstituierte Imidazo[4,5-c]pyridine.

Info

Publication number
DE69004389D1
DE69004389D1 DE90117520T DE69004389T DE69004389D1 DE 69004389 D1 DE69004389 D1 DE 69004389D1 DE 90117520 T DE90117520 T DE 90117520T DE 69004389 T DE69004389 T DE 69004389T DE 69004389 D1 DE69004389 D1 DE 69004389D1
Authority
DE
Germany
Prior art keywords
pyridines
heteroaryl
substituted imidazo
substituted
relates
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE90117520T
Other languages
English (en)
Other versions
DE69004389T2 (de
Inventor
Ish K Khanna
Richard Mathias Weier
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GD Searle LLC
Original Assignee
GD Searle LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by GD Searle LLC filed Critical GD Searle LLC
Application granted granted Critical
Publication of DE69004389D1 publication Critical patent/DE69004389D1/de
Publication of DE69004389T2 publication Critical patent/DE69004389T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
DE90117520T 1989-09-13 1990-09-11 Heteroarylsubstituierte Imidazo[4,5-c]pyridine. Expired - Fee Related DE69004389T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/406,674 US4990518A (en) 1989-09-13 1989-09-13 Pharmacologically active heteroaryl substituted imidazo (4,5-c) pyridines

Publications (2)

Publication Number Publication Date
DE69004389D1 true DE69004389D1 (de) 1993-12-09
DE69004389T2 DE69004389T2 (de) 1994-03-24

Family

ID=23608994

Family Applications (1)

Application Number Title Priority Date Filing Date
DE90117520T Expired - Fee Related DE69004389T2 (de) 1989-09-13 1990-09-11 Heteroarylsubstituierte Imidazo[4,5-c]pyridine.

Country Status (10)

Country Link
US (1) US4990518A (de)
EP (1) EP0417745B1 (de)
JP (1) JPH03109386A (de)
AT (1) ATE96795T1 (de)
CA (1) CA2025084A1 (de)
DE (1) DE69004389T2 (de)
DK (1) DK0417745T3 (de)
ES (1) ES2059942T3 (de)
IE (1) IE903314A1 (de)
PT (1) PT95296A (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5208242A (en) * 1992-08-26 1993-05-04 G. D. Searle & Co. 5-substituted-4-phenyl-5H-imidazo[4,5-c]pyridine derivatives
US5635514A (en) * 1994-10-25 1997-06-03 G. D. Searle & Company Heteroaralkyl and heteroarylthioalkyl thiophenolic compounds as 5-lipoxgenase inhibitors
WO2002053544A1 (en) * 2000-12-29 2002-07-11 Darwin Discovery Ltd. Pharmaceutical uses and synthesis of nicotinanilide-n-oxides
GB0215293D0 (en) * 2002-07-03 2002-08-14 Rega Foundation Viral inhibitors
ATE544765T1 (de) * 2003-12-22 2012-02-15 Leuven K U Res & Dev Imidazoä4,5-cüpyridinverbindungen und verfahren zur antiviralen behandlung
KR101238430B1 (ko) * 2004-07-27 2013-02-28 길리애드 사이언시즈, 인코포레이티드 이미다조［4,5-ｄ］피리미딘, 그들의 용도 및 제조방법
CA2592388C (en) * 2004-12-21 2013-04-02 Steven S. Bondy Imidazo[4,5-c]pyridine compound and method of antiviral treatment
ES2339298T3 (es) * 2006-07-07 2010-05-18 Gilead Sciences, Inc. Compuesto de piridazina novedoso y uso del mismo.
UA99466C2 (en) 2007-07-06 2012-08-27 Гилиад Сайенсиз, Инк. Crystalline pyridazine compound

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4281005A (en) * 1979-03-05 1981-07-28 Merck & Co., Inc. Novel 2-pyridylimidazole compounds
DE2927987A1 (de) * 1979-07-11 1981-02-05 Thomae Gmbh Dr K Neue 2-alkoxyphenyl-imidazo eckige klammer auf 4,5-b eckige klammer zu pyridine, deren herstellung und deren verwendung als arzneimittel
AT382377B (de) * 1985-04-27 1987-02-25 Beecham Group Plc Verfahren zur herstellung von neuen 7-substituierten aminopyrazolo(4,3-b)pyridinen
US4804658A (en) * 1986-09-15 1989-02-14 G. D. Searle & Co. Imidazopyridine derivatives and pharmaceutical compositions
MY104933A (en) * 1987-09-30 1994-07-30 Pfizer Ltd Platelet activating factor antagonists
US5019581A (en) * 1988-03-14 1991-05-28 G. D. Searle & Co. 5-substituted (4,5-c) imidazopyridine compounds which have useful platelet activating factor antagonistic activity
US4914108A (en) * 1988-03-14 1990-04-03 G. D. Searle & Co. 5-substituted(4,5-c)imidazopyridine compounds which have useful platelet activating factor antagonistic activity

Also Published As

Publication number Publication date
DE69004389T2 (de) 1994-03-24
EP0417745A3 (en) 1991-11-06
PT95296A (pt) 1991-05-22
US4990518A (en) 1991-02-05
CA2025084A1 (en) 1991-03-14
IE903314A1 (en) 1991-04-10
DK0417745T3 (da) 1993-12-13
EP0417745A2 (de) 1991-03-20
ATE96795T1 (de) 1993-11-15
JPH03109386A (ja) 1991-05-09
ES2059942T3 (es) 1994-11-16
EP0417745B1 (de) 1993-11-03

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee