DE69226703D1 - Imidazo (4,5-c)pyridinderivate als paf antagonisten - Google Patents

Imidazo (4,5-c)pyridinderivate als paf antagonisten

Info

Publication number
DE69226703D1
DE69226703D1 DE69226703T DE69226703T DE69226703D1 DE 69226703 D1 DE69226703 D1 DE 69226703D1 DE 69226703 T DE69226703 T DE 69226703T DE 69226703 T DE69226703 T DE 69226703T DE 69226703 D1 DE69226703 D1 DE 69226703D1
Authority
DE
Germany
Prior art keywords
pct
imidazo
pyridine derivatives
paf
paf antagonists
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69226703T
Other languages
English (en)
Other versions
DE69226703T2 (de
Inventor
Mark Whittaker
Andrew Miller
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Vernalis R&D Ltd
Original Assignee
British Biotech Pharmaceuticals Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by British Biotech Pharmaceuticals Ltd filed Critical British Biotech Pharmaceuticals Ltd
Publication of DE69226703D1 publication Critical patent/DE69226703D1/de
Application granted granted Critical
Publication of DE69226703T2 publication Critical patent/DE69226703T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE69226703T 1991-07-24 1992-07-24 Imidazo (4,5-c)pyridinderivate als paf antagonisten Expired - Fee Related DE69226703T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB919116056A GB9116056D0 (en) 1991-07-24 1991-07-24 Compounds
PCT/GB1992/001370 WO1993002080A1 (en) 1991-07-24 1992-07-24 Imidazo (4,5-c) pyridine derivatives as paf antagonists

Publications (2)

Publication Number Publication Date
DE69226703D1 true DE69226703D1 (de) 1998-09-24
DE69226703T2 DE69226703T2 (de) 1999-02-18

Family

ID=10698952

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69226703T Expired - Fee Related DE69226703T2 (de) 1991-07-24 1992-07-24 Imidazo (4,5-c)pyridinderivate als paf antagonisten

Country Status (6)

Country Link
US (1) US5446032A (de)
EP (1) EP0605434B1 (de)
AT (1) ATE169917T1 (de)
DE (1) DE69226703T2 (de)
GB (1) GB9116056D0 (de)
WO (1) WO1993002080A1 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9200209D0 (en) * 1992-01-07 1992-02-26 British Bio Technology Compounds
GB9202791D0 (en) * 1992-02-11 1992-03-25 British Bio Technology Compounds
GB0215293D0 (en) 2002-07-03 2002-08-14 Rega Foundation Viral inhibitors
AR044466A1 (es) * 2003-06-06 2005-09-14 3M Innovative Properties Co Proceso para la preparacion de imidazo [4,5-c] piridin-4-aminas
NZ548074A (en) 2003-12-22 2010-08-27 Gerhard Puerstinger Imidazo[4,5-c]pyridine compounds and methods of antiviral treatment
PT1841765E (pt) * 2004-12-21 2009-05-14 Gilead Sciences Inc Anticorpos para mcp-1 humano
MX2009000235A (es) * 2006-07-07 2009-01-23 Gilead Sciences Inc Compuesto de piridazina novedoso y uso del mismo.
UA99466C2 (en) 2007-07-06 2012-08-27 Гилиад Сайенсиз, Инк. Crystalline pyridazine compound

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4539332A (en) * 1983-11-14 1985-09-03 Merck & Co., Inc. 2,5-Diaryl tetrahydrofurans and analogs thereof as PAF-antagonists
JP2556849B2 (ja) * 1986-02-13 1996-11-27 三共株式会社 グリセリン誘導体
US4804658A (en) * 1986-09-15 1989-02-14 G. D. Searle & Co. Imidazopyridine derivatives and pharmaceutical compositions
US5019581A (en) * 1988-03-14 1991-05-28 G. D. Searle & Co. 5-substituted (4,5-c) imidazopyridine compounds which have useful platelet activating factor antagonistic activity
US4914108A (en) * 1988-03-14 1990-04-03 G. D. Searle & Co. 5-substituted(4,5-c)imidazopyridine compounds which have useful platelet activating factor antagonistic activity
WO1989008653A1 (en) * 1988-03-15 1989-09-21 G.D. Searle & Co. 1H/3H-[4-(N,N-DICYCLOALKYL/BRANCHED-ALKYLCARBOXAMIDO)-BENZYL]IMIDAZO[4,5-c]PYRIDINES AS PAF ANTAGONISTS
GB8904174D0 (en) * 1989-02-23 1989-04-05 British Bio Technology Compounds
PT98673B (pt) * 1990-08-15 1999-01-29 British Bio Technology Processo para a preparacao de compostos que sao antagonistas do factor de activacao de plaquetas por exemplo derivados de benzimidazole e de seus intermediarios

Also Published As

Publication number Publication date
US5446032A (en) 1995-08-29
GB9116056D0 (en) 1991-09-11
EP0605434A1 (de) 1994-07-13
DE69226703T2 (de) 1999-02-18
WO1993002080A1 (en) 1993-02-04
EP0605434B1 (de) 1998-08-19
ATE169917T1 (de) 1998-09-15

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee