FI880813A - Imidazolderivat. - Google Patents

Imidazolderivat. Download PDF

Info

Publication number
FI880813A
FI880813A FI880813A FI880813A FI880813A FI 880813 A FI880813 A FI 880813A FI 880813 A FI880813 A FI 880813A FI 880813 A FI880813 A FI 880813A FI 880813 A FI880813 A FI 880813A
Authority
FI
Finland
Prior art keywords
lower alkyl
hydrogen
formula
residue
prevention
Prior art date
Application number
FI880813A
Other languages
English (en)
Other versions
FI880813A0 (fi
Inventor
Wilhelm Kloetzer
Marc Montavon
Renate Muessner
Nicolas Singewald
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of FI880813A0 publication Critical patent/FI880813A0/fi
Publication of FI880813A publication Critical patent/FI880813A/fi

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C07D233/61Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms with hydrocarbon radicals, substituted by nitrogen atoms not forming part of a nitro radical, attached to ring nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/84Sulfur atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/88Nitrogen atoms, e.g. allantoin
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D249/00Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/081,2,4-Triazoles; Hydrogenated 1,2,4-triazoles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Engineering & Computer Science (AREA)
  • Rheumatology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Epoxy Resins (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
FI880813A 1987-03-20 1988-02-22 Imidazolderivat. FI880813A (fi)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH107387 1987-03-20

Publications (2)

Publication Number Publication Date
FI880813A0 FI880813A0 (fi) 1988-02-22
FI880813A true FI880813A (fi) 1988-09-21

Family

ID=4201822

Family Applications (1)

Application Number Title Priority Date Filing Date
FI880813A FI880813A (fi) 1987-03-20 1988-02-22 Imidazolderivat.

Country Status (23)

Country Link
US (1) US4908363A (fi)
EP (1) EP0283857B1 (fi)
JP (1) JPS63253070A (fi)
KR (1) KR880011117A (fi)
CN (1) CN1016169B (fi)
AT (1) ATE73777T1 (fi)
AU (1) AU613349B2 (fi)
CS (1) CS276093B6 (fi)
DE (1) DE3869163D1 (fi)
DK (1) DK59888A (fi)
ES (1) ES2032482T3 (fi)
FI (1) FI880813A (fi)
GR (1) GR3004729T3 (fi)
HU (1) HU201312B (fi)
IL (1) IL85725A (fi)
MC (1) MC1919A1 (fi)
MX (1) MX10721A (fi)
NO (1) NO170215C (fi)
NZ (1) NZ223862A (fi)
PT (1) PT87025B (fi)
SU (1) SU1657057A3 (fi)
YU (1) YU46444B (fi)
ZA (1) ZA881810B (fi)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5073566A (en) * 1989-11-30 1991-12-17 Eli Lilly And Company Angiotensin ii antagonist 1,3-imidazoles and use thereas
US5612360A (en) * 1992-06-03 1997-03-18 Eli Lilly And Company Angiotensin II antagonists
US5401851A (en) * 1992-06-03 1995-03-28 Eli Lilly And Company Angiotensin II antagonists
US5574057A (en) * 1993-02-03 1996-11-12 University Of Utah Research Foundation Naamidine A extracted from sea sponges and methods for its use as an anti-tumor agent
US5523310A (en) * 1994-12-05 1996-06-04 Hoffmann-La Roche Inc. 1,2,3-triazole derivatives
WO2000031052A1 (en) * 1998-11-23 2000-06-02 F. Hoffmann-La Roche Ag Synthesis of anti-inflammatory [1,2,3]triazoles
DE10132896A1 (de) * 2001-07-06 2003-01-16 Bayer Cropscience Ag Heterocyclische Amidderivate
WO2003010143A1 (en) * 2001-07-26 2003-02-06 Samsung Electronics Co., Ltd. Dialkylhydroxybenzoic acid derivatives containing metal chelating groups and their therapeutic uses
US6737433B1 (en) * 2002-12-16 2004-05-18 Laboratoire Theramex 1-N-phenylamino-1H-imidazole derivatives as aromatase inhibitors and pharmaceutical compositions containing them

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS57501238A (fi) * 1980-07-31 1982-07-15
EP0200947B1 (de) * 1985-04-26 1990-09-12 F. Hoffmann-La Roche Ag 1,3-Disubstituierte Imidazoliumsalze
ZW6687A1 (en) * 1986-05-13 1987-12-02 Hoffmann La Roche 1,3-disubstituted imidazolium salts
MW7087A1 (en) * 1986-10-03 1988-05-11 Hoffmann La Roche 1,3-disubstituted imidazolium salts
AU1543488A (en) * 1987-03-20 1988-10-10 E.I. Du Pont De Nemours And Company Fungicidal aminotriazoles and aminoimidazoles

Also Published As

Publication number Publication date
GR3004729T3 (fi) 1993-04-28
CN1016169B (zh) 1992-04-08
SU1657057A3 (ru) 1991-06-15
NO881199L (no) 1988-09-21
IL85725A (en) 1991-12-12
ATE73777T1 (de) 1992-04-15
NO170215C (no) 1992-09-23
CS8800891A2 (en) 1990-09-12
IL85725A0 (en) 1988-08-31
AU1353288A (en) 1988-09-22
JPS63253070A (ja) 1988-10-20
HUT49581A (en) 1989-10-30
NZ223862A (en) 1990-08-28
CS276093B6 (en) 1992-04-15
MX10721A (es) 1993-09-01
PT87025B (pt) 1992-06-30
YU46444B (sh) 1993-10-20
AU613349B2 (en) 1991-08-01
DK59888A (da) 1988-09-21
US4908363A (en) 1990-03-13
NO881199D0 (no) 1988-03-18
ZA881810B (en) 1988-09-20
PT87025A (pt) 1988-04-01
NO170215B (no) 1992-06-15
ES2032482T3 (es) 1993-02-16
EP0283857A1 (de) 1988-09-28
DE3869163D1 (de) 1992-04-23
YU40388A (en) 1990-02-28
KR880011117A (ko) 1988-10-26
EP0283857B1 (de) 1992-03-18
MC1919A1 (fr) 1989-04-06
CN88101452A (zh) 1988-10-05
FI880813A0 (fi) 1988-02-22
HU201312B (en) 1990-10-28
DK59888D0 (da) 1988-02-05

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Legal Events

Date Code Title Description
FD Application lapsed
FD Application lapsed

Owner name: F. HOFFMANN-LA ROCHE AG