ZA881810B - Imidazole derivatives - Google Patents

Imidazole derivatives

Info

Publication number
ZA881810B
ZA881810B ZA881810A ZA881810A ZA881810B ZA 881810 B ZA881810 B ZA 881810B ZA 881810 A ZA881810 A ZA 881810A ZA 881810 A ZA881810 A ZA 881810A ZA 881810 B ZA881810 B ZA 881810B
Authority
ZA
South Africa
Prior art keywords
lower alkyl
hydrogen
formula
imidazole derivatives
residue
Prior art date
Application number
ZA881810A
Other languages
English (en)
Inventor
Kloetzer Wilhelm
Montavon Marc
Muessner Renate
Singewald Nicolas
Original Assignee
F. Hoffmann-La Roche & Co. Aktiengesellschaft
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F. Hoffmann-La Roche & Co. Aktiengesellschaft filed Critical F. Hoffmann-La Roche & Co. Aktiengesellschaft
Publication of ZA881810B publication Critical patent/ZA881810B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C07D233/61Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms with hydrocarbon radicals, substituted by nitrogen atoms not forming part of a nitro radical, attached to ring nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/84Sulfur atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/88Nitrogen atoms, e.g. allantoin
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D249/00Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/081,2,4-Triazoles; Hydrogenated 1,2,4-triazoles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Engineering & Computer Science (AREA)
  • Rheumatology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Epoxy Resins (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
ZA881810A 1987-03-20 1988-03-14 Imidazole derivatives ZA881810B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH107387 1987-03-20

Publications (1)

Publication Number Publication Date
ZA881810B true ZA881810B (en) 1988-09-20

Family

ID=4201822

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA881810A ZA881810B (en) 1987-03-20 1988-03-14 Imidazole derivatives

Country Status (23)

Country Link
US (1) US4908363A (xx)
EP (1) EP0283857B1 (xx)
JP (1) JPS63253070A (xx)
KR (1) KR880011117A (xx)
CN (1) CN1016169B (xx)
AT (1) ATE73777T1 (xx)
AU (1) AU613349B2 (xx)
CS (1) CS276093B6 (xx)
DE (1) DE3869163D1 (xx)
DK (1) DK59888A (xx)
ES (1) ES2032482T3 (xx)
FI (1) FI880813A (xx)
GR (1) GR3004729T3 (xx)
HU (1) HU201312B (xx)
IL (1) IL85725A (xx)
MC (1) MC1919A1 (xx)
MX (1) MX10721A (xx)
NO (1) NO170215C (xx)
NZ (1) NZ223862A (xx)
PT (1) PT87025B (xx)
SU (1) SU1657057A3 (xx)
YU (1) YU46444B (xx)
ZA (1) ZA881810B (xx)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5073566A (en) * 1989-11-30 1991-12-17 Eli Lilly And Company Angiotensin ii antagonist 1,3-imidazoles and use thereas
US5401851A (en) * 1992-06-03 1995-03-28 Eli Lilly And Company Angiotensin II antagonists
US5612360A (en) * 1992-06-03 1997-03-18 Eli Lilly And Company Angiotensin II antagonists
US5574057A (en) * 1993-02-03 1996-11-12 University Of Utah Research Foundation Naamidine A extracted from sea sponges and methods for its use as an anti-tumor agent
US5523310A (en) * 1994-12-05 1996-06-04 Hoffmann-La Roche Inc. 1,2,3-triazole derivatives
AU1383200A (en) * 1998-11-23 2000-06-13 F. Hoffmann-La Roche Ag Synthesis of anti-inflammatory (1,2,3)triazoles
DE10132896A1 (de) * 2001-07-06 2003-01-16 Bayer Cropscience Ag Heterocyclische Amidderivate
WO2003010143A1 (en) 2001-07-26 2003-02-06 Samsung Electronics Co., Ltd. Dialkylhydroxybenzoic acid derivatives containing metal chelating groups and their therapeutic uses
US6737433B1 (en) * 2002-12-16 2004-05-18 Laboratoire Theramex 1-N-phenylamino-1H-imidazole derivatives as aromatase inhibitors and pharmaceutical compositions containing them

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4457859A (en) * 1980-07-31 1984-07-03 Ivaschenko Alexandr V Mesomorphic material containing 2,2'-azoimidazole compounds containing 1,1'-benzylideneamino substituents
EP0200947B1 (de) * 1985-04-26 1990-09-12 F. Hoffmann-La Roche Ag 1,3-Disubstituierte Imidazoliumsalze
ZW6687A1 (en) * 1986-05-13 1987-12-02 Hoffmann La Roche 1,3-disubstituted imidazolium salts
MW7087A1 (en) * 1986-10-03 1988-05-11 Hoffmann La Roche 1,3-disubstituted imidazolium salts
AU1543488A (en) * 1987-03-20 1988-10-10 E.I. Du Pont De Nemours And Company Fungicidal aminotriazoles and aminoimidazoles

Also Published As

Publication number Publication date
CS276093B6 (en) 1992-04-15
CS8800891A2 (en) 1990-09-12
SU1657057A3 (ru) 1991-06-15
ES2032482T3 (es) 1993-02-16
DE3869163D1 (de) 1992-04-23
NZ223862A (en) 1990-08-28
US4908363A (en) 1990-03-13
IL85725A0 (en) 1988-08-31
GR3004729T3 (xx) 1993-04-28
YU40388A (en) 1990-02-28
KR880011117A (ko) 1988-10-26
NO170215C (no) 1992-09-23
HU201312B (en) 1990-10-28
EP0283857A1 (de) 1988-09-28
NO881199D0 (no) 1988-03-18
AU613349B2 (en) 1991-08-01
YU46444B (sh) 1993-10-20
MC1919A1 (fr) 1989-04-06
PT87025B (pt) 1992-06-30
DK59888D0 (da) 1988-02-05
FI880813A0 (fi) 1988-02-22
ATE73777T1 (de) 1992-04-15
CN88101452A (zh) 1988-10-05
CN1016169B (zh) 1992-04-08
JPS63253070A (ja) 1988-10-20
EP0283857B1 (de) 1992-03-18
IL85725A (en) 1991-12-12
NO170215B (no) 1992-06-15
MX10721A (es) 1993-09-01
PT87025A (pt) 1988-04-01
DK59888A (da) 1988-09-21
AU1353288A (en) 1988-09-22
NO881199L (no) 1988-09-21
HUT49581A (en) 1989-10-30
FI880813A (fi) 1988-09-21

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