SE7614539L - Forfarande for framstellning av karbostyrilderivat med terapeutisk verkan - Google Patents
Forfarande for framstellning av karbostyrilderivat med terapeutisk verkanInfo
- Publication number
- SE7614539L SE7614539L SE7614539A SE7614539A SE7614539L SE 7614539 L SE7614539 L SE 7614539L SE 7614539 A SE7614539 A SE 7614539A SE 7614539 A SE7614539 A SE 7614539A SE 7614539 L SE7614539 L SE 7614539L
- Authority
- SE
- Sweden
- Prior art keywords
- group
- hydrogen atom
- cycloalkylalkanoyl
- phenylalkylcarbonyl
- formula
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/24—Oxygen atoms attached in position 8
- C07D215/26—Alcohols; Ethers thereof
- C07D215/32—Esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/24—Oxygen atoms attached in position 8
- C07D215/26—Alcohols; Ethers thereof
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Quinoline Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP51121423A JPS609713B2 (ja) | 1976-10-08 | 1976-10-08 | カルボスチリル誘導体 |
Publications (2)
Publication Number | Publication Date |
---|---|
SE7614539L true SE7614539L (sv) | 1978-04-09 |
SE434395B SE434395B (sv) | 1984-07-23 |
Family
ID=14810767
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SE7614539A SE434395B (sv) | 1976-10-08 | 1976-12-23 | Analogiforfarande for framstellning av karbostyrilderivat med terapeutisk verkan |
Country Status (10)
Country | Link |
---|---|
US (1) | US4223137A (sv) |
JP (1) | JPS609713B2 (sv) |
BE (1) | BE849794A (sv) |
CA (1) | CA1074801A (sv) |
CH (1) | CH618431A5 (sv) |
DE (1) | DE2658544C2 (sv) |
FR (1) | FR2378521A1 (sv) |
GB (1) | GB1540628A (sv) |
NL (1) | NL174041C (sv) |
SE (1) | SE434395B (sv) |
Families Citing this family (38)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PH17194A (en) * | 1980-03-06 | 1984-06-19 | Otsuka Pharma Co Ltd | Novel carbostyril derivatives,and pharmaceutical composition containing the same |
US4322425A (en) * | 1980-03-14 | 1982-03-30 | Otsuka Pharmaceutical Co., Ltd. | Compositions for treating glaucoma |
FI77852C (sv) * | 1981-02-17 | 1989-05-10 | Otsuka Pharma Co Ltd | Förfarande för framställning av nya, såsom hjärtmediciner användbara s ubstituerade amid- och (mättad heterocykel)karbonylkarbostyrilderivat. |
US4456757A (en) * | 1981-03-20 | 1984-06-26 | Asahi Kasei Kogyo Kabushiki Kaisha | Isoquinolinesulfonyl derivatives and process for the preparation thereof |
DE3276432D1 (en) * | 1981-03-24 | 1987-07-02 | Ciba Geigy Ag | Acyl quinolinone derivatives, processes for their preparation, pharmaceutical compositions containing them and their use |
GB8334494D0 (en) * | 1983-12-24 | 1984-02-01 | Tanabe Seiyaku Co | Carbostyril derivatives |
JPS60173736U (ja) * | 1984-04-25 | 1985-11-18 | 株式会社昭和製作所 | 緩衝器用サブタンク |
JPS61191767A (ja) * | 1985-02-20 | 1986-08-26 | 辻本 夘太郎 | 植物張り家屋 |
JPS62113672A (ja) * | 1985-11-12 | 1987-05-25 | 本田技研工業株式会社 | リヤクツシヨン用リザ−ブタンク |
JPS6348401U (sv) * | 1986-09-17 | 1988-04-01 | ||
JPS63106132A (ja) * | 1986-10-24 | 1988-05-11 | Mazda Motor Corp | 車両のサスペンシヨン装置 |
US4687776A (en) * | 1986-10-24 | 1987-08-18 | Warner-Lambert Company | Drug stabilization |
JPS6374545U (sv) * | 1986-10-31 | 1988-05-18 | ||
JPH0517463Y2 (sv) * | 1987-07-21 | 1993-05-11 | ||
JPS6417047U (sv) * | 1987-07-21 | 1989-01-27 | ||
JPH0518510Y2 (sv) * | 1987-12-28 | 1993-05-17 | ||
US4894219A (en) * | 1988-03-29 | 1990-01-16 | University Of Florida | Beta-agonist carbostyril derivatives, assay method and pharmacological composition |
JPH026831U (sv) * | 1988-06-28 | 1990-01-17 | ||
TWI249515B (en) | 2001-11-13 | 2006-02-21 | Theravance Inc | Aryl aniline beta2 adrenergic receptor agonists |
WO2003042160A1 (en) | 2001-11-13 | 2003-05-22 | Theravance, Inc. | Aryl aniline beta-2 adrenergic receptor agonists |
US20030229058A1 (en) | 2001-11-13 | 2003-12-11 | Moran Edmund J. | Aryl aniline beta2 adrenergic receptor agonists |
US6747043B2 (en) | 2002-05-28 | 2004-06-08 | Theravance, Inc. | Alkoxy aryl β2 adrenergic receptor agonists |
JP2006509790A (ja) * | 2002-11-27 | 2006-03-23 | アルテシアン セラピューティック,インコーポレイティド | 心不全の治療のための混合されたPDE阻害およびβアドレナリン拮抗薬活性または部分的作用薬活性を有する化合物 |
TW200526547A (en) | 2003-09-22 | 2005-08-16 | Theravance Inc | Amino-substituted ethylamino β2 adrenergic receptor agonists |
TW200531692A (en) | 2004-01-12 | 2005-10-01 | Theravance Inc | Aryl aniline derivatives as β2 adrenergic receptor agonists |
FR2869893B1 (fr) * | 2004-05-06 | 2006-07-28 | Rhodia Chimie Sa | Nouveaux granules de phosphates de calcium de type hydroxyapatite, leur procede de preparation et leurs applications |
CA2565243A1 (en) * | 2004-05-13 | 2005-11-24 | Boehringer Ingelheim International Gmbh | Hydroxy-substituted benzo-condensed heterocycles for use as beta agonists in the treatment of respiratory diseases |
US7307076B2 (en) | 2004-05-13 | 2007-12-11 | Boehringer Ingelheim International Gmbh | Beta agonists for the treatment of respiratory diseases |
EP1751086A2 (en) | 2004-06-03 | 2007-02-14 | Theravance, Inc. | DIAMINE ß2 ADRENERGIC RECEPTOR AGONISTS |
JP2008512470A (ja) | 2004-09-10 | 2008-04-24 | セラヴァンス, インコーポレーテッド | アミジン置換アリールアニリン化合物 |
GB0624757D0 (en) * | 2006-12-12 | 2007-01-17 | Sosei R & D Ltd | Novel compounds |
US9090618B2 (en) | 2012-12-27 | 2015-07-28 | Purdue Pharma L.P. | Substituted benzimidazole-type piperidine compounds and uses thereof |
US9784726B2 (en) | 2013-01-08 | 2017-10-10 | Atrogi Ab | Screening method, a kit, a method of treatment and a compound for use in a method of treatment |
GB201714745D0 (en) | 2017-09-13 | 2017-10-25 | Atrogi Ab | New compounds and uses |
GB201714740D0 (en) | 2017-09-13 | 2017-10-25 | Atrogi Ab | New compounds and uses |
GB201714736D0 (en) | 2017-09-13 | 2017-10-25 | Atrogi Ab | New compounds and uses |
GB201714734D0 (en) | 2017-09-13 | 2017-10-25 | Atrogi Ab | New compounds and uses |
GB202205895D0 (en) | 2022-04-22 | 2022-06-08 | Atrogi Ab | New medical uses |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3975391A (en) * | 1973-12-26 | 1976-08-17 | Otsuka Pharmaceutical Company Limited | 5-[1-Hydroxy-2-(substituted-amino)]ethyl-8-hydroxy-3,4-dihydrocarbostyril derivatives |
JPS539227B2 (sv) * | 1973-12-26 | 1978-04-04 | ||
US4022776A (en) * | 1974-01-31 | 1977-05-10 | Otsuka Pharmaceutical Company Limited | 5-[1-Hydroxy-2-(substituted-amino)]ethyl-8-hydroxycarbostyril derivatives |
US4022784A (en) * | 1974-01-31 | 1977-05-10 | Otsuka Pharmaceutical Company Limited | 5-[1-Hydroxy-2-(substituted-amino)]alkyl-8-substituted-carbostyril and -3,4-dihydrocarbostyril derivatives |
US3994901A (en) * | 1974-06-13 | 1976-11-30 | Otsuka Pharmaceutical Company Limited | 5-[1-Hydroxy-2-(substituted-amino)]alkyl-8-hydroxy-3,4-dihydrocarbostyril derivatives |
FI58329C (fi) * | 1974-11-08 | 1981-01-12 | Otsuka Pharma Co Ltd | Foerfarande foer framstaellning av i 8-staellning substituerade 5-(3'-alkylamino-2'-hydroxi)propoxi-3,4-dihydrokarbostyrilderivat |
-
1976
- 1976-10-08 JP JP51121423A patent/JPS609713B2/ja not_active Expired
- 1976-12-23 GB GB53966/76A patent/GB1540628A/en not_active Expired
- 1976-12-23 CA CA268,691A patent/CA1074801A/en not_active Expired
- 1976-12-23 DE DE2658544A patent/DE2658544C2/de not_active Expired
- 1976-12-23 NL NLAANVRAGE7614329,A patent/NL174041C/xx not_active IP Right Cessation
- 1976-12-23 BE BE173581A patent/BE849794A/xx not_active IP Right Cessation
- 1976-12-23 FR FR7638918A patent/FR2378521A1/fr active Granted
- 1976-12-23 SE SE7614539A patent/SE434395B/sv not_active IP Right Cessation
- 1976-12-27 CH CH1634376A patent/CH618431A5/fr not_active IP Right Cessation
-
1978
- 1978-08-10 US US05/932,572 patent/US4223137A/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
FR2378521B1 (sv) | 1979-06-29 |
BE849794A (fr) | 1977-04-15 |
NL174041C (nl) | 1984-04-16 |
CH618431A5 (sv) | 1980-07-31 |
NL7614329A (nl) | 1978-04-11 |
GB1540628A (en) | 1979-02-14 |
FR2378521A1 (fr) | 1978-08-25 |
AU2085576A (en) | 1978-04-06 |
CA1074801A (en) | 1980-04-01 |
DE2658544C2 (de) | 1985-10-03 |
DE2658544A1 (de) | 1978-04-13 |
JPS5346983A (en) | 1978-04-27 |
NL174041B (nl) | 1983-11-16 |
US4223137A (en) | 1980-09-16 |
SE434395B (sv) | 1984-07-23 |
JPS609713B2 (ja) | 1985-03-12 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
NUG | Patent has lapsed |
Ref document number: 7614539-0 Effective date: 19910704 Format of ref document f/p: F |