CH618431A5 - - Google Patents
Download PDFInfo
- Publication number
- CH618431A5 CH618431A5 CH1634376A CH1634376A CH618431A5 CH 618431 A5 CH618431 A5 CH 618431A5 CH 1634376 A CH1634376 A CH 1634376A CH 1634376 A CH1634376 A CH 1634376A CH 618431 A5 CH618431 A5 CH 618431A5
- Authority
- CH
- Switzerland
- Prior art keywords
- group
- compound
- carbostyril
- formula
- hydroxy
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/24—Oxygen atoms attached in position 8
- C07D215/26—Alcohols; Ethers thereof
- C07D215/32—Esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/24—Oxygen atoms attached in position 8
- C07D215/26—Alcohols; Ethers thereof
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Quinoline Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP51121423A JPS609713B2 (ja) | 1976-10-08 | 1976-10-08 | カルボスチリル誘導体 |
Publications (1)
Publication Number | Publication Date |
---|---|
CH618431A5 true CH618431A5 (sv) | 1980-07-31 |
Family
ID=14810767
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CH1634376A CH618431A5 (sv) | 1976-10-08 | 1976-12-27 |
Country Status (10)
Country | Link |
---|---|
US (1) | US4223137A (sv) |
JP (1) | JPS609713B2 (sv) |
BE (1) | BE849794A (sv) |
CA (1) | CA1074801A (sv) |
CH (1) | CH618431A5 (sv) |
DE (1) | DE2658544C2 (sv) |
FR (1) | FR2378521A1 (sv) |
GB (1) | GB1540628A (sv) |
NL (1) | NL174041C (sv) |
SE (1) | SE434395B (sv) |
Families Citing this family (38)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PH17194A (en) * | 1980-03-06 | 1984-06-19 | Otsuka Pharma Co Ltd | Novel carbostyril derivatives,and pharmaceutical composition containing the same |
US4322425A (en) * | 1980-03-14 | 1982-03-30 | Otsuka Pharmaceutical Co., Ltd. | Compositions for treating glaucoma |
FI77852C (sv) * | 1981-02-17 | 1989-05-10 | Otsuka Pharma Co Ltd | Förfarande för framställning av nya, såsom hjärtmediciner användbara s ubstituerade amid- och (mättad heterocykel)karbonylkarbostyrilderivat. |
US4456757A (en) * | 1981-03-20 | 1984-06-26 | Asahi Kasei Kogyo Kabushiki Kaisha | Isoquinolinesulfonyl derivatives and process for the preparation thereof |
DE3276432D1 (en) * | 1981-03-24 | 1987-07-02 | Ciba Geigy Ag | Acyl quinolinone derivatives, processes for their preparation, pharmaceutical compositions containing them and their use |
GB8334494D0 (en) * | 1983-12-24 | 1984-02-01 | Tanabe Seiyaku Co | Carbostyril derivatives |
JPS60173736U (ja) * | 1984-04-25 | 1985-11-18 | 株式会社昭和製作所 | 緩衝器用サブタンク |
JPS61191767A (ja) * | 1985-02-20 | 1986-08-26 | 辻本 夘太郎 | 植物張り家屋 |
JPS62113672A (ja) * | 1985-11-12 | 1987-05-25 | 本田技研工業株式会社 | リヤクツシヨン用リザ−ブタンク |
JPS6348401U (sv) * | 1986-09-17 | 1988-04-01 | ||
JPS63106132A (ja) * | 1986-10-24 | 1988-05-11 | Mazda Motor Corp | 車両のサスペンシヨン装置 |
US4687776A (en) * | 1986-10-24 | 1987-08-18 | Warner-Lambert Company | Drug stabilization |
JPS6374545U (sv) * | 1986-10-31 | 1988-05-18 | ||
JPH0517463Y2 (sv) * | 1987-07-21 | 1993-05-11 | ||
JPS6417047U (sv) * | 1987-07-21 | 1989-01-27 | ||
JPH0518510Y2 (sv) * | 1987-12-28 | 1993-05-17 | ||
US4894219A (en) * | 1988-03-29 | 1990-01-16 | University Of Florida | Beta-agonist carbostyril derivatives, assay method and pharmacological composition |
JPH026831U (sv) * | 1988-06-28 | 1990-01-17 | ||
TWI249515B (en) | 2001-11-13 | 2006-02-21 | Theravance Inc | Aryl aniline beta2 adrenergic receptor agonists |
WO2003042160A1 (en) | 2001-11-13 | 2003-05-22 | Theravance, Inc. | Aryl aniline beta-2 adrenergic receptor agonists |
US20030229058A1 (en) | 2001-11-13 | 2003-12-11 | Moran Edmund J. | Aryl aniline beta2 adrenergic receptor agonists |
US6747043B2 (en) | 2002-05-28 | 2004-06-08 | Theravance, Inc. | Alkoxy aryl β2 adrenergic receptor agonists |
JP2006509790A (ja) * | 2002-11-27 | 2006-03-23 | アルテシアン セラピューティック,インコーポレイティド | 心不全の治療のための混合されたPDE阻害およびβアドレナリン拮抗薬活性または部分的作用薬活性を有する化合物 |
TW200526547A (en) | 2003-09-22 | 2005-08-16 | Theravance Inc | Amino-substituted ethylamino β2 adrenergic receptor agonists |
TW200531692A (en) | 2004-01-12 | 2005-10-01 | Theravance Inc | Aryl aniline derivatives as β2 adrenergic receptor agonists |
FR2869893B1 (fr) * | 2004-05-06 | 2006-07-28 | Rhodia Chimie Sa | Nouveaux granules de phosphates de calcium de type hydroxyapatite, leur procede de preparation et leurs applications |
CA2565243A1 (en) * | 2004-05-13 | 2005-11-24 | Boehringer Ingelheim International Gmbh | Hydroxy-substituted benzo-condensed heterocycles for use as beta agonists in the treatment of respiratory diseases |
US7307076B2 (en) | 2004-05-13 | 2007-12-11 | Boehringer Ingelheim International Gmbh | Beta agonists for the treatment of respiratory diseases |
EP1751086A2 (en) | 2004-06-03 | 2007-02-14 | Theravance, Inc. | DIAMINE ß2 ADRENERGIC RECEPTOR AGONISTS |
JP2008512470A (ja) | 2004-09-10 | 2008-04-24 | セラヴァンス, インコーポレーテッド | アミジン置換アリールアニリン化合物 |
GB0624757D0 (en) * | 2006-12-12 | 2007-01-17 | Sosei R & D Ltd | Novel compounds |
US9090618B2 (en) | 2012-12-27 | 2015-07-28 | Purdue Pharma L.P. | Substituted benzimidazole-type piperidine compounds and uses thereof |
US9784726B2 (en) | 2013-01-08 | 2017-10-10 | Atrogi Ab | Screening method, a kit, a method of treatment and a compound for use in a method of treatment |
GB201714745D0 (en) | 2017-09-13 | 2017-10-25 | Atrogi Ab | New compounds and uses |
GB201714740D0 (en) | 2017-09-13 | 2017-10-25 | Atrogi Ab | New compounds and uses |
GB201714736D0 (en) | 2017-09-13 | 2017-10-25 | Atrogi Ab | New compounds and uses |
GB201714734D0 (en) | 2017-09-13 | 2017-10-25 | Atrogi Ab | New compounds and uses |
GB202205895D0 (en) | 2022-04-22 | 2022-06-08 | Atrogi Ab | New medical uses |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3975391A (en) * | 1973-12-26 | 1976-08-17 | Otsuka Pharmaceutical Company Limited | 5-[1-Hydroxy-2-(substituted-amino)]ethyl-8-hydroxy-3,4-dihydrocarbostyril derivatives |
JPS539227B2 (sv) * | 1973-12-26 | 1978-04-04 | ||
US4022776A (en) * | 1974-01-31 | 1977-05-10 | Otsuka Pharmaceutical Company Limited | 5-[1-Hydroxy-2-(substituted-amino)]ethyl-8-hydroxycarbostyril derivatives |
US4022784A (en) * | 1974-01-31 | 1977-05-10 | Otsuka Pharmaceutical Company Limited | 5-[1-Hydroxy-2-(substituted-amino)]alkyl-8-substituted-carbostyril and -3,4-dihydrocarbostyril derivatives |
US3994901A (en) * | 1974-06-13 | 1976-11-30 | Otsuka Pharmaceutical Company Limited | 5-[1-Hydroxy-2-(substituted-amino)]alkyl-8-hydroxy-3,4-dihydrocarbostyril derivatives |
FI58329C (fi) * | 1974-11-08 | 1981-01-12 | Otsuka Pharma Co Ltd | Foerfarande foer framstaellning av i 8-staellning substituerade 5-(3'-alkylamino-2'-hydroxi)propoxi-3,4-dihydrokarbostyrilderivat |
-
1976
- 1976-10-08 JP JP51121423A patent/JPS609713B2/ja not_active Expired
- 1976-12-23 GB GB53966/76A patent/GB1540628A/en not_active Expired
- 1976-12-23 CA CA268,691A patent/CA1074801A/en not_active Expired
- 1976-12-23 DE DE2658544A patent/DE2658544C2/de not_active Expired
- 1976-12-23 NL NLAANVRAGE7614329,A patent/NL174041C/xx not_active IP Right Cessation
- 1976-12-23 BE BE173581A patent/BE849794A/xx not_active IP Right Cessation
- 1976-12-23 FR FR7638918A patent/FR2378521A1/fr active Granted
- 1976-12-23 SE SE7614539A patent/SE434395B/sv not_active IP Right Cessation
- 1976-12-27 CH CH1634376A patent/CH618431A5/fr not_active IP Right Cessation
-
1978
- 1978-08-10 US US05/932,572 patent/US4223137A/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
FR2378521B1 (sv) | 1979-06-29 |
BE849794A (fr) | 1977-04-15 |
NL174041C (nl) | 1984-04-16 |
NL7614329A (nl) | 1978-04-11 |
GB1540628A (en) | 1979-02-14 |
FR2378521A1 (fr) | 1978-08-25 |
AU2085576A (en) | 1978-04-06 |
CA1074801A (en) | 1980-04-01 |
DE2658544C2 (de) | 1985-10-03 |
DE2658544A1 (de) | 1978-04-13 |
JPS5346983A (en) | 1978-04-27 |
NL174041B (nl) | 1983-11-16 |
US4223137A (en) | 1980-09-16 |
SE434395B (sv) | 1984-07-23 |
SE7614539L (sv) | 1978-04-09 |
JPS609713B2 (ja) | 1985-03-12 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CH618431A5 (sv) | ||
CH653021A5 (fr) | Derives piperidino, piperazino et homopiperazino, n-substitues par un groupe heterocyclique aromatique, leur procede de preparation et composition therapeutique les contenant. | |
EP0031753B1 (fr) | Nouveaux dérivés de la (pipéridyl-4)-2 (quinolyl-4)-1 éthanone, produits intermédiaires et procédés pour leur préparation, et leur utilisation comme médicaments | |
EP0053964B1 (fr) | Médicaments à base de dérivés de (quinolyl-4)-1 éthanol ou propanol, nouveaux dérivés de (quinolyl-4)-1 éthanol ou propanol et procédés pour leur préparation | |
EP0089894B1 (fr) | (Benzimidazolyl-1)-1,N-((hydroxy-4 méthoxy-3 phényl)-2 hydroxy-2 éthyl) amino-3 butane et ses sels et hydrates à activité bêta-adrénergique, leurs applications thérapeutiques, et procédé pour les préparer | |
EP0028959B1 (fr) | Dérivés de la 5,8,13,13a-tétrahydro-6H-dibenzo (a,g) quinolizine, procédé d'obtention et compositions pharmaceutiques les contenant | |
CH630629A5 (fr) | Derives de la morphine, leur procede de preparation et leur application comme medicament. | |
CH619453A5 (sv) | ||
EP0173585B1 (fr) | Médicaments à base de dérivés de la pipéridine, nouveaux dérivés de la pipéridine et leurs procédés de préparation | |
JPH0578554B2 (sv) | ||
EP0005091B1 (fr) | Nouvelles pipérazines monosubstituées, leurs procédés de préparation et les compositions pharmaceutiques les renfermant | |
US3091638A (en) | N, n'-disubstituted hydrazine derivatives | |
FR3067711A1 (fr) | Inhibiteurs de la catechol-o-methyl-transferase (comt) | |
WO2001044197A2 (fr) | Derives de 2-phenyl-quinoleine et leur utilisation en tant qu'agent contractant des muscles lisses | |
BE852556A (fr) | Derives de carbostyrile et leur procede de preparation | |
FR2522663A1 (fr) | Nouveaux alcaloides ergopeptidiques, leur preparation et leur utilisation comme medicaments | |
CH616156A5 (sv) | ||
CA1217724A (fr) | Compositions pharmaceutiques utiles comme antiarythmiques | |
KR800000542B1 (ko) | 아미노-페닐-에탄올아민의 제조방법 | |
EP0155888A1 (fr) | Dérivés de (quinol yl-4)-1 (piperidyl-4)-2 ethanamine et de (quinolyl-4)-1 (piperidyl-4)-3 propanamine, procédés pour leur préparation et médicaments les contenant | |
CH638210A5 (fr) | Ester derive de l'acide quinolopyranne-4-one-2-carboxylique, procede de sa preparation et utilisation de cet ester comme compose actif dans un medicament antiallergique pour le traitement de l'asthme. | |
EP2938595B1 (fr) | Procede de synthese d'une hydrazine utile dans le traitement du virus du papillome | |
CA1116089A (fr) | Compositions pharmaceutiques comprenant des medicaments a base de derives de la quinoleine | |
EP0078735B1 (fr) | Nouveaux dérivés appartenant à la famille des 3-amino-1-hétéroaryloxy-2-propanols, utilisation en thérapeutique et procédé de préparation | |
KR850000031B1 (ko) | 사이클로알카[4,5]피롤로[2,3-g]-이소퀴놀린의 제조방법 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PL | Patent ceased |