FI875353A - Cytostatiskt verkande antracyklinderivat. - Google Patents

Cytostatiskt verkande antracyklinderivat. Download PDF

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Publication number
FI875353A
FI875353A FI875353A FI875353A FI875353A FI 875353 A FI875353 A FI 875353A FI 875353 A FI875353 A FI 875353A FI 875353 A FI875353 A FI 875353A FI 875353 A FI875353 A FI 875353A
Authority
FI
Finland
Prior art keywords
cytostatiskt
antracyklinderivat
verkande
inorganic
salt
Prior art date
Application number
FI875353A
Other languages
English (en)
Other versions
FI89495B (fi
FI89495C (fi
FI875353A0 (fi
Inventor
Peter Hermentin
Michael Paal
Hans Peter Kraemer
Cenek Kolar
Dieter Hoffmann
Manfred Gerken
Hans Gerd Berscheid
Dirk Boettger
Original Assignee
Behringwerke Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Behringwerke Ag filed Critical Behringwerke Ag
Publication of FI875353A0 publication Critical patent/FI875353A0/fi
Publication of FI875353A publication Critical patent/FI875353A/fi
Publication of FI89495B publication Critical patent/FI89495B/fi
Application granted granted Critical
Publication of FI89495C publication Critical patent/FI89495C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Vibration Dampers (AREA)
  • Treatments For Attaching Organic Compounds To Fibrous Goods (AREA)
  • Paper (AREA)
FI875353A 1986-12-08 1987-12-04 Foerfarande foer framstaellning av cytostatiskt verkande antracyklinderivat FI89495C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19863641833 DE3641833A1 (de) 1986-12-08 1986-12-08 Zytostatisch wirksame anthracyclinderivate
DE3641833 1986-12-08

Publications (4)

Publication Number Publication Date
FI875353A0 FI875353A0 (fi) 1987-12-04
FI875353A true FI875353A (fi) 1988-06-09
FI89495B FI89495B (fi) 1993-06-30
FI89495C FI89495C (fi) 1993-10-11

Family

ID=6315675

Family Applications (1)

Application Number Title Priority Date Filing Date
FI875353A FI89495C (fi) 1986-12-08 1987-12-04 Foerfarande foer framstaellning av cytostatiskt verkande antracyklinderivat

Country Status (11)

Country Link
US (1) US4948880A (fi)
EP (1) EP0270992B1 (fi)
JP (1) JP2579654B2 (fi)
AT (1) ATE106890T1 (fi)
AU (1) AU613327B2 (fi)
CA (1) CA1340422C (fi)
DE (2) DE3641833A1 (fi)
DK (1) DK170752B1 (fi)
ES (1) ES2056808T3 (fi)
FI (1) FI89495C (fi)
PT (1) PT86314B (fi)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0822869B2 (ja) * 1986-06-25 1996-03-06 ヘキストジヤパン株式会社 サイトロジンｓ誘導体およびそれを含有する抗癌剤
DE3706175A1 (de) * 1987-02-26 1988-09-08 Behringwerke Ag Verwendung von lipophilen anthracyclinen zur behandlung "sekundaer" anthracyclin-resistenter tumoren, mittel enthaltend ein lipophiles anthracyclin und verfahren zu seiner herstellung
DE3712350A1 (de) * 1987-04-11 1988-10-20 Behringwerke Ag Semisynthetische rhodomycine, verfahren zu ihrer herstellung und ihre verwendung als zytostatika
DE3733885A1 (de) * 1987-10-07 1989-04-27 Hoechst Ag Neue anthracyclin-derivate, ein verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
DE3819092A1 (de) * 1988-06-04 1989-12-14 Behringwerke Ag Zytostatisch wirksame anthracyclinderivate
DE3822220A1 (de) * 1988-07-01 1990-01-04 Behringwerke Ag Modifizierte rhodomycine, verfahren zu ihrer herstellung und ihre verwendung
DE3836122A1 (de) * 1988-10-22 1990-05-31 Behringwerke Ag Verfahren zur herstellung von 4-0-alkyl-rhodomycinen
DE3842836A1 (de) * 1988-12-20 1990-06-21 Behringwerke Ag Rhodomycine mit einer modifizierten kohlenhydrat-einheit
JP2779652B2 (ja) * 1988-12-27 1998-07-23 武田薬品工業株式会社 生理活性物質ｔａｎ―１１２０，その還元体，それらの製造法および用途ならびに微生物
DE4036155A1 (de) * 1990-11-14 1992-05-21 Behringwerke Ag Semisynthetische diastereomerenreine n-glycidyl-anthracycline, verfahren zu ihrer stereoselektiven herstellung und ihre verwendung als zytostatika
IT1262565B (it) * 1993-09-30 1996-07-04 Menarini Farma Ind Disaccaridi di antracicline, loro processi di preparazione e composizioni farmaceutiche che li contengono.
US6677309B1 (en) 1997-04-11 2004-01-13 University Technology Corporation Anti-cancer drug aldehyde conjugate drugs with enhanced cytotoxicity compounds, compositions and methods
US5948896A (en) * 1997-08-13 1999-09-07 Gem Pharmaceuticals Processes for preparing 13-deoxy anthracycline derivatives
SE0401066D0 (sv) * 2004-04-22 2004-04-22 Stefan Sjoeberg Chemical Derivatives

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL176004C (nl) * 1976-10-05 1985-02-01 Microbial Chem Res Found Werkwijze ter bereiding van geneesmiddelen met antitumorwerking op basis van anthracycline glycosiden en werkwijze ter bereiding van daartoe dienende anthracycline glycosiden.
JPS54141759A (en) * 1978-04-24 1979-11-05 Microbial Chem Res Found Novel anthracycline derivative
JPS6023679B2 (ja) * 1979-07-13 1985-06-08 メルシャン株式会社 ロドマイシン群抗生物質とその製造法
JPS57176995A (en) * 1981-04-23 1982-10-30 Sanraku Inc Novel anthracyclinone glycoside and its preparation
DE3325957A1 (de) * 1983-07-19 1985-02-07 Hoechst Ag, 6230 Frankfurt Anthracyclin-derivate, ein verfahren zu ihrer herstellung und ihre verwendung als cytostatika
US4591637A (en) * 1985-01-17 1986-05-27 Sri International Open chain-morpholino adriamycins
JPS62207293A (ja) * 1986-03-07 1987-09-11 Sapporo Breweries Ltd 新規アンスラサイクリン抗生物質とその製造法

Also Published As

Publication number Publication date
EP0270992B1 (de) 1994-06-08
EP0270992A3 (en) 1988-10-12
EP0270992A2 (de) 1988-06-15
DK170752B1 (da) 1996-01-08
DK640587A (da) 1988-06-09
AU8213487A (en) 1988-06-09
AU613327B2 (en) 1991-08-01
CA1340422C (en) 1999-03-09
JPS63145295A (ja) 1988-06-17
ATE106890T1 (de) 1994-06-15
DE3750025D1 (de) 1994-07-14
FI89495B (fi) 1993-06-30
PT86314B (pt) 1990-11-07
FI89495C (fi) 1993-10-11
JP2579654B2 (ja) 1997-02-05
PT86314A (de) 1988-01-01
ES2056808T3 (es) 1994-10-16
FI875353A0 (fi) 1987-12-04
DK640587D0 (da) 1987-12-07
US4948880A (en) 1990-08-14
DE3641833A1 (de) 1988-06-09

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Legal Events

Date Code Title Description
BB Publication of examined application
FG Patent granted

Owner name: BEHRINGWERKE AKTIENGESELLSCHAFT

MA Patent expired