FI872015A - Foerfarande foer framstaellning av farmaceutiskt anvaendbara styrylpyrazoler och -isoxazoler samt deras analoger. - Google Patents
Foerfarande foer framstaellning av farmaceutiskt anvaendbara styrylpyrazoler och -isoxazoler samt deras analoger. Download PDFInfo
- Publication number
- FI872015A FI872015A FI872015A FI872015A FI872015A FI 872015 A FI872015 A FI 872015A FI 872015 A FI872015 A FI 872015A FI 872015 A FI872015 A FI 872015A FI 872015 A FI872015 A FI 872015A
- Authority
- FI
- Finland
- Prior art keywords
- styrylpyrazoler
- isoxazoler
- farmaceutiskt
- analoger
- anvaendbara
- Prior art date
Links
- 101100148710 Clarkia breweri SAMT gene Proteins 0.000 title 1
- 102000001381 Arachidonate 5-Lipoxygenase Human genes 0.000 abstract 1
- 108010093579 Arachidonate 5-lipoxygenase Proteins 0.000 abstract 1
- 102000004005 Prostaglandin-endoperoxide synthases Human genes 0.000 abstract 1
- 108090000459 Prostaglandin-endoperoxide synthases Proteins 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 150000003854 isothiazoles Chemical class 0.000 abstract 1
- 150000002545 isoxazoles Chemical class 0.000 abstract 1
- 150000003217 pyrazoles Chemical class 0.000 abstract 1
- 230000000475 sunscreen effect Effects 0.000 abstract 1
- 239000000516 sunscreening agent Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
- C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
- C07D261/06—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D275/00—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings
- C07D275/02—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings not condensed with other rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
- C07F7/1804—Compounds having Si-O-C linkages
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6527—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having nitrogen and oxygen atoms as the only ring hetero atoms
- C07F9/653—Five-membered rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pulmonology (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Plural Heterocyclic Compounds (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US86117986A | 1986-05-09 | 1986-05-09 | |
US91069286A | 1986-09-22 | 1986-09-22 | |
US3273087A | 1987-04-06 | 1987-04-06 |
Publications (2)
Publication Number | Publication Date |
---|---|
FI872015A0 FI872015A0 (fi) | 1987-05-06 |
FI872015A true FI872015A (fi) | 1987-11-10 |
Family
ID=27364200
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FI872015A FI872015A (fi) | 1986-05-09 | 1987-05-06 | Foerfarande foer framstaellning av farmaceutiskt anvaendbara styrylpyrazoler och -isoxazoler samt deras analoger. |
Country Status (15)
Country | Link |
---|---|
US (1) | US5208251A (fi) |
EP (1) | EP0245825B1 (fi) |
JP (1) | JP2656035B2 (fi) |
KR (1) | KR870011113A (fi) |
AT (1) | ATE61582T1 (fi) |
AU (1) | AU613579B2 (fi) |
DE (1) | DE3768553D1 (fi) |
DK (1) | DK175824B1 (fi) |
ES (1) | ES2037681T3 (fi) |
FI (1) | FI872015A (fi) |
GR (1) | GR3001831T3 (fi) |
IE (1) | IE59813B1 (fi) |
NO (1) | NO871917L (fi) |
NZ (1) | NZ220248A (fi) |
PT (1) | PT84840B (fi) |
Families Citing this family (36)
Publication number | Priority date | Publication date | Assignee | Title |
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IL91418A (en) * | 1988-09-01 | 1997-11-20 | Rhone Poulenc Agrochimie | (hetero) cyclic amide derivatives, process for their preparation and fungicidal compositions containing them |
DE3923649A1 (de) * | 1989-07-18 | 1991-01-31 | Hoechst Ag | Neue pyrazoline und ihre verwendung als safener |
GB8920519D0 (en) * | 1989-09-11 | 1989-10-25 | Rhone Poulenc Ltd | New compositions of matter |
DE3939010A1 (de) * | 1989-11-25 | 1991-05-29 | Hoechst Ag | Isoxazoline, verfahren zu ihrer herstellung und ihre verwendung als pflanzenschuetzende mittel |
US5324840A (en) | 1992-06-11 | 1994-06-28 | Allergan, Inc. | Method of treatment with compounds having retinoid-like activity and reduced skin toxicity and lacking teratogenic effects |
JPH06135948A (ja) * | 1992-10-30 | 1994-05-17 | Taiho Yakuhin Kogyo Kk | スチレン誘導体又はその塩 |
JP2738486B2 (ja) * | 1992-11-20 | 1998-04-08 | ファイザー製薬株式会社 | 抗炎症剤としての新規なイソオキサゾリン類 |
US5973160A (en) * | 1992-12-23 | 1999-10-26 | Poss; Michael A. | Methods for the preparation of novel sidechain-bearing taxanes |
US5455265A (en) * | 1993-02-11 | 1995-10-03 | Allergan, Inc. | Method of treatment with compounds having selective agonist-like activity on RXR retinoid receptors |
US6172115B1 (en) | 1993-02-11 | 2001-01-09 | Allergan Sales, Inc. | Method for preventing onset of restenosis after angioplasty employing an RXR-specific retinoid |
EP0730587B1 (en) * | 1993-11-26 | 1999-12-08 | Pfizer Inc. | 3-phenyl-2-isoxazolines as antiinflammatory agents |
CA2184914C (en) * | 1994-03-09 | 2000-09-19 | Victoria L. Cohan | Isoxazoline compounds as 5-lipoxygenase inhibitors |
DE4408084A1 (de) * | 1994-03-10 | 1995-09-14 | Hoechst Ag | 3,5-Disubstituierte und 3,4,5-trisubstituierte 2-Isoxazoline und Isoxazole, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel |
US5510361A (en) * | 1994-10-20 | 1996-04-23 | The Procter & Gamble Company | Di-tert-butylphenol compounds with heterocyclic moiety, useful as anti-inflammatory agents |
CA2170661A1 (en) | 1995-03-22 | 1996-09-23 | John K. Thottathil | Novel methods for the preparation of taxanes using oaxzolidine intermediates |
US6011052A (en) * | 1996-04-30 | 2000-01-04 | Warner-Lambert Company | Pyrazolone derivatives as MCP-1 antagonists |
EP0966452B1 (de) * | 1997-01-17 | 2003-05-02 | Basf Aktiengesellschaft | Verfahren zur herstellung von schwefelhaltigen 2-chlor-3-(4,5-dihydroisoxazol-3-yl)-benzoesäuren |
EP1051165A2 (en) | 1998-01-26 | 2000-11-15 | Mitokor | Mitochondria protecting agents for treating mitochondria associated diseases |
AU2389100A (en) | 1998-12-23 | 2000-07-12 | Glaxo Group Limited | Assays for ligands for nuclear receptors |
JP4230770B2 (ja) * | 2001-01-18 | 2009-02-25 | ウェリケム バイオテック インコーポレーテッド | 免疫性疾患を治療するための新規な1,2−ジフェニルエテン誘導体 |
DE10121252A1 (de) * | 2001-04-30 | 2002-11-07 | Christos C Zouboulis | Behandlung der Akne |
WO2003105751A2 (en) * | 2002-06-17 | 2003-12-24 | Ho-Jeong Kwon | Novel curcumin derivatives |
FR2842806B1 (fr) * | 2002-07-26 | 2005-07-29 | Mayoly Spindler Lab | Nouveau procede de preparation de derives styryle pyrazoles, isoxazoles et isothiazoles |
AU2003275637A1 (en) * | 2002-10-24 | 2004-05-13 | Wakamoto Pharmaceutical Co., Ltd. | Pyrazole-4-alkanoate derivatives inhibiting cyclooxygenase and 5-lipoxygenase |
FR2846232B1 (fr) * | 2002-10-29 | 2004-12-10 | Oreal | Composition capillaire contenant un compose styryl-pyrazole, son utilisation pour stimuler ou induire la pousse des cheveux et/ou freiner leur chute |
WO2004039306A2 (fr) * | 2002-10-29 | 2004-05-13 | L'oreal | Composition capillaire contenant un compose styryl-pyrazole |
JP5063351B2 (ja) * | 2004-09-17 | 2012-10-31 | エグゼリクシス, インコーポレイテッド | ピラゾールキナーゼモジュレーターおよび使用方法 |
KR100604696B1 (ko) * | 2004-12-16 | 2006-07-31 | 연세대학교 산학협력단 | 신규한 커큐민 유도체 |
DE602006007355D1 (de) * | 2005-07-05 | 2009-07-30 | Symrise Gmbh & Co Kg | Hydroxyphenylalkadione und deren verwendung zur überdeckung von bitterem geschmack und/oder zur verstärkung von süssem geschmack |
WO2010045395A2 (en) * | 2008-10-14 | 2010-04-22 | Danyang Chen | Curcumin analog compositions and related methods |
NZ624963A (en) | 2009-04-29 | 2016-07-29 | Amarin Pharmaceuticals Ie Ltd | Pharmaceutical compositions comprising epa and a cardiovascular agent and methods of using the same |
RU2625790C2 (ru) | 2011-04-11 | 2017-07-19 | Грин Тек Ко.,Лтд. | Новое пиразольное производное |
CN104903297A (zh) * | 2012-10-10 | 2015-09-09 | 绿色科技株式会社 | 新型吡唑衍生物 |
JP6052673B2 (ja) * | 2013-04-25 | 2016-12-27 | 富士フイルム株式会社 | ピラゾール誘導体またはその塩ならびにそれらを含有する医薬組成物 |
CN104304244B (zh) * | 2014-09-11 | 2016-08-24 | 广西田园生化股份有限公司 | 一种用于农药制剂中的抗紫外线吸收剂 |
CN109563053B (zh) | 2016-06-28 | 2023-02-28 | 肯塔基大学研究基金会 | 前列腺素e合成酶抑制剂及使用其的方法 |
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US3687971A (en) * | 1970-06-22 | 1972-08-29 | Merck & Co Inc | 4-(pyrrolyl)-salicylic acid derivatives |
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US3948937A (en) * | 1972-02-29 | 1976-04-06 | E. I. Du Pont De Nemours And Company | Pyrazole plant growth regulants |
US3849436A (en) * | 1972-10-04 | 1974-11-19 | Du Pont | Cyclization of 2-(3-aryl-5-pyrazolyl)benzoic acids,esters and amides to 2-arylpyrazolo(5,1-a)isoindol-8-ones |
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SU792872A1 (ru) * | 1979-01-15 | 1981-09-07 | Ордена Трудового Красного Знамени Институт Органического Синтеза Ан Латсср | Способ получени 2-(изоксазолил-5)-бензойных кислот |
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US4346094A (en) * | 1980-09-22 | 1982-08-24 | Eli Lilly And Company | 3-Aryl-5-isothiazolecarboxylic acids and related compounds used to lower uric acid levels |
BE891489A (fr) * | 1980-12-16 | 1982-06-15 | Wellcome Found | Composes heterocycliques |
DE3148291A1 (de) * | 1981-12-05 | 1983-06-09 | Basf Ag, 6700 Ludwigshafen | Harnstoffderivate, verfahren zu ihrer herstellung und ihre verwendung zur bekaempfung unerwuenschten pflanzenwuchses |
JPS58177977A (ja) * | 1982-04-09 | 1983-10-18 | Grelan Pharmaceut Co Ltd | 4−フエニルピラゾ−ル類 |
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-
1987
- 1987-04-22 IE IE104187A patent/IE59813B1/en not_active IP Right Cessation
- 1987-04-24 AU AU71973/87A patent/AU613579B2/en not_active Ceased
- 1987-05-04 DK DK198702269A patent/DK175824B1/da not_active IP Right Cessation
- 1987-05-06 FI FI872015A patent/FI872015A/fi not_active Application Discontinuation
- 1987-05-08 PT PT84840A patent/PT84840B/pt unknown
- 1987-05-08 NZ NZ220248A patent/NZ220248A/xx unknown
- 1987-05-08 JP JP62110955A patent/JP2656035B2/ja not_active Expired - Fee Related
- 1987-05-08 NO NO871917A patent/NO871917L/no unknown
- 1987-05-09 KR KR870004564A patent/KR870011113A/ko not_active Application Discontinuation
- 1987-05-11 EP EP87106822A patent/EP0245825B1/en not_active Expired - Lifetime
- 1987-05-11 DE DE8787106822T patent/DE3768553D1/de not_active Expired - Fee Related
- 1987-05-11 AT AT87106822T patent/ATE61582T1/de not_active IP Right Cessation
- 1987-05-11 ES ES87106822T patent/ES2037681T3/es not_active Expired - Lifetime
-
1989
- 1989-08-16 US US07/395,165 patent/US5208251A/en not_active Expired - Lifetime
-
1991
- 1991-04-23 GR GR91400516T patent/GR3001831T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
PT84840B (pt) | 1990-02-08 |
JP2656035B2 (ja) | 1997-09-24 |
ATE61582T1 (de) | 1991-03-15 |
IE59813B1 (en) | 1994-04-06 |
DK226987A (da) | 1987-11-10 |
FI872015A0 (fi) | 1987-05-06 |
KR870011113A (ko) | 1987-12-21 |
EP0245825B1 (en) | 1991-03-13 |
DK175824B1 (da) | 2005-03-14 |
NO871917L (no) | 1987-11-10 |
JPS6322079A (ja) | 1988-01-29 |
DK226987D0 (da) | 1987-05-04 |
ES2037681T3 (es) | 1993-07-01 |
DE3768553D1 (de) | 1991-04-18 |
EP0245825A1 (en) | 1987-11-19 |
IE871041L (en) | 1987-11-09 |
NO871917D0 (no) | 1987-05-08 |
NZ220248A (en) | 1989-05-29 |
US5208251A (en) | 1993-05-04 |
PT84840A (en) | 1987-06-01 |
AU7197387A (en) | 1987-11-12 |
GR3001831T3 (en) | 1992-11-23 |
AU613579B2 (en) | 1991-08-08 |
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