FI870810A0 - Aminosyraderivater. - Google Patents
Aminosyraderivater.Info
- Publication number
- FI870810A0 FI870810A0 FI870810A FI870810A FI870810A0 FI 870810 A0 FI870810 A0 FI 870810A0 FI 870810 A FI870810 A FI 870810A FI 870810 A FI870810 A FI 870810A FI 870810 A0 FI870810 A0 FI 870810A0
- Authority
- FI
- Finland
- Prior art keywords
- aminosyraderivater
- carboxytetrahydropyrid
- carboxymethylpyrrolidin
- carboxypiperidin
- aminobut
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DK288385 | 1985-06-26 | ||
DK288385A DK288385D0 (da) | 1985-06-26 | 1985-06-26 | Aminosyrederivater |
DK8600076 | 1986-06-26 | ||
PCT/DK1986/000076 WO1987000171A1 (en) | 1985-06-26 | 1986-06-26 | Amino acid derivatives |
Publications (4)
Publication Number | Publication Date |
---|---|
FI870810A FI870810A (fi) | 1987-02-25 |
FI870810A0 true FI870810A0 (fi) | 1987-02-25 |
FI89355B FI89355B (fi) | 1993-06-15 |
FI89355C FI89355C (fi) | 1993-09-27 |
Family
ID=8116767
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FI870810A FI89355C (fi) | 1985-06-26 | 1987-02-25 | Foerfarande foer framstaellning av terapeutiskt aktiva 1-aminobut-3-en-foereningar |
Country Status (16)
Country | Link |
---|---|
US (1) | US5010090A (fi) |
EP (1) | EP0236342B1 (fi) |
JP (1) | JPH07103116B2 (fi) |
AT (1) | ATE67196T1 (fi) |
AU (1) | AU599326B2 (fi) |
CA (1) | CA1284503C (fi) |
DK (2) | DK288385D0 (fi) |
ES (1) | ES8800927A1 (fi) |
FI (1) | FI89355C (fi) |
GR (1) | GR861650B (fi) |
IE (1) | IE59084B1 (fi) |
LU (1) | LU90130I2 (fi) |
NZ (1) | NZ216657A (fi) |
PT (1) | PT82841B (fi) |
WO (1) | WO1987000171A1 (fi) |
ZA (1) | ZA864608B (fi) |
Families Citing this family (46)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DK704488D0 (da) * | 1988-12-19 | 1988-12-19 | Novo Industri As | Nye n-substituerede azaheterocykliske carboxylsyrer |
DK288385D0 (da) * | 1985-06-26 | 1985-06-26 | Novo Industri As | Aminosyrederivater |
DK588189D0 (da) * | 1989-11-22 | 1989-11-22 | Novo Nordisk As | Nye heterocykliske carboxylsyrer |
DK58291D0 (da) * | 1991-04-02 | 1991-04-02 | Novo Nordisk As | Krystalinsk stof og dets fremstilling |
TR199700873T1 (xx) * | 1995-02-28 | 1998-01-21 | H. Lund-Beck A/S | 4-Aminotetrahidrobenzizoksazol veya -izotiazol bile�ikleri. |
US5962449A (en) | 1995-04-07 | 1999-10-05 | Novo Nordisk A/S | Tricyclic compounds in treating hyperalgesic conditions and NIDDM |
JP3195360B2 (ja) * | 1995-05-05 | 2001-08-06 | ノボ ノルディスク アクティーゼルスカブ | チアガビン塩酸塩を含有する医薬組成物およびその製法 |
US6191165B1 (en) | 1996-05-31 | 2001-02-20 | Allelix Neuroscience Inc. | Pharmaceutical for treatment of neurological and neuropsychiatric disorders |
UA52661C2 (uk) * | 1996-06-14 | 2003-01-15 | Ново Нордіск А/С | Безводна кристалічна форма гідрохлориду r(-)-n-(4,4-ди(3-метилтієн-2-іл)бут-3-еніл) ніпекотинової кислоти |
US5958951A (en) * | 1996-06-14 | 1999-09-28 | Novo Nordiskials | Modified form of the R(-)-N-(4,4-di(3-methylthien-2-yl)but-3-enyl)-nipecotic acid hydrochloride |
US5914333A (en) * | 1996-07-31 | 1999-06-22 | Novo Nordisk A/S | Treatment of psychotic disorders |
EP0991409B1 (en) * | 1997-08-01 | 2002-01-30 | ELAN CORPORATION, Plc | Controlled release pharmaceutical compositions containing tiagabine |
IE970588A1 (en) | 1997-08-01 | 2000-08-23 | Elan Corp Plc | Controlled release pharmaceutical compositions containing tiagabine |
US6503926B2 (en) * | 1998-09-04 | 2003-01-07 | Millennium Pharmaceuticals, Inc. | Chemokine receptor antagonists and methods of use therefor |
US6288083B1 (en) * | 1998-09-04 | 2001-09-11 | Millennium Pharmaceuticals, Inc. | Chemokine receptor antagonists and methods of use therefor |
DE19840611A1 (de) * | 1998-09-05 | 2000-03-09 | Klaus Wanner | GABA-uptake-Inhibitoren mit Pyrrolidinstruktur |
CA2361924A1 (en) * | 1999-01-12 | 2000-07-20 | Izumi Kamo | Compositions for treating frequent urination and urinary incontinence |
US6872734B2 (en) | 2000-10-20 | 2005-03-29 | Abbott Laboratories | Use of tiagabine for treatment of diabetic neuropathy and migraine |
IL155704A0 (en) | 2000-11-30 | 2003-11-23 | Pfizer Prod Inc | Combination of gaba agonists and sorbitol dehydrogenase inhibitors |
IL155710A0 (en) * | 2000-11-30 | 2003-11-23 | Pfizer Prod Inc | Combination of gaba agonists and aldose reductase inhibitors |
WO2002066456A2 (en) | 2001-02-16 | 2002-08-29 | Allelix Neuroscience, Inc. | Thiophene substituted amine derivatives as glyt-1 inhibitors |
EP2266590A3 (en) | 2002-02-22 | 2011-04-20 | Shire LLC | Active agent delivery sytems and methods for protecting and administering active agents |
CN1382441A (zh) * | 2002-05-21 | 2002-12-04 | 中国科学院上海生命科学研究院 | γ-氨基丁酸转运蛋白抑制剂在制备镇痛药物中的应用 |
RU2005135454A (ru) * | 2003-05-16 | 2006-06-27 | Пфайзер Продактс Инк. (Us) | Терапевтические комбинации атипичных нейролептиков с модуляторами гамк и/или противосудорожными препаратами |
ES2515092T3 (es) | 2003-12-11 | 2014-10-29 | Sunovion Pharmaceuticals Inc. | Combinación de un sedante y un modulador neurotransmisor y métodos de mejorar la calidad del sueño y de tratar la depresión |
US7667042B2 (en) * | 2003-12-24 | 2010-02-23 | Sun Pharma Advanced Research Company Ltd. | Stable polymorphic forms of an anticonvulsant |
CN1314684C (zh) * | 2003-12-24 | 2007-05-09 | 中国科学院上海有机化学研究所 | 噻加宾及其消旋体和s-构型的合成方法及其无定形粉末的制法 |
WO2005082372A1 (en) * | 2004-01-29 | 2005-09-09 | Pfizer Products Inc. | COMBINATION OF γ-AMINOBUTYRIC ACID MODULATORS AND 5-HT 1B RECEPTOR ANTAGONISTS |
WO2005092886A1 (en) * | 2004-03-29 | 2005-10-06 | Ranbaxy Laboratories Limited | Process for the preparation of amorphous form of tiagabine |
WO2006013550A2 (en) * | 2004-08-04 | 2006-02-09 | Ranbaxy Laboratories Limited | Process for preparation of piperidine carboxylic acid |
EP2258359A3 (en) | 2005-08-26 | 2011-04-06 | Braincells, Inc. | Neurogenesis by muscarinic receptor modulation with sabcomelin |
JP2009506069A (ja) | 2005-08-26 | 2009-02-12 | ブレインセルス,インコーポレイティド | ムスカリン性受容体調節による神経発生 |
AU2006304787A1 (en) | 2005-10-21 | 2007-04-26 | Braincells, Inc. | Modulation of neurogenesis by PDE inhibition |
CA2625210A1 (en) * | 2005-10-31 | 2007-05-10 | Braincells, Inc. | Gaba receptor mediated modulation of neurogenesis |
US20100216734A1 (en) | 2006-03-08 | 2010-08-26 | Braincells, Inc. | Modulation of neurogenesis by nootropic agents |
EP2377531A2 (en) | 2006-05-09 | 2011-10-19 | Braincells, Inc. | Neurogenesis by modulating angiotensin |
EP2026813A2 (en) | 2006-05-09 | 2009-02-25 | Braincells, Inc. | 5 ht receptor mediated neurogenesis |
US20080051435A1 (en) * | 2006-08-18 | 2008-02-28 | Cephalon, Inc. | Crystalline and amorphous forms of tiagabine |
US20080064727A1 (en) * | 2006-08-18 | 2008-03-13 | Cephalon, Inc. | Crystalline forms of tiagabine hydrochloride |
US7998971B2 (en) | 2006-09-08 | 2011-08-16 | Braincells Inc. | Combinations containing a 4-acylaminopyridine derivative |
US20100184806A1 (en) | 2006-09-19 | 2010-07-22 | Braincells, Inc. | Modulation of neurogenesis by ppar agents |
US20090082401A1 (en) * | 2007-09-25 | 2009-03-26 | Protia, Llc | Deuterium-enriched tiagabine |
US20100216805A1 (en) | 2009-02-25 | 2010-08-26 | Braincells, Inc. | Modulation of neurogenesis using d-cycloserine combinations |
CN101857591B (zh) * | 2009-04-09 | 2013-06-05 | 北京京卫燕康药物研究所有限公司 | 盐酸噻加宾晶型及其制备方法 |
CN102070624B (zh) * | 2011-01-25 | 2013-04-10 | 赵学清 | 一种盐酸噻加宾的合成方法及无水盐酸噻加宾的制备方法 |
CN102827152B (zh) * | 2012-09-17 | 2014-11-05 | 扬子江药业集团四川海蓉药业有限公司 | 噻加宾的制备方法及其前体化合物 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4383999A (en) * | 1981-05-26 | 1983-05-17 | Smithkline Beckman Corporation | Inhibition of GABA uptake by N-substituted azaheterocyclic carboxylic acids and their esters |
US4514414A (en) * | 1982-10-25 | 1985-04-30 | Smithkline Beckman Corporation | N-Substituted pyrrolidineacetic acids and their esters |
DK288385D0 (da) * | 1985-06-26 | 1985-06-26 | Novo Industri As | Aminosyrederivater |
EP0231996B1 (en) * | 1986-01-07 | 1993-10-06 | Novo Nordisk A/S | Novel amino acid derivatives |
-
1985
- 1985-06-26 DK DK288385A patent/DK288385D0/da not_active Application Discontinuation
-
1986
- 1986-06-20 ZA ZA864608A patent/ZA864608B/xx unknown
- 1986-06-24 CA CA000512333A patent/CA1284503C/en not_active Expired - Lifetime
- 1986-06-25 IE IE170286A patent/IE59084B1/en not_active IP Right Cessation
- 1986-06-25 ES ES556659A patent/ES8800927A1/es not_active Expired
- 1986-06-25 GR GR861650A patent/GR861650B/el unknown
- 1986-06-25 NZ NZ216657A patent/NZ216657A/xx unknown
- 1986-06-25 PT PT82841A patent/PT82841B/pt unknown
- 1986-06-26 AU AU61336/86A patent/AU599326B2/en not_active Expired
- 1986-06-26 JP JP61503845A patent/JPH07103116B2/ja not_active Expired - Lifetime
- 1986-06-26 WO PCT/DK1986/000076 patent/WO1987000171A1/en active IP Right Grant
- 1986-06-26 EP EP86904114A patent/EP0236342B1/en not_active Expired - Lifetime
- 1986-06-26 AT AT86904114T patent/ATE67196T1/de active
-
1987
- 1987-02-25 FI FI870810A patent/FI89355C/fi not_active IP Right Cessation
- 1987-02-26 DK DK100887A patent/DK156398C/da not_active IP Right Cessation
-
1988
- 1988-10-07 US US07/254,557 patent/US5010090A/en not_active Expired - Lifetime
-
1997
- 1997-08-29 LU LU90130C patent/LU90130I2/fr unknown
Also Published As
Publication number | Publication date |
---|---|
LU90130I2 (fr) | 1997-10-24 |
AU599326B2 (en) | 1990-07-19 |
WO1987000171A1 (en) | 1987-01-15 |
DK100887A (da) | 1987-02-26 |
DK100887D0 (da) | 1987-02-26 |
FI89355B (fi) | 1993-06-15 |
FI870810A (fi) | 1987-02-25 |
AU6133686A (en) | 1987-01-30 |
FI89355C (fi) | 1993-09-27 |
ES8800927A1 (es) | 1987-12-01 |
US5010090A (en) | 1991-04-23 |
IE59084B1 (en) | 1994-01-12 |
JPH07103116B2 (ja) | 1995-11-08 |
GR861650B (en) | 1986-10-30 |
ZA864608B (en) | 1987-02-25 |
PT82841A (en) | 1986-07-01 |
EP0236342A1 (en) | 1987-09-16 |
JPS62503172A (ja) | 1987-12-17 |
DK156398C (da) | 1990-01-08 |
CA1284503C (en) | 1991-05-28 |
IE861702L (en) | 1986-12-26 |
NZ216657A (en) | 1989-10-27 |
EP0236342B1 (en) | 1991-09-11 |
ES556659A0 (es) | 1987-12-01 |
PT82841B (pt) | 1989-01-17 |
DK156398B (da) | 1989-08-14 |
DK288385D0 (da) | 1985-06-26 |
ATE67196T1 (de) | 1991-09-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
BB | Publication of examined application | ||
NF | Re-establishment of lapsed right | ||
SPCG | Supplementary protection certificate granted |
Spc suppl protection certif: L112 Extension date: 20110613 |
|
FG | Patent granted |
Owner name: NOVO NORDISK A/S |
|
MA | Patent expired |