FI851143L - 1-alkylsubstituerade 1,4-dihydropyridinlaktoner, foerfarande foer deras framstaellning och deras anvaendning som laekemedel. - Google Patents

1-alkylsubstituerade 1,4-dihydropyridinlaktoner, foerfarande foer deras framstaellning och deras anvaendning som laekemedel.

Info

Publication number
FI851143L
FI851143L FI851143A FI851143A FI851143L FI 851143 L FI851143 L FI 851143L FI 851143 A FI851143 A FI 851143A FI 851143 A FI851143 A FI 851143A FI 851143 L FI851143 L FI 851143L
Authority
FI
Finland
Prior art keywords
alkyl
atoms
chain
optionally
deras
Prior art date
Application number
FI851143A
Other languages
English (en)
Other versions
FI83651B (fi
FI83651C (fi
FI851143A0 (fi
Inventor
Siegfried Goldmann
Friedrich Bossert
Hilmar Bischoff
Dieter Petzinna
Walter Puls
Klaus Schlossmann
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of FI851143A0 publication Critical patent/FI851143A0/fi
Publication of FI851143L publication Critical patent/FI851143L/fi
Publication of FI83651B publication Critical patent/FI83651B/fi
Application granted granted Critical
Publication of FI83651C publication Critical patent/FI83651C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
    • C07D491/16—Peri-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
FI851143A 1984-03-23 1985-03-21 Foerfarande foer framstaellning av nya terapeutiskt anvaendbara 1,4-dihydropyridinlaktoner. FI83651C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3410645 1984-03-23
DE19843410645 DE3410645A1 (de) 1984-03-23 1984-03-23 L-alkylsubstituierte 1,4-dihydropyridinlactone, verfahren zu ihrer herstellung und ihre verwendung in arzneimitteln

Publications (4)

Publication Number Publication Date
FI851143A0 FI851143A0 (fi) 1985-03-21
FI851143L true FI851143L (fi) 1985-09-24
FI83651B FI83651B (fi) 1991-04-30
FI83651C FI83651C (fi) 1991-08-12

Family

ID=6231357

Family Applications (1)

Application Number Title Priority Date Filing Date
FI851143A FI83651C (fi) 1984-03-23 1985-03-21 Foerfarande foer framstaellning av nya terapeutiskt anvaendbara 1,4-dihydropyridinlaktoner.

Country Status (24)

Country Link
US (1) US5026714A (fi)
EP (1) EP0158138B1 (fi)
JP (1) JPS60209584A (fi)
KR (1) KR850006439A (fi)
AT (1) ATE37880T1 (fi)
AU (1) AU569783B2 (fi)
CA (1) CA1249270A (fi)
CS (1) CS250681B2 (fi)
DD (1) DD234424A5 (fi)
DE (2) DE3410645A1 (fi)
DK (1) DK158517C (fi)
EG (1) EG16785A (fi)
ES (9) ES8607309A1 (fi)
FI (1) FI83651C (fi)
GR (1) GR850719B (fi)
HU (1) HU191167B (fi)
IL (1) IL74659A (fi)
NO (1) NO161259C (fi)
NZ (1) NZ211512A (fi)
PH (3) PH23826A (fi)
PL (1) PL143884B1 (fi)
PT (1) PT80146B (fi)
SU (1) SU1319785A3 (fi)
ZA (1) ZA852172B (fi)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3521761A1 (de) * 1985-06-19 1987-01-02 Bayer Ag Neue 1,4-dihydropyridine, verfahren zur herstellung und ihre verwendung in arzneimitteln
US5162338A (en) * 1986-01-11 1992-11-10 Bayer Aktiengesellschaft Circulation active 4-aminoaryldihydropryidine lactones
DE3600596A1 (de) * 1986-01-11 1987-07-16 Bayer Ag 4-aminoaryldihydropyridinlactone, verfahren zu ihrer herstellung und ihre verwendung in arzneimitteln
DE3629545A1 (de) * 1986-08-30 1988-03-10 Bayer Ag Dihydropyridinverbindungen, verfahren zu ihrer herstellung und ihre verwendung
DE3706204A1 (de) * 1987-02-26 1988-09-08 Bayer Ag Benzylaminoaryl-dihydropyridinlactone, verfahren zu ihrer herstellung und ihre verwendung in arzneimitteln
GB8716971D0 (en) * 1987-07-17 1987-08-26 Pfizer Ltd Therapeutic agents
DE4430092A1 (de) * 1994-08-25 1996-02-29 Bayer Ag 2,3-Cyclisch kondensierte 1,4-Dihydropyridine, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
TW200519091A (en) * 2003-09-10 2005-06-16 Synta Pharmaceuticals Corp Dihydropyridine compounds for treating or preventing metabolic disorders
WO2021253180A1 (en) * 2020-06-15 2021-12-23 Novartis Ag Methyl (r) -2- (fluoromethyl) -5-oxo-4-phenyl-4, 5, 6, 7-tetrahydro-1h-cyclopenta [b] pyridine-3-carboxylate and methyl (r) -2- (fluoromethyl) -5-oxo-4-phenyl-1, 4, 5, 7-tetrahydrofuro [3, 4-b] pyridine-3-carboxylate as cav1.2 activators
KR20230022979A (ko) 2020-06-16 2023-02-16 노파르티스 아게 CAV1.2 활성제로서의 메틸 2-메틸-5-옥소-1,4,5,7-테트라하이드로푸로[3,4-b]피리딘-3-카르복실레이트 화합물

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2005116C3 (de) * 1970-02-05 1980-02-14 Bayer Ag, 5090 Leverkusen Symmetrische 1,4-Dihydropyridin-3,5-dicarbonsäureester
GB1552911A (en) * 1975-07-02 1979-09-19 Fujisawa Pharmaceutical Co 1,4 dihydropyridine derivatives and the preparation thereof
US4284634A (en) * 1975-07-02 1981-08-18 Fujisawa Pharmaceutical Co., Ltd. 1,4-Dihydropyridine derivatives, and pharmaceutical method of the same
US4253248A (en) 1979-04-16 1981-03-03 Cornish Judson E Teaching machine apparatus
DE3206671A1 (de) * 1982-02-25 1983-09-01 Bayer Ag, 5090 Leverkusen Dihydropyridine mit positiv inotroper wirkung, neue verbindungen, ihre verwendung in arzneimitteln und verfahren zu ihrer herstellung
NZ201395A (en) * 1981-07-30 1987-02-20 Bayer Ag Pharmaceutical compositions containing 1,4-dihydropyridines and certain of these dihydropyridines
DE3130041A1 (de) * 1981-07-30 1983-02-17 Bayer Ag, 5090 Leverkusen Dihydropyridine mit positiv inotroper wirkung, neue verbindungen, ihre verwendung in arzneimitteln und verfahren zu ihrer herstellung
US4497808A (en) * 1981-12-30 1985-02-05 Ciba-Geigy Corporation N-Oxide compounds useful in the treatment of cardiovascular ailments
DE3209274A1 (de) * 1982-03-13 1983-09-15 Bayer Ag, 5090 Leverkusen Pyridincarbonsaeureester, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
DE3209276A1 (de) * 1982-03-13 1983-09-15 Bayer Ag, 5090 Leverkusen Arzneimittel mit antihypoxischer und ischaemie-protektiver wirkung
EP0111455A3 (de) * 1982-12-10 1984-07-25 Ciba-Geigy Ag Ungesättigte Lactone
DE3521761A1 (de) * 1985-06-19 1987-01-02 Bayer Ag Neue 1,4-dihydropyridine, verfahren zur herstellung und ihre verwendung in arzneimitteln
DE3601226A1 (de) * 1986-01-17 1987-07-23 Bayer Ag Dihydropyridinlactole, verfahren zur herstellung und ihre verwendung in arzneimitteln

Also Published As

Publication number Publication date
FI83651B (fi) 1991-04-30
ES551544A0 (es) 1987-01-01
ES8702417A1 (es) 1986-12-16
PH23455A (en) 1989-08-07
IL74659A0 (en) 1985-06-30
DK158517B (da) 1990-05-28
EP0158138A1 (de) 1985-10-16
ES8702416A1 (es) 1987-01-01
ES551542A0 (es) 1986-12-16
ES541309A0 (es) 1986-06-16
SU1319785A3 (ru) 1987-06-23
ES8702413A1 (es) 1987-01-01
EG16785A (en) 1990-10-30
IL74659A (en) 1988-11-30
DE3565541D1 (en) 1988-11-17
DE3410645A1 (de) 1985-09-26
ES551547A0 (es) 1987-03-16
DK131685A (da) 1985-09-24
FI83651C (fi) 1991-08-12
ES8702414A1 (es) 1986-12-16
NZ211512A (en) 1988-07-28
EP0158138B1 (de) 1988-10-12
GR850719B (fi) 1985-07-19
PT80146B (en) 1987-03-23
ES551541A0 (es) 1987-01-01
ZA852172B (en) 1985-12-24
NO161259B (no) 1989-04-17
NO850891L (no) 1985-09-24
JPS60209584A (ja) 1985-10-22
ATE37880T1 (de) 1988-10-15
DD234424A5 (de) 1986-04-02
ES551545A0 (es) 1986-12-16
ES8702415A1 (es) 1986-12-16
PH23826A (en) 1989-11-23
ES8704173A1 (es) 1987-03-16
ES8702418A1 (es) 1986-12-16
ES551543A0 (es) 1986-12-16
DK131685D0 (da) 1985-03-22
FI851143A0 (fi) 1985-03-21
HUT37795A (en) 1986-02-28
ES551546A0 (es) 1987-03-16
ES551548A0 (es) 1986-12-16
ES8704174A1 (es) 1987-03-16
HU191167B (en) 1987-01-28
US5026714A (en) 1991-06-25
CA1249270A (en) 1989-01-24
AU4044985A (en) 1985-09-26
AU569783B2 (en) 1988-02-18
PH24347A (en) 1990-06-13
ES8607309A1 (es) 1986-06-16
CS250681B2 (en) 1987-05-14
PT80146A (en) 1985-04-01
PL252522A1 (en) 1986-04-08
NO161259C (no) 1989-07-26
DK158517C (da) 1990-11-05
PL143884B1 (en) 1988-03-31
KR850006439A (ko) 1985-10-05

Similar Documents

Publication Publication Date Title
FI851143A0 (fi) 1-alkylsubstituerade 1,4-dihydropyridinlaktoner, foerfarande foer deras framstaellning och deras anvaendning som laekemedel.
ES469892A1 (es) Procedimiento para realizar reacciones fotoquimicas para la obtencion de polimeros organicos
FI860107A (fi) Aminofenolderivat.
SE8106441L (sv) 2,6-c-dimetyltyrosin?721-d-aminosyra?722-omega-aminokapronsyra-och-gamma-aminosmorsyraderivat av metioninencefalin
BR0207829A (pt) Composto de carbamato para uso na prevenção ou tratamento de distúrbios psicóticos
ES2086165T3 (es) Procedimiento para la preparacion de olefinas sustituidas con grupos aromaticos a partir de compuestos cloro-aromaticos.
AR005545A1 (es) Un procedimiento para la preparacion de derivados de imidazodiacepina.
PE20030362A1 (es) Sistemas de indan-1-ol-sustituidos en c2 y procedimiento para su preparacion

Legal Events

Date Code Title Description
MM Patent lapsed
MM Patent lapsed

Owner name: BAYER AKTIENGESELLSCHAFT