FI820839L - Nya 3,4-dihydro-5h-2,3-benzodiazepinderivat och foerfarande for deras framstaellning - Google Patents

Nya 3,4-dihydro-5h-2,3-benzodiazepinderivat och foerfarande for deras framstaellning

Info

Publication number
FI820839L
FI820839L FI820839A FI820839A FI820839L FI 820839 L FI820839 L FI 820839L FI 820839 A FI820839 A FI 820839A FI 820839 A FI820839 A FI 820839A FI 820839 L FI820839 L FI 820839L
Authority
FI
Finland
Prior art keywords
benzodiazepinderivat
nya
dihydro
och foerfarande
deras framstaellning
Prior art date
Application number
FI820839A
Other languages
English (en)
Finnish (fi)
Inventor
Jeno Koeroesi
Tibor Lang
Ferenc Andrasi
Jozsef Szekely
Tamas Hamori
Tibor Balogh
Lajos Ila
Horvath Katalin Goldschmidt
Eleonora Sineger
Imro Moravcsik
Original Assignee
Egyt Gyogyszervegyeszeti Gyar
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Egyt Gyogyszervegyeszeti Gyar filed Critical Egyt Gyogyszervegyeszeti Gyar
Publication of FI820839L publication Critical patent/FI820839L/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/02—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
FI820839A 1981-03-12 1982-03-11 Nya 3,4-dihydro-5h-2,3-benzodiazepinderivat och foerfarande for deras framstaellning FI820839L (fi)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU81620A HU186760B (en) 1981-03-12 1981-03-12 Process for preparing 3,4-dihydro-5h-2,3-aenzodiazepine derivatives

Publications (1)

Publication Number Publication Date
FI820839L true FI820839L (fi) 1982-09-13

Family

ID=10950496

Family Applications (1)

Application Number Title Priority Date Filing Date
FI820839A FI820839L (fi) 1981-03-12 1982-03-11 Nya 3,4-dihydro-5h-2,3-benzodiazepinderivat och foerfarande for deras framstaellning

Country Status (23)

Country Link
US (1) US4423044A (de)
JP (1) JPS57159772A (de)
AT (1) AT383120B (de)
AU (1) AU550388B2 (de)
BE (1) BE892395A (de)
CA (1) CA1178584A (de)
CH (1) CH648553A5 (de)
CS (1) CS224646B2 (de)
DD (1) DD204698A5 (de)
DE (1) DE3209100A1 (de)
DK (1) DK106882A (de)
ES (1) ES510348A0 (de)
FI (1) FI820839L (de)
FR (1) FR2501686A1 (de)
GB (1) GB2097387B (de)
GR (1) GR76111B (de)
HU (1) HU186760B (de)
IL (1) IL65076A (de)
IT (1) IT1190732B (de)
NL (1) NL8201005A (de)
NO (1) NO820798L (de)
SE (1) SE8201537L (de)
SU (1) SU1151206A3 (de)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3971179A (en) * 1969-08-13 1976-07-27 Andrew Bodocsi Non-bonded framing system
DE3124013A1 (de) * 1981-06-19 1982-12-30 Kali-Chemie Pharma Gmbh, 3000 Hannover 2-acylaminomethyl-1,4-benzodiazepin-verbindungen sowie verfahren und zwischenprodukte zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
HU191698B (en) * 1984-07-27 1987-03-30 Gyogyszerkutato Intezet Process for producing new 1-aryl-5h-2beta-benzodiazepines
US5204339A (en) * 1986-01-31 1993-04-20 Whitby Research, Inc. Penetration enhancers for transdermal delivery of systemic agents
HU198494B (en) * 1986-08-15 1989-10-30 Gyogyszerkutato Intezet Process for producing new 3,4-dihydro-5h-2,3-benzodiazepine derivative and acid addition salts thereof, as well as pharmaceutical compositions comprising same
EP0322582A3 (de) * 1987-12-07 1989-09-13 Hoechst-Roussel Pharmaceuticals Incorporated 4-Heteroaryl-1,3-benzodiazepine und 2-substituierte Alpha-(heteroaryl) benzenethanamine, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
HU206719B (en) * 1990-12-21 1992-12-28 Gyogyszerkutato Intezet Process for producing 1-/4-acylamino-phenyl/-7,8-methylenedioxy-5h-2,3-benzodiazepine derivatives, acid addicional salts and pharmaceutical compositions containing them
SK283859B6 (sk) * 1995-02-09 2004-03-02 EGIS Gyógyszergyár Rt. 1-[2'-(Substituovaný)vinyl]-5H-2,3-benzodiazepínové deriváty, spôsob ich prípravy a medziprodukty na ich prípravu, liečivá ich obsahujúce a ich použitie
EP0726257B1 (de) * 1995-02-09 2001-04-11 Egis Gyogyszergyar Rt. 1-(Hetero)Arylvinyl-5H-2,3-benzodiazepinderivative verwendbar zur Behandlung von Erkrankungen des Zentralnervensystems, sowie Benzopyrylium Intermediate zu ihrer Herstellung
HU224435B1 (hu) * 1995-02-09 2005-10-28 EGIS Gyógyszergyár Rt. Benzodiazepin-származékok, eljárás előállításukra, alkalmazásukra és ezeket tartalmazó gyógyászati készítmények
DE19604920A1 (de) 1996-02-01 1997-08-07 Schering Ag Neue 2,3-Benzodiazepinderivate, deren Herstellung und Verwendung als Arzneimittel
ES2111493B1 (es) * 1996-02-08 1999-08-01 Egyt Gyogyszervegyeszeti Gyar Derivados de 1-(2- (vinilo substituido ) ) -5h-2,3-benzo-diazepina, procedimiento para su preparacion, composiciones farmaceuticas que los contienen y utilizaciones correspondientes.
ZA972746B (en) * 1996-04-04 1998-10-09 Egyt Gyogyszervegyeszeti Gyar Novel 2,3-benzodiazepine derivatives
US6080736A (en) * 1999-10-27 2000-06-27 Janus Pharmaceuticals, Inc. Methods and compositions for treating and preventing anxiety and anxiety disorders using optically pure (R) tofisopam
US6649607B2 (en) 2001-05-18 2003-11-18 Vela Pharmaceuticals, Inc. Compositions and methods for treating or preventing convulsions or seizures
JP2006514084A (ja) * 2002-12-03 2006-04-27 ヴェラ ファーマスーティカルズ インコーポレイテッド １−（３−ヒドロキシ−４−メトキシフェニル）−４−メチル−５−エチル−７，８−ジメトキシ−５ｈ−２，３−ベンゾジアゼピンの製薬組成物及びその用途
AU2003293405A1 (en) * 2002-12-03 2004-06-23 Vela Pharmaceuticals, Inc. Pharmaceutical composition of 1-(3,4-dimethoxyphenyl)-4-methyl-5-ethyl-7-methoxy-8-hydroxy-5h-2,3-benzodiazepine and uses thereof
US6638928B1 (en) 2002-12-03 2003-10-28 Vela Pharmaceuticals, Inc. Treatment of irritable bowel syndrome and nonulcer dyspepsia with substituted 2,3-benzodiazepines
US6864251B2 (en) * 2002-12-03 2005-03-08 Vela Pharmaceuticals, Inc. Treatment of LTB4-mediated inflammatory disorders with optically-pure (R)-2,3-benzodiazepines
US7022700B2 (en) * 2002-12-03 2006-04-04 Vela Pharmaceuticals, Inc. Method of increasing neutrophil production using optically-pure (R)-2,3-benzodiazepines
US20040162284A1 (en) * 2003-02-19 2004-08-19 Harris Herbert W. Method of lowering body temperature with (S) tofisopam
US20040224943A1 (en) * 2003-02-19 2004-11-11 Leventer Steven M. Method of lowering body temperature with (R) - 2,3-benzodiazepines
US20070021412A1 (en) * 2003-05-16 2007-01-25 Vela Pharmaceuticals, Inc. Treatment of gastrointestinal dysfunction and related stress with an enantiomerically-pure (S) 2,3-benzodiazepine
CA2525273C (en) * 2003-05-16 2012-04-17 Vela Pharmaceuticals, Inc. Treatment of gastrointestinal dysfunction and related stress with an enantiomerically-pure (r) 2,3-benzodiazepine
US20040254173A1 (en) * 2003-06-13 2004-12-16 Leventer Steven M. Modulation of dopamine responses with substituted (S)-2,3-benzodiazepines
US7541355B2 (en) * 2005-05-23 2009-06-02 Vela Acquisition Corporation Conversion process for 2,3-benzodiazepine enantiomers
TW200902024A (en) * 2007-04-02 2009-01-16 Teva Pharma Novel 2,3-benzodiazepine derivatives and their use as antipsychotic agents

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK118660B (da) * 1966-12-09 1970-09-21 Egyt Gyogyszervegyeszeti Gyar Analogifremgangsmåde til fremstilling af 1-(3',4'-dimethoxyphenyl)-3-methyl-4-ethyl-6,7-dimethoxy-isoquinolin-N-imid.
USRE30014E (en) 1966-12-09 1979-05-29 Egyesult Gyogyazer-es Tapozergyar 1-(3,4-Dimethoxy-phenyl)-4-methyl-5-ethyl-7,8-dimethoxy-5H-2,3-benzodiazepine
HU179018B (en) * 1978-10-19 1982-08-28 Gyogyszerkutato Intezet Process for producing new 5h-2,3-benzodiazepine derivatives

Also Published As

Publication number Publication date
ES8302671A1 (es) 1983-02-01
CS224646B2 (en) 1984-01-16
DE3209100A1 (de) 1982-10-28
CA1178584A (en) 1984-11-27
SE8201537L (sv) 1982-09-13
GB2097387B (en) 1984-09-19
CH648553A5 (de) 1985-03-29
JPS57159772A (en) 1982-10-01
NO820798L (no) 1982-09-13
NL8201005A (nl) 1982-10-01
HU186760B (en) 1985-09-30
AT383120B (de) 1987-05-25
IL65076A (en) 1984-12-31
IT8220094A0 (it) 1982-03-11
IT1190732B (it) 1988-02-24
ES510348A0 (es) 1983-02-01
DK106882A (da) 1982-09-13
US4423044A (en) 1983-12-27
ATA96982A (de) 1986-10-15
FR2501686B1 (de) 1985-03-01
AU550388B2 (en) 1986-03-20
DD204698A5 (de) 1983-12-07
GR76111B (de) 1984-08-03
SU1151206A3 (ru) 1985-04-15
GB2097387A (en) 1982-11-03
FR2501686A1 (fr) 1982-09-17
AU8130882A (en) 1982-09-16
BE892395A (fr) 1982-09-08

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Legal Events

Date Code Title Description
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Owner name: EGYT GYOGYSZERVEGYESZETI GYAR