FI80213B - Modifiering av kirurgiska strukturelement innehaollande polyglykol foer erhaollande av olika fysikaliska egenskaper in vivo. - Google Patents

Modifiering av kirurgiska strukturelement innehaollande polyglykol foer erhaollande av olika fysikaliska egenskaper in vivo. Download PDF

Info

Publication number
FI80213B
FI80213B FI842435A FI842435A FI80213B FI 80213 B FI80213 B FI 80213B FI 842435 A FI842435 A FI 842435A FI 842435 A FI842435 A FI 842435A FI 80213 B FI80213 B FI 80213B
Authority
FI
Finland
Prior art keywords
vivo
surgical
modifying
strength
component according
Prior art date
Application number
FI842435A
Other languages
English (en)
Finnish (fi)
Other versions
FI80213C (sv
FI842435A0 (fi
FI842435A (fi
Inventor
Thomas Alexander Ritter
Alan Lawrence Kaganov
John Peter Budris
Original Assignee
American Cyanamid Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Cyanamid Co filed Critical American Cyanamid Co
Publication of FI842435A0 publication Critical patent/FI842435A0/fi
Publication of FI842435A publication Critical patent/FI842435A/fi
Application granted granted Critical
Publication of FI80213B publication Critical patent/FI80213B/fi
Publication of FI80213C publication Critical patent/FI80213C/sv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G59/00—Polycondensates containing more than one epoxy group per molecule; Macromolecules obtained by polymerising compounds containing more than one epoxy group per molecule using curing agents or catalysts which react with the epoxy groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/18—Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/02—Inorganic materials
    • A61L27/04—Metals or alloys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/40—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A61L27/44—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix
    • A61L27/46—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix with phosphorus-containing inorganic fillers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/04—Macromolecular materials
    • A61L31/06—Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/12—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A61L31/125—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08K—Use of inorganic or non-macromolecular organic substances as compounding ingredients
    • C08K3/00—Use of inorganic substances as compounding ingredients
    • C08K3/01—Use of inorganic substances as compounding ingredients characterized by their specific function
    • C08K3/013—Fillers, pigments or reinforcing additives
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L67/00—Compositions of polyesters obtained by reactions forming a carboxylic ester link in the main chain; Compositions of derivatives of such polymers
    • C08L67/04—Polyesters derived from hydroxycarboxylic acids, e.g. lactones
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S522/00—Synthetic resins or natural rubbers -- part of the class 520 series
    • Y10S522/911—Specified treatment involving megarad or less

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Polymers & Plastics (AREA)
  • Transplantation (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Organic Chemistry (AREA)
  • Dermatology (AREA)
  • Materials Engineering (AREA)
  • Inorganic Chemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Surgery (AREA)
  • Vascular Medicine (AREA)
  • Composite Materials (AREA)
  • Engineering & Computer Science (AREA)
  • Materials For Medical Uses (AREA)

Claims (8)

1. Förfarande för modifiering av ett kirurgiskt strukturelement, vilket framställts av en bioabsorberbar 5 polymer med en glykolesterbindning, sä att man pä ett kontrollerbart sätt päverkar bibehällandet av dess egen-skaper in vivo, kännetecknat därav, att ele-mentet underkastas en besträlningsbehandling i en sädan dos ooh under en tid, som är tillräcklig att pä ett kon- 10 trollerbart sätt minska tiden, som behövs för elementet att undergä sönderfall in vivo i fragment, vilka kan av-lägsnas frän eller transporteras bort frän kroppen utan absorption.
2. Förfarande för modifiering av ett kirurgiskt 15 strukturelement enligt patentkravet 1, kännetecknat därav, att besträlningsdosen är större än den som behövs för sterilisering.
3. Förfarande för modifiering av ett kirurgiskt strukturelement enligt patentkravet 1, känneteck- 20. a t därav, att besträlningsdosen överstiger 2,5 Mrad.
4. Förfarande för modifiering av ett kirurgiskt strukturelement enligt patentkravet 1, kännetecknat därav, att besträlningsdosen är 2,5 - 10 Mrad.
5. Förfarande för modifiering av ett kirurgiskt 25 strukturelement enligt patentkravet 1, kännetecknat därav, att sönderdelningen i fragment in vivo äs-tadkoms genom förlust av hällfastheten in vivo hos struk-turelementet, vilken förlust accelererats genom besträl-ningsbehandlingen, som inte förorsakar väsentlig förlust 30 av hällfastheten hos elementet före implantationen i kroppen, i jämförelse med ett icke-besträlningsbehandlat element.
6. Förfarande för modifiering av ett kirurgiskt strukturelement enligt patentkravet 1, känneteck- 35. a t därav, att polymeren innehäller ett inert fyllme-del i en mängd av högst cirka 40 vikt-%. 24 8021 3
7. Förfarande för modifiering av ett kirurgiskt strukturelement enligt patentkravet 6, känneteck-n a t därav, att fyllmedlet är bariumsulfat.
8. Förfarande för modifiering av ett kirurgiskt 5 strukturelement enligt patentkravet 1, känneteck-n a t därav, att polymeren är polyglykolsyra. li
FI842435A 1983-06-16 1984-06-15 Modifiering av kirurgiska strukturelement innehållande polyglykol för erhållande av olika fysikaliska egenskaper in vivo FI80213C (sv)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/505,137 US4496446A (en) 1980-10-20 1983-06-16 Modification of polyglycolic acid structural elements to achieve variable in-vivo physical properties
US50513783 1983-06-16

Publications (4)

Publication Number Publication Date
FI842435A0 FI842435A0 (fi) 1984-06-15
FI842435A FI842435A (fi) 1984-12-17
FI80213B true FI80213B (fi) 1990-01-31
FI80213C FI80213C (sv) 1990-05-10

Family

ID=24009176

Family Applications (1)

Application Number Title Priority Date Filing Date
FI842435A FI80213C (sv) 1983-06-16 1984-06-15 Modifiering av kirurgiska strukturelement innehållande polyglykol för erhållande av olika fysikaliska egenskaper in vivo

Country Status (21)

Country Link
US (1) US4496446A (sv)
JP (1) JPH0624590B2 (sv)
KR (1) KR910008023B1 (sv)
AU (1) AU569891B2 (sv)
BE (1) BE899939A (sv)
BR (1) BR8402978A (sv)
CA (1) CA1247041A (sv)
CH (1) CH667586A5 (sv)
DE (1) DE3422160C2 (sv)
DK (1) DK160409C (sv)
ES (1) ES8700044A1 (sv)
FI (1) FI80213C (sv)
FR (1) FR2548904B1 (sv)
GB (1) GB2141435B (sv)
HK (1) HK10992A (sv)
IL (1) IL72205A (sv)
IT (1) IT1177803B (sv)
NL (1) NL191081C (sv)
NO (1) NO159238C (sv)
SE (1) SE461794B (sv)
ZA (1) ZA844569B (sv)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4594407A (en) * 1983-09-20 1986-06-10 Allied Corporation Prosthetic devices derived from krebs-cycle dicarboxylic acids and diols
US4650488A (en) * 1984-05-16 1987-03-17 Richards Medical Company Biodegradable prosthetic device
US4808351A (en) * 1985-03-25 1989-02-28 American Cyanamid Company Process for manufacturing a molded prosthetic device
DE3678191D1 (de) * 1985-03-25 1991-04-25 American Cyanamid Co Verfahren zur herstellung einer waermebehandelten prothetischen vorrichtung.
US4705820A (en) * 1986-09-05 1987-11-10 American Cyanamid Company Surgical suture coating
JP2860663B2 (ja) * 1989-06-28 1999-02-24 タキロン株式会社 生体内分解吸収性外科用成形物
US5366480A (en) * 1990-12-24 1994-11-22 American Cyanamid Company Synthetic elastomeric buttressing pledget
CA2060635A1 (en) * 1991-02-12 1992-08-13 Keith D'alessio Bioabsorbable medical implants
US5352515A (en) * 1992-03-02 1994-10-04 American Cyanamid Company Coating for tissue drag reduction
US5478355A (en) * 1993-03-18 1995-12-26 United States Surgical Corporation Method for improving the in vivo strength retention of a bioabsorbable implantable medical device and resulting medical device
US5702656A (en) * 1995-06-07 1997-12-30 United States Surgical Corporation Process for making polymeric articles
US6107453A (en) * 1995-07-28 2000-08-22 Sanitaria Scaligera S.P.A. Process of surface activation of biocompatible and bioabsorbable aliphatic polyesters and polyesters thus activated
IT1277799B1 (it) * 1995-07-28 1997-11-12 Sanitaria Scaligera Spa Procedimento di funzionalizzazione superficiale di poliesteri- alifatici biocompatibili e bioassorbibili e poliesteri cosi' attivati
FI954565A0 (fi) * 1995-09-27 1995-09-27 Biocon Oy Biolgiskt upploeslig av ett polymerbaserat material tillverkad implant och foerfarande foer dess tillverkning
JP3731839B2 (ja) 1996-04-30 2006-01-05 株式会社クレハ ポリグリコール酸射出成形物及びその製造方法
DE19721876A1 (de) * 1997-05-16 1998-11-19 Ethicon Gmbh Implantat und Verfahren zum Herstellen eines Implantats
US5889075A (en) * 1997-10-10 1999-03-30 United States Surgical Corporation Irradiated surgical suture and method for making same
US6423818B1 (en) * 1999-07-30 2002-07-23 Takehisa Matsuda Coumarin endcapped absorbable polymers
GB2367365B (en) 2000-10-02 2002-08-14 Strainstall Engineering Servic Measuring train parameters
NL1021843C2 (nl) * 2002-11-05 2004-05-07 Univ Twente Biomedische structuren van poly (1,3-trimethyleencarbonaat) (poly (TMC)).
GB0402838D0 (en) 2004-02-10 2004-03-17 Univ Belfast Method
DE102005006718A1 (de) * 2005-02-04 2006-08-17 Aesculap Ag & Co. Kg Resorbierbares chirurgisches Nahtmaterial
US20080175951A1 (en) 2007-01-23 2008-07-24 Rule David D Methods, apparatuses and systems of fermentation
US20090263458A1 (en) * 2008-04-21 2009-10-22 Lasse Daniel Efskind Material for surgical use in traumatology
WO2016126249A1 (en) 2015-02-04 2016-08-11 Rule David D Energy transfer systems and energy transfer methods
CN108271347B (zh) 2015-09-15 2021-04-20 萨维奇医疗股份有限公司 用于在组织腔中锚定护套的装置和方法

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2964455A (en) * 1956-11-05 1960-12-13 Du Pont Electron irradiation of organic polyethers
BE758156R (fr) * 1970-05-13 1971-04-28 Ethicon Inc Element de suture absorbable et sa
US3736646A (en) * 1971-10-18 1973-06-05 American Cyanamid Co Method of attaching surgical needles to multifilament polyglycolic acid absorbable sutures
US3867190A (en) * 1971-10-18 1975-02-18 American Cyanamid Co Reducing capillarity of polyglycolic acid sutures
JPS4936597A (sv) * 1972-08-07 1974-04-04
US4135622A (en) * 1973-03-28 1979-01-23 American Cyanamid Company Packaged, desiccated surgical elements
US3991766A (en) * 1973-05-31 1976-11-16 American Cyanamid Company Controlled release of medicaments using polymers from glycolic acid
US4048256A (en) * 1976-06-01 1977-09-13 American Cyanamid Company Normally-solid, bioabsorbable, hydrolyzable, polymeric reaction product
FR2364644B1 (fr) * 1976-09-20 1981-02-06 Inst Nat Sante Rech Med Nouveau materiau de prothese osseuse et son application
FR2439003A1 (fr) * 1978-10-20 1980-05-16 Anvar Nouvelles pieces d'osteosynthese, leur preparation et leur application
US4343931A (en) * 1979-12-17 1982-08-10 Minnesota Mining And Manufacturing Company Synthetic absorbable surgical devices of poly(esteramides)
DE3018966A1 (de) * 1980-05-17 1981-12-10 Bayer Ag, 5090 Leverkusen Mit organischem material beschichtetes baso (pfeil abwaerts)4(pfeil abwaerts) -pulver
DE3176533D1 (en) * 1980-10-20 1987-12-23 American Cyanamid Co Modification of polyglycolic acid to achieve variable in-vivo physical properties
US4689424A (en) * 1981-08-06 1987-08-25 Ethicon, Inc. Radiation sterilizable absorbable polymeric materials and methods for manufacturing the same

Also Published As

Publication number Publication date
ES8700044A1 (es) 1986-04-01
BR8402978A (pt) 1985-05-28
ZA844569B (en) 1986-02-26
GB8415139D0 (en) 1984-07-18
NO159238C (no) 1988-12-14
CH667586A5 (de) 1988-10-31
NL8401926A (nl) 1985-01-16
US4496446A (en) 1985-01-29
JPS6012068A (ja) 1985-01-22
DE3422160A1 (de) 1984-12-20
CA1247041A (en) 1988-12-20
HK10992A (en) 1992-01-31
IT1177803B (it) 1987-08-26
NO159238B (no) 1988-09-05
AU569891B2 (en) 1988-02-25
DK160409C (da) 1991-08-19
FI80213C (sv) 1990-05-10
GB2141435B (en) 1987-01-21
IL72205A (en) 1988-07-31
SE8403239L (sv) 1984-12-17
NO842420L (no) 1984-12-17
JPH0624590B2 (ja) 1994-04-06
ES533474A0 (es) 1986-04-01
DK296184D0 (da) 1984-06-15
KR910008023B1 (ko) 1991-10-07
BE899939A (fr) 1984-12-18
GB2141435A (en) 1984-12-19
IT8448411A0 (it) 1984-06-18
DK160409B (da) 1991-03-11
DK296184A (da) 1984-12-17
SE8403239D0 (sv) 1984-06-15
NL191081B (nl) 1994-08-16
NL191081C (nl) 1995-01-16
FR2548904B1 (fr) 1990-06-15
KR850000249A (ko) 1985-02-26
FR2548904A1 (fr) 1985-01-18
AU2943384A (en) 1984-12-20
DE3422160C2 (de) 1994-09-08
FI842435A0 (fi) 1984-06-15
FI842435A (fi) 1984-12-17
SE461794B (sv) 1990-03-26

Similar Documents

Publication Publication Date Title
FI80213B (fi) Modifiering av kirurgiska strukturelement innehaollande polyglykol foer erhaollande av olika fysikaliska egenskaper in vivo.
US6277397B1 (en) Collagen material and process for producing the same
EP1804850B1 (en) Bioabsorbable polymers comprising calcium carbonate
RU2207882C2 (ru) Измельченные полимерные гидрогели для исключения образования спаек и способы их получения
JP3251768B2 (ja) 吸収性ブロックコポリマー及びそれから製造された外科用物品
Gabrielli et al. Suture materials and other factors associated with tissue reactivity, infection, and wound dehiscence among plastic surgery outpatients
CN102973988B (zh) 一种可吸收血管结扎夹及其制备方法
US20100030261A1 (en) Surgical Sutures Having Increased Strength
CA1207942A (en) Modification of polyglycolic acid to achieve variable in-vivo physical properties
HRP20040486A2 (en) Controlled release polymeric compositions of bone growth promoting compounds
BR112014029242B1 (pt) blenda polimérica absorvível, biorsorvível ou biodegradável, dispositivo médico implantável e método de fabricação de um dispositivo médico implantável
CN103006288B (zh) 一种单层结构的v型血管结扎夹及其制备方法
ES2745057T3 (es) Fibras de monofilamento de poli (p-dioxanona-co-glicolida) absorbible que poseen retención de la resistencia a medio plazo después de la implantación
CA2160202C (en) Absorbable polymer and surgical articles fabricated therefrom
CN104940989A (zh) 一种可吸收缝合线及其制备方法
Wheeless Jr et al. The effect of growth hormone on the bursting strength of ileal anastomotic segments in radiation-injured rat bowel
CN113144274B (zh) 一种无抗原可吸收异形手术缝合线及其制备方法
JP2002003406A (ja) 脳血管攣縮予防製剤
ES2355699T3 (es) Polímeros reabsorbibles y artículos quirúrgicos fabricados de ellos.

Legal Events

Date Code Title Description
MM Patent lapsed
MM Patent lapsed

Owner name: AMERICAN CYANAMID COMPANY