FI78095C - Foerfarande foer framstaellning av som psykofarmaceutiska medel anvaendbara oxadiazolyl-imidazo/1,4/ bensodiazepinderivat. - Google Patents
Foerfarande foer framstaellning av som psykofarmaceutiska medel anvaendbara oxadiazolyl-imidazo/1,4/ bensodiazepinderivat. Download PDFInfo
- Publication number
- FI78095C FI78095C FI834137A FI834137A FI78095C FI 78095 C FI78095 C FI 78095C FI 834137 A FI834137 A FI 834137A FI 834137 A FI834137 A FI 834137A FI 78095 C FI78095 C FI 78095C
- Authority
- FI
- Finland
- Prior art keywords
- imidazo
- benzodiazepine
- oxadiazolyl
- methyl
- compounds
- Prior art date
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- CHKQALUEEULCPZ-UHFFFAOYSA-N amino 2,4,6-trimethylbenzenesulfonate Chemical compound CC1=CC(C)=C(S(=O)(=O)ON)C(C)=C1 CHKQALUEEULCPZ-UHFFFAOYSA-N 0.000 claims description 2
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Neurology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Plural Heterocyclic Compounds (AREA)
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
- Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
- Magnetic Resonance Imaging Apparatus (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DK510282A DK151808C (da) | 1982-11-16 | 1982-11-16 | Analogifremgangsmaade til fremstilling af oxadiazolylimidazo-oe1,4aa-benzodiazepinderivater |
| DK510282 | 1982-11-16 |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| FI834137A0 FI834137A0 (fi) | 1983-11-11 |
| FI834137A7 FI834137A7 (fi) | 1984-05-17 |
| FI78095B FI78095B (fi) | 1989-02-28 |
| FI78095C true FI78095C (fi) | 1989-06-12 |
Family
ID=8139462
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI834137A FI78095C (fi) | 1982-11-16 | 1983-11-11 | Foerfarande foer framstaellning av som psykofarmaceutiska medel anvaendbara oxadiazolyl-imidazo/1,4/ bensodiazepinderivat. |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US4507313A (https=) |
| EP (1) | EP0109921B1 (https=) |
| JP (1) | JPS59104385A (https=) |
| AT (1) | ATE32721T1 (https=) |
| DE (1) | DE3375785D1 (https=) |
| DK (1) | DK151808C (https=) |
| ES (3) | ES527295A0 (https=) |
| FI (1) | FI78095C (https=) |
| IE (1) | IE56233B1 (https=) |
| NO (1) | NO163820C (https=) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ZA845757B (en) * | 1983-08-25 | 1985-04-24 | Hoffmann La Roche | Benzodiazepine derivatives |
| FI850191A7 (fi) * | 1984-01-19 | 1985-07-20 | Hoffmann La Roche | Imidatsodiatsepiini-johdannaisia. |
| AU587802B2 (en) * | 1985-03-08 | 1989-08-31 | Ferrosan A/S | Novel oxadiazolyl imidazobenzodiazepine derivatives and methods of preparing such compounds |
| ATE38671T1 (de) * | 1985-05-17 | 1988-12-15 | Ferrosan As | Oxadiazolylimidazobenzodiazepine, verfahren zu ihrer herstellung und pharmazeutische zubereitungen. |
| US4745112A (en) * | 1985-05-17 | 1988-05-17 | A/S Ferrosan | Oxadiazolylimidazobenzodiazepine, compositions, and method III |
| US4622320A (en) * | 1985-05-17 | 1986-11-11 | As Ferrosan | Oxadiazolylimidazobenzodiazepine, compositions, and method |
| DK476885D0 (da) * | 1985-10-17 | 1985-10-17 | Ferrosan As | Heterocycliske forbindelser og fremgangsmaader til fremstilling heraf |
| CA1297099C (en) * | 1985-10-17 | 1992-03-10 | Frank Watjen | Quinazoline compounds and their preparation and use |
| DK174086D0 (da) * | 1986-04-16 | 1986-04-16 | Ferrosan As | Nye benzodiazepinderivater samt fremgangsmaade til fremstilling af samme |
| FI880814A7 (fi) * | 1987-03-10 | 1988-09-11 | Hoffmann La Roche | Imidazodiazepin-derivat. |
| GB8823475D0 (en) * | 1988-10-06 | 1988-11-16 | Merck Sharp & Dohme | Chemical compounds |
| CA2015336A1 (en) * | 1989-05-19 | 1990-11-19 | F. Hoffmann-La Roche Ag | Imidazodiazepines for the treatment of neurological symptoms |
| US4904654A (en) * | 1989-07-26 | 1990-02-27 | Merck & Co., Inc. | 7-chloro-5,6-dihydro-3-(5-(2-hydroxy-isopropyl)-1,2,4-oxadiazol-3-yl)-5-methyl-6-oxo-4H-imidazo[1,5a][1,4]benzodiazepine |
| US4939139A (en) * | 1989-07-26 | 1990-07-03 | Merck & Co., Inc. | 7-chloro-5,6-dihydro-3-(5-(1,2-dihydroxy-isopropyl)-1,2,4-oxadiazol-3-yl)-5-methyl-6-oxo-4H-imidazo[1,5A][1,4]benzodiazepine |
| GB8923008D0 (en) * | 1989-10-12 | 1989-11-29 | Roussel Lab Ltd | Chemical compounds |
| GB8927928D0 (en) * | 1989-12-11 | 1990-02-14 | Roussel Lab Ltd | Chemical compounds |
| US5428031A (en) * | 1991-12-03 | 1995-06-27 | Merck & Co., Inc. | Methods of treating cardiac arrhythmia |
| US5317018A (en) * | 1992-06-09 | 1994-05-31 | Armin Walser | Benzodiazepines and compositions for treating anxiety and panic disorders, and idiopathic and psychomotor epilepsy |
| US5439906A (en) * | 1993-11-22 | 1995-08-08 | Merck & Co., Inc. | Antiarrhythmic benzodiazepines |
| AU681924B2 (en) * | 1993-11-22 | 1997-09-11 | Merck & Co., Inc. | 3-acylaminobenzazepines |
| CA2143246C (en) * | 1994-03-16 | 2000-08-22 | Thierry Godel | Imidazodiazepines |
| SK282019B6 (sk) * | 1994-08-18 | 2001-10-08 | Merck & Co., Inc. | 2,3-dihydro-1-(2,2,2-trifluóretyl)-2-oxo-5-fenyl-1h-1,4- benzodiazepínové deriváty, farmaceutický prostriedok s ich obsahom a ich použitie |
| US5726171A (en) * | 1995-06-07 | 1998-03-10 | Merck & Co Inc | N-(1-alkyl-5-phenyl-2,3,4,5-tetrahydro-1H-benzo B! 1,4!diazepin-3yl)-acetamides |
| WO1996040656A1 (en) * | 1995-06-07 | 1996-12-19 | Merck & Co., Inc. | Novel n-(2,4-dioxo-2,3,4,5-tetrahydro-1h-1,5-benzodiazepin-3yl)-3-amides |
| US5700797A (en) * | 1995-06-07 | 1997-12-23 | Merck & Co, Inc. | N-(2,4-dioxo-2,3,4,5-tetrahydro-1H-1,5-benzodiazepin-3-yl)-3-amides |
| US5631251A (en) * | 1995-06-07 | 1997-05-20 | Merck & Co., Inc. | 5-cyclopropyl-1,4 benzodiazepine-2-ones |
| US5691331A (en) * | 1995-06-07 | 1997-11-25 | Merck & Co., Inc. | N-(2,4-Dioxo-2,3,4,5-tetrahydro-1H-1,5-benzodiazepin-3yl) -3- amides |
| WO2009024325A2 (en) * | 2007-08-20 | 2009-02-26 | Evotec Neurosciences Gmbh | Treatment of sleep disorders |
| US20090054412A1 (en) * | 2007-08-20 | 2009-02-26 | John Alan Kemp | Treatment of Sleep Disorders |
| US8119629B2 (en) | 2007-10-03 | 2012-02-21 | Bristol-Meyers Squibb Company | Carboxamide GABAA α2 modulators |
| US10071427B2 (en) * | 2014-09-05 | 2018-09-11 | Mazak Corporation | Vertical machine tool apparatus and method |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AT361486B (de) * | 1975-08-07 | 1981-03-10 | Hoffmann La Roche | Verfahren zur herstellung von neuen imidazo(1,5 -a) (1,4)diazepinverbindungen, ihren salzen und optisch aktiven formen |
| CA1143728A (en) * | 1979-10-04 | 1983-03-29 | Max Gerecke | Imidazodiazepine derivatives |
| JPS57123180A (en) * | 1980-12-17 | 1982-07-31 | Schering Ag | 3-substituted beta-carboline, manufacture and psychotropic drug containing same |
| CA1184175A (en) * | 1981-02-27 | 1985-03-19 | Walter Hunkeler | Imidazodiazepines |
| US4352817A (en) * | 1981-02-27 | 1982-10-05 | Hoffmann-La Roche Inc. | Imidazo-diazepines and their use |
| CA1174673A (en) * | 1981-02-27 | 1984-09-18 | Walter Hunkeler | Imidazodiazepines |
-
1982
- 1982-11-16 DK DK510282A patent/DK151808C/da not_active IP Right Cessation
-
1983
- 1983-11-11 FI FI834137A patent/FI78095C/fi not_active IP Right Cessation
- 1983-11-12 EP EP83730110A patent/EP0109921B1/en not_active Expired
- 1983-11-12 DE DE8383730110T patent/DE3375785D1/de not_active Expired
- 1983-11-12 AT AT83730110T patent/ATE32721T1/de not_active IP Right Cessation
- 1983-11-14 IE IE2644/83A patent/IE56233B1/xx unknown
- 1983-11-15 ES ES83527295A patent/ES527295A0/es active Granted
- 1983-11-15 US US06/551,818 patent/US4507313A/en not_active Expired - Lifetime
- 1983-11-15 NO NO834187A patent/NO163820C/no unknown
- 1983-11-15 JP JP58213456A patent/JPS59104385A/ja active Granted
-
1984
- 1984-01-25 ES ES529149A patent/ES529149A0/es active Granted
- 1984-01-25 ES ES529150A patent/ES529150A0/es active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| EP0109921B1 (en) | 1988-03-02 |
| ES8504196A1 (es) | 1985-04-16 |
| DE3375785D1 (en) | 1988-04-07 |
| JPS59104385A (ja) | 1984-06-16 |
| EP0109921A1 (en) | 1984-05-30 |
| DK151808C (da) | 1988-06-20 |
| ES8507143A1 (es) | 1985-09-01 |
| FI834137A7 (fi) | 1984-05-17 |
| DK510282A (da) | 1984-05-17 |
| NO834187L (no) | 1984-05-18 |
| ES8507144A1 (es) | 1985-09-01 |
| DK151808B (da) | 1988-01-04 |
| IE56233B1 (en) | 1991-05-22 |
| US4507313A (en) | 1985-03-26 |
| ES527295A0 (es) | 1985-04-16 |
| NO163820B (no) | 1990-04-17 |
| JPS635031B2 (https=) | 1988-02-01 |
| ES529149A0 (es) | 1985-09-01 |
| ATE32721T1 (de) | 1988-03-15 |
| FI834137A0 (fi) | 1983-11-11 |
| NO163820C (no) | 1990-08-01 |
| IE832644L (en) | 1984-05-15 |
| FI78095B (fi) | 1989-02-28 |
| ES529150A0 (es) | 1985-09-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM | Patent lapsed |
Owner name: A/S FERROSAN |