ES529149A0 - Metodo de preparar derivados de oxadiazolil-imidazo (1, 4) benzodiazepina - Google Patents

Metodo de preparar derivados de oxadiazolil-imidazo (1, 4) benzodiazepina

Info

Publication number
ES529149A0
ES529149A0 ES529149A ES529149A ES529149A0 ES 529149 A0 ES529149 A0 ES 529149A0 ES 529149 A ES529149 A ES 529149A ES 529149 A ES529149 A ES 529149A ES 529149 A0 ES529149 A0 ES 529149A0
Authority
ES
Spain
Prior art keywords
hydrogen
benzodiazepine
formula
image
oxadiazolil
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES529149A
Other languages
English (en)
Other versions
ES8507143A1 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ferrosan ApS
Original Assignee
Ferrosan ApS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ferrosan ApS filed Critical Ferrosan ApS
Publication of ES529149A0 publication Critical patent/ES529149A0/es
Publication of ES8507143A1 publication Critical patent/ES8507143A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
ES529149A 1982-11-16 1984-01-25 Metodo de preparar derivados de oxadiazolil-imidazo (1, 4) benzodiazepina Expired ES8507143A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DK510282A DK151808C (da) 1982-11-16 1982-11-16 Analogifremgangsmaade til fremstilling af oxadiazolylimidazo-oe1,4aa-benzodiazepinderivater

Publications (2)

Publication Number Publication Date
ES529149A0 true ES529149A0 (es) 1985-09-01
ES8507143A1 ES8507143A1 (es) 1985-09-01

Family

ID=8139462

Family Applications (3)

Application Number Title Priority Date Filing Date
ES83527295A Granted ES527295A0 (es) 1982-11-16 1983-11-15 Metodo de preparar derivados de oxadiazolil-imidazo (1,4) benzodiazepina
ES529149A Expired ES8507143A1 (es) 1982-11-16 1984-01-25 Metodo de preparar derivados de oxadiazolil-imidazo (1, 4) benzodiazepina
ES529150A Granted ES529150A0 (es) 1982-11-16 1984-01-25 Metodo de preparar derivados de oxadiazolil-imidazo (1, 4) benzodiazepina

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES83527295A Granted ES527295A0 (es) 1982-11-16 1983-11-15 Metodo de preparar derivados de oxadiazolil-imidazo (1,4) benzodiazepina

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES529150A Granted ES529150A0 (es) 1982-11-16 1984-01-25 Metodo de preparar derivados de oxadiazolil-imidazo (1, 4) benzodiazepina

Country Status (10)

Country Link
US (1) US4507313A (es)
EP (1) EP0109921B1 (es)
JP (1) JPS59104385A (es)
AT (1) ATE32721T1 (es)
DE (1) DE3375785D1 (es)
DK (1) DK151808C (es)
ES (3) ES527295A0 (es)
FI (1) FI78095C (es)
IE (1) IE56233B1 (es)
NO (1) NO163820C (es)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA845757B (en) * 1983-08-25 1985-04-24 Hoffmann La Roche Benzodiazepine derivatives
EP0150040B1 (de) * 1984-01-19 1994-08-31 F. Hoffmann-La Roche Ag Imidazodiazepin-Derivate
AU587802B2 (en) * 1985-03-08 1989-08-31 Ferrosan A/S Novel oxadiazolyl imidazobenzodiazepine derivatives and methods of preparing such compounds
US4622320A (en) * 1985-05-17 1986-11-11 As Ferrosan Oxadiazolylimidazobenzodiazepine, compositions, and method
DK476885D0 (da) * 1985-10-17 1985-10-17 Ferrosan As Heterocycliske forbindelser og fremgangsmaader til fremstilling heraf
DE3661197D1 (en) * 1985-05-17 1988-12-22 Ferrosan As Oxadiazolylimidazobenzodiazepines, process for their preparation and pharmaceutical compositions
US4745112A (en) * 1985-05-17 1988-05-17 A/S Ferrosan Oxadiazolylimidazobenzodiazepine, compositions, and method III
CA1297099C (en) * 1985-10-17 1992-03-10 Frank Watjen Quinazoline compounds and their preparation and use
DK174086D0 (da) * 1986-04-16 1986-04-16 Ferrosan As Nye benzodiazepinderivater samt fremgangsmaade til fremstilling af samme
FI880814A (fi) * 1987-03-10 1988-09-11 Hoffmann La Roche Imidazodiazepin-derivat.
GB8823475D0 (en) * 1988-10-06 1988-11-16 Merck Sharp & Dohme Chemical compounds
CA2015336A1 (en) * 1989-05-19 1990-11-19 F. Hoffmann-La Roche Ag Imidazodiazepines for the treatment of neurological symptoms
US4939139A (en) * 1989-07-26 1990-07-03 Merck & Co., Inc. 7-chloro-5,6-dihydro-3-(5-(1,2-dihydroxy-isopropyl)-1,2,4-oxadiazol-3-yl)-5-methyl-6-oxo-4H-imidazo[1,5A][1,4]benzodiazepine
US4904654A (en) * 1989-07-26 1990-02-27 Merck & Co., Inc. 7-chloro-5,6-dihydro-3-(5-(2-hydroxy-isopropyl)-1,2,4-oxadiazol-3-yl)-5-methyl-6-oxo-4H-imidazo[1,5a][1,4]benzodiazepine
GB8923008D0 (en) * 1989-10-12 1989-11-29 Roussel Lab Ltd Chemical compounds
GB8927928D0 (en) * 1989-12-11 1990-02-14 Roussel Lab Ltd Chemical compounds
US5428031A (en) * 1991-12-03 1995-06-27 Merck & Co., Inc. Methods of treating cardiac arrhythmia
US5317018A (en) * 1992-06-09 1994-05-31 Armin Walser Benzodiazepines and compositions for treating anxiety and panic disorders, and idiopathic and psychomotor epilepsy
DE69428546T2 (de) * 1993-11-22 2002-04-11 Merck & Co Inc 3-acylaminobenzazepine
US5439906A (en) * 1993-11-22 1995-08-08 Merck & Co., Inc. Antiarrhythmic benzodiazepines
CA2143246C (en) * 1994-03-16 2000-08-22 Thierry Godel Imidazodiazepines
ES2139933T3 (es) * 1994-08-18 2000-02-16 Merck & Co Inc 2,3-dihidro-1-(2,2,2-trifluoroetil)-2-oxo-5-fenil-1h-1,4-benzodiacepinas.
US5726171A (en) * 1995-06-07 1998-03-10 Merck & Co Inc N-(1-alkyl-5-phenyl-2,3,4,5-tetrahydro-1H-benzo B! 1,4!diazepin-3yl)-acetamides
CA2222491A1 (en) * 1995-06-07 1996-12-19 Merck & Co., Inc. Novel n-(2,4-dioxo-2,3,4,5-tetrahydro-1h-1,5-benzodiazepin-3yl)-3-amides
US5691331A (en) * 1995-06-07 1997-11-25 Merck & Co., Inc. N-(2,4-Dioxo-2,3,4,5-tetrahydro-1H-1,5-benzodiazepin-3yl) -3- amides
US5631251A (en) * 1995-06-07 1997-05-20 Merck & Co., Inc. 5-cyclopropyl-1,4 benzodiazepine-2-ones
US5700797A (en) * 1995-06-07 1997-12-23 Merck & Co, Inc. N-(2,4-dioxo-2,3,4,5-tetrahydro-1H-1,5-benzodiazepin-3-yl)-3-amides
KR101589314B1 (ko) 2007-08-20 2016-01-28 에보텍 인터내셔널 게엠베하 수면 장애의 치료
US20090054412A1 (en) * 2007-08-20 2009-02-26 John Alan Kemp Treatment of Sleep Disorders
US8119629B2 (en) 2007-10-03 2012-02-21 Bristol-Meyers Squibb Company Carboxamide GABAA α2 modulators
WO2016037111A1 (en) * 2014-09-05 2016-03-10 Mazak Corporation Vertical machine tool apparatus and method

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU509371B2 (en) * 1975-08-07 1980-05-08 F. Hoffmann-La Roche Ag Diazepine Derivatives
CA1143728A (en) * 1979-10-04 1983-03-29 Max Gerecke Imidazodiazepine derivatives
JPS57123180A (en) * 1980-12-17 1982-07-31 Schering Ag 3-substituted beta-carboline, manufacture and psychotropic drug containing same
CA1184175A (en) * 1981-02-27 1985-03-19 Walter Hunkeler Imidazodiazepines
CA1174673A (en) * 1981-02-27 1984-09-18 Walter Hunkeler Imidazodiazepines
US4352817A (en) * 1981-02-27 1982-10-05 Hoffmann-La Roche Inc. Imidazo-diazepines and their use

Also Published As

Publication number Publication date
ES8507144A1 (es) 1985-09-01
FI834137A0 (fi) 1983-11-11
FI78095B (fi) 1989-02-28
ES8504196A1 (es) 1985-04-16
US4507313A (en) 1985-03-26
EP0109921B1 (en) 1988-03-02
ES527295A0 (es) 1985-04-16
DK151808B (da) 1988-01-04
ES529150A0 (es) 1985-09-01
JPS59104385A (ja) 1984-06-16
DK510282A (da) 1984-05-17
EP0109921A1 (en) 1984-05-30
DK151808C (da) 1988-06-20
ATE32721T1 (de) 1988-03-15
FI78095C (fi) 1989-06-12
NO834187L (no) 1984-05-18
NO163820B (no) 1990-04-17
FI834137A (fi) 1984-05-17
JPS635031B2 (es) 1988-02-01
DE3375785D1 (en) 1988-04-07
ES8507143A1 (es) 1985-09-01
NO163820C (no) 1990-08-01
IE56233B1 (en) 1991-05-22
IE832644L (en) 1984-05-15

Similar Documents

Publication Publication Date Title
ES527295A0 (es) Metodo de preparar derivados de oxadiazolil-imidazo (1,4) benzodiazepina
ES539663A0 (es) Un procedimiento para la preparacion de derivados de imida- zodiacepina
KR850003890A (ko) 1H-이미다조[4,5c]-퀴놀린-4-아민의 제조방법
ES2162871T3 (es) Derivados oxindoles sustituidos en la posicion 3 de accion biologica, utiles como agentes anti-angiogenicos.
ES8500948A1 (es) Un procedimiento para la preparacion de derivados de acilmorrfinano.
ZA858418B (en) 5-alkyl-1-phenyl-2-piperazinoalkylpyrazoline-3-one compounds and methods for the preparation thereof,intermediates for use in the preparation of said compounds and medicaments containing said compounds
DK301689A (da) 4,5,7,8-tetrahydro-6h-thiazolooe5,4-daaazepiner samt laegemidler med indhold af saadenne forbindelser
FI99014B (fi) Menetelmä uusien terapeuttisesti käyttökelpoisten bentsotieno[2,3-b]pyratsiini-2,3(1H,4H)-dionien valmistamiseksi
DE3776443D1 (de) Pyrimidinderivate und verfahren zu ihrer herstellung.
MX9204194A (es) Los compuestos de 1,2,4-oxadiazolil-fenoxialquilisoxazolas y su uso como agentes antivirales
DK123685A (da) Analogifremgangsmaade til fremstilling af oxadiazolylimidazo-(1,4)-benzodiazepinderivater
EP0462468A3 (en) 9-amino-2-phenylbicyclo(3.3.1)nonane and 9-amino-2-phenylbicyclo(3.3.1)-non-2-ene and therapeutic agents containing them
CA1251790A (en) PYRROLE[1,2-B][1,2,5] TRIAZEPINES, METHOD AND INTERMEDIATES FOR THEIR PREPARATION AND USE AS MEDICINES
GB2020282A (en) 5,6-Dihydro-5-thioxopyrazolo [1,5-c]quinazoline derivatives
FR2592652A1 (fr) Nouvelles phenyl-naphtyridines, leur procede de preparation et les medicaments en contenant.