FI752327A - - Google Patents

Info

Publication number
FI752327A
FI752327A FI752327A FI752327A FI752327A FI 752327 A FI752327 A FI 752327A FI 752327 A FI752327 A FI 752327A FI 752327 A FI752327 A FI 752327A FI 752327 A FI752327 A FI 752327A
Authority
FI
Finland
Application number
FI752327A
Other languages
Finnish (fi)
Other versions
FI63756B (fi
FI63756C (fi
Inventor
Peder Bernhard Berntsson
Stig Aoke Ingemar Carlsson
Lars Erik Garberg
Ulf Krister Junggren
Sven Erik Sjoestrand
Gunhild Wika V Wittken-Sundell
Original Assignee
Haessle Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to SE7406513A priority Critical patent/SE416649B/xx
Application filed by Haessle Ab filed Critical Haessle Ab
Priority to FI752327A priority patent/FI63756C/fi
Priority to NO75752851A priority patent/NO143222C/no
Priority to DK372175AA priority patent/DK140840B/da
Priority to ZA00756600A priority patent/ZA756600B/xx
Priority to GB43039/75A priority patent/GB1525958A/en
Priority to CY1125A priority patent/CY1125A/xx
Priority to IE2313/75A priority patent/IE42451B1/en
Priority to DE19752548340 priority patent/DE2548340A1/de
Priority to AT838075A priority patent/AT337697B/de
Priority to CS757458A priority patent/CS196289B2/cs
Priority to NL7513141A priority patent/NL7513141A/xx
Priority to US05/630,916 priority patent/US4045563A/en
Priority to HU75HE00000696A priority patent/HU172653B/hu
Priority to SU752189960A priority patent/SU602118A3/ru
Priority to FR7534910A priority patent/FR2331340A1/fr
Priority to CA239,643A priority patent/CA1055033A/en
Priority to CH1481475A priority patent/CH623814A5/de
Priority to DD189463A priority patent/DD122534A5/xx
Priority to JP50137712A priority patent/JPS5262275A/ja
Priority to FR7616732A priority patent/FR2392021A1/fr
Priority to AT752276A priority patent/AT351524B/de
Publication of FI752327A publication Critical patent/FI752327A/fi
Priority to DK783659A priority patent/DK365978A/da
Priority to CS786886A priority patent/CS196290B2/cs
Priority to CH976079A priority patent/CH623582A5/de
Priority to FI811747A priority patent/FI65617C/fi
Priority to HK87/82A priority patent/HK8782A/xx
Priority to MY159/82A priority patent/MY8200159A/xx
Publication of FI63756B publication Critical patent/FI63756B/fi
Application granted granted Critical
Publication of FI63756C publication Critical patent/FI63756C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D235/28—Sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
FI752327A 1974-05-16 1975-08-15 Foerfarande foer framstaellning av 2-(2-pyridylmetylsulfinyl)-bensimidazolderivat med magsyrasekretionsinhiberande verkan FI63756C (fi)

Priority Applications (28)

Application Number Priority Date Filing Date Title
SE7406513A SE416649B (sv) 1974-05-16 1974-05-16 Forfarande for framstellning av foreningar som paverkar magsyrasekretionen
FI752327A FI63756C (fi) 1974-05-16 1975-08-15 Foerfarande foer framstaellning av 2-(2-pyridylmetylsulfinyl)-bensimidazolderivat med magsyrasekretionsinhiberande verkan
NO75752851A NO143222C (no) 1974-05-16 1975-08-15 Analogifremgangsmaate for fremstilling av nye substituerte pyridylsulfinyl-benzimidazoler med terapeutisk aktivitet
DK372175AA DK140840B (da) 1974-05-16 1975-08-18 Analogifremgangsmåde til fremstilling af benzimidazolderivater eller syreadditionssalte deraf.
ZA00756600A ZA756600B (en) 1974-05-16 1975-10-20 Gastric acid secretion agents
GB43039/75A GB1525958A (en) 1974-05-16 1975-10-20 2-(heterocyclic substituted alkylsulphinyl)-benzimidazoles and their pharmaceutical compositions
CY1125A CY1125A (en) 1974-05-16 1975-10-20 2-(heterocaclic asbstituted alkylsulphinyl)-benzinmidazoles and their pharmaceutical compositions
IE2313/75A IE42451B1 (en) 1974-05-16 1975-10-23 2-(heterocyclic substituted alkylsulphinyl)-benzimidazoles and their pharmaceutical compositions
DE19752548340 DE2548340A1 (de) 1974-05-16 1975-10-29 Benzimidazole, verfahren zu deren herstellung und sie enthaltende mittel
AT838075A AT337697B (de) 1974-05-16 1975-11-04 Verfahren zur herstellung von neuen benzimidazolderivaten und ihren salzen
CS757458A CS196289B2 (en) 1974-05-16 1975-11-05 Process for preparing new compounds
NL7513141A NL7513141A (nl) 1974-05-16 1975-11-10 Benzimidazoolderivaten en werkwijze voor het be- reiden daarvan alsmede preparaten voor het bein- vloeden van de maagzuursecretie.
US05/630,916 US4045563A (en) 1974-05-16 1975-11-11 Substituted 2-[pyridylalkylenesulfinyl]-benzimidazoles with gastric acid secretion inhibiting effects
HU75HE00000696A HU172653B (hu) 1974-05-16 1975-11-12 Sposob poluchenija zamehhennykh 2-skobka-2-piridil-metil-sul'finil-skobka zakryta-benzimidazolov
SU752189960A SU602118A3 (ru) 1974-05-16 1975-11-13 Способ получени производных бензимидазола или их солей
FR7534910A FR2331340A1 (fr) 1974-05-16 1975-11-14 Nouveaux derives du benzimidazole, procede pour leur obtention et compositions pharmaceutiques les contenant
CA239,643A CA1055033A (en) 1974-05-16 1975-11-14 2-(2-heterocyclic-methylsulphinyl)-benzimidazole compounds
CH1481475A CH623814A5 (en) 1974-05-16 1975-11-14 Process for the preparation of novel benzimidazoles
DD189463A DD122534A5 (ru) 1974-05-16 1975-11-14
JP50137712A JPS5262275A (en) 1974-05-16 1975-11-15 Production of organic compound
FR7616732A FR2392021A1 (fr) 1974-05-16 1976-06-03 Nouveaux derives du benzimidazole et procede pour leur obtention
AT752276A AT351524B (de) 1974-05-16 1976-10-11 Verfahren zur herstellung von neuen benzimida- zolderivaten, ihren salzen und optischen isomeren
DK783659A DK365978A (da) 1974-05-16 1978-08-18 Mellemprodukt til anvendelse ved fremstilling af benzimidazolderivater
CS786886A CS196290B2 (en) 1974-05-16 1978-10-23 Process for preparing new compounds
CH976079A CH623582A5 (en) 1974-05-16 1979-10-31 Process for the preparation of benzimidazoles
FI811747A FI65617C (fi) 1974-05-16 1981-06-04 Mellanprodukt foer framstaellning av magsyrasekretionsinhiberande 2-(2-pyridylmetylsulfinyl)-benzimidazolderivat
HK87/82A HK8782A (en) 1974-05-16 1982-02-25 2-(heterocyclic substituted alkylsulphinyl)-benzimidazoles and their pharmaceutical compositions
MY159/82A MY8200159A (en) 1974-05-16 1982-12-30 2-[heterocylic substituted alkylsulphinyl]-benzimidazoles and their pharmaceutical compositions

Applications Claiming Priority (50)

Application Number Priority Date Filing Date Title
SE7406513 1974-05-16
SE7406513A SE416649B (sv) 1974-05-16 1974-05-16 Forfarande for framstellning av foreningar som paverkar magsyrasekretionen
NO75752851A NO143222C (no) 1974-05-16 1975-08-15 Analogifremgangsmaate for fremstilling av nye substituerte pyridylsulfinyl-benzimidazoler med terapeutisk aktivitet
FI752327 1975-08-15
FI752327A FI63756C (fi) 1974-05-16 1975-08-15 Foerfarande foer framstaellning av 2-(2-pyridylmetylsulfinyl)-bensimidazolderivat med magsyrasekretionsinhiberande verkan
NO752851 1975-08-15
DK372175 1975-08-18
DK372175AA DK140840B (da) 1974-05-16 1975-08-18 Analogifremgangsmåde til fremstilling af benzimidazolderivater eller syreadditionssalte deraf.
GB43039/75A GB1525958A (en) 1974-05-16 1975-10-20 2-(heterocyclic substituted alkylsulphinyl)-benzimidazoles and their pharmaceutical compositions
ZA00756600A ZA756600B (en) 1974-05-16 1975-10-20 Gastric acid secretion agents
GB4303975 1975-10-20
ZA7506600 1975-10-20
IE2313/75A IE42451B1 (en) 1974-05-16 1975-10-23 2-(heterocyclic substituted alkylsulphinyl)-benzimidazoles and their pharmaceutical compositions
IE231375 1975-10-23
DE2548340 1975-10-29
DE19752548340 DE2548340A1 (de) 1974-05-16 1975-10-29 Benzimidazole, verfahren zu deren herstellung und sie enthaltende mittel
AT838075A AT337697B (de) 1974-05-16 1975-11-04 Verfahren zur herstellung von neuen benzimidazolderivaten und ihren salzen
AT838075 1975-11-04
CS757458A CS196289B2 (en) 1974-05-16 1975-11-05 Process for preparing new compounds
CS745875 1975-11-05
NL7513141A NL7513141A (nl) 1974-05-16 1975-11-10 Benzimidazoolderivaten en werkwijze voor het be- reiden daarvan alsmede preparaten voor het bein- vloeden van de maagzuursecretie.
NL7513141 1975-11-10
US63091675 1975-11-11
US05/630,916 US4045563A (en) 1974-05-16 1975-11-11 Substituted 2-[pyridylalkylenesulfinyl]-benzimidazoles with gastric acid secretion inhibiting effects
HUHE000696 1975-11-12
HU75HE00000696A HU172653B (hu) 1974-05-16 1975-11-12 Sposob poluchenija zamehhennykh 2-skobka-2-piridil-metil-sul'finil-skobka zakryta-benzimidazolov
SU2189960 1975-11-13
SU752189960A SU602118A3 (ru) 1974-05-16 1975-11-13 Способ получени производных бензимидазола или их солей
FR7534910A FR2331340A1 (fr) 1974-05-16 1975-11-14 Nouveaux derives du benzimidazole, procede pour leur obtention et compositions pharmaceutiques les contenant
CH1481475A CH623814A5 (en) 1974-05-16 1975-11-14 Process for the preparation of novel benzimidazoles
FR7534910 1975-11-14
CA239643 1975-11-14
DD189463A DD122534A5 (ru) 1974-05-16 1975-11-14
DD18946375 1975-11-14
CA239,643A CA1055033A (en) 1974-05-16 1975-11-14 2-(2-heterocyclic-methylsulphinyl)-benzimidazole compounds
CH1481475 1975-11-14
JP50137712A JPS5262275A (en) 1974-05-16 1975-11-15 Production of organic compound
JP13771275 1975-11-15
FR7616732 1976-06-03
FR7616732A FR2392021A1 (fr) 1974-05-16 1976-06-03 Nouveaux derives du benzimidazole et procede pour leur obtention
AT752276 1976-10-11
AT752276A AT351524B (de) 1974-05-16 1976-10-11 Verfahren zur herstellung von neuen benzimida- zolderivaten, ihren salzen und optischen isomeren
DK365978 1978-08-18
DK783659A DK365978A (da) 1974-05-16 1978-08-18 Mellemprodukt til anvendelse ved fremstilling af benzimidazolderivater
CS786886A CS196290B2 (en) 1974-05-16 1978-10-23 Process for preparing new compounds
CS688678 1978-10-23
HU8782 1982-02-25
HU8782 1982-02-25
MY8200159 1982-12-30
MY159/82A MY8200159A (en) 1974-05-16 1982-12-30 2-[heterocylic substituted alkylsulphinyl]-benzimidazoles and their pharmaceutical compositions

Publications (3)

Publication Number Publication Date
FI752327A true FI752327A (ru) 1977-02-16
FI63756B FI63756B (fi) 1983-04-29
FI63756C FI63756C (fi) 1983-08-10

Family

ID=40486266

Family Applications (2)

Application Number Title Priority Date Filing Date
FI752327A FI63756C (fi) 1974-05-16 1975-08-15 Foerfarande foer framstaellning av 2-(2-pyridylmetylsulfinyl)-bensimidazolderivat med magsyrasekretionsinhiberande verkan
FI811747A FI65617C (fi) 1974-05-16 1981-06-04 Mellanprodukt foer framstaellning av magsyrasekretionsinhiberande 2-(2-pyridylmetylsulfinyl)-benzimidazolderivat

Family Applications After (1)

Application Number Title Priority Date Filing Date
FI811747A FI65617C (fi) 1974-05-16 1981-06-04 Mellanprodukt foer framstaellning av magsyrasekretionsinhiberande 2-(2-pyridylmetylsulfinyl)-benzimidazolderivat

Country Status (22)

Country Link
US (1) US4045563A (ru)
JP (1) JPS5262275A (ru)
AT (2) AT337697B (ru)
CA (1) CA1055033A (ru)
CH (2) CH623814A5 (ru)
CS (2) CS196289B2 (ru)
CY (1) CY1125A (ru)
DD (1) DD122534A5 (ru)
DE (1) DE2548340A1 (ru)
DK (2) DK140840B (ru)
FI (2) FI63756C (ru)
FR (2) FR2331340A1 (ru)
GB (1) GB1525958A (ru)
HK (1) HK8782A (ru)
HU (1) HU172653B (ru)
IE (1) IE42451B1 (ru)
MY (1) MY8200159A (ru)
NL (1) NL7513141A (ru)
NO (1) NO143222C (ru)
SE (1) SE416649B (ru)
SU (1) SU602118A3 (ru)
ZA (1) ZA756600B (ru)

Families Citing this family (126)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IN148930B (ru) * 1977-09-19 1981-07-25 Hoffmann La Roche
AT406119B (de) * 1978-04-14 2000-02-25 Haessle Ab Verfahren zur herstellung von granulaten bzw. tabletten oder kapseln zur oralen verabreichung
AT375365B (de) * 1978-04-14 1984-07-25 Haessle Ab Verfahren zur herstellung von neuen 2-pyridylalkyl-sulfinyl-benzimidazolen, von deren hydraten, stereoisomeren und salzen
SE7804231L (sv) * 1978-04-14 1979-10-15 Haessle Ab Magsyrasekretionsmedel
US4359465A (en) * 1980-07-28 1982-11-16 The Upjohn Company Methods for treating gastrointestinal inflammation
CH644116A5 (de) * 1980-08-21 1984-07-13 Hoffmann La Roche Imidazolderivate.
IL66340A (en) * 1981-08-13 1986-08-31 Haessle Ab Pharmaceutical compositions comprising pyridylmethyl-thiobenzimidazole derivatives,certain such novel derivatives and their preparation
JPS58135881A (ja) * 1981-11-05 1983-08-12 ビク−グルデン・ロムベルク・ヘミツシエ・フアブリク・ゲゼルシヤフト・ミト・ベシユレンクテル・ハフツング 置換ベンズイミダゾ−ル類、その製造方法と利用、およびこれを含む医薬
US4472409A (en) * 1981-11-05 1984-09-18 Byk Gulden Lomberg Chemische Fabrik Gesellschaft Mit Beschrankter Haftung 2-Pyridylmethyl thio(sulfinyl)benzimidazoles with gastric acid secretion inhibiting effects
DE3216843C2 (de) * 1982-05-05 1986-10-23 Ludwig Heumann & Co GmbH, 8500 Nürnberg 3-Thiomethyl-pyridin-Derivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
SE8300736D0 (sv) * 1983-02-11 1983-02-11 Haessle Ab Novel pharmacologically active compounds
SE8301182D0 (sv) * 1983-03-04 1983-03-04 Haessle Ab Novel compounds
HU195220B (en) * 1983-05-03 1988-04-28 Byk Gulden Lomberg Chem Fqb Process for production of new fluor-alkoxi-benzimidasole-derivatives and medical compositions containig them
HU191757B (en) * 1983-05-03 1987-04-28 Byk Gulden Lomberg Chem Fab Process for producing new tricyclic ethers
US5077407A (en) * 1983-07-01 1991-12-31 The Upjohn Company Substituted 2-[monoannelated (3,4-,4,5-, and 5,6-) pyridylalkylenesulfinyl]benzimidazoles
CA1259070A (en) * 1983-07-01 1989-09-05 Upjohn Company (The) Substituted 2-¬monoannelated(3,4-,4,5-, and 5,6-)- pyridylalkylenesulfinyl|-benzimidazoles
DE3333314A1 (de) * 1983-09-15 1985-03-28 Hoechst Ag, 6230 Frankfurt Substituierte pyrido(1,2-c)imidazo(1,2-a)benzimidazole, verfahren zu ihrer herstellung, ihre verwendung sowie pharmazeutische praeparate auf basis dieser verbindungen
US4575554A (en) * 1983-12-05 1986-03-11 The Upjohn Company Substituted 2-pyridylmethylthio- and sulfinyl-benzimidazoles as gastric antisecretory agents
PH23995A (en) * 1984-01-09 1990-02-09 Janssen Pharmaceutica Nv 4((bicycle heterocyclyl)-methyl and hetero)piperidines
CA1341314C (en) * 1984-07-06 2001-11-06 David Cox Derivatives of benzimidazole, benzothiazole and benzoxazole
SE8404065D0 (sv) * 1984-08-10 1984-08-10 Haessle Ab Novel biologically active compounds
JPS6150979A (ja) * 1984-08-16 1986-03-13 Takeda Chem Ind Ltd ピリジン誘導体およびその製造法
JPS6150978A (ja) * 1984-08-16 1986-03-13 Takeda Chem Ind Ltd ピリジン誘導体およびその製造法
US4619997A (en) * 1984-09-06 1986-10-28 The Upjohn Company Substituted 2-pyridylmethylthio and sulfinyl-benzimidazoles as gastric antisecretory agents
KR890000387B1 (ko) * 1984-09-24 1989-03-16 디 엎존 캄파니 2-(피리딜알켄술 피닐)벤즈 이미드아졸류의 n-치환 유도체의 제조방법
AU568441B2 (en) * 1984-09-24 1987-12-24 Upjohn Company, The 2-(pyridylalkenesulfinyl) benzimidazole derivatives
DE3579436D1 (de) * 1984-12-18 1990-10-04 Otsuka Pharma Co Ltd Tetrahydrochinolin- derivate, verfahren zu deren herstellung und diese enthaltende antimagengeschwuerzusammensetzungen.
GB8526154D0 (en) * 1985-02-06 1985-11-27 Kotobuki Seiyaku Co Ltd 2-substituted cyclo-heptoimidazoles
DK8600939A (ru) * 1985-03-05 1986-09-06
FI861772A (fi) * 1985-05-07 1986-11-08 Chemie Linz Ag Nya tieno(2,3-d)imidazolderivat och foerfarande for deras framstaellning.
US5869513A (en) * 1985-05-24 1999-02-09 G. D. Searle & Co. 2- (1H-benzimidazol-2-ylsulfinyl)methyl!benzenamines
AU5768886A (en) 1985-05-24 1986-11-27 G.D. Searle & Co. 2-((1-h-benzimidazol-2-ylsulfinyl)methyl)benzenamines
US4738975A (en) * 1985-07-02 1988-04-19 Takeda Chemical Industries, Ltd. Pyridine derivatives, and use as anti-ulcer agents
DK337086A (da) * 1985-08-12 1987-02-13 Hoffmann La Roche Benzimidazolderivater
AR243167A1 (es) 1985-08-24 1993-07-30 Hoechst Ag Procedimiento para la preparacion de toluidinas sustituidas.
SE8505112D0 (sv) * 1985-10-29 1985-10-29 Haessle Ab Novel pharmacological compounds
US6749864B2 (en) * 1986-02-13 2004-06-15 Takeda Chemical Industries, Ltd. Stabilized pharmaceutical composition
US5433959A (en) * 1986-02-13 1995-07-18 Takeda Chemical Industries, Ltd. Stabilized pharmaceutical composition
SE8600658D0 (sv) * 1986-02-14 1986-02-14 Haessle Ab Novel composition of matter
ES2032394T3 (es) 1986-02-20 1993-02-16 Hoechst Aktiengesellschaft Procedimiento para preparar derivados de tienoimidazol sustituidos.
WO1987005296A1 (en) * 1986-03-07 1987-09-11 Pfizer Inc. 2-[(2-pyridyl)methylsulfinyl]thienoimidazoles and related compounds as antiulcer agents
US4963566A (en) * 1986-03-28 1990-10-16 Otsuka Pharmaceutical Co., Ltd. Benzimidazolyl-sulfinyl-tetrahydroquinolines
US4687775A (en) * 1986-07-17 1987-08-18 G. D. Searle & Co. 2-[(Imidazo[1,2-a]pyridinylmethyl)sulfinyl]-1H-benzimidazoles
US4772619A (en) * 1986-07-17 1988-09-20 G. D. Searle & Co. [(1H-benzimidazol-2-ylsulfinyl)methyl]-2-pyridinamines
US4721718A (en) * 1986-08-18 1988-01-26 G. D. Searle & Co. 2-[(imidazo[1,2-a]pyridin-3-ylmethyl)sulfinyl]-1H-benzimidazoles useful in the treatment and prevention of ulcers
NZ234564A (en) 1986-11-21 1991-04-26 Haessle Ab 1-substituted benzimidazoles and pharmaceutical compositions
SE8604998D0 (sv) 1986-11-21 1986-11-21 Haessle Ab Novel pharmacological compounds
DE3639926A1 (de) * 1986-11-22 1988-06-01 Hoechst Ag Substituierte thienoimidazoltoluidin-derivate, verfahren zu ihrer herstellung, sie enthaltende pharmazeutische zubereitungen und ihre verwendung als magensaeuresekretionshemmer
US5330982A (en) * 1986-12-17 1994-07-19 Glaxo Group Limited Pharmaceutical composition containing a 5-HT receptor antagonist and an H+ K+ Atpase inhibitor and a method of treating gastrointestingal disorders therewith
GB8630080D0 (en) * 1986-12-17 1987-01-28 Glaxo Group Ltd Medicaments
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SU602118A3 (ru) 1978-04-05
CH623582A5 (en) 1981-06-15
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CS196290B2 (en) 1980-03-31
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CA1055033A (en) 1979-05-22
FI65617C (fi) 1984-06-11
DK365978A (da) 1978-08-18
JPS6128673B2 (ru) 1986-07-01
FI65617B (fi) 1984-02-29
ATA838075A (de) 1976-11-15
IE42451B1 (en) 1980-08-13
DK372175A (ru) 1977-02-19
US4045563A (en) 1977-08-30
FI811747L (fi) 1981-06-04
GB1525958A (en) 1978-09-27
CS196289B2 (en) 1980-03-31
SE7406513L (sv) 1975-11-17
FI63756B (fi) 1983-04-29
FR2392021A1 (fr) 1978-12-22
HK8782A (en) 1982-03-05
NO143222C (no) 1981-01-02
NO752851L (ru) 1977-02-16
DK140840C (ru) 1980-05-05
FR2331340B1 (ru) 1979-01-19
AT351524B (de) 1979-07-25
DE2548340C2 (ru) 1987-12-03
DE2548340A1 (de) 1977-05-05
DD122534A5 (ru) 1976-10-12
FR2392021B1 (ru) 1979-08-17
ATA752276A (de) 1979-01-15
ZA756600B (en) 1976-09-29
SE416649B (sv) 1981-01-26
NL7513141A (nl) 1977-05-12
HU172653B (hu) 1978-11-28
FR2331340A1 (fr) 1977-06-10
NO143222B (no) 1980-09-22
JPS5262275A (en) 1977-05-23
CH623814A5 (en) 1981-06-30
AT337697B (de) 1977-07-11
FI63756C (fi) 1983-08-10
MY8200159A (en) 1982-12-31

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